Michael Way
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drmichaelway.bsky.social
Michael Way
@drmichaelway.bsky.social
Cell Biologist working at Crick Institute @crick.ac.uk - Cytoskeleton, Arp2/3 iso-complexes, Signalling and Vaccinia Virus. Editor-in chief Journal Cell Science - @jcellsci.bsky.social - comments are my own opinion
Pinned
Last tweet on X.....Echo & The Bunnymen - "In Bluer Skies"
youtube.com/watch?v=8MKo...
As the lyrics say - What needs must be, I realized, I'm walking out, From blackened skies.......What needs have been, You'll realize, I've found myself, In bluer skies
....Come find me
@drmichaelway.bsky.social
youtube.com
Reposted by Michael Way
We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you.

Application deadline: 24 December

www.crick.ac.uk/careers-stud...
Postdoctoral Fellow - H Yardimci Lab
www.crick.ac.uk
November 25, 2025 at 11:55 AM
how do they do if you lower the temp?
So i'm usually interested about how cells divide in the cold, but couldnt resist helping out a tiny bit for a Euk dividing at 63°C.
Congrats to the whole team @hbrappap.bsky.social & Kudos to @fmikus.bsky.social for yet again the almighty #UExM !
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
November 25, 2025 at 8:59 PM
wow....just wondering if they might also have Mimiviruses.......as wouldn't want to meet one of them!
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
November 25, 2025 at 8:57 PM
Reposted by Michael Way
Excited to share our new lab website! angikabasantlab.academic.ws
November 25, 2025 at 12:50 PM
Reposted by Michael Way
Did you know that @jcellsci.bsky.social has a new editor for neuronal cell biology? It's that guy @roylab-ucsd.bsky.social, I've heard good things about him
Interview with Journal of Cell Science Editor Subhojit Roy
ABSTRACT. Subhojit Roy is Professor of Pathology at the University of California San Diego (UCSD) in the USA. Subhojit completed his MD in Kolkata, India and then moved to Temple University in Philade...
journals.biologists.com
November 24, 2025 at 4:14 PM
Reposted by Michael Way
A novel antiviral role of ankyrin repeat and LEM domain-containing 2 (ANKLE2) in restricting vaccinia virus through barrier to autointegration factor (BAF) | Journal of Virology journals.asm.org/doi/10.1128/...
A novel antiviral role of ankyrin repeat and LEM domain-containing 2 (ANKLE2) in restricting vaccinia virus through barrier to autointegration factor (BAF) | Journal of Virology
Vaccinia virus relies on disabling host defenses to replicate efficiently, with the host DNA-binding protein BAF representing a key target for viral kinases. Here, we uncover ANKLE2 as a critical host...
journals.asm.org
November 20, 2025 at 8:24 PM
Reposted by Michael Way
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
RAF inhibitors activate the integrated stress response by direct activation of GCN2 - Nature Communications
Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...
www.nature.com
November 17, 2025 at 12:12 PM
Reposted by Michael Way
I'm starting a petition to have the Irish Presidential Election rerun so we can have Troy Parrott on the ballot
November 16, 2025 at 4:06 PM
Reposted by Michael Way
Our story on GroEL/ES action during cotranslational folding is now published @natcomms.nature.com. Led by former-student Alzbeta Roeselova, and in collaboration with Rado Enchev's lab @crick.ac.uk.
www.nature.com/articles/s41...
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome - Nature Communications
The GroEL/ES chaperonin can act during protein synthesis to promote folding. Here, Roeselová et al. show how GroEL captures, remodels and sequesters nascent proteins in its central chamber, while they...
www.nature.com
November 14, 2025 at 1:49 PM
Reposted by Michael Way
We're still accepting submissions for our 'Cell Biology of the Nucleus' special issue, which is being guest edited by
@abbybuch.bsky.social and Megan King (@luskinglab.bsky.social).
Submission deadline: 5 January
journals.biologists.com/jcs/pages/nu...
#nucleus #notforprofit #freetopublish
November 13, 2025 at 5:13 PM
Reposted by Michael Way
We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast
cancer cells. www.biorxiv.org/content/10.1...

