Bioinformatics Advances
bioinfoadv.bsky.social
Bioinformatics Advances
@bioinfoadv.bsky.social
A fully open access, peer-reviewed journal published jointly by Oxford University Press and the International Society for Computational Biology.
💻 BacExplorer is open source and freely available:
GitHub - knowmics-lab/BacExplorer
Contribute to knowmics-lab/BacExplorer development by creating an account on GitHub.
github.com
November 28, 2025 at 10:02 AM
It supports FASTA and FASTQ inputs, automates quality control, assembly, MLST typing, and AMR/virulence #gene detection across multiple databases, and generates comprehensive HTML and Excel reports for streamlined #microbiological analysis.
November 28, 2025 at 10:02 AM
BacExplorer is a cross-platform Snakemake-based tool with a user-friendly Electron interface for bacterial #genome annotation.
November 28, 2025 at 10:02 AM
Results show that even with large sample sizes, current methods fail to recover true metabolic interactions, though correlation-based approaches can still distinguish distinct metabolic states such as young versus aged networks in sarcopenia simulations.
November 27, 2025 at 10:01 AM
This study systematically benchmarks correlation-, regression-, and information theory-based network inference algorithms using a simulated arachidonic acid lipidomics model.
November 27, 2025 at 10:01 AM
It integrates over 306,000 representative genomes—more than doubling the number included in the GTDB—and provides standardized #taxonomy, functional annotations, and resources for #metagenomic profiling and #comparativegenomics.
November 26, 2025 at 10:01 AM
The GlobDB aggregates 14 independent #genomic catalogues to create a unified, species-dereplicated microbial genome database.
November 26, 2025 at 10:01 AM
💻 ntRoot is open source and available on GitHub:
GitHub - bcgsc/ntRoot: 🌳 Human ancestry inference from genomic data
🌳 Human ancestry inference from genomic data. Contribute to bcgsc/ntRoot development by creating an account on GitHub.
github.com
November 25, 2025 at 10:01 AM
Using Bloom filters and 1000 Genomes Project reference panels, ntRoot achieves 99–100% accuracy across 600+ samples while running up to 250x faster than ADMIXTURE, enabling efficient ancestry analysis at population scale.
November 25, 2025 at 10:01 AM
ntRoot is a lightweight, alignment-free method for inferring global and local #ancestry from #genome assemblies or sequencing data.
November 25, 2025 at 10:01 AM
🧬 BEREN is open source and freely available: https://gitlab.com/benminch1/BEREN  Associated data can be found at
Project - BEREN - Figshare
figshare.com
November 24, 2025 at 10:01 AM
Benchmarking on mock #metagenomes showed that BEREN recovered 77% of NCLDV contigs and 100% of Preplasmiviricota genomes, outperforming other virus recovery tools in accuracy and completeness.
November 24, 2025 at 10:01 AM
BEREN introduces a modular workflow for identifying, annotating, and analyzing members of the Bamfordvirae kingdom, including NCLDVs and Preplasmiviricota.
November 24, 2025 at 10:01 AM
Across #peptide classification and DNA barcoding datasets, the ensemble of #neuralnetworks outperformed traditional SVM and other baseline models.
November 21, 2025 at 10:01 AM
This study introduces a Wigner transform-based approach for converting one-dimensional biological feature vectors into two-dimensional matrices, enabling the use of CNNs and transformer networks pre-trained on image data.
November 21, 2025 at 10:01 AM