Ainsley Beaton
@ainsley-beaton.bsky.social
PDRA at the University of Glasgow 🧫🧬
Also interested in rugby, books and cycling
Also interested in rugby, books and cycling
Reposted by Ainsley Beaton
The 2026 Barkley Marathons began with one of the strongest fields ever. The starting field came from 15 Counties as well as 15 States, and included ten women. The course seemed not to care. Over 70% of the field is done. #BM100
February 15, 2026 at 12:34 AM
The 2026 Barkley Marathons began with one of the strongest fields ever. The starting field came from 15 Counties as well as 15 States, and included ten women. The course seemed not to care. Over 70% of the field is done. #BM100
Reposted by Ainsley Beaton
A microscope that cost less than £50 and took under 3 hours to build using a common 3D printer could be transformative for students and researchers with limited funding
The world’s first fully 3D-printed microscope blew up in 2025
A microscope that cost less than £50 and took under 3 hours to build using a common 3D printer could be transformative for students and researchers with limited funding
www.newscientist.com
December 25, 2025 at 3:01 PM
A microscope that cost less than £50 and took under 3 hours to build using a common 3D printer could be transformative for students and researchers with limited funding
Reposted by Ainsley Beaton
Exceptional young performers reached their peak quickly but narrowly mastered only one interest.
By contrast, exceptional adults reached peak performance gradually with broader, multidisciplinary practice.
However, elite programs are designed to nurture younger talent.
By contrast, exceptional adults reached peak performance gradually with broader, multidisciplinary practice.
However, elite programs are designed to nurture younger talent.
December 21, 2025 at 4:16 PM
Exceptional young performers reached their peak quickly but narrowly mastered only one interest.
By contrast, exceptional adults reached peak performance gradually with broader, multidisciplinary practice.
However, elite programs are designed to nurture younger talent.
By contrast, exceptional adults reached peak performance gradually with broader, multidisciplinary practice.
However, elite programs are designed to nurture younger talent.
Reposted by Ainsley Beaton
New preprint. Work led by @ainsley-beaton.bsky.social & Rebecca Devine.
They show the highly conserved Streptomyces MtrAB two component system activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae
www.biorxiv.org/content/10.6...
They show the highly conserved Streptomyces MtrAB two component system activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae
www.biorxiv.org/content/10.6...
MtrAB activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae
The MtrAB two-component system is a master regulator of antibiotic biosynthesis in Streptomyces species. MtrA is also required for sporulation under certain growth conditions, which means that on some...
www.biorxiv.org
December 22, 2025 at 7:19 AM
New preprint. Work led by @ainsley-beaton.bsky.social & Rebecca Devine.
They show the highly conserved Streptomyces MtrAB two component system activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae
www.biorxiv.org/content/10.6...
They show the highly conserved Streptomyces MtrAB two component system activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae
www.biorxiv.org/content/10.6...
Reposted by Ainsley Beaton
bioRxiv by @ainsley-beaton.bsky.social from @matthutchings.bsky.social on the role of MtrAB in Streptomyces venezuelae
MtrAB activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae https://www.biorxiv.org/content/10.64898/2025.12.19.695424v1
December 22, 2025 at 6:45 AM
bioRxiv by @ainsley-beaton.bsky.social from @matthutchings.bsky.social on the role of MtrAB in Streptomyces venezuelae
Reposted by Ainsley Beaton
Delighted to see the main work from my PhD finally published in @mbio.bsky.social! It all started with the observation that deleting the cutRS two-component system in S. venezuelae caused this amazing explorer phenotype in the presence of glucose. But what was going on?! (1/n)
December 16, 2025 at 2:40 AM
Delighted to see the main work from my PhD finally published in @mbio.bsky.social! It all started with the observation that deleting the cutRS two-component system in S. venezuelae caused this amazing explorer phenotype in the presence of glucose. But what was going on?! (1/n)
Reposted by Ainsley Beaton
Very happy to see this remarkable work published. Led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. We show how Streptomyces bacteria sense & respond to misfolded secreted proteins. A great collaboration with @barriewilks.bsky.social
#microsky
1/2
journals.asm.org/doi/epub/10....
#microsky
1/2
journals.asm.org/doi/epub/10....
The conserved two-component systems CutRS and CssRS control the protein secretion stress response in Streptomyces
journals.asm.org
December 15, 2025 at 2:39 PM
Very happy to see this remarkable work published. Led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. We show how Streptomyces bacteria sense & respond to misfolded secreted proteins. A great collaboration with @barriewilks.bsky.social
#microsky
1/2
journals.asm.org/doi/epub/10....
