Afroze Chimthanawala
@afrozec.bsky.social
Postdoctoral researcher at Kapanidis Lab, Kavli Institute for Nanoscience Discovery | Former Postdoctoral researcher at Saurabh Lab, NYU | PhD at Badrinarayanan Lab, NCBS (TIFR)
Reposted by Afroze Chimthanawala
1/ With @maxencevincent.bsky.social, we ask: when single bacterial cells behave differently under stress, is it really just “noise”?
Read more @cp-cellreports.bsky.social :
Unveiling hidden variables in stressed bacteria (doi.org/10.1016/j.ce...)
Read more @cp-cellreports.bsky.social :
Unveiling hidden variables in stressed bacteria (doi.org/10.1016/j.ce...)
Redirecting
doi.org
February 11, 2026 at 5:30 AM
1/ With @maxencevincent.bsky.social, we ask: when single bacterial cells behave differently under stress, is it really just “noise”?
Read more @cp-cellreports.bsky.social :
Unveiling hidden variables in stressed bacteria (doi.org/10.1016/j.ce...)
Read more @cp-cellreports.bsky.social :
Unveiling hidden variables in stressed bacteria (doi.org/10.1016/j.ce...)
Reposted by Afroze Chimthanawala
Review @cp-cellreports.bsky.social @harvard.edu
Unveiling hidden variables in stressed bacteria
www.cell.com/cell-reports...
Unveiling hidden variables in stressed bacteria
www.cell.com/cell-reports...
February 11, 2026 at 9:52 PM
Review @cp-cellreports.bsky.social @harvard.edu
Unveiling hidden variables in stressed bacteria
www.cell.com/cell-reports...
Unveiling hidden variables in stressed bacteria
www.cell.com/cell-reports...
Reposted by Afroze Chimthanawala
🦠💫 RNA modifications and stress
Epitranscriptomic control of stress adaptations in Escherichia coli
Abstract. The impacts of various stressors on bacterial systems have been studied at the phenotypic, transcriptional, and translational levels during the e
academic.oup.com
February 4, 2026 at 9:27 AM
🦠💫 RNA modifications and stress
Reposted by Afroze Chimthanawala
To accommodate for extra spots made available, we're reopening the abstract deadline for the SMBio26 organized together with the University of Sheffield!
Organized with the @sheffielduni.bsky.social team: Matt Newton, @alicepyne.bsky.social & Ruby Peters.
Program & registration 👉 bit.ly/3NtxZlM
Organized with the @sheffielduni.bsky.social team: Matt Newton, @alicepyne.bsky.social & Ruby Peters.
Program & registration 👉 bit.ly/3NtxZlM
February 4, 2026 at 3:56 PM
To accommodate for extra spots made available, we're reopening the abstract deadline for the SMBio26 organized together with the University of Sheffield!
Organized with the @sheffielduni.bsky.social team: Matt Newton, @alicepyne.bsky.social & Ruby Peters.
Program & registration 👉 bit.ly/3NtxZlM
Organized with the @sheffielduni.bsky.social team: Matt Newton, @alicepyne.bsky.social & Ruby Peters.
Program & registration 👉 bit.ly/3NtxZlM
Reposted by Afroze Chimthanawala
Dynamic RNA Polymerase compartments organize the transcription of gene clusters https://www.biorxiv.org/content/10.64898/2026.01.07.698080v1
January 8, 2026 at 2:32 PM
Dynamic RNA Polymerase compartments organize the transcription of gene clusters https://www.biorxiv.org/content/10.64898/2026.01.07.698080v1
Reposted by Afroze Chimthanawala
Hey alpha aficionados - it's almost time for CauloCon 2026! This free, virtual meeting will feature talks from @brunlabcaulo.bsky.social @thanbichlerlab.bsky.social and @lamasonlab.bsky.social with opps for trainee talks. Register using the link below. 👇
CauloCon 2026 is coming! 🔬✨ March 3–5 (fully virtual + free). Keynotes by Yves Brun, Becky Lamason & Martin Thanbichler. Great chance for grad students & postdocs to present their work (work-in-progress welcome!). Submit an abstract by Sun Feb 8. Register + submit: www.caulocon.com
CauloCon 2026
A free, 3-day virtual meeting on all things Caulobacter and Alphaproteobacteria
www.caulocon.com
February 2, 2026 at 6:58 PM
Hey alpha aficionados - it's almost time for CauloCon 2026! This free, virtual meeting will feature talks from @brunlabcaulo.bsky.social @thanbichlerlab.bsky.social and @lamasonlab.bsky.social with opps for trainee talks. Register using the link below. 👇
Reposted by Afroze Chimthanawala
Great to see our Science Review on emerging multiplexed single-molecule methods that use libraries to link sequence to dynamics. A fun collaborative writing project! From sequence to function: Bridging single-molecule kinetics and molecular diversity | Science www.science.org/doi/10.1126/...
