Bruce Levine, Ph.D. 🇺🇦
@bllphd.bsky.social
🧬🧪Professor @Pennmedicine #CellTherapy #Genetherapy #Inventor #Kymriah #CARTCell @TmunityTx & @CapstanTx CoFounder, Past President @ISCTGlobal @PNASNexus AE
https://orcid.org/0000-0001-6971-8465
https://orcid.org/0000-0001-6971-8465
Pinned
Announcing the website for the song Ring That Bell 🔔 cowritten w @magsmccarthy.bsky.social an emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope. #cancer #cancerresearch #immunotherapy #hope ringthatbellsong.com
🚨Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain! 2025 laureates of the Broermann Medical Innovation Award for the development of the CAR-T cell #immunotherapy #cancer #CancerResearch pressreleasehub.pa.media/article/dr-c...
DR. CARL JUNE AND DR. MICHEL SADELAIN ARE BEING AWARDED THE BROERMANN MEDICAL INNOVATION AWARD 2025
Giessen (ots) - - With prize money of one million euros, it is one of the most highly endowed medical awards in the world
pressreleasehub.pa.media
September 18, 2025 at 11:34 AM
🚨Congratulations to Prof. Dr. Carl June & Prof. Dr. Michel Sadelain! 2025 laureates of the Broermann Medical Innovation Award for the development of the CAR-T cell #immunotherapy #cancer #CancerResearch pressreleasehub.pa.media/article/dr-c...
Is Germline Editing Feasible and Should it be Permissible? I joined @urnov.bsky.social, @kiranmusunuru.bsky.social, ISCT President Miguel Forte & Chief Regulatory Officer Bambi Grilley to discuss #ethics #bioethics & technological hurdles of embryo editing www.isctglobal.org/telegrafthub...
September 16, 2025 at 1:32 PM
Is Germline Editing Feasible and Should it be Permissible? I joined @urnov.bsky.social, @kiranmusunuru.bsky.social, ISCT President Miguel Forte & Chief Regulatory Officer Bambi Grilley to discuss #ethics #bioethics & technological hurdles of embryo editing www.isctglobal.org/telegrafthub...
Reposted by Bruce Levine, Ph.D. 🇺🇦
My CNBC.com segment on implications for pediatric vaccine schedule from recent politics. 2003 saw ~5,000 cases of pertusis, in 2024 there were over 35,000, and for 2025, some models show 70,000+
We risk a return of communicable diseases in children.
www.youtube.com/watch?v=00cI...
We risk a return of communicable diseases in children.
www.youtube.com/watch?v=00cI...
September 8, 2025 at 2:29 PM
My CNBC.com segment on implications for pediatric vaccine schedule from recent politics. 2003 saw ~5,000 cases of pertusis, in 2024 there were over 35,000, and for 2025, some models show 70,000+
We risk a return of communicable diseases in children.
www.youtube.com/watch?v=00cI...
We risk a return of communicable diseases in children.
www.youtube.com/watch?v=00cI...
Reposted by Bruce Levine, Ph.D. 🇺🇦
Reposted by Bruce Levine, Ph.D. 🇺🇦
How future cures begin as ideas in laboratories ft. Carl June, @bllphd.bsky.social (@pennpathlabmed.bsky.social), David Porter, Stephen Bagley, Jakub Svoboda (@penncancer.bsky.social) & Donald O'Rourke (@PennNSG) tinyurl.com/32hd7y2m
August 26, 2025 at 12:57 PM
How future cures begin as ideas in laboratories ft. Carl June, @bllphd.bsky.social (@pennpathlabmed.bsky.social), David Porter, Stephen Bagley, Jakub Svoboda (@penncancer.bsky.social) & Donald O'Rourke (@PennNSG) tinyurl.com/32hd7y2m
🚨Just published - Multiplex engineering using microRNA-mediated gene silencing in CAR T cells #celltherapy #genetherapy #immunotherapy www.frontiersin.org/journals/imm...