#microsky
1/2
journals.asm.org/doi/epub/10....
Reposted by Ainsley Beaton
PhD opportunity to come and work in Glasgow, developing advanced tissue culture models to study Staphylococcus aureus colonisation and infection #microsky #PhD #DTPprogram
Enquiries from potential applicants are welcome.
www.gla.ac.uk/postgraduate...
www.findaphd.com/phds/program...
Enquiries from potential applicants are welcome.
www.gla.ac.uk/postgraduate...
www.findaphd.com/phds/program...
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Understanding Pathogens, from Molecules to Phenotypes - Justine Rudkin
www.gla.ac.uk
September 30, 2025 at 12:52 PM
PhD opportunity to come and work in Glasgow, developing advanced tissue culture models to study Staphylococcus aureus colonisation and infection #microsky #PhD #DTPprogram
Enquiries from potential applicants are welcome.
www.gla.ac.uk/postgraduate...
www.findaphd.com/phds/program...
Enquiries from potential applicants are welcome.
www.gla.ac.uk/postgraduate...
www.findaphd.com/phds/program...
It can only be a last day when there are this number of primers in the bin
June 27, 2025 at 11:13 AM
It can only be a last day when there are this number of primers in the bin
Don’t know why I’d never thought of a commute coffee before now
June 17, 2025 at 7:39 AM
Don’t know why I’d never thought of a commute coffee before now
8 am on a Monday. Do I just go home?
April 7, 2025 at 7:30 AM
8 am on a Monday. Do I just go home?
After a great week at #microbio25 I’m set up on the train with a good book and a coffee which is the perfect way to travel 📚. That’s if the last few nights of missing my 9pm bed time in favour of the pub don’t mean that I immediately fall asleep 🤣
April 3, 2025 at 1:01 PM
After a great week at #microbio25 I’m set up on the train with a good book and a coffee which is the perfect way to travel 📚. That’s if the last few nights of missing my 9pm bed time in favour of the pub don’t mean that I immediately fall asleep 🤣
@liam-rooney.bsky.social gave an incredibly interesting talk about novel imaging techniques for infection biology and that’s great BUT look at the tiny wee sad face inside this digitally cross sectioned and optically clear galleria is! It looks like how I feel in the mornings
April 2, 2025 at 2:29 PM
@liam-rooney.bsky.social gave an incredibly interesting talk about novel imaging techniques for infection biology and that’s great BUT look at the tiny wee sad face inside this digitally cross sectioned and optically clear galleria is! It looks like how I feel in the mornings
And so begins a very long train journey from Norwich to Liverpool via every stop in between for Microsoc 2025
March 31, 2025 at 5:59 AM
And so begins a very long train journey from Norwich to Liverpool via every stop in between for Microsoc 2025
Reposted by Ainsley Beaton
dussl's making headlines! 🌞
Why one Glaswegian is marketing SPF to Scotland's wettest city.
heraldscotland.com/news/25028013.one-glaswegian-marketing-spf-scotlands-wettest-city/?ref=li
Why one Glaswegian is marketing SPF to Scotland's wettest city.
heraldscotland.com/news/25028013.one-glaswegian-marketing-spf-scotlands-wettest-city/?ref=li
Why one Glaswegian is marketing SPF to Scotland's wettest city
Meet the 30-year-old entrepreneur behind dussl, the Glasgow skincare brand selling sunscreen to the UK city where it rains nearly 200 days a year.
www.heraldscotland.com
March 24, 2025 at 11:20 AM
dussl's making headlines! 🌞
Why one Glaswegian is marketing SPF to Scotland's wettest city.
heraldscotland.com/news/25028013.one-glaswegian-marketing-spf-scotlands-wettest-city/?ref=li
Why one Glaswegian is marketing SPF to Scotland's wettest city.
heraldscotland.com/news/25028013.one-glaswegian-marketing-spf-scotlands-wettest-city/?ref=li
Reposted by Ainsley Beaton
Very happy to share this work led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. The conserved Streptomyces sensor kinase CutS senses disulphide bond formation outside the cell. If it fails CutS activates CutR which switches on production of foldase HtrA3
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Extracellular redox sensors control the protein secretion stress response in Streptomyces
Translocating unfolded polypeptides across membranes is essential in all domains of life and in bacteria requires the conserved Sec machinery and ATP. Bacterial Sec substrates fold outside the cell an...
