Center for Cancer Immunotherapy and Immunobiology
@ccii-kyoto.bsky.social
Conquering cancer by advancing immunotherapy.
The CCII is a research center at Kyoto University, led by Nobel Laureate Prof Tasuku Honjo.
https://www.ccii.med.kyoto-u.ac.jp/en/
The CCII is a research center at Kyoto University, led by Nobel Laureate Prof Tasuku Honjo.
https://www.ccii.med.kyoto-u.ac.jp/en/
CCII Vice Director Sidonia Fagarasan introducing Michael Dustin (Oxford), who gave a great talk on the immunological synapse.
For a list of upcoming seminars & events at CCII, visit our webpage.
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
For a list of upcoming seminars & events at CCII, visit our webpage.
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
November 11, 2025 at 9:13 AM
CCII Vice Director Sidonia Fagarasan introducing Michael Dustin (Oxford), who gave a great talk on the immunological synapse.
For a list of upcoming seminars & events at CCII, visit our webpage.
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
For a list of upcoming seminars & events at CCII, visit our webpage.
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
The conference was held in Basel & Sidonia also took the opportunity to pay homage to Fritz Melchers, former Director of the Basel Institute of Immunology.
The BII has closed, but you can read about it in this 1997 @currentbiology.bsky.social piece 👇
www.cell.com/current-biol...
The BII has closed, but you can read about it in this 1997 @currentbiology.bsky.social piece 👇
www.cell.com/current-biol...
September 4, 2025 at 12:35 AM
The conference was held in Basel & Sidonia also took the opportunity to pay homage to Fritz Melchers, former Director of the Basel Institute of Immunology.
The BII has closed, but you can read about it in this 1997 @currentbiology.bsky.social piece 👇
www.cell.com/current-biol...
The BII has closed, but you can read about it in this 1997 @currentbiology.bsky.social piece 👇
www.cell.com/current-biol...
CCII's Sidonia Fagarasan presenting on "The intersection of adaptive & innate immunity in the lung: implications for chronic pulmonary insufficiency" at the @embo.org workshop on Adaptive Immunity at Barrier Tissues organized by @immunologyking.bsky.social @maurogaya.bsky.social
#EMBObarrierTissues
#EMBObarrierTissues
September 3, 2025 at 11:02 PM
CCII's Sidonia Fagarasan presenting on "The intersection of adaptive & innate immunity in the lung: implications for chronic pulmonary insufficiency" at the @embo.org workshop on Adaptive Immunity at Barrier Tissues organized by @immunologyking.bsky.social @maurogaya.bsky.social
#EMBObarrierTissues
#EMBObarrierTissues
To find out more about research in the Hagiwara group at CCII, click on 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
August 22, 2025 at 1:04 AM
To find out more about research in the Hagiwara group at CCII, click on 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
To find out more about research in the Hagiwara group at CCII, click on 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
August 22, 2025 at 1:01 AM
To find out more about research in the Hagiwara group at CCII, click on 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
Sidonia Fagarasan introducing CCII seminar speaker Hiroshi Ichise (University of Osaka). He presented advances in 3D imaging & what new biology it can help reveal, including a new immune cluster organized around the vagal nerves in the lung
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
August 20, 2025 at 12:04 AM
Sidonia Fagarasan introducing CCII seminar speaker Hiroshi Ichise (University of Osaka). He presented advances in 3D imaging & what new biology it can help reveal, including a new immune cluster organized around the vagal nerves in the lung
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
Tomorrow (Tuesday) at CCII, Hiroshi Ichise on
“Highly multiplex volumetric imaging Ce3D-IBEX reveals commensal-induced immune clustering along sensory nerves in the lung”
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/
“Highly multiplex volumetric imaging Ce3D-IBEX reveals commensal-induced immune clustering along sensory nerves in the lung”
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/
August 18, 2025 at 2:05 AM
Tomorrow (Tuesday) at CCII, Hiroshi Ichise on
“Highly multiplex volumetric imaging Ce3D-IBEX reveals commensal-induced immune clustering along sensory nerves in the lung”
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/
“Highly multiplex volumetric imaging Ce3D-IBEX reveals commensal-induced immune clustering along sensory nerves in the lung”
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/
Vice director Sidonia Fagarasan introducing Jianguo (Jeff) Xia from McGill University, who gave a seminar on "Leveraging #metabolomics and biological networks for functional insights into microbiome” this week at CCII.
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
July 24, 2025 at 9:07 AM
Vice director Sidonia Fagarasan introducing Jianguo (Jeff) Xia from McGill University, who gave a seminar on "Leveraging #metabolomics and biological networks for functional insights into microbiome” this week at CCII.
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
www.ccii.med.kyoto-u.ac.jp/en/event/eve...
