Rene Sugar
@renesugar.bsky.social
Cargo and Biological Properties of Extracellular Vesicles Released from Human Adenovirus Type 4-Infected Lung Epithelial Cells #MECFS #LongCovid
www.mdpi.com/1999-4915/17...
www.mdpi.com/1999-4915/17...
www.mdpi.com
November 29, 2025 at 4:18 PM
Cargo and Biological Properties of Extracellular Vesicles Released from Human Adenovirus Type 4-Infected Lung Epithelial Cells #MECFS #LongCovid
www.mdpi.com/1999-4915/17...
www.mdpi.com/1999-4915/17...
Autonomic dysfunction in vitamin B12 deficiency: A heart rate variability study #MECFS #LongCovid
www.sciencedirect.com/science/arti...
"It was concluded that B12 deficiency may cause autonomic dysfunction."
www.sciencedirect.com/science/arti...
"It was concluded that B12 deficiency may cause autonomic dysfunction."
Autonomic dysfunction in vitamin B12 deficiency: A heart rate variability study
This study was arranged to examine whether vitamin B12 deficiency may cause autonomic dysfunction. Time-domain and long-term frequency-domain heart ra…
www.sciencedirect.com
November 28, 2025 at 5:28 PM
Autonomic dysfunction in vitamin B12 deficiency: A heart rate variability study #MECFS #LongCovid
www.sciencedirect.com/science/arti...
"It was concluded that B12 deficiency may cause autonomic dysfunction."
www.sciencedirect.com/science/arti...
"It was concluded that B12 deficiency may cause autonomic dysfunction."
Calprotectin, a new biomarker for diagnosis of acute respiratory infections #MECFS #LongCovid
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Calprotectin, a new biomarker for diagnosis of acute respiratory infections - Scientific Reports
Scientific Reports - Calprotectin, a new biomarker for diagnosis of acute respiratory infections
www.nature.com
November 28, 2025 at 5:08 PM
Calprotectin, a new biomarker for diagnosis of acute respiratory infections #MECFS #LongCovid
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Riboflavin as a promising antimicrobial agent? A multi-perspective review #SARSCoV2 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Riboflavin as a promising antimicrobial agent? A multi-perspective review
Riboflavin demonstrates antioxidant and photosensitizing properties. Riboflavin is able to induce ROS and modulate immune response. Riboflavin possesses potent antimicrobial activity when used alone or combined with other anti-infectives. The ...
pmc.ncbi.nlm.nih.gov
November 27, 2025 at 6:48 PM
Riboflavin as a promising antimicrobial agent? A multi-perspective review #SARSCoV2 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
NE3107 ( #bezisterim) in Adults With Neurological Symptoms of #LongCOVID (ADDRESS-LC)
clinicaltrials.gov/study/NCT068...
clinicaltrials.gov/study/NCT068...
ClinicalTrials.gov
clinicaltrials.gov
November 26, 2025 at 7:29 PM
NE3107 ( #bezisterim) in Adults With Neurological Symptoms of #LongCOVID (ADDRESS-LC)
clinicaltrials.gov/study/NCT068...
clinicaltrials.gov/study/NCT068...
Monogenic disorders of the IRF transcription factors #IEI #MECFS #LongCovid
rupress.org/jem/article/...
rupress.org/jem/article/...
November 26, 2025 at 4:26 PM
Monogenic disorders of the IRF transcription factors #IEI #MECFS #LongCovid
rupress.org/jem/article/...
rupress.org/jem/article/...
November 20, 2025 at 6:40 PM
Signs of Lyme disease that appear on your skin #MECFS #LongCovid
www.aad.org/public/disea...
"When you see signs of changing skin and symptoms: These tend to occur months or years after you are bitten by a tick."
www.aad.org/public/disea...
"When you see signs of changing skin and symptoms: These tend to occur months or years after you are bitten by a tick."