www.biorxiv.org
March 21, 2025 at 8:19 AM
Very happy to share this work led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. The conserved Streptomyces sensor kinase CutS senses disulphide bond formation outside the cell. If it fails CutS activates CutR which switches on production of foldase HtrA3
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Further insight into how CutRS functions in Streptomyces and some thoughts on how its redox state detection via conserved dual cysteine residues in the extra cellular domain of a sensor kinase may be present in almost all bacteria
@tommclean.bsky.social
@matthutchings.bsky.social
@tommclean.bsky.social
@matthutchings.bsky.social
Extracellular redox sensors control the protein secretion stress response in Streptomyces https://www.biorxiv.org/content/10.1101/2025.03.20.644377v1
March 21, 2025 at 7:22 AM
Further insight into how CutRS functions in Streptomyces and some thoughts on how its redox state detection via conserved dual cysteine residues in the extra cellular domain of a sensor kinase may be present in almost all bacteria
@tommclean.bsky.social
@matthutchings.bsky.social
@tommclean.bsky.social
@matthutchings.bsky.social
Reposted by Ainsley Beaton
Redox control of antibiotic biosynthesis in Streptomyces.
Remarkable work led by @katienoble241.bsky.social and Rebecca Devine demonstrates why antibiotic biosynthesis is often switched on in solid cultures and off in liquid.
www.biorxiv.org/content/10.1...
Remarkable work led by @katienoble241.bsky.social and Rebecca Devine demonstrates why antibiotic biosynthesis is often switched on in solid cultures and off in liquid.
www.biorxiv.org/content/10.1...
Redox control of antibiotic biosynthesis
Streptomyces bacteria make diverse specialised metabolites that form the basis of ~55% of clinically used antibiotics. Despite this, only 3% of their encoded specialised metabolites have been matched ...
www.biorxiv.org
March 10, 2025 at 8:39 PM
Redox control of antibiotic biosynthesis in Streptomyces.
Remarkable work led by @katienoble241.bsky.social and Rebecca Devine demonstrates why antibiotic biosynthesis is often switched on in solid cultures and off in liquid.
www.biorxiv.org/content/10.1...
Remarkable work led by @katienoble241.bsky.social and Rebecca Devine demonstrates why antibiotic biosynthesis is often switched on in solid cultures and off in liquid.
www.biorxiv.org/content/10.1...
First #toadwatch of the season and it was busy! 28 toads and 8 frogs were given a lift to the pond 🐸
Toads return to the pond they spawned in each year to breed, often covering great distances to do so. Due to habitat fragmentation they are increasingly killed by cars whilst on their journey
Toads return to the pond they spawned in each year to breed, often covering great distances to do so. Due to habitat fragmentation they are increasingly killed by cars whilst on their journey
March 7, 2025 at 8:37 PM
First #toadwatch of the season and it was busy! 28 toads and 8 frogs were given a lift to the pond 🐸
Toads return to the pond they spawned in each year to breed, often covering great distances to do so. Due to habitat fragmentation they are increasingly killed by cars whilst on their journey
Toads return to the pond they spawned in each year to breed, often covering great distances to do so. Due to habitat fragmentation they are increasingly killed by cars whilst on their journey
It’s official @tommclean.bsky.social and I have peaked in terms of our scientific writing 📄
March 3, 2025 at 10:48 AM
It’s official @tommclean.bsky.social and I have peaked in terms of our scientific writing 📄
Wonderfully artistic advertising from @microbesng.bsky.social. They are already my favourite sticker maker and now we may need to add posters and plasmid sequencing to that
February 27, 2025 at 9:08 AM
Wonderfully artistic advertising from @microbesng.bsky.social. They are already my favourite sticker maker and now we may need to add posters and plasmid sequencing to that
Reposted by Ainsley Beaton
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
February 21, 2025 at 8:42 PM
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
Reposted by Ainsley Beaton
VACANCY - We’re seeking a Proteomics Scientist to work alongside our experienced platform manager to help serve the growing needs of proteomics-based technology at the John Innes Centre (JIC).
www.jic.ac.uk/vacancies/pr...
Closing date - 2 March 2025
Contract - Full-time, indefinite
www.jic.ac.uk/vacancies/pr...
Closing date - 2 March 2025
Contract - Full-time, indefinite
Proteomics Scientist | John Innes Centre
The John Innes Centre (JIC) seeks a talented, motivated individual as a proteomics specialist to serve the growing needs of proteomics-based technology at JIC, which is a globally recognized…
www.jic.ac.uk
February 12, 2025 at 8:41 AM
VACANCY - We’re seeking a Proteomics Scientist to work alongside our experienced platform manager to help serve the growing needs of proteomics-based technology at the John Innes Centre (JIC).
www.jic.ac.uk/vacancies/pr...
Closing date - 2 March 2025
Contract - Full-time, indefinite
www.jic.ac.uk/vacancies/pr...
Closing date - 2 March 2025
Contract - Full-time, indefinite