@davidweinshenker.bsky.social
Reposted
We’ll be hosting a free bicycle maintenance workshop soon that’s completely free. DM if you’d like to volunteer.
Marietta Bike Social: We ride every Saturday at 10AM, rain or shine, outside Marietta Square Market. Bring that fussy baby and let the sunshine and fresh air lull them into a good nap.
Marietta Bike Social: We ride every Saturday at 10AM, rain or shine, outside Marietta Square Market. Bring that fussy baby and let the sunshine and fresh air lull them into a good nap.
November 23, 2025 at 11:51 PM
We’ll be hosting a free bicycle maintenance workshop soon that’s completely free. DM if you’d like to volunteer.
Marietta Bike Social: We ride every Saturday at 10AM, rain or shine, outside Marietta Square Market. Bring that fussy baby and let the sunshine and fresh air lull them into a good nap.
Marietta Bike Social: We ride every Saturday at 10AM, rain or shine, outside Marietta Square Market. Bring that fussy baby and let the sunshine and fresh air lull them into a good nap.
Reposted
New pre-print led by the talented undergrad Alexia with @davidweinshenker.bsky.social
We used chronic DSP-4 treatment to lesion the LC-NE system in young TgF344-AD rats to see whether early degeneration led to accelerated onset of pathology and behavioral deficits.
www.biorxiv.org/content/10.1...
We used chronic DSP-4 treatment to lesion the LC-NE system in young TgF344-AD rats to see whether early degeneration led to accelerated onset of pathology and behavioral deficits.
www.biorxiv.org/content/10.1...
Impact of early locus coeruleus lesions in the TgF344 Alzheimer’s disease rat model
INTRODUCTION In murine models of Alzheimer’s disease (AD), lesioning the locus coeruleus-norepinephrine (LC-NE) system with DSP-4 exacerbates AD-like neuropathology and cognitive impairment. However, ...
www.biorxiv.org
November 15, 2025 at 7:04 PM
New pre-print led by the talented undergrad Alexia with @davidweinshenker.bsky.social
We used chronic DSP-4 treatment to lesion the LC-NE system in young TgF344-AD rats to see whether early degeneration led to accelerated onset of pathology and behavioral deficits.
www.biorxiv.org/content/10.1...
We used chronic DSP-4 treatment to lesion the LC-NE system in young TgF344-AD rats to see whether early degeneration led to accelerated onset of pathology and behavioral deficits.
www.biorxiv.org/content/10.1...
At #SFN2025 and interersted in the 🔵? Check out posters from Leslie Hassanein (D52; neuromelanin in the mouse locus coeruleus) and Maggie Tish (C59; human 3D locus coeruleus organoids) today from 1:00-5:00!
November 15, 2025 at 12:47 PM
At #SFN2025 and interersted in the 🔵? Check out posters from Leslie Hassanein (D52; neuromelanin in the mouse locus coeruleus) and Maggie Tish (C59; human 3D locus coeruleus organoids) today from 1:00-5:00!
Reposted
We’re hiring a technician!!
We’re an inclusive team of behavioral neuroscientists trying to discover the brain circuits of learning, decision making, and habit. More info👇
wassumlab.psych.ucla.edu/join-the-lab/
Job posting:
jobs.ucla.edu/jobs/8968
We’re an inclusive team of behavioral neuroscientists trying to discover the brain circuits of learning, decision making, and habit. More info👇
wassumlab.psych.ucla.edu/join-the-lab/
Job posting:
jobs.ucla.edu/jobs/8968
November 3, 2025 at 3:52 PM
We’re hiring a technician!!
We’re an inclusive team of behavioral neuroscientists trying to discover the brain circuits of learning, decision making, and habit. More info👇
wassumlab.psych.ucla.edu/join-the-lab/
Job posting:
jobs.ucla.edu/jobs/8968
We’re an inclusive team of behavioral neuroscientists trying to discover the brain circuits of learning, decision making, and habit. More info👇
wassumlab.psych.ucla.edu/join-the-lab/
Job posting:
jobs.ucla.edu/jobs/8968
Reposted
In this recent paper, maternal separation stress produced dysregulated noradrenergic activity in the locus coeruleus (LC) across the lifespan, which disrupted LC regulation of coping strategies in adulthood
Maternal separation disrupts noradrenergic control of adult coping behaviors
Neuropsychopharmacology - Maternal separation disrupts noradrenergic control of adult coping behaviors
www.nature.com
October 29, 2025 at 3:31 PM
In this recent paper, maternal separation stress produced dysregulated noradrenergic activity in the locus coeruleus (LC) across the lifespan, which disrupted LC regulation of coping strategies in adulthood
Reposted
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
October 31, 2025 at 5:24 PM
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Reposted
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
October 31, 2025 at 3:42 PM
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted
Finally, we made 2 web tools to share to this unprecedently large human LC xscriptomic data. A 3rd (that visualizes high-res H&E and NM with and spatial gene xpr.) on the way (last URL). We hope these help the #bluespot #LC #catecholamines community! Tools at: research.libd.org/LFF_spatial_... (7/8)
Impact of Alzheimer’s disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
LFF project, spatial_LC data analysis
research.libd.org
October 31, 2025 at 3:42 PM
Finally, we made 2 web tools to share to this unprecedently large human LC xscriptomic data. A 3rd (that visualizes high-res H&E and NM with and spatial gene xpr.) on the way (last URL). We hope these help the #bluespot #LC #catecholamines community! Tools at: research.libd.org/LFF_spatial_... (7/8)
Reposted
Noradrenergic Dysregulation in the Locus Coeruleus: Implications for Neuropsychiatric Disease Pathophysiology
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Noradrenergic Dysregulation in the Locus Coeruleus: Implications for Neuropsychiatric Disease Pathophysiology
The locus coeruleus [LC] is a dense cluster of noradrenergic neurons located in the dorsal pons of the brainstem and serves as the brain’s principal s…
www.sciencedirect.com
October 30, 2025 at 4:31 PM
Noradrenergic Dysregulation in the Locus Coeruleus: Implications for Neuropsychiatric Disease Pathophysiology
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted
ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline.
