Will Branchett
@wjbranchett.bsky.social
52 followers 80 following 3 posts
Mucosal immunologist at the Francis Crick Institute, London
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Reposted by Will Branchett
jem.org
Stetsenko et al. show that TCR clonotypes from individuals latently infected w/ M. #tuberculosis demonstrate dominant but not exclusive recognition of infected #macrophages, specificity for type VII secretion system substrates, & expression of canonical effector programs rupress.org/jem/article/...
wjbranchett.bsky.social
Pleased to see this out now in @jem.org 🔬

We characterise the early immune response during M. tuberculosis infection in mouse models and demonstrate a detrimental role for type I interferon activated neutrophils in TB lesions. Thanks to all involved @crick.ac.uk and i3S, Porto.
jem.org
William J. Branchett, Anne O’Garra @crick.ac.uk et al. reveal that type I signaling early during M. #tuberculosis infection favors #neutrophil swarming and limits CD4+ T cell–#macrophage interactions in #TB lesions, impeding TB disease control. rupress.org/jem/article/...
wjbranchett.bsky.social
Great day out talking all things infection at #LINEsymposium2025 today. Thanks for having me!
londoninfectionecr.bsky.social
We are heading straight into session 3 of our selected talks. @wjbranchett.bsky.social @crick.ac.uk is up first, focussing on M. tuberculosis infection. #LINEsymposium2025
wjbranchett.bsky.social
Looking forward to presenting our work on early mechanisms of TB susceptibility at the @londoninfectionecr.bsky.social Symposium in June 🦠🔬
londoninfectionecr.bsky.social
We can see our ECR-focused LINE symposium already on the horizon (9th of June) @crick.ac.uk. shorturl.at/MyWNl 🥳
You can submit your abstracts (talk or poster) until the EXTENDED DEADLINE on the 12th of May here: shorturl.at/7KuXL
Free registration shorturl.at/wLyWY
We're excited to see you there!
This is  a poster advertising the LINE scientific symposium aimed at early career researchers working in infection. Displayed is an electron microscope image showing two salmonella bacteria attached to a cells causing the cell membrane to ripple. Below the image, the organisational details about the symposium are shown.