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Reposted by Stefano Crespi

Tanja Weil @weilgroup.bsky.social · Jul 24

We developed an AND-gated chemiluminescent photosensitizer that only generates light inside tumor cells, activating under 2 cancer cell-specific conditions.
Many thanks to Wenwu Peng @pengww.bsky.social from Seah Ling Kuan's group @seahling.bsky.social & our collaborators! shorturl.at/uXTg3

Autonomous Activation of a Gated Chemiluminescent Photosensitizer Enables Targeted Photodynamic Therapy in Tumor Cells

Chemiluminescence-based photodynamic therapy (CLPDT) offers a promising solution to the light penetration limits of traditional PDT. However, it lacks spatiotemporal control. Intracellularly activated...

pubs.acs.org

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Stefano Crespi @screspi.bsky.social · Jul 21

Our pipeline to compute thermal barriers of photoswitches💡 is out!🥳 We especially focused on NBDs for MOST🔋 and imines, but also stilbenes and DAEs. Try it out! You need just chemdraws and freeware to get libraries computed

doi.org/10.1002/cptc...

Semi‐Automated Pipeline for Transition State Search of Molecular Photoswitches

A semi-automated pipeline for the transition state search of molecular switches (PiTS3) is reported, which facilitates the search, optimization, and conformational analysis of transition states of ph...

doi.org

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Stefano Crespi @screspi.bsky.social · Jun 22

Almost there! :D

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Reposted by Stefano Crespi

Fredrik Schaufelberger @fschaufelberger.bsky.social · Jun 5

Over the moon that the first paper from Anja's studies on metal chelate rotaxanes is now online in @angewandtechemie.bsky.social. doi.org/10.1002/anie...
Massive congratulations Anja,
@daisypooler.bsky.social Huseyn, Monika and @screspi.bsky.social 🥳🎉🎊🍀🥃

Thread below --》

Modulation of Lanthanide Luminescence with the Mechanical Bond: Antenna‐Emitter Confinement in a Compact [2]Rotaxane

Luminescent emitters based on lanthanide ions are of ubiquitous importance in the biological sciences, but typically need sensitisation from a covalently attached adjacent chromophore – an “antenna” ....

doi.org

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Stefano Crespi @screspi.bsky.social · Apr 19

Mati's work on aldehyde and COOH effect on HTIs is out! Nice collaboration with the Ott group for the inclusion and switching of HTIs in MOFs💡 doi.org/10.1002/chem...

The Effect of Aldehyde and Carboxylic Acid Substitution on the Isomerization of Hemithioindigo Photoswitches

Hemithioindigo (HTI) photoswitches exhibit robust photoisomerization under visible light and relatively high thermal bistability. In this work, we report various modifications of the HTI core, namely....

doi.org

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Reposted by Stefano Crespi

ChemistryKoenig @chemistrykoenig.bsky.social · Jan 16

Tert-butylamine as a labile ligand and base enables cross-coupling reactions with various nucleophile classes. A great collaboration of Jonas with the Sigman lab and Gschwind group
#ChemSky #ChemCollabs #photocatalysis

doi.org/10.1021/acsc...

Cross-Coupling Reactions with Nickel, Visible Light, and tert-Butylamine as a Bifunctional Additive

Transition metal catalysis is crucial for the synthesis of complex molecules, with ligands and bases playing a pivotal role in optimizing cross-coupling reactions. Despite advancements in ligand desig...

doi.org

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Reposted by Stefano Crespi

Ivan Aprahamian @aprahamian.bsky.social · Jan 16

Reposting this #molswitch #molmachine starter pack. If you want to be included in it, please let me know
go.bsky.app/EwimNbK

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Reposted by Stefano Crespi

Matthieu Sollogoub @msollogoub.bsky.social · Jan 6

Here is a tentative Supramolecular Chemistry starter kit. Please let me know if you wish to be added ! #ChemSky
go.bsky.app/RjRgi6n

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Stefano Crespi @screspi.bsky.social · Dec 26

Great to be highlighted by @chemistryviews.bsky.social! Go pnictogen switches 😀 💡

ChemistryViews @chemistryviews.bsky.social · Dec 26

Molecular Switch with a Variety of External Triggers:
Reversible molecular switching of a phosphaethene polyaromatic hydrocarbon by irradiation, metal coordination, or deprotonation
www.chemistryviews.org/molecular-sw...

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Reposted by Stefano Crespi

ChemistryViews @chemistryviews.bsky.social · Dec 26

Molecular Switch with a Variety of External Triggers:
Reversible molecular switching of a phosphaethene polyaromatic hydrocarbon by irradiation, metal coordination, or deprotonation
www.chemistryviews.org/molecular-sw...

