doodle2000.bsky.social
@doodle2000.bsky.social
Reposted
Findings demonstrate that γ-tocotrienol offers superior protection against muscle atrophy compared to α-tocopherol, highlighting its therapeutic potential for individuals at risk of muscle wasting.
www.sciencedirect.com/science/arti...
September 19, 2025 at 7:32 AM
Reposted
Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social

rdcu.be/eMmcT
Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs
Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...
rdcu.be
October 24, 2025 at 4:20 PM
Reposted
• Cross-species comparison reveals links between lipoprotein metabolism & longevity
• High HDL & efficient cholesterol transport support longevity
• Molecular pathways AMPK, mTOR, SIRT integrate lipid metabolism with aging regulation
• CR & lipid-modifying therapies improve healthspan
November 3, 2025 at 7:35 AM
Reposted
Multi-omics profiling reveals that time-restricted feeding improves metabolic health in HFHFD-fed mice independent of weight loss by enhancing iWAT thermogenesis through mitochondrial OXPHOS, with specific upregulation of ETC complex I proteins.
www.sciencedirect.com/science/arti...
November 7, 2025 at 7:09 AM