Rupert Faraway
@rupertfaraway.bsky.social
140 followers 210 following 12 posts
RNA biologist. Post-doc in the Plaschka and Ameres labs. PhD with Jernej Ule.
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rupertfaraway.bsky.social
If you, or anyone you know, is looking for a PhD position, I have no doubt that Ulrich's lab is a fantastic choice! I'm tempted to do a second PhD in this lab.
hohmannulrich.bsky.social
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
Reposted by Rupert Faraway
hohmannulrich.bsky.social
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
Reposted by Rupert Faraway
triggerloop.bsky.social
This is a fascinating paper that particular types of RNA binding proteins with IDRs that target nuclear speckles also can recruit their own RNAs to nuclear speckles as a negative feedback mechanism for condensation the authors call "interstasis" www.nature.com/articles/s41...
Collective homeostasis of condensation-prone proteins via their mRNAs - Nature
The authors discover a homeostatic process termed interstasis, in which an increased concentration of proteins within RNA–protein condensates induces the sequestration of their own mRNAs.
www.nature.com
Reposted by Rupert Faraway
paraspeckle.bsky.social
I am thrilled to share the first manuscript from my group on identifying sequence and structural features promoting the condensation of RNAs that are organising highly interconnected RNA networks, thereby expanding our understanding of higher-order transcriptome assemblage.
shorturl.at/pmLIj #RNASky
Integrative profiling of condensation-prone RNAs during early development
Complex RNA–protein networks play a pivotal role in the formation of many types of biomolecular condensates. How intrinsic RNA features contribute to condensate formation however remains unclear. Here...
www.biorxiv.org
rupertfaraway.bsky.social
I would rather avoid radioactivity, here.
rupertfaraway.bsky.social
Has anyone spiked in a fluorescent or clickable ATP into an in-vitro poly-adenylation reaction to label some RNA? Or anything similar (e.g. clickable nucleotide)? Preferably using E. coli PAP. I don't care if it acts as a chain terminator - that might actually be preferred.
Reposted by Rupert Faraway
nejchaberman.bsky.social
1/10
Thrilled to share our latest research on 3′UTR-derived RNAs, now published in BMC Biology! doi.org/10.1186/s129...
Here’s what we found:
rupertfaraway.bsky.social
Can MS2 loops stall reverse transcription? Does anyone know? I'm using Superscript IV at 50C.
rupertfaraway.bsky.social
All the best ideas come from staring at IGV until your eyes rot.
rupertfaraway.bsky.social
Thanks! I went and tracked it down anyway. Cool paper!
rupertfaraway.bsky.social
For me, the link doesn't work. Just a heads up! Maybe it's specific on my end, but it looks like the URL got truncated.
rupertfaraway.bsky.social
Luckily for you, Bluesky is inactive enough that it can't take up much time.
rupertfaraway.bsky.social
Do we just have to write #RNAbiology in a message to access the feed?
rupertfaraway.bsky.social
I read every Arjun Raj tweet at least 10 times, so seeing it both on BlueSky and Twitter saves me time, if anything.
rupertfaraway.bsky.social
I read that you're supposed to join feeds by posting some keyword or something? I dunno I'm boomer-pilled.
Reposted by Rupert Faraway
justingenglish.bsky.social
I'll be looking to hire another research associate (>$100k/year + benefits & retirement) shortly. Experience in molecular biology and pharmacology would be ideal, but not essential. Job ad will go up in a bit, but if anyone knows anyone looking I would be happy to chat with them.