August 21, 2025 at 1:23 PM
🚨Just published - Multiplex engineering using microRNA-mediated gene silencing in CAR T cells #celltherapy #genetherapy #immunotherapy www.frontiersin.org/journals/imm...
Announcing the website for the song Ring That Bell 🔔 cowritten w @magsmccarthy.bsky.social an emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope. #cancer #cancerresearch #immunotherapy #hope ringthatbellsong.com
August 11, 2025 at 12:31 PM
Announcing the website for the song Ring That Bell 🔔 cowritten w @magsmccarthy.bsky.social an emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope. #cancer #cancerresearch #immunotherapy #hope ringthatbellsong.com
Reposted by Bruce Levine, Ph.D. 🇺🇦
Nearly two dozen people developed food poisoning in Florida after consuming tainted raw milk from the same farm, state health department says (from @reportergoodman.bsky.social) www.cnn.com/2025/08/05/h...
Nearly two dozen people in Florida are ill after drinking raw milk from the same farm | CNN
Nearly two dozen people have developed food poisoning in Florida after consuming tainted raw milk from the same farm, according to the state’s Department of Health.
www.cnn.com
August 8, 2025 at 12:20 PM
Nearly two dozen people developed food poisoning in Florida after consuming tainted raw milk from the same farm, state health department says (from @reportergoodman.bsky.social) www.cnn.com/2025/08/05/h...
🚨Coming soon! Multiplex engineering using microRNA-mediated gene silencing in CAR T cells. In a single lentiviral vector- multiplex silencing & expression of a CAR, better expansion & viability than gene editing by electroporation www.frontiersin.org/journals/imm...
Frontiers | Multiplex engineering using microRNA-mediated gene silencing in CAR T cells
Multiplex gene edited CAR T cell therapies face challenges, including potential oncogenic risks from double-strand breaks. Targeted microRNAs (miRNAs) may of...
www.frontiersin.org
August 5, 2025 at 1:05 PM
🚨Coming soon! Multiplex engineering using microRNA-mediated gene silencing in CAR T cells. In a single lentiviral vector- multiplex silencing & expression of a CAR, better expansion & viability than gene editing by electroporation www.frontiersin.org/journals/imm...
More disease coming, unfortunately in kids. Adults making the bad decisions for them.
Childhood Vaccination Rates Have Dropped Again, C.D.C. Data Shows www.nytimes.com/2025/07/31/h...
Childhood Vaccination Rates Have Dropped Again, C.D.C. Data Shows
www.nytimes.com
August 1, 2025 at 4:02 PM
More disease coming, unfortunately in kids. Adults making the bad decisions for them.
Reposted by Bruce Levine, Ph.D. 🇺🇦
My new 2-minute 5-point short on why one shouldn't go to stem cell clinics or at least seriously weigh risks + low chance of benefit. Good little video for scientists and physicians too looking for clear explanation when people ask #stemcells #stemcell www.youtube.com/shorts/EX9iU...
5 reasons not to go to a stem cell clinic
YouTube video by The Stem Cell Channel from The Niche
www.youtube.com
July 28, 2025 at 5:52 PM
My new 2-minute 5-point short on why one shouldn't go to stem cell clinics or at least seriously weigh risks + low chance of benefit. Good little video for scientists and physicians too looking for clear explanation when people ask #stemcells #stemcell www.youtube.com/shorts/EX9iU...
Cutting NIH to “save” money is fundamentally flawed
-Modest annual savings pale compared to multi‑trillion‑dollar health, innovation, and productivity losses www.statnews.com/2025/07/28/n...
-Modest annual savings pale compared to multi‑trillion‑dollar health, innovation, and productivity losses www.statnews.com/2025/07/28/n...
New analysis predicts sprawling effects of proposed NIH budget cuts
Initial analyses of the Trump administration’s proposed NIH cuts neglect key aspects of their long-term economic and health impact, study says.
www.statnews.com
July 28, 2025 at 11:47 AM
Cutting NIH to “save” money is fundamentally flawed
-Modest annual savings pale compared to multi‑trillion‑dollar health, innovation, and productivity losses www.statnews.com/2025/07/28/n...
