CompBioPhys
@compbiophys.bsky.social
News and views from the research groups of H. Grubmüller, B. de Groot and A. Godec @MPI-NATGöttingen, Germany, Imprint: http://mpinat.mpg.de/en/imprint
👉 Steffen's preprint addressing "Bayesian #MINFLUX localization microscopy" is out @arxiv-soc-ph.bsky.social A rigorous #Bayesian approach should reduce the number of #photons required for 1 nm resolution by a factor of about 4️⃣! 🔗 doi.org/10.48550/arX... @mpi-nat.bsky.social @steschuu.bsky.social
November 14, 2025 at 8:52 AM
👉 Steffen's preprint addressing "Bayesian #MINFLUX localization microscopy" is out @arxiv-soc-ph.bsky.social A rigorous #Bayesian approach should reduce the number of #photons required for 1 nm resolution by a factor of about 4️⃣! 🔗 doi.org/10.48550/arX... @mpi-nat.bsky.social @steschuu.bsky.social
Possible #MD #projects are variational free energy methods, thermodynamics of #solvation shells, #constant-pH #MD methods, #Markovian thermodynamics, as well as functional mechanisms of the #ribosome, #FAS, #CRISPR/Cas, or #IDPs 🔗 #job 10-25 t1p.de/2e700 📩 E-mail to [email protected]
September 2, 2025 at 12:33 PM
Possible #MD #projects are variational free energy methods, thermodynamics of #solvation shells, #constant-pH #MD methods, #Markovian thermodynamics, as well as functional mechanisms of the #ribosome, #FAS, #CRISPR/Cas, or #IDPs 🔗 #job 10-25 t1p.de/2e700 📩 E-mail to [email protected]
👉 Open #PhD and #Postdoc positions in #computational #biophysics @mpi-nat.bsky.social in Göttingen 🇩🇪 in the Computational Biomolecular Dynamics group of Bert deGroot for several projects! Applications welcome! 🔗https://www.mpinat.mpg.de/5088717/24-25?c=645962 📝[email protected]
September 2, 2025 at 12:07 PM
👉 Open #PhD and #Postdoc positions in #computational #biophysics @mpi-nat.bsky.social in Göttingen 🇩🇪 in the Computational Biomolecular Dynamics group of Bert deGroot for several projects! Applications welcome! 🔗https://www.mpinat.mpg.de/5088717/24-25?c=645962 📝[email protected]
🎉 We are happy to have many of our dept members from @mpi-nat.bsky.social presenting their research projects at #EBSA2025 in Rome! Tomorrow's (July 1) poster session with Lisa (P-1.18) + Sara (P-1.186) and more to come... 😋 Wish you all an exciting #EBSA #biophysics #congress!!
June 30, 2025 at 12:57 PM
🎉 We are happy to have many of our dept members from @mpi-nat.bsky.social presenting their research projects at #EBSA2025 in Rome! Tomorrow's (July 1) poster session with Lisa (P-1.18) + Sara (P-1.186) and more to come... 😋 Wish you all an exciting #EBSA #biophysics #congress!!
😍 Lisa's sketch illustrates her passion for #GPCRs: Don't miss her most recent @chemicalscience.rsc.org 📜 publication about "Identification of allosteric sites and ligand-induced modulation in the dopamine receptor through large-scale alchemical mutation scan"🔗 doi.org/10.1039/D4SC... #compchem
June 18, 2025 at 2:57 PM
😍 Lisa's sketch illustrates her passion for #GPCRs: Don't miss her most recent @chemicalscience.rsc.org 📜 publication about "Identification of allosteric sites and ligand-induced modulation in the dopamine receptor through large-scale alchemical mutation scan"🔗 doi.org/10.1039/D4SC... #compchem
Wir freuen uns auf Euch bei der #ndwgoe nächsten Samstag! Trefft uns an Stand #14 am @mpsgoettingen.bsky.social auf Ebene 1 zu Computersimulationen von spannenden "Molekularen Maschinen", an denen man auch zupfen kann oder bastelt Euch eines zum Mitnehmen... @mpi-nat.bsky.social We love proteins! ❤️
June 16, 2025 at 1:04 PM
Wir freuen uns auf Euch bei der #ndwgoe nächsten Samstag! Trefft uns an Stand #14 am @mpsgoettingen.bsky.social auf Ebene 1 zu Computersimulationen von spannenden "Molekularen Maschinen", an denen man auch zupfen kann oder bastelt Euch eines zum Mitnehmen... @mpi-nat.bsky.social We love proteins! ❤️
⁉️ How is time #irreversibility connected to #thermodynamic #entropy production in systems observed at coarse resolution? 👉 For a mini- #review on the latest developments in this field, check out our recent #Perspective 📝article in The Journal of Chemical Physics
doi.org/10.1063/5.0251089
doi.org/10.1063/5.0251089
May 27, 2025 at 7:12 AM
⁉️ How is time #irreversibility connected to #thermodynamic #entropy production in systems observed at coarse resolution? 👉 For a mini- #review on the latest developments in this field, check out our recent #Perspective 📝article in The Journal of Chemical Physics