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
October 30, 2025 at 3:59 PM
ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline.
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Reposted
If you're heading to #SfN25 in a couple weeks, pop in early to the posters on Saturday afternoon and Sunday morning to see a bunch of cool unpublished work from the lab.
October 29, 2025 at 5:45 PM
If you're heading to #SfN25 in a couple weeks, pop in early to the posters on Saturday afternoon and Sunday morning to see a bunch of cool unpublished work from the lab.
Reposted
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience
recruiting.paylocity.com/recruiting/j...
recruiting.paylocity.com/recruiting/j...
Lieber Institute For Brain Development - Staff Scientist I, Translational Neuroscience
A little about us:The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with develop...
recruiting.paylocity.com
October 29, 2025 at 4:03 PM
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience
recruiting.paylocity.com/recruiting/j...
recruiting.paylocity.com/recruiting/j...
Reposted
You probably already know this, but today was the first full missed pay check for most of your friends, colleagues, POs and SROs at the NIH.
Stay strong out there folks. If you need help, ask for it. As always, try to be kind.
Stay strong out there folks. If you need help, ask for it. As always, try to be kind.
October 24, 2025 at 1:02 PM
You probably already know this, but today was the first full missed pay check for most of your friends, colleagues, POs and SROs at the NIH.
Stay strong out there folks. If you need help, ask for it. As always, try to be kind.
Stay strong out there folks. If you need help, ask for it. As always, try to be kind.
Reposted
In the amygdala, noradrenergic signaling in astrocytes could prime their response to nearby neurons that helps stabilize fear memories.
By @lauren-schneider.com
www.thetransmitter.org/memory/engra...
By @lauren-schneider.com
www.thetransmitter.org/memory/engra...
Engrams in amygdala lean on astrocytes to solidify memories
Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.
www.thetransmitter.org
October 22, 2025 at 9:23 PM
In the amygdala, noradrenergic signaling in astrocytes could prime their response to nearby neurons that helps stabilize fear memories.
By @lauren-schneider.com
www.thetransmitter.org/memory/engra...
By @lauren-schneider.com
www.thetransmitter.org/memory/engra...
Reposted
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:28 PM
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Reposted
Your donation is tax deductible and supports the young scientists who are being lost due to the federal funding crisis. #WCBR2026 nam12.safelinks.protection.outlook.com?url=https%3A...
October 22, 2025 at 5:29 PM
Your donation is tax deductible and supports the young scientists who are being lost due to the federal funding crisis. #WCBR2026 nam12.safelinks.protection.outlook.com?url=https%3A...
This is pretty cool www.nature.com/articles/s41...
Cocaine chemogenetics blunts drug-seeking by synthetic physiology - Nature
Cocaine chemogenetics in rats is a selective approach for countering drug reinforcement by clamping dopamine release in the presence of cocaine.
www.nature.com
October 16, 2025 at 1:39 PM
This is pretty cool www.nature.com/articles/s41...
Reposted
To good to be true?
Not this time!
Any questions—just ask!!
Not this time!
Any questions—just ask!!
🧠 THC researchers: Get free adolescent THC brain & organ tissue from UCI ICAL Tissue Bank! No DEA license needed, shipping covered. Limited supply—first-come, first-served! 🌱🔬
📩 DM for info
IG: @uci_cannabis | X: @ucicannabis
REQUEST HERE: cannabis.uci.edu/ical/tissueb...
#CannabisResearch #THC
📩 DM for info
IG: @uci_cannabis | X: @ucicannabis
REQUEST HERE: cannabis.uci.edu/ical/tissueb...
#CannabisResearch #THC
ICAL Tissue Bank - UCI Center for the Study of Cannabis
ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…
cannabis.uci.edu
October 13, 2025 at 9:20 AM
To good to be true?
Not this time!
Any questions—just ask!!
Not this time!
Any questions—just ask!!
