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Spang Lab

@spanglab.bsky.social

410 followers 100 following 9 posts

We are scientists interested in understanding the basics of how a cell, the building block of our body, works. @biozentrum @UniBasel_en #cellbio #Biozentrum #RNA #organelles #membranes #aging #stress #proteostasis #signaling

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Spang Lab @spanglab.bsky.social · 15d

A little stress is good for you in #health #ageing ! #Diet is important! Take a look at our article with Emmanouil Kyriakakis as 1st author!
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ

Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans

Nature Communications - Kyriakakis et al. show that bacterial RNA can improve C. elegans healthspan and reduce toxic protein aggregation in muscles. This depends on inter-tissue communication and...

rdcu.be

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Reposted by Spang Lab

HillerLab @hillerlab.bsky.social · Aug 11

We are thankful to our collaborators from the @spanglab.bsky.social and @maierlab.bsky.social @biozentrum.unibas.ch @unibas.ch

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Spang Lab @spanglab.bsky.social · Aug 15

It was our great pleasure to be part of this exciting project!

Spang Lab @spanglab.bsky.social · Jun 30

Great collaboration with Liza Malong and Filip Roudnicky from pRED @Roche rdcu.be/et6Nw

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activity

Nature Communications - Antisense oligonucleotide (ASO) cellular activity requires endosomal escape. Here, the authors show that disrupting Golgi-endosome protein AP1M1 enhances ASO activity by...

rdcu.be

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Reposted by Spang Lab

Biozentrum, University of Basel @biozentrum.unibas.ch · Mar 28

Congratulations to Anne Spang @spanglab.bsky.social for being elected as a new #AAASFellow by @aaas.org ! The world’s largest scientific society recognizes her outstanding contributions to the field of cell #biology and #biochemistry. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...

Anne Spang awarded distinction of AAAS Fellow

The AAAS has elected Prof. Anne Spang at the Biozentrum, University of Basel, as a Fellow. With this honor, the world’s largest scientific society recognizes her outstanding contributions to the field...

www.biozentrum.unibas.ch

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Spang Lab @spanglab.bsky.social · Mar 17

We got the cover!!! Check out our new story in EMBO J. #endosomes #c.elegans #membranes #GTPases

The EMBO Journal @embojournal.org · Mar 17

In issue 6:
Commentary: organoids for decoding host-microbe interactions
Importance of mitochondrial DNA elimination during spermatogenesis
How kinesin KIF12 promotes steatohepatitis
Cancer cell adaptation strategies to aneuploidy
Cover: Daniel Ott, Anne Spang et al
www.embopress.org/toc/14602075...

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Spang Lab @spanglab.bsky.social · Feb 28

Awesome lab outing: snow shoeing and sledding! Thank you for being such a wonderful team!

Spang Lab @spanglab.bsky.social · Feb 5

Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen!
www.embopress.org/doi/full/10....

Coordination between ESCRT function and Rab conversion during endosome maturation | The EMBO Journal

imageimageEarly endosome maturation requires Rab conversion and ESCRT function; however, how these processes are coordinated remains largely elusive. This study proposes that Rab conversion in both C....

www.embopress.org

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Spang Lab @spanglab.bsky.social · Jan 14

So let’s do some super science together!!

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Spang Lab @spanglab.bsky.social · Jan 14

I feel humble and honored to receive the Lelio Orci Award 2024. I want to thank my amazing co-workers and trainees who are with me on the pursuit of the understanding how intracellular communication is achieved.

Biozentrum, University of Basel @biozentrum.unibas.ch · Jan 14

Congratulations to Anne Spang for receiving the renowned Lelio Orci Award.

The award honors her pioneering work in intracellular organization and her research achievements in Cell Biology. @unibas.ch

www.biozentrum.unibas.ch/news/detail/...

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Spang Lab @spanglab.bsky.social · Nov 26

Me!