We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.
November 14, 2025 at 9:33 AM
Now for something completely different - Way lab does immunology - check out our @science.org paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors @luiz90vasc.bsky.social @shainahuang.bsky.social
November 14, 2025 at 9:16 AM
Reposted by Michael Way
Researchers at the Crick have discovered that mice lacking a specific gene responsible for cell structure lose intestinal balance and experience systemic inflammation, mirroring a lethal condition seen in humans.

www.crick.ac.uk/news/2025-11...
How weakness in cell structure affects the host-microbiome relationship
Mice lacking a gene responsible for cell structure lose intestinal balance and experience systemic inflammation, mirroring a lethal condition seen in humans.
www.crick.ac.uk
November 13, 2025 at 7:56 PM
Reposted by Michael Way
Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!
🚀 Exciting news! ERC Synergy Grant of €8.5 million to Sara Wickström @sarawickstrom.bsky.social, Daniel St Jonston @gurdoninstitute.bsky.social and Ewa Paluch @universitypress.cambridge.org! This highly interdisciplinary project will boost our understanding of tissue biology. #ERCSyG @erc.europa.eu
November 6, 2025 at 12:14 PM
Reposted by Michael Way
Post-doc position alert!

We will use #cryo-EM to decipher how a set of actin-binding proteins organises the #cytoskeleton, including during #cancer and #viral pathogenic processes.

#KCL has access to;
Krios + K3
cryoARM200 + K3
FIB-SEM
Cryo-CLEM

www.timeshighereducation.com/unijobs/list...
November 7, 2025 at 5:31 PM
Reposted by Michael Way
Personal good news alert: I’ve been promoted to associate professor and it’s time to update the ol’ bio! Launching my lab at UCSF has been a privilege + I’m so grateful to my team and community here. More exciting science ahead! 🚀
November 6, 2025 at 8:12 PM
Reposted by Michael Way
November 5, 2025 at 9:18 AM
Reposted by Michael Way
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella

journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
It's nice to see gallery proofs to see how the final accepted paper will look, but I do hate having to check the proofs!
October 29, 2025 at 4:46 PM
Reposted by Michael Way
Ready to start your own independent research programme?

We're inviting applications for early career group leaders in all areas of biology and biomedicine @crick.ac.uk

Apply by 27 Nov 2025:
www.crick.ac.uk/careers-stud...

#EarlyCareerResearchers #GroupLeader #ScienceCareers
October 9, 2025 at 3:01 PM
Reposted by Michael Way
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
Reposted by Michael Way
Explore emerging research with field leaders @keystoneSymposia.bsky.social #Autophagy : Mechanisms to Therapy, this February in Keystone! keysym.us/KSAutophagy26 #KSAutophagy26 www.keystonesymposia.org/conferences/...
Autophagy: Mechanisms to Therapy | Keystone Symposia
Join us at the Keystone Symposia on Autophagy: Mechanisms to Therapy, February 2026, in Keystone, with field leaders!
keysym.us
October 9, 2025 at 4:52 AM
Reposted by Michael Way
Love this
Video: a Japanese scientist was attacked by flies while giving the acceptance speech for his Ig Nobel Prize-winning research paper that proved painting Zebra-like stripes on cows led to a decrease in biting fly attacks.
October 4, 2025 at 9:15 PM
Reposted by Michael Way
I forgot that I had this made. As a prototype that never went into full production, it's the only one in existence and, therefore, highly desirable.

Let's start the bidding at £1,809, £1 for every day since the very first CBIAS.

For an extra 50%, you can have it signed by @martinjones.bsky.social.
October 3, 2025 at 7:48 AM
Reposted by Michael Way
Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme.

Apply by 05 November 2025

www.crick.ac.uk/careers-and-...
PhD students
Our PhD programme attracts the brightest scientific minds and is an opportunity for talented people to embark on their career in biomedical research.
www.crick.ac.uk
October 2, 2025 at 12:53 PM