Bryce Manso, Ph.D.
@brycemanso.bsky.social
IRACDA- and T32-funded postdoc in the Forsberg Lab at UCSC. I love all things Blood, Stem Cell, Hematopoiesis, and Immunology! Opinions are my own.
We have packed a ton into this paper, so please enjoy and reach out with any questions!
A HUGE thank you to all the collaborators and funding sources for making this happen!
A HUGE thank you to all the collaborators and funding sources for making this happen!
October 1, 2025 at 7:13 PM
We have packed a ton into this paper, so please enjoy and reach out with any questions!
A HUGE thank you to all the collaborators and funding sources for making this happen!
A HUGE thank you to all the collaborators and funding sources for making this happen!
We also demonstrate that both intrinsic and extrinsic effects contribute to informating HSCs to take this pathway, and that MkPs generated via this path uniquely possess a survival advantage!
October 1, 2025 at 7:13 PM
We also demonstrate that both intrinsic and extrinsic effects contribute to informating HSCs to take this pathway, and that MkPs generated via this path uniquely possess a survival advantage!
Here, we add to and clarify a number of new findings in the world of #megakaryopoiesis at steady-state and during aging, including officially revealing the ability to identify HSC-direct, age-dependent MkPs without the need of a lineage tracing model!
October 1, 2025 at 7:13 PM
Here, we add to and clarify a number of new findings in the world of #megakaryopoiesis at steady-state and during aging, including officially revealing the ability to identify HSC-direct, age-dependent MkPs without the need of a lineage tracing model!
Reposted by Bryce Manso, Ph.D.
#Pubmed problem fix?
Resetting DNS to Cloudfare 1.1.1.1 worked
I could use Pubmed on phone but not computer, but fixed Mac by:
settings > network > details > DNS > press “+” and type 1.1.1.1
🎉
Resetting DNS to Cloudfare 1.1.1.1 worked
I could use Pubmed on phone but not computer, but fixed Mac by:
settings > network > details > DNS > press “+” and type 1.1.1.1
🎉
#Pubmed problems being reported
Please say if it’s working for you, your country and search engine
(perhaps retweet for larger sample size
🤷♂️ fine for me, UK & Safari
Please say if it’s working for you, your country and search engine
(perhaps retweet for larger sample size
🤷♂️ fine for me, UK & Safari
March 2, 2025 at 3:11 PM
Full link to the text:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A rare HSC-derived megakaryocyte progenitor accumulates via enhanced survival and contributes to exacerbated thrombopoiesis upon aging
Distinct routes of cellular production from hematopoietic stem cells (HSCs) have defined our current view of hematopoiesis. Recently, we challenged classical views of platelet generation, demonstratin...
www.biorxiv.org
December 13, 2024 at 6:47 PM
Full link to the text:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
(7/7)...Finally, environment may be the "missing link" to this age-unique pathway, but more on that soon......
Please do give it a read and let us know what you think! We are excited to share this story!
Please do give it a read and let us know what you think! We are excited to share this story!
December 4, 2024 at 8:19 PM
(7/7)...Finally, environment may be the "missing link" to this age-unique pathway, but more on that soon......
Please do give it a read and let us know what you think! We are excited to share this story!
Please do give it a read and let us know what you think! We are excited to share this story!