BaglaenkoLab
@baglaenkolab.bsky.social
The Baglaenko Lab of Immunogenetics in the Division of Human Genetics at Cincinnati Children's Hospital is focused on developing new experimental and computational approaches to answer the most difficult questions in inflammatory and infectious diseases.
Author here to answer any questions. The full protocol is online at protocols.io and all codebooks on github
Bring structure to your research - protocols.io
A secure platform for developing and sharing reproducible methods.
protocols.io
July 29, 2025 at 7:48 PM
Author here to answer any questions. The full protocol is online at protocols.io and all codebooks on github
Many many thanks to Soumya Raychaudhuri, Phoenix Mu, and every other co-author on this project. We are continuing to scale and implement these strategies in my lab, so reach out if that interests you.
July 23, 2025 at 3:22 PM
Many many thanks to Soumya Raychaudhuri, Phoenix Mu, and every other co-author on this project. We are continuing to scale and implement these strategies in my lab, so reach out if that interests you.
Happy to answer any and all questions about this work. We'd love to see more people try it.
Full protocol: www.protocols.io/view/craftse...
Full analysis: github.com/immunogenomi...
Full protocol: www.protocols.io/view/craftse...
Full analysis: github.com/immunogenomi...
CRAFTseq
Genetic studies have identified thousands of individual disease-associated non-coding alleles, but identification of the causal alleles and their functions remain critical bottl...
www.protocols.io
July 23, 2025 at 3:22 PM
Happy to answer any and all questions about this work. We'd love to see more people try it.
Full protocol: www.protocols.io/view/craftse...
Full analysis: github.com/immunogenomi...
Full protocol: www.protocols.io/view/craftse...
Full analysis: github.com/immunogenomi...
This plate based approach is highly adaptable and easy (enough) to implement without specialized equipment. We show that this is a robust and reliable way to functionally validate causal genetic variants directly in CRISPR editing cells.
July 23, 2025 at 3:22 PM
This plate based approach is highly adaptable and easy (enough) to implement without specialized equipment. We show that this is a robust and reliable way to functionally validate causal genetic variants directly in CRISPR editing cells.