Dr Laura McCulloch
@dr-l-mcculloch.bsky.social
Principal investigator at the University of Edinburgh.
Research on the systemic immune response to stroke and complications of stroke recovery. #Bcells #infection #GIdysfunction #cognitivedecline
Wellcome Sir Henry Dale fellow
Research on the systemic immune response to stroke and complications of stroke recovery. #Bcells #infection #GIdysfunction #cognitivedecline
Wellcome Sir Henry Dale fellow
We also found altered luminal IgG concentrations and reduced antibody coating of intestinal bacteria only at 3 months post stroke.
April 29, 2025 at 10:05 AM
We also found altered luminal IgG concentrations and reduced antibody coating of intestinal bacteria only at 3 months post stroke.
Changes to the composition of the microbiome were detected througout recovery. Surprisingly these changes were distinct at acute and chronic recovery time points suggesting different driving factors may be associated with these changes.
April 29, 2025 at 10:05 AM
Changes to the composition of the microbiome were detected througout recovery. Surprisingly these changes were distinct at acute and chronic recovery time points suggesting different driving factors may be associated with these changes.
At our earliest timepoint, 5 days post stroke, there is a reduced mucus barrier in the colon and a delayed intestinal transit time. However these normalise in chronic recovery
April 29, 2025 at 10:05 AM
At our earliest timepoint, 5 days post stroke, there is a reduced mucus barrier in the colon and a delayed intestinal transit time. However these normalise in chronic recovery
We found lower body weights and structural changes to the colon persisted out to 3 months after experimental stroke (MCAO) in mice
April 29, 2025 at 10:05 AM
We found lower body weights and structural changes to the colon persisted out to 3 months after experimental stroke (MCAO) in mice