Transposon and Cancer Epigenetics Group
@deniz-lab.bsky.social
Gene regulation, enhancer, 3D chromatin, transposable elements, cancer epigenetics, inflammation, leukaemia
Only 6 days left to apply! We’re recruiting a PhD student to study the immunogenic roles of transposable elements in pediatric AML. The project involves working with clinical trial samples in collaboration with Dr. Richard Dillon (KCL). If interested, get in touch!
Come and join us to discover immunogenic potential of transposable elements in pediatric AML as part of CRUK CoL PhD programme.
We're offering two fantastic #PhD projects in #paediatric cancers, to start Sept 2026. Browse all our projects and apply by noon, Weds 5 Nov: https://www.colcc.ac.uk/cyp-phd-studentships/ @qmbci.bsky.social @kingslsm.bsky.social @uclmedsci.bsky.social @crick.ac.uk #CRUKFunded
October 30, 2025 at 7:18 AM
Only 6 days left to apply! We’re recruiting a PhD student to study the immunogenic roles of transposable elements in pediatric AML. The project involves working with clinical trial samples in collaboration with Dr. Richard Dillon (KCL). If interested, get in touch!
Come and join us to discover immunogenic potential of transposable elements in pediatric AML as part of CRUK CoL PhD programme.
We're offering two fantastic #PhD projects in #paediatric cancers, to start Sept 2026. Browse all our projects and apply by noon, Weds 5 Nov: https://www.colcc.ac.uk/cyp-phd-studentships/ @qmbci.bsky.social @kingslsm.bsky.social @uclmedsci.bsky.social @crick.ac.uk #CRUKFunded
October 15, 2025 at 8:41 AM
Come and join us to discover immunogenic potential of transposable elements in pediatric AML as part of CRUK CoL PhD programme.
We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...
October 2, 2025 at 6:51 PM
We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...
Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant
hematopoiesis. www.cell.com/trends/cance...
hematopoiesis. www.cell.com/trends/cance...
Reawakening retrotransposons: immune modulation in normal and malignant hematopoiesis
Retrotransposons are mobile repetitive elements that constitute around 43% of the
human genome. Normally silenced through epigenetic mechanisms, retrotransposons can
become reactivated in response to ...
www.cell.com
September 3, 2025 at 5:02 AM
Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant
hematopoiesis. www.cell.com/trends/cance...
hematopoiesis. www.cell.com/trends/cance...
Reposted by Transposon and Cancer Epigenetics Group
🚨 New preprint alert 🚨
We systematically benchmarked @nanoporetech.com 's modification-aware basecalling models released for RNA on sets of in vitro and in vivo sequences and made some curious observations 🧬🔍.
bit.ly/4lXqNul
Follow along for a little recap (1/12)
We systematically benchmarked @nanoporetech.com 's modification-aware basecalling models released for RNA on sets of in vitro and in vivo sequences and made some curious observations 🧬🔍.
bit.ly/4lXqNul
Follow along for a little recap (1/12)
Systematic benchmarking of basecalling models for RNA modification detection with highly multiplexed nanopore sequencing
Nanopore direct RNA sequencing (DRS) holds promise for advancing our understanding of the epitranscriptome by detecting RNA modifications in native RNA molecules. Recently, Oxford Nanopore Technologie...
bit.ly
July 14, 2025 at 4:00 PM
🚨 New preprint alert 🚨
We systematically benchmarked @nanoporetech.com 's modification-aware basecalling models released for RNA on sets of in vitro and in vivo sequences and made some curious observations 🧬🔍.
bit.ly/4lXqNul
Follow along for a little recap (1/12)
We systematically benchmarked @nanoporetech.com 's modification-aware basecalling models released for RNA on sets of in vitro and in vivo sequences and made some curious observations 🧬🔍.
bit.ly/4lXqNul
Follow along for a little recap (1/12)
Reposted by Transposon and Cancer Epigenetics Group
Less than a month left until the Centre for Epigenetics Launch Conference! 🚀The scientific programme encompasses both oral and poster presentations by invited speakers and selected abstract submissions. There is still time to book your free ticket here: www.eventbrite.co.uk/e/qmul-centr...
