Ennio
@amicoennio.bsky.social
A biochemist. Molecular motors, especially dynein
Reposted by Ennio
Excited to share our new paper! 🎉
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
www.science.org/doi/10.1126/...
Very thankful to @andrea-musacchio.bsky.social for his mentorship and support over the years.
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
www.science.org/doi/10.1126/...
Very thankful to @andrea-musacchio.bsky.social for his mentorship and support over the years.
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
The kinetochore fibrous corona docks on CENP-E and a second elusive receptor identified as the checkpoint protein BUB1.
www.science.org
September 15, 2025 at 8:26 PM
Excited to share our new paper! 🎉
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
www.science.org/doi/10.1126/...
Very thankful to @andrea-musacchio.bsky.social for his mentorship and support over the years.
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
www.science.org/doi/10.1126/...
Very thankful to @andrea-musacchio.bsky.social for his mentorship and support over the years.
Reposted by Ennio
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/...
Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle
Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
The kinetochore fibrous corona docks on CENP-E and a second elusive receptor identified as the checkpoint protein BUB1.
www.science.org
September 15, 2025 at 4:50 AM
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/...
Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle
Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle
The power of collaboration (and of in vitro reconstitution)!
Schweighofer, Mulay, @andrea-musacchio.bsky.social et al. reconstitute direct interactions between FAcilitates Chromatin Transcription and the 16-subunit constitutive centromere–associated network core of the chromatin-proximal #kinetochore rupress.org/jcb/article/...
#mitosis
#mitosis
March 17, 2025 at 8:02 PM
The power of collaboration (and of in vitro reconstitution)!
Reposted by Ennio
New: Colombo et al. @surreylab.bsky.social show that NuMA is a mitotic dynein adaptor that binds and caps microtubule minus ends, explaining how dynein, NuMA, dynactin, and Lis1 focus microtubule minus ends at mitotic spindle poles https://buff.ly/41aj9F9
February 11, 2025 at 6:21 PM
New: Colombo et al. @surreylab.bsky.social show that NuMA is a mitotic dynein adaptor that binds and caps microtubule minus ends, explaining how dynein, NuMA, dynactin, and Lis1 focus microtubule minus ends at mitotic spindle poles https://buff.ly/41aj9F9
Excited to share the first published paper of my postdoc - a collaboration with Yildiz and Dumont groups led by Merve Aslan, on the fascinating dynein adaptor NuMA. Lots of super cool insights on how NuMA can activate dynein during mitosis. Thanks to @carter-lab.bsky.social for the support!
www.biorxiv.org
December 8, 2024 at 6:09 PM
Excited to share the first published paper of my postdoc - a collaboration with Yildiz and Dumont groups led by Merve Aslan, on the fascinating dynein adaptor NuMA. Lots of super cool insights on how NuMA can activate dynein during mitosis. Thanks to @carter-lab.bsky.social for the support!
Reposted by Ennio
Our #CryoET paper on ciliary rootlet ultrastructure from mouse retina is now out in @elife.bsky.social! Have a peek with this video or dive deeper at bit.ly/3ZJzhgc. Big thanks to @carter-lab.bsky.social and #teamtomo.
#CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science
#CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science
December 8, 2024 at 2:38 PM
Our #CryoET paper on ciliary rootlet ultrastructure from mouse retina is now out in @elife.bsky.social! Have a peek with this video or dive deeper at bit.ly/3ZJzhgc. Big thanks to @carter-lab.bsky.social and #teamtomo.
#CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science
#CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science
Brilliant and supportive mentor, great location, exciting project - what's not to love? Plus a unique opportunity to really learn from the best at figuremaking!
If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪
November 27, 2024 at 3:30 PM
Brilliant and supportive mentor, great location, exciting project - what's not to love? Plus a unique opportunity to really learn from the best at figuremaking!
First #JournalClub on the blue side: an exciting story about dynein at the kinetochore and its role in biorientation!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore - Nature Communications
Mitotic chromosomes recruit multiple microtubule-directed activities to ensure their faithful segregation. Using an approach where only one major activity is present, the authors reveal sufficiency of...
www.nature.com
November 15, 2024 at 11:30 AM
First #JournalClub on the blue side: an exciting story about dynein at the kinetochore and its role in biorientation!
www.nature.com/articles/s41...
www.nature.com/articles/s41...