doi.org/10.1063/5.0251089
doi.org/10.1063/5.0251089
Starting from stochastic #equations of motion, we derived thermodynamic bounds on general transport observables. Our results feature 😲surprising practical #advantages, even allowing to address #observables from bulk exp. 📜 out in @physrevlett.bsky.social 🔗 doi.org/10.1103/PhysRevLett.133.067101
May 27, 2025 at 7:01 AM
Starting from stochastic #equations of motion, we derived thermodynamic bounds on general transport observables. Our results feature 😲surprising practical #advantages, even allowing to address #observables from bulk exp. 📜 out in @physrevlett.bsky.social 🔗 doi.org/10.1103/PhysRevLett.133.067101
📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in the Department of Theoretical and Computational #Biophysics in Göttingen! 🔗 Please check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. We are looking forward to receiving your application! 🤩
April 1, 2025 at 1:54 PM
📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in the Department of Theoretical and Computational #Biophysics in Göttingen! 🔗 Please check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. We are looking forward to receiving your application! 🤩
💭 Would you like to contribute to projects in the field of "Theory and Methods for Non-equilibrium #Theory and Atomistic Simulations of Complex# Biomolecules"? Join our department as #PhD student or #Postdoc at @mpi-nat.bsky.social in 🇩🇪 🔗 Here are more details www.mpinat.mpg.de/4965656/10-2... #job
April 1, 2025 at 1:11 PM
💭 Would you like to contribute to projects in the field of "Theory and Methods for Non-equilibrium #Theory and Atomistic Simulations of Complex# Biomolecules"? Join our department as #PhD student or #Postdoc at @mpi-nat.bsky.social in 🇩🇪 🔗 Here are more details www.mpinat.mpg.de/4965656/10-2... #job
🧐 Are you a computational physicist and expert in probability theory? 👉 Contribute to our project "Theory and Algorithms for Structure Determination from Single Molecule X-Ray Scattering Images" as PhD student or Postdoc! 🔗 Check our job advert for more details www.mpinat.mpg.de/4988122/09-2...
April 1, 2025 at 1:01 PM
🧐 Are you a computational physicist and expert in probability theory? 👉 Contribute to our project "Theory and Algorithms for Structure Determination from Single Molecule X-Ray Scattering Images" as PhD student or Postdoc! 🔗 Check our job advert for more details www.mpinat.mpg.de/4988122/09-2...
🥰 Many thanks to all participants for their contributions to this year's #Hünfeld2025 #TheoryWorkshop! We enjoyed excellent talks, great posters and exciting discussions about outstanding research projects! 👍 See you all back again next year on 📅 April 25-26, 2026
March 10, 2025 at 11:05 AM
🥰 Many thanks to all participants for their contributions to this year's #Hünfeld2025 #TheoryWorkshop! We enjoyed excellent talks, great posters and exciting discussions about outstanding research projects! 👍 See you all back again next year on 📅 April 25-26, 2026
🥹 Last day at #bps2025 and a 🤩 final poster session with contributions from our group @compbiophys.bsky.social @mpi-nat.bsky.social: Meet Annke, Lars @larsvbock.bsky.social and Malte during today's session 10:30 AM -12:30 PM and discuss their exciting projects with them before you say goodbye...👋
February 19, 2025 at 7:52 AM
🥹 Last day at #bps2025 and a 🤩 final poster session with contributions from our group @compbiophys.bsky.social @mpi-nat.bsky.social: Meet Annke, Lars @larsvbock.bsky.social and Malte during today's session 10:30 AM -12:30 PM and discuss their exciting projects with them before you say goodbye...👋
🤩 Highly optimized software running on a SOA #HPC cluster provides sufficient #computing power to #simulate #biomolecular systems at the mesoscale of viruses and organelles, and potentially small cells in the near future... Want to know more? Check out our paper 📑 in #JCC 🔗 doi.org/10.1002/jcc....
February 18, 2025 at 1:34 PM
🤩 Highly optimized software running on a SOA #HPC cluster provides sufficient #computing power to #simulate #biomolecular systems at the mesoscale of viruses and organelles, and potentially small cells in the near future... Want to know more? Check out our paper 📑 in #JCC 🔗 doi.org/10.1002/jcc....
