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a-wayne-orr.bsky.social
Wayne Orr
@a-wayne-orr.bsky.social
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Reposted by Wayne Orr
blacoste.bsky.social
Fantastic new work led by @milenevandal.bsky.social showing that loss of brain endothelial CD2AP in mice alters memory and cerebrovascular function. Interestingly, mutations in CD2AP are known to predispose to Alzheimer’s disease! #cerebrovascular
Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction
Vandal et al. performed a biological sex-based study on the role of the Alzheimer’s disease (AD) genetic factor CD2AP in brain blood vessels. Using mouse models and human AD samples, they identified a...
www.cell.com
February 1, 2025 at 3:43 PM
Reposted by Wayne Orr
blekhman.bsky.social
Submitting an NIH grant right now
January 28, 2025 at 9:11 PM
Reposted by Wayne Orr
science.org
"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors."

One mentor isn’t enough, wrote Erika Moore in this 2021 #ScienceWorkingLife essay. https://scim.ag/3DWR4YV #NationalMentoringMonth
Illustration showing a diverse group of four people standing in a line, with a person at the right looking back at them with an arm extended. The image features a caption that reads, "WORKING LIFE — One mentor isn’t enough. Here's how I build a network of mentors."
January 19, 2025 at 3:07 PM
Reposted by Wayne Orr
biorxiv-cellbio.bsky.social
VE-cadherin RGD motifs are dispensable for cell-cell junctions, endothelial barrier function and leukocyte extravasation https://www.biorxiv.org/content/10.1101/2025.01.08.631898v1
January 11, 2025 at 5:30 AM