From sequence to function: Bridging single-molecule kinetics and molecular diversity
Biological function is fundamentally determined by nucleic acid and protein sequence. Beyond encoding genetic information, nucleic acids also display complex physicochemical parameters that shape stru...
www.science.org
January 30, 2026 at 6:59 PM
Great to see our Science Review on emerging multiplexed single-molecule methods that use libraries to link sequence to dynamics. A fun collaborative writing project! From sequence to function: Bridging single-molecule kinetics and molecular diversity | Science www.science.org/doi/10.1126/...
Reposted by Afroze Chimthanawala
New preprint! We share a new *DNA-only* method for single-molecule DNA sequencing, and use this cool tool to link single-molecule reactions/interactions to sequence. Big thanks🙏 to Jagadish Hazra @becs-andrews.bsky.social and all contributors since our 2016 start!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing
DNA sequence regulates complex reactions and protein-DNA interactions, yet sequence effects remain poorly understood due to the lack of direct, high-throughput approaches to study sequence-dependence ...
www.biorxiv.org
December 5, 2025 at 12:04 PM
New preprint! We share a new *DNA-only* method for single-molecule DNA sequencing, and use this cool tool to link single-molecule reactions/interactions to sequence. Big thanks🙏 to Jagadish Hazra @becs-andrews.bsky.social and all contributors since our 2016 start!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Afroze Chimthanawala
1/Now published! We identify a novel regulatory layer underlying SOS response dynamic. Find a short summary about our findings below.
journals.plos.org/plosbiology/...
#MicroSky
journals.plos.org/plosbiology/...
#MicroSky
Variability in intrinsic promoter strength underlies the temporal hierarchy of the Caulobacter SOS response induction
The bacterial SOS response unfolds in a defined temporal order, but the determinants of this hierarchy are unclear. This study shows that intrinsic promoter strength, modulated in part by sigma factor...
journals.plos.org
December 10, 2025 at 1:46 PM
1/Now published! We identify a novel regulatory layer underlying SOS response dynamic. Find a short summary about our findings below.
journals.plos.org/plosbiology/...
#MicroSky
journals.plos.org/plosbiology/...
#MicroSky
Reposted by Afroze Chimthanawala
Apply now to attend the next EMBO Bacterial Networks meeting #EMBOBacNet
🗓️13-18 September 2026
📍Sant Feliu de Guixols, Spain
📝Program and registration info: meetings.embo.org/event/26-bac...
👩🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social
#MicroSky
🗓️13-18 September 2026
📍Sant Feliu de Guixols, Spain
📝Program and registration info: meetings.embo.org/event/26-bac...
👩🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social
#MicroSky
November 20, 2025 at 10:16 AM
Apply now to attend the next EMBO Bacterial Networks meeting #EMBOBacNet
🗓️13-18 September 2026
📍Sant Feliu de Guixols, Spain
📝Program and registration info: meetings.embo.org/event/26-bac...
👩🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social
#MicroSky
🗓️13-18 September 2026
📍Sant Feliu de Guixols, Spain
📝Program and registration info: meetings.embo.org/event/26-bac...
👩🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social
#MicroSky
Reposted by Afroze Chimthanawala
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Genome integrity relies on rapid recycling of DNA Pol III in bacteria | PNAS
DNA replication requires precise coordination between DNA unwinding and DNA synthesis.
In all domains of life, protein–protein interactions at the ...
www.pnas.org
November 20, 2025 at 4:54 PM
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!