Reposted
Assistant Professor opening in behavioral neuroscience at the University of Albany (SUNY). Join an outstanding department in one of the nation's greatest university systems.
#neurojobs
albany.interviewexchange.com/jobofferdeta...
#neurojobs
albany.interviewexchange.com/jobofferdeta...
albany.interviewexchange.com
October 10, 2025 at 12:02 PM
Assistant Professor opening in behavioral neuroscience at the University of Albany (SUNY). Join an outstanding department in one of the nation's greatest university systems.
#neurojobs
albany.interviewexchange.com/jobofferdeta...
#neurojobs
albany.interviewexchange.com/jobofferdeta...
Excited to share the Special Issue on "Stress and Addiction" in Addiction Neuroscience is now available. Huge kudos to guest editors Karl Schmidt and Anushree Karkhanis and all the authors who contributed. www.sciencedirect.com/special-issu...
Addiction Neuroscience | Stress <-> Addiction | ScienceDirect.com by Elsevier
Stress and drugs of abuse have a bidirectional relationship, such that stress is often seen as a driver of drug use, while at the same time drug use/abuse alters stress responses. Acute exposure to a ...
www.sciencedirect.com
October 9, 2025 at 1:22 PM
Excited to share the Special Issue on "Stress and Addiction" in Addiction Neuroscience is now available. Huge kudos to guest editors Karl Schmidt and Anushree Karkhanis and all the authors who contributed. www.sciencedirect.com/special-issu...
Reposted
Please spread the word! I am recruiting a PhD student this cycle (Fall 2026 start) to join my team in a new venture: the neuroscience of mood.
If you are curious to learn more, this short talk provides a good overview of why, what and how.
www.youtube.com/watch?v=gjIK...
If you are curious to learn more, this short talk provides a good overview of why, what and how.
www.youtube.com/watch?v=gjIK...
Nicole Rust - The representation of mood in the primate insula (May 6, 2025)
YouTube video by Simons Foundation
www.youtube.com
October 7, 2025 at 9:06 PM
Please spread the word! I am recruiting a PhD student this cycle (Fall 2026 start) to join my team in a new venture: the neuroscience of mood.
If you are curious to learn more, this short talk provides a good overview of why, what and how.
www.youtube.com/watch?v=gjIK...
If you are curious to learn more, this short talk provides a good overview of why, what and how.
www.youtube.com/watch?v=gjIK...
Reposted
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions
The brain constantly generates predictions based on one’s knowledge of the world,
as captured in memory. When these predictions are in error, our knowledge base must
be revised to remain relevant. Her...
www.cell.com
October 4, 2025 at 3:17 PM
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...
Reposted
Excited to announce that I'll be moving to the Univ of California Irvine @ucirvine.bsky.social next Spring!🌴
Happily, this is not goodbye to Japan as I'll continue my lab @RIKEN_CBS for some time.
Help spread the word: the new UCI lab will be hiring, DM or email ([email protected]) if interested!
Happily, this is not goodbye to Japan as I'll continue my lab @RIKEN_CBS for some time.
Help spread the word: the new UCI lab will be hiring, DM or email ([email protected]) if interested!
October 2, 2025 at 4:15 AM
Excited to announce that I'll be moving to the Univ of California Irvine @ucirvine.bsky.social next Spring!🌴
Happily, this is not goodbye to Japan as I'll continue my lab @RIKEN_CBS for some time.
Help spread the word: the new UCI lab will be hiring, DM or email ([email protected]) if interested!
Happily, this is not goodbye to Japan as I'll continue my lab @RIKEN_CBS for some time.
Help spread the word: the new UCI lab will be hiring, DM or email ([email protected]) if interested!
Reposted
Cool Postdoc opportunity alert! UNC SPIRE (Seeding Postdoctoral Innovators in Research & Education)-it provides scholars with both high quality research training & the opportunity to develop research based teaching skills that will inspire students across the sciences 1/n
spire.unc.edu/program-info/
spire.unc.edu/program-info/
October 1, 2025 at 2:31 PM
Cool Postdoc opportunity alert! UNC SPIRE (Seeding Postdoctoral Innovators in Research & Education)-it provides scholars with both high quality research training & the opportunity to develop research based teaching skills that will inspire students across the sciences 1/n
spire.unc.edu/program-info/
spire.unc.edu/program-info/
Reposted
Come be my colleague! Lots of exciting science, fantastic students and supportive colleagues. Emory University Biology Department tenure-track assistant professor position in neuroscience. share.google/945Jko4W1MTA.... Please feel free to retweet and share widely.
Emory University Biology Department tenure-track assistant professor position in neuroscience - Atlanta, Georgia job with [email protected] | 675335
Candidate uses experimental approaches to examine any aspect of neural function, including molecular, cellular, systems, or developmental neuroscience
share.google
September 29, 2025 at 7:34 PM
Come be my colleague! Lots of exciting science, fantastic students and supportive colleagues. Emory University Biology Department tenure-track assistant professor position in neuroscience. share.google/945Jko4W1MTA.... Please feel free to retweet and share widely.