-Modest annual savings pale compared to multi‑trillion‑dollar health, innovation, and productivity losses www.statnews.com/2025/07/28/n...
Reposted by Bruce Levine, Ph.D. 🇺🇦
From Pink Sheet on continued departures from FDA’s biologics division and challenges backfilling openings. FDA biologics center reported 106 departures from Jan. 1 to June 30. These numbers don’t include the 100-150 who were part of the reduction-in-force
insights.citeline.com/pink-sheet/a...
insights.citeline.com/pink-sheet/a...
US FDA’s Biologics Center Departures Grew Before More Than 100 RIFs Exited
The Center for Biologics Evaluation and Research saw departures far outnumber new hires in the second and third quarters of FY 2025, before more than 100 people left July 14 after the reduction-in-for...
insights.citeline.com
July 26, 2025 at 11:13 PM
From Pink Sheet on continued departures from FDA’s biologics division and challenges backfilling openings. FDA biologics center reported 106 departures from Jan. 1 to June 30. These numbers don’t include the 100-150 who were part of the reduction-in-force
insights.citeline.com/pink-sheet/a...
insights.citeline.com/pink-sheet/a...
Reposted by Bruce Levine, Ph.D. 🇺🇦
FDA’s cancer review team overseeing breast and gynecological products has lost about 1/3 of its medical review staff and the malignant heme group will lose about 2/3 of its medical review staff—all to voluntary resignations clustered among seasoned reviewers
insights.citeline.com/pink-sheet/a...
insights.citeline.com/pink-sheet/a...
July 26, 2025 at 1:57 PM
FDA’s cancer review team overseeing breast and gynecological products has lost about 1/3 of its medical review staff and the malignant heme group will lose about 2/3 of its medical review staff—all to voluntary resignations clustered among seasoned reviewers
insights.citeline.com/pink-sheet/a...
insights.citeline.com/pink-sheet/a...
There should be a cable channel fact checking all the cable news channels and their paid "pundits" in real time
CNN pundit Scott Jennings said almost 5 million nondisabled Medicaid recipients “simply choose not to work” and “spend six hours a day socializing and watching television.”
KFF Health News + @politifact.bsky.social rate this statement False. Read why. ⤵️ kffhealthnews.org/news/article...
KFF Health News + @politifact.bsky.social rate this statement False. Read why. ⤵️ kffhealthnews.org/news/article...
Are 5 Million Nondisabled Medicaid Recipients Watching TV All Day? That’s Unsupported - KFF Health News
CNN pundit Scott Jennings said almost 5 million nondisabled Medicaid recipients "simply choose not to work" and "spend six hours a day socializing and watching television." But a recent analysis found...
kffhealthnews.org
July 22, 2025 at 4:18 PM
There should be a cable channel fact checking all the cable news channels and their paid "pundits" in real time
If gifted narrative filmmaker Marwin Gansauge asks, "Can I make a movie about you?", what do you say? More than ever, science communication is desperately needed to convey the importance of research in developing new treatments for patients. Filmed in Vancouver & Dublin youtu.be/YrevpY-DNmw
July 21, 2025 at 11:51 AM
If gifted narrative filmmaker Marwin Gansauge asks, "Can I make a movie about you?", what do you say? More than ever, science communication is desperately needed to convey the importance of research in developing new treatments for patients. Filmed in Vancouver & Dublin youtu.be/YrevpY-DNmw
Reposted by Bruce Levine, Ph.D. 🇺🇦
Is Makary's FDA already heading toward a breaking point? ipscell.com/2025/07/is-m... #stemcells #stemcell #CRISPR what does it mean for the cell and gene therapy field?
Is Makary's FDA already heading toward a breaking point? - The Niche
Stem cell biologist writes about how Makary's FDA is already in serious trouble due to politics and a lack of experienced staff.
ipscell.com
July 16, 2025 at 7:21 PM
Is Makary's FDA already heading toward a breaking point? ipscell.com/2025/07/is-m... #stemcells #stemcell #CRISPR what does it mean for the cell and gene therapy field?