QMUL Centre for Epigenetics Launch Conference 2025
Join us in celebrating becoming an official Centre for Epigenetics at QMUL!
www.eventbrite.co.uk
May 15, 2025 at 1:54 PM
Less than a month left until the Centre for Epigenetics Launch Conference! 🚀The scientific programme encompasses both oral and poster presentations by invited speakers and selected abstract submissions. There is still time to book your free ticket here: www.eventbrite.co.uk/e/qmul-centr...
I am excited to share our lab's first review out with in Blood Cancer Journal. We discuss the impact of transposable elements on genome regulation and variation in both normal
haematopoietic processes and haematological cancers. www.nature.com/articles/s41...
haematopoietic processes and haematological cancers. www.nature.com/articles/s41...
Transposable elements as genome regulators in normal and malignant haematopoiesis - Blood Cancer Journal
Blood Cancer Journal - Transposable elements as genome regulators in normal and malignant haematopoiesis
www.nature.com
May 6, 2025 at 4:31 PM
I am excited to share our lab's first review out with in Blood Cancer Journal. We discuss the impact of transposable elements on genome regulation and variation in both normal
haematopoietic processes and haematological cancers. www.nature.com/articles/s41...
haematopoietic processes and haematological cancers. www.nature.com/articles/s41...
This EHA meeting was a blast! Great to see so many of the leaders in the field and young minds!
March 25, 2025 at 7:59 PM
This EHA meeting was a blast! Great to see so many of the leaders in the field and young minds!
Reposted by Transposon and Cancer Epigenetics Group
We're excited to announce the official QMUL Centre for Epigenetics Launch Conference 2025! 🎉 To find out more and book your free ticket, please follow the link below:
www.eventbrite.co.uk/e/qmul-centr...
@qmul.ac.uk
@bartscharity.bsky.social
@qmulepigenetics.bsky.social
www.eventbrite.co.uk/e/qmul-centr...
@qmul.ac.uk
@bartscharity.bsky.social
@qmulepigenetics.bsky.social
QMUL Centre for Epigenetics Launch Conference 2025
Join us in celebrating becoming an official Centre for Epigenetics at QMUL!
www.eventbrite.co.uk
February 13, 2025 at 11:07 AM
We're excited to announce the official QMUL Centre for Epigenetics Launch Conference 2025! 🎉 To find out more and book your free ticket, please follow the link below:
www.eventbrite.co.uk/e/qmul-centr...
@qmul.ac.uk
@bartscharity.bsky.social
@qmulepigenetics.bsky.social
www.eventbrite.co.uk/e/qmul-centr...
@qmul.ac.uk
@bartscharity.bsky.social
@qmulepigenetics.bsky.social
Reposted by Transposon and Cancer Epigenetics Group
OPPORTUNITY TO JOIN US!
Two of these PhD positions are available in our group.
We want to know how nuclear metabolism impacts chromatin regulation in leukaemia.
You as well?
> Then check this out!
Two of these PhD positions are available in our group.
We want to know how nuclear metabolism impacts chromatin regulation in leukaemia.
You as well?
> Then check this out!
🚨 We’re hiring! 16 PhD opportunities in an emerging research field! 🚨
Are you ready to dive into innovative research in metabolic regulation of genome function in stem cells and cancer?
🔗 Learn more & apply now: nuclear-dn.eu
#PhDOpportunities #StemCellBiology #CancerResearch #MSCA
Please RP!
Are you ready to dive into innovative research in metabolic regulation of genome function in stem cells and cancer?
🔗 Learn more & apply now: nuclear-dn.eu
#PhDOpportunities #StemCellBiology #CancerResearch #MSCA
Please RP!
February 6, 2025 at 5:23 PM
OPPORTUNITY TO JOIN US!
Two of these PhD positions are available in our group.
We want to know how nuclear metabolism impacts chromatin regulation in leukaemia.
You as well?
> Then check this out!
Two of these PhD positions are available in our group.