At @ccii-kyoto.bsky.social Dr Nishikawa heads the Division of Cancer Immune Multicellular System Regulation
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
July 21, 2025 at 9:00 AM
At @ccii-kyoto.bsky.social Dr Nishikawa heads the Division of Cancer Immune Multicellular System Regulation
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
The Fagarasan Lab at CCII studies higher order regulation of immune responses, including the effects of metabolism and the nervous system in anti-tumor immunity
#Immunology #Immunotherapy #Metabolism
www.ccii.med.kyoto-u.ac.jp/en/research/...
#Immunology #Immunotherapy #Metabolism
www.ccii.med.kyoto-u.ac.jp/en/research/...
July 17, 2025 at 7:26 AM
The Fagarasan Lab at CCII studies higher order regulation of immune responses, including the effects of metabolism and the nervous system in anti-tumor immunity
#Immunology #Immunotherapy #Metabolism
www.ccii.med.kyoto-u.ac.jp/en/research/...
#Immunology #Immunotherapy #Metabolism
www.ccii.med.kyoto-u.ac.jp/en/research/...
CCII's Vice Director, Sidonia Fagarasan, and the faculty of this year's RIKEN IMS-JSI Summer School & Symposium.
Sidonia spoke about the biochemical dialog between immune cells mediating anti-cancer responses
www.ims.riken.jp/events/rcais...
Sidonia spoke about the biochemical dialog between immune cells mediating anti-cancer responses
www.ims.riken.jp/events/rcais...
July 17, 2025 at 7:22 AM
CCII's Vice Director, Sidonia Fagarasan, and the faculty of this year's RIKEN IMS-JSI Summer School & Symposium.
Sidonia spoke about the biochemical dialog between immune cells mediating anti-cancer responses
www.ims.riken.jp/events/rcais...
Sidonia spoke about the biochemical dialog between immune cells mediating anti-cancer responses
www.ims.riken.jp/events/rcais...
Ian Watson @ianwatsonlab.bsky.social from McGill University visited CCII this month & gave a seminar entitled "The NF1 tumor suppressor regulates PD-L1 & immune evasion in #melanoma"
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
July 15, 2025 at 4:10 PM
Ian Watson @ianwatsonlab.bsky.social from McGill University visited CCII this month & gave a seminar entitled "The NF1 tumor suppressor regulates PD-L1 & immune evasion in #melanoma"
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
#Immunology #Immunotherapy
www.ccii.med.kyoto-u.ac.jp/en/events/
Oslo University's Johanne Tracey Jacobsen visited CCII this week & shared exciting progress in the application of cutting edge imaging techniques to decode dynamic T-B interactions in the Germinal Center.
#Immunology #GerminalCenter
www.jjacobsenlab.com
#Immunology #GerminalCenter
www.jjacobsenlab.com
July 4, 2025 at 2:50 AM
Oslo University's Johanne Tracey Jacobsen visited CCII this week & shared exciting progress in the application of cutting edge imaging techniques to decode dynamic T-B interactions in the Germinal Center.
#Immunology #GerminalCenter
www.jjacobsenlab.com
#Immunology #GerminalCenter
www.jjacobsenlab.com
Day 3: Carolina Lucas (Yale) @carolilucas.bsky.social discussing with students and postdocs how her research in immunity to viruses (especially emerging pathogens) shifted from mouse to human systems & the surprises along the way.
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/events/
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/events/
July 2, 2025 at 11:38 PM
Day 3: Carolina Lucas (Yale) @carolilucas.bsky.social discussing with students and postdocs how her research in immunity to viruses (especially emerging pathogens) shifted from mouse to human systems & the surprises along the way.
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/events/
#Immunology
www.ccii.med.kyoto-u.ac.jp/en/events/
Victora, first author William DeWitt, and coll. asked an immunological version of SJ Gould's question: what would evolution look like if you replayed the tape?
(In this case, multiple iterations of clonal evolution in GCs)
(In this case, multiple iterations of clonal evolution in GCs)
July 2, 2025 at 2:47 AM
Victora, first author William DeWitt, and coll. asked an immunological version of SJ Gould's question: what would evolution look like if you replayed the tape?
(In this case, multiple iterations of clonal evolution in GCs)
(In this case, multiple iterations of clonal evolution in GCs)
Germinal center clonal diversity trees as a musical score, a great image to start @victora.bsky.social's CCII seminar, "Replaying germinal center evolution on a quantified affinity landscape"
#GerminalCenter #Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/the...
#GerminalCenter #Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/the...
July 2, 2025 at 2:42 AM
Germinal center clonal diversity trees as a musical score, a great image to start @victora.bsky.social's CCII seminar, "Replaying germinal center evolution on a quantified affinity landscape"
#GerminalCenter #Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/the...
#GerminalCenter #Immunology
www.ccii.med.kyoto-u.ac.jp/en/event/the...