Reposted by Bruce Levine, Ph.D. 🇺🇦
How did the pandemic start?
I have avoided publicly commenting on this for 5 years. Here's my take as someone who has no stake at all in the game.
gidmk.substack.com/p/pandemic-r...
I have avoided publicly commenting on this for 5 years. Here's my take as someone who has no stake at all in the game.
gidmk.substack.com/p/pandemic-r...
Pandemic Revisionism, Part One: COVID-19 Origins
Because people keep getting this very wrong.
gidmk.substack.com
July 7, 2025 at 9:46 PM
How did the pandemic start?
I have avoided publicly commenting on this for 5 years. Here's my take as someone who has no stake at all in the game.
gidmk.substack.com/p/pandemic-r...
I have avoided publicly commenting on this for 5 years. Here's my take as someone who has no stake at all in the game.
gidmk.substack.com/p/pandemic-r...
If real facts matter to you
A new large study from Denmark finds no evidence that aluminum salts used in vaccines are tied to a higher risk of childhood diseases.
www.statnews.com/2025/07/14/a...
www.statnews.com/2025/07/14/a...
Study finds no evidence aluminum salts in vaccines are tied to higher risk of asthma, other childhood diseases
A new large study from Denmark finds no evidence that aluminum salts used in vaccines are tied to a higher risk of childhood diseases.
www.statnews.com
July 15, 2025 at 11:19 PM
If real facts matter to you
Reposted by Bruce Levine, Ph.D. 🇺🇦
Sign of the times.
July 15, 2025 at 8:49 PM
Sign of the times.
Reposted by Bruce Levine, Ph.D. 🇺🇦
A well-placed biotech investor says U.S. policies are straining life sciences startups — and more disruption is coming.
www.statnews.com/2025/07/15/b...
www.statnews.com/2025/07/15/b...
A well-placed biotech investor says U.S. policies are straining life sciences startups
A well-placed biotech investor says U.S. policies are straining life sciences startups — and more disruption is coming.
www.statnews.com
July 15, 2025 at 4:46 PM
A well-placed biotech investor says U.S. policies are straining life sciences startups — and more disruption is coming.
www.statnews.com/2025/07/15/b...
www.statnews.com/2025/07/15/b...
Taxing innovation
July 15, 2025 at 12:54 PM
Taxing innovation
TFW when UFC is valued > MIT is not AOK
July 11, 2025 at 11:26 AM
TFW when UFC is valued > MIT is not AOK
🧵1/3 How discoveries become cures, in a virtuous cycle
@pennmedicine.bsky.social
- Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures. #NIH pennmedicine.org/news/how-dis...
@pennmedicine.bsky.social
- Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures. #NIH pennmedicine.org/news/how-dis...
July 10, 2025 at 7:43 PM
🧵1/3 How discoveries become cures, in a virtuous cycle
@pennmedicine.bsky.social
- Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures. #NIH pennmedicine.org/news/how-dis...
@pennmedicine.bsky.social
- Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures. #NIH pennmedicine.org/news/how-dis...
🏋️Training Course! The Use of Cell Therapies for Autoimmune Diseases: CAR-T in #Paris Oct 16-17
#immunotherapy #autoimmune #Tcell #tcellrx @isctglobal.bsky.social
www.isctglobal.org/workforce-de...
#immunotherapy #autoimmune #Tcell #tcellrx @isctglobal.bsky.social
www.isctglobal.org/workforce-de...
July 9, 2025 at 7:17 PM
🏋️Training Course! The Use of Cell Therapies for Autoimmune Diseases: CAR-T in #Paris Oct 16-17
#immunotherapy #autoimmune #Tcell #tcellrx @isctglobal.bsky.social
www.isctglobal.org/workforce-de...
#immunotherapy #autoimmune #Tcell #tcellrx @isctglobal.bsky.social
www.isctglobal.org/workforce-de...