We want to know how nuclear metabolism impacts chromatin regulation in leukaemia.
You as well?
> Then check this out!
Reposted by Transposon and Cancer Epigenetics Group
!THREE OPPORTUNITIES TO JOIN US!
We are looking for 3 (!!!) PhD students interested in:
How Metabolism affects Genome Regulation.
Join us at @carrerasijc.bsky.social as Marie Sklodowska Curie network fellow.
More info:
2 x experimental: www.nuclear-dn.eu
1 x computational: www.hubmol.eu
We are looking for 3 (!!!) PhD students interested in:
How Metabolism affects Genome Regulation.
Join us at @carrerasijc.bsky.social as Marie Sklodowska Curie network fellow.
More info:
2 x experimental: www.nuclear-dn.eu
1 x computational: www.hubmol.eu
February 12, 2025 at 3:34 PM
!THREE OPPORTUNITIES TO JOIN US!
We are looking for 3 (!!!) PhD students interested in:
How Metabolism affects Genome Regulation.
Join us at @carrerasijc.bsky.social as Marie Sklodowska Curie network fellow.
More info:
2 x experimental: www.nuclear-dn.eu
1 x computational: www.hubmol.eu
We are looking for 3 (!!!) PhD students interested in:
How Metabolism affects Genome Regulation.
Join us at @carrerasijc.bsky.social as Marie Sklodowska Curie network fellow.
More info:
2 x experimental: www.nuclear-dn.eu
1 x computational: www.hubmol.eu
Reposted by Transposon and Cancer Epigenetics Group
Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/
www.encodeproject.org/single-cell/...
www.encodeproject.org/single-cell/...
Single cell – ENCODEHomo sapiens clickable body map
www.encodeproject.org
January 7, 2025 at 9:29 PM
Very excited to announce that the single cell/nuc. RNA/ATAC/multi-ome resource from ENCODE4 is now officially public. This includes raw data, processed data, annotations and pseudobulk products. Covers many human & mouse tissues. 1/
www.encodeproject.org/single-cell/...
www.encodeproject.org/single-cell/...
Reposted by Transposon and Cancer Epigenetics Group
How does the ORF1p perform its multiple functions to facilitate LINE1 retrotransposition? And what enables its ability to also facilitate replication of other retrotransposons? Find out in our newly published paper in Nucleic Acids Research doi.org/10.1093/nar/...
L1-ORF1p nucleoprotein can rapidly assume distinct conformations and simultaneously bind more than one nucleic acid
Abstract. LINE-1 (L1) is a parasitic retrotransposable DNA element, active in primates for the last 80–120 Myr. L1 has generated nearly one-third of the hu
doi.org
December 23, 2024 at 2:57 AM
How does the ORF1p perform its multiple functions to facilitate LINE1 retrotransposition? And what enables its ability to also facilitate replication of other retrotransposons? Find out in our newly published paper in Nucleic Acids Research doi.org/10.1093/nar/...
Thrilled to announce the EHA Research Conference 2025!
Join us for a stellar line-up of talks on: ✨Transcriptional Control and Chromatin Alterations in Normal and Abnormal Hematopoiesis✨
🗓️ Abstract deadline: Jan 8, 2025
📌 Details & personalised flyer below—don’t miss it! ehaweb.org/meetings/eha...
Join us for a stellar line-up of talks on: ✨Transcriptional Control and Chromatin Alterations in Normal and Abnormal Hematopoiesis✨
🗓️ Abstract deadline: Jan 8, 2025
📌 Details & personalised flyer below—don’t miss it! ehaweb.org/meetings/eha...
December 8, 2024 at 4:56 PM
Thrilled to announce the EHA Research Conference 2025!
Join us for a stellar line-up of talks on: ✨Transcriptional Control and Chromatin Alterations in Normal and Abnormal Hematopoiesis✨
🗓️ Abstract deadline: Jan 8, 2025
📌 Details & personalised flyer below—don’t miss it! ehaweb.org/meetings/eha...