Following Daniel @danmucida.bsky.social's session, Angelina Bilate @rockefelleruniv.bsky.social discussed strategies to identify antigen specific T cells.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
July 1, 2025 at 9:48 PM
Following Daniel @danmucida.bsky.social's session, Angelina Bilate @rockefelleruniv.bsky.social discussed strategies to identify antigen specific T cells.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Day 2. Gabriel Victora @victora.bsky.social discussing with students and postdocs the long & winding road to developing LIPSTIC, the tool his lab created to track cell-cell interactions in vivo
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 1, 2025 at 9:44 PM
Day 2. Gabriel Victora @victora.bsky.social discussing with students and postdocs the long & winding road to developing LIPSTIC, the tool his lab created to track cell-cell interactions in vivo
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prof @danmucida.bsky.social of @rockefelleruniv.bsky.social kicks off CCII's workshop on experimental design — with a focus on what to when things *dont* go to plan.
www.ccii.med.kyoto-u.ac.jp/en/event/wor...
www.ccii.med.kyoto-u.ac.jp/en/event/wor...
July 1, 2025 at 1:16 AM
Prof @danmucida.bsky.social of @rockefelleruniv.bsky.social kicks off CCII's workshop on experimental design — with a focus on what to when things *dont* go to plan.
www.ccii.med.kyoto-u.ac.jp/en/event/wor...
www.ccii.med.kyoto-u.ac.jp/en/event/wor...
These are five-year positions, renewable for an additional 3 years (following an evaluation stage) and include a salary of 8.5 million yen/year and a research budget of 20 million yen/year.
www.ccii.med.kyoto-u.ac.jp/en/careers-e...
www.ccii.med.kyoto-u.ac.jp/en/careers-e...
July 1, 2025 at 1:13 AM
These are five-year positions, renewable for an additional 3 years (following an evaluation stage) and include a salary of 8.5 million yen/year and a research budget of 20 million yen/year.
www.ccii.med.kyoto-u.ac.jp/en/careers-e...
www.ccii.med.kyoto-u.ac.jp/en/careers-e...
CCII researcher Sidonia Fagarasan presented recent progress in #metabolism & #immunity in Taiwan, at the Formosa #Immunology Spring School & Symposium 2025
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
May 30, 2025 at 5:12 AM
CCII researcher Sidonia Fagarasan presented recent progress in #metabolism & #immunity in Taiwan, at the Formosa #Immunology Spring School & Symposium 2025
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
PD-1 is a great example of the value of basic research:
Honjo & his then student Yasumasa Ishida were originally screening for molecules involved in apoptosis during T cell development in the thymus (hence the name).
Ishida et al @embojournal.org 1991 👇
www.embopress.org/doi/abs/10.1...
Honjo & his then student Yasumasa Ishida were originally screening for molecules involved in apoptosis during T cell development in the thymus (hence the name).
Ishida et al @embojournal.org 1991 👇
www.embopress.org/doi/abs/10.1...
May 28, 2025 at 2:15 PM
PD-1 is a great example of the value of basic research:
Honjo & his then student Yasumasa Ishida were originally screening for molecules involved in apoptosis during T cell development in the thymus (hence the name).
Ishida et al @embojournal.org 1991 👇
www.embopress.org/doi/abs/10.1...
Honjo & his then student Yasumasa Ishida were originally screening for molecules involved in apoptosis during T cell development in the thymus (hence the name).
Ishida et al @embojournal.org 1991 👇
www.embopress.org/doi/abs/10.1...
You can also hear the #PD1 story as told by CCII Director Tasuku Honjo on the @embo.org podcast
www.embo.org/podcasts/fro...
www.embo.org/podcasts/fro...
May 28, 2025 at 2:07 PM
You can also hear the #PD1 story as told by CCII Director Tasuku Honjo on the @embo.org podcast
www.embo.org/podcasts/fro...
www.embo.org/podcasts/fro...
CCII students & postdocs benefit from courses and workshops on a variety of topics, like this Peer Review workshop with visiting professor & former scientific editor Thiago Carvalho.
www.ccii.med.kyoto-u.ac.jp/en/
www.ccii.med.kyoto-u.ac.jp/en/
May 28, 2025 at 2:01 PM
CCII students & postdocs benefit from courses and workshops on a variety of topics, like this Peer Review workshop with visiting professor & former scientific editor Thiago Carvalho.
www.ccii.med.kyoto-u.ac.jp/en/
www.ccii.med.kyoto-u.ac.jp/en/
The Tsukamoto lab at CCII focuses on the adverse effects of immunotherapy — many of which are severe and can lead to treatment interruption. Find out more about their research here 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...
May 27, 2025 at 5:34 AM
The Tsukamoto lab at CCII focuses on the adverse effects of immunotherapy — many of which are severe and can lead to treatment interruption. Find out more about their research here 👇
www.ccii.med.kyoto-u.ac.jp/en/research/...
www.ccii.med.kyoto-u.ac.jp/en/research/...