@adamgrippin.bsky.social
PGY5 RadOnc resident at @MDAndersonNews 🩺 | @UFMDPhD '21 | Translational research | Cancer Immunotherapy | RNA vaccines | views are my own
Reposted
We are excited to share the Venkatesh Lab’s first publication in collaboration with @michellemonje.bsky.social team uncovering how neuronal activity influences the progression of small cell lung cancer #SCLC in the lung and brain. www.nature.com/articles/s41...
Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis - Nature
Glutamatergic and GABAergic (γ-aminobutyric acid-producing) cortical neuronal activity drives proliferation of small lung cell cancer via paracrine interactions and through synapses formed with tumour...
www.nature.com
September 16, 2025 at 1:33 PM
We are excited to share the Venkatesh Lab’s first publication in collaboration with @michellemonje.bsky.social team uncovering how neuronal activity influences the progression of small cell lung cancer #SCLC in the lung and brain. www.nature.com/articles/s41...
Reposted
Plasmacytoid dendritic cells can transition to become cDC2s under to influence of TNF, while type-I interferon reduces TNFR expression and thereby inhibits transition. These transitioned cDC2 seem fully functional. 🧪 ⑂
Hornero et al 2025 in Nat Immunol
www.nature.com/articles/s41...
Hornero et al 2025 in Nat Immunol
www.nature.com/articles/s41...
September 11, 2025 at 2:51 AM
Plasmacytoid dendritic cells can transition to become cDC2s under to influence of TNF, while type-I interferon reduces TNFR expression and thereby inhibits transition. These transitioned cDC2 seem fully functional. 🧪 ⑂
Hornero et al 2025 in Nat Immunol
www.nature.com/articles/s41...
Hornero et al 2025 in Nat Immunol
www.nature.com/articles/s41...
Reposted
"In vivo CAR T cell generation to treat cancer and
autoimmune disease"
...as if millions of cell therapy CDMOs suddenly cried out in terror and were suddenly silenced...
www.science.org/doi/10.1126/...
autoimmune disease"
...as if millions of cell therapy CDMOs suddenly cried out in terror and were suddenly silenced...
www.science.org/doi/10.1126/...
In vivo CAR T cell generation to treat cancer and autoimmune disease
Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...
www.science.org
August 20, 2025 at 6:24 PM
"In vivo CAR T cell generation to treat cancer and
autoimmune disease"
...as if millions of cell therapy CDMOs suddenly cried out in terror and were suddenly silenced...
www.science.org/doi/10.1126/...
autoimmune disease"
...as if millions of cell therapy CDMOs suddenly cried out in terror and were suddenly silenced...
www.science.org/doi/10.1126/...
Reposted
Congratulations @doudna-lab.bsky.social !! History will position her name alongside the likes of Darwin, Einstein, and Hodgkin.
Jennifer A. Doudna will receive the 2026 Priestley Medal, the highest honor given out by the American Chemical Society. She helped discover the gene editing technology CRISPR and has made many contributions to our knowledge of RNA chemistry. cen.acs.org/people/award...
Jennifer Doudna is named 2026 Priestley Medalist
The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership
cen.acs.org
August 9, 2025 at 5:21 PM
Congratulations @doudna-lab.bsky.social !! History will position her name alongside the likes of Darwin, Einstein, and Hodgkin.
Reposted
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/45uez6N
go.nature.com/45uez6N
‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Nature - Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
go.nature.com
August 2, 2025 at 4:32 PM
Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse
go.nature.com/45uez6N
go.nature.com/45uez6N
Reposted
Our latest paper in collaboration with @jacques-lux.bsky.social describing using #US to activate #sting for #cancerimmunotherapy is now online in AdvScience. @mdanderson.bsky.social @utswtxid.bsky.social
Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microb...
advanced.onlinelibrary.wiley.com
March 26, 2025 at 1:43 PM
Our latest paper in collaboration with @jacques-lux.bsky.social describing using #US to activate #sting for #cancerimmunotherapy is now online in AdvScience. @mdanderson.bsky.social @utswtxid.bsky.social
Reposted
Betty Kim & Wen Jiang and colleagues report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
@bettykimmdphd.bsky.social @wenjiang-nano.bsky.social @mdanderson.bsky.social
⬇️
www.nature.com/articles/s43...
@bettykimmdphd.bsky.social @wenjiang-nano.bsky.social @mdanderson.bsky.social
⬇️
www.nature.com/articles/s43...
An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy - Nature Cancer
Schrank et al. report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
www.nature.com
March 22, 2025 at 10:07 AM
Betty Kim & Wen Jiang and colleagues report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
@bettykimmdphd.bsky.social @wenjiang-nano.bsky.social @mdanderson.bsky.social
⬇️
www.nature.com/articles/s43...
@bettykimmdphd.bsky.social @wenjiang-nano.bsky.social @mdanderson.bsky.social
⬇️
www.nature.com/articles/s43...