Don't miss to see today's and tomorrow's posters #bps2025 from our group @compbiophys.bsky.social during the afternoon session 1:45-3:45 in the West Exhibit Hall! 🧐
February 17, 2025 at 8:05 AM
Don't miss to see today's and tomorrow's posters #bps2025 from our group @compbiophys.bsky.social during the afternoon session 1:45-3:45 in the West Exhibit Hall! 🧐
Poster Session #bps2025 on Sunday, February 16 starting at 1:45 pm in the West Exhibit Hall including posters of Aaron, Sara @saragabrielli.bsky.social, Ole, Bartosz, Chen, Reinier
plan.core-apps.com/bpsam2025/ev...
plan.core-apps.com/bpsam2025/ev...
February 14, 2025 at 2:09 PM
Poster Session #bps2025 on Sunday, February 16 starting at 1:45 pm in the West Exhibit Hall including posters of Aaron, Sara @saragabrielli.bsky.social, Ole, Bartosz, Chen, Reinier
plan.core-apps.com/bpsam2025/ev...
plan.core-apps.com/bpsam2025/ev...
We proudly present a selection of research projects from @compbiophys.bsky.social at this year's #bps2025 meeting in LA! Don't miss the oral presentations or posters being presented and find us in the program biophysics.cld.bz/BPS2025-Full...
February 14, 2025 at 2:09 PM
We proudly present a selection of research projects from @compbiophys.bsky.social at this year's #bps2025 meeting in LA! Don't miss the oral presentations or posters being presented and find us in the program biophysics.cld.bz/BPS2025-Full...
We are looking forward to meeting all participants online or on-site in Hünfeld very soon! 🤩 The program is now online: www.mpinat.mpg.de/workshop/hue.... For those who were not able to join this year... next workshop is scheduled for 📅 April 24-25, 2026! #Hünfeld2025 #TheoryWorkshop
February 13, 2025 at 1:28 PM
We are looking forward to meeting all participants online or on-site in Hünfeld very soon! 🤩 The program is now online: www.mpinat.mpg.de/workshop/hue.... For those who were not able to join this year... next workshop is scheduled for 📅 April 24-25, 2026! #Hünfeld2025 #TheoryWorkshop
📢 Our new paper in #SciAdv on #Bayesian electron density determination from single-molecule #X-ray scattering is out! 🧐 High resolutions can be achieved from #XFEL exp at low S/N ratios using less than 50 #photons per image! 🔗https://www.science.org/doi/10.1126/sciadv.adp4425 @mpi-nat.bsky.social
January 10, 2025 at 12:10 PM
📢 It's our great pleasure to invite you all to our upcoming #Workshop on "Computer Simulation and #Theory of Macromolecules" in #Hünfeld on March 7-8, 2025 in #hybrid format! See you online or on-site! More details are provided here: www.mpinat.mpg.de/workshop/hue... #TheoryHünfeld2025 #biophysics
December 4, 2024 at 1:43 PM
📢 It's our great pleasure to invite you all to our upcoming #Workshop on "Computer Simulation and #Theory of Macromolecules" in #Hünfeld on March 7-8, 2025 in #hybrid format! See you online or on-site! More details are provided here: www.mpinat.mpg.de/workshop/hue... #TheoryHünfeld2025 #biophysics
We have a #Job opening for a #PhD student in our group
here @mpi-nat.bsky.social in Göttingen 🇩🇪 in connection to #RTG2756 #CYTAC Job advert 🔗https://mpinat.mpg.de/4793823/28-24?c=645962 🔗https://uni-goettingen.de/rtg2756 #mircotubules #Applications welcome!
here @mpi-nat.bsky.social in Göttingen 🇩🇪 in connection to #RTG2756 #CYTAC Job advert 🔗https://mpinat.mpg.de/4793823/28-24?c=645962 🔗https://uni-goettingen.de/rtg2756 #mircotubules #Applications welcome!
November 25, 2024 at 10:29 AM
We have a #Job opening for a #PhD student in our group
here @mpi-nat.bsky.social in Göttingen 🇩🇪 in connection to #RTG2756 #CYTAC Job advert 🔗https://mpinat.mpg.de/4793823/28-24?c=645962 🔗https://uni-goettingen.de/rtg2756 #mircotubules #Applications welcome!
here @mpi-nat.bsky.social in Göttingen 🇩🇪 in connection to #RTG2756 #CYTAC Job advert 🔗https://mpinat.mpg.de/4793823/28-24?c=645962 🔗https://uni-goettingen.de/rtg2756 #mircotubules #Applications welcome!