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Stefano Crespi @screspi.bsky.social · Dec 24

Another C=P switch💡🅿️, this time with a metal twist 😀 great collaboration with @orthaberlab.bsky.social

Orthaber Lab @orthaberlab.bsky.social · Dec 24

Latest paper on "Main group meets photochemistry" by Toma Bhowmick, Jorn Steen et al. Another mysterious phosphaalkene switch...
Collab with the @screspi.bsky.social group.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#chemsky #pisky

Reversible Metal‐Mediated Molecular Switching of a Phosphaethene Polyaromatic Hydrocarbon

This experimental and theoretical study illustrates how phosphaalkenes, which are isolobal to alkenes, can utilize a variety of external triggers for molecular switching. The E/Z isomerization of a t...

chemistry-europe.onlinelibrary.wiley.com

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Stefano Crespi @screspi.bsky.social · Dec 20

Best way to explain transient spectroscopy

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Reposted by Stefano Crespi

Steve Cranford @cranfordmatter.bsky.social · Dec 13

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Stefano Crespi @screspi.bsky.social · Dec 11

Now that @feringalab.bsky.social is here too, the race is open 😀

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Reposted by Stefano Crespi

Waser Group @lcsolab.bsky.social · Dec 5

Our OrgChem Starter Pack is growing with already 122 entries, but we will start a volume 2 if we go over the 150 limit!
go.bsky.app/NSEFPFJ

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Reposted by Stefano Crespi

Orthaber Lab @orthaberlab.bsky.social · Dec 4

Absolutely delighted to see the light of this collaborative work between the @screspi.bsky.social team and our group, with all the spectroscopy help.
Demonstrating degenerate isomerisation of phosphaalkenes using NMR spectroscopy #chemsky #NMRchat
onlinelibrary.wiley.com/doi/10.1002/...

Probing the Hidden Photoisomerization of a Symmetric Phosphaalkene Switch

In this study, we present the synthesis and analysis of a novel, air-stable, and solvent-resistant phosphaalkene switch. Using this symmetric switch, we have demonstrated degenerate photoisomerizatio...

onlinelibrary.wiley.com

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Stefano Crespi @screspi.bsky.social · Dec 4

Thank you Oliver 😊

Stefano Crespi @screspi.bsky.social · Dec 3

Hey #Chemsky! For my first post, I am hyped to share our latest efforts on main group C=P photoswitches💡, where we explored their isomerization mechanisms and observed experimentally symmetric molecules switch via NMR!🧲🔍a great international collaboration! onlinelibrary.wiley.com/doi/10.1002/...

Probing the Hidden Photoisomerization of a Symmetric Phosphaalkene Switch

In this study, we present the synthesis and analysis of a novel, air-stable, and solvent-resistant phosphaalkene switch. Using this symmetric switch, we have demonstrated degenerate photoisomerizatio...

onlinelibrary.wiley.com

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Reposted by Stefano Crespi

Harmit Singh Malik @harmitmalik.bsky.social · Nov 26

You ever have one of those amazing weeks when everything clicks in your multiple roles as an academic PI- scientist, mentor, parent, partner, colleague, psychologist, fundraiser, salesperson?

(Yeah, me neither.)

But screwing up each of these roles takes special talent.

(I am that talented.)

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Reposted by Stefano Crespi

Kjell Jorner @valencekjell.com · Nov 21

What better first post than to advertise this position. Come join our group!

Our group is recruiting a postdoctoral researcher for a project on reactive machine learning potentials. Reposts and spreading the word to interested people in your network appreciated!

jobs.ethz.ch/job/view/JOP...

Postdoc position in reactive machine learning potentials

jobs.ethz.ch

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Stefano Crespi @screspi.bsky.social · Nov 22

Oh dear lord...

Reposted by Stefano Crespi

Ivan Aprahamian @aprahamian.bsky.social · Nov 21

Here is a starter pack for folks into tiny switches and machines. I am sure I missed many. Please let me know if you should be included and I will add you
go.bsky.app/EwimNbK

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Stefano Crespi @screspi.bsky.social · Nov 21

I feel you...and the more things you have to do on top of it, the more it seems like a stressful chore where you stare at a blank page
But let's be positive! congrats on the editorial 😉

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Reposted by Stefano Crespi

Lisa Vondung @lisavondung.bsky.social · Nov 19

Would you like to spend the next summer in beautiful Hamburg doing some uranium chemistry? If you're an undergraduate student from the UK, Ireland or North America, you have 11 days left to apply for two fully funded research internships via the DAAD: www.daad.de/rise/en/rise... #chemsky

The Elbphilharmonie building in Hamburg surrounded by the Elbe river with blue skies and a few clouds.

Canal with houses and people on stand up paddling boards queuing at a waterside café

Summer day at the Alster lake in Hamburg with people on stand up paddling boards and a sailing boat

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