Join us for a stellar line-up of talks on: ✨Transcriptional Control and Chromatin Alterations in Normal and Abnormal Hematopoiesis✨
🗓️ Abstract deadline: Jan 8, 2025
📌 Details & personalised flyer below—don’t miss it! ehaweb.org/meetings/eha...
Looking forward to it!!
Registration now for the 2025 Cancer Genetics and Epigenetics GRC, a premier event for you to dive into groundbreaking research and network with leading experts in the field.
📅 Date: May 18-23, 2025
📍 Venue: Tuscany, Italy
🔗 Apply Now: www.grc.org/cancer-genet...
📅 Date: May 18-23, 2025
📍 Venue: Tuscany, Italy
🔗 Apply Now: www.grc.org/cancer-genet...
2025 Cancer Genetics and Epigenetics Conference GRC
The 2025 Gordon Research Conference on Cancer Genetics and Epigenetics will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
November 20, 2024 at 8:28 PM
Looking forward to it!!
Reposted by Transposon and Cancer Epigenetics Group
We are looking for a postdoctoral data scientist position to join our supportive and fun group :) Join us @QMBCI in vibrant #London to delve into the analysis of repetitive genome in #cancer! We support for visa applications, career and personal development! www.jobs.ac.uk/job/DFN649/p...
January 25, 2024 at 7:39 AM
We are looking for a postdoctoral data scientist position to join our supportive and fun group :) Join us @QMBCI in vibrant #London to delve into the analysis of repetitive genome in #cancer! We support for visa applications, career and personal development! www.jobs.ac.uk/job/DFN649/p...
Reposted by Transposon and Cancer Epigenetics Group
Postdoc position in Rakyan Lab! The position will focus on the molecular basis of differences in translational output amongst different ancestries in humans, combining proteomics, genomics and computational approaches. Please do email me for further info!
www.jobs.ac.uk/job/DFL087/p...
www.jobs.ac.uk/job/DFL087/p...
Post-Doctoral Research Assistant at Queen Mary University of London
An opportunity for an academic position as a Post-Doctoral Research Assistant is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
January 26, 2024 at 3:41 PM
Postdoc position in Rakyan Lab! The position will focus on the molecular basis of differences in translational output amongst different ancestries in humans, combining proteomics, genomics and computational approaches. Please do email me for further info!
www.jobs.ac.uk/job/DFL087/p...
www.jobs.ac.uk/job/DFL087/p...
We are looking for a postdoctoral data scientist to join our group in London, TEworldwide
We are looking for a postdoctoral data scientist position to join our supportive and fun group :) Join us @QMBCI in vibrant #London to delve into the analysis of repetitive genome in #cancer! We support for visa applications, career and personal development! www.jobs.ac.uk/job/DFN649/p...
January 25, 2024 at 9:54 AM
We are looking for a postdoctoral data scientist to join our group in London, TEworldwide
We are looking for a postdoctoral data scientist position to join our supportive and fun group :) Join us @QMBCI in vibrant #London to delve into the analysis of repetitive genome in #cancer! We support for visa applications, career and personal development! www.jobs.ac.uk/job/DFN649/p...
January 25, 2024 at 7:39 AM
We are looking for a postdoctoral data scientist position to join our supportive and fun group :) Join us @QMBCI in vibrant #London to delve into the analysis of repetitive genome in #cancer! We support for visa applications, career and personal development! www.jobs.ac.uk/job/DFN649/p...
Reposted by Transposon and Cancer Epigenetics Group
The non-coding repetitive genome as a source of regulatory DNA elements in cancer: a highlight of the recent work from
Biswajyoti Sahu: www.nature.com/articles/s41...
Biswajyoti Sahu: www.nature.com/articles/s41...
Enhanced transposable elements - Nature Reviews Cancer
Karttunen et al. identify the contribution of transposable elements to gene regulatory function in colorectal and liver cancer cell lines.
www.nature.com
October 25, 2023 at 1:52 PM
The non-coding repetitive genome as a source of regulatory DNA elements in cancer: a highlight of the recent work from
Biswajyoti Sahu: www.nature.com/articles/s41...
Biswajyoti Sahu: www.nature.com/articles/s41...