Signs of Lyme disease that appear on your skin
Learn how dermatologists identify the signs of Lyme disease on your skin.
www.aad.org
November 20, 2025 at 1:10 AM
Signs of Lyme disease that appear on your skin #MECFS #LongCovid
www.aad.org/public/disea...
"When you see signs of changing skin and symptoms: These tend to occur months or years after you are bitten by a tick."
www.aad.org/public/disea...
"When you see signs of changing skin and symptoms: These tend to occur months or years after you are bitten by a tick."
Reposted by Rene Sugar
Just heard about this huge (49 state) long covid trial using tirzepetide (aka zepbound) one of the newer glp meds. It’s run by researchers at scripps, funded by the eric & wendy schmidt foundation. It looks like it is still enrolling, fully remote participation:
longcovid.scripps.edu/locitt-t/?ut...
longcovid.scripps.edu/locitt-t/?ut...
LoCITT-T - Long COVID Treatment Trial
The Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID.
longcovid.scripps.edu
November 16, 2025 at 4:40 AM
Just heard about this huge (49 state) long covid trial using tirzepetide (aka zepbound) one of the newer glp meds. It’s run by researchers at scripps, funded by the eric & wendy schmidt foundation. It looks like it is still enrolling, fully remote participation:
longcovid.scripps.edu/locitt-t/?ut...
longcovid.scripps.edu/locitt-t/?ut...
Neuropsychiatric Manifestations of Thyroid Diseases #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Neuropsychiatric Manifestations of Thyroid Diseases
Thyroid disorders are known to cause neuropsychiatric manifestations. Various neuropsychiatric manifestations are depression, dementia, mania, and autoimmune Hashimoto encephalopathy. Numerous investigations carried out in the previous 50-60 years ...
pmc.ncbi.nlm.nih.gov
November 15, 2025 at 9:18 PM
Neuropsychiatric Manifestations of Thyroid Diseases #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health #MECFS #LongCovid
www.frontiersin.org/journals/nut...
www.frontiersin.org/journals/nut...
November 15, 2025 at 8:28 PM
Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health #MECFS #LongCovid
www.frontiersin.org/journals/nut...
www.frontiersin.org/journals/nut...
Some People With Schizophrenia May Simply Have a Vitamin Deficiency #NAPRT1
scitechdaily.com/some-people-...
scitechdaily.com/some-people-...
Some People With Schizophrenia May Simply Have a Vitamin Deficiency
A new hypothesis may hold the key to solving four medical mysteries associated with the chronic brain disorder. Four unsolved mysteries around schizophrenia have long plagued the medical community, bu...
scitechdaily.com
November 13, 2025 at 7:07 PM
Some People With Schizophrenia May Simply Have a Vitamin Deficiency #NAPRT1
scitechdaily.com/some-people-...
scitechdaily.com/some-people-...
Association between hypothyroidism and small intestinal bacterial overgrowth #SIBO #MECFS #LongCovid
pubmed.ncbi.nlm.nih.gov/17698907/
pubmed.ncbi.nlm.nih.gov/17698907/
Association between hypothyroidism and small intestinal bacterial overgrowth - PubMed
The history of overt hypothyroidism is associated with bacterial overgrowth development. Excess bacteria could influence clinical gastrointestinal manifestations. Bacterial overgrowth decontamination is associated with improved gastrointestinal symptoms. However, fermenting carbohydrate luminal bact …
pubmed.ncbi.nlm.nih.gov
November 13, 2025 at 6:05 PM
Association between hypothyroidism and small intestinal bacterial overgrowth #SIBO #MECFS #LongCovid
pubmed.ncbi.nlm.nih.gov/17698907/
pubmed.ncbi.nlm.nih.gov/17698907/
Reposted by Rene Sugar
Sydney Gesualdi was diagnosed with craniocervical instability, a rare condition that mostly affects women. After nine neurosurgeon referrals, she still can’t get surgery. She tells @namshine.bsky.social her story on an upcoming episode of (MIS)Treated. podcasts.apple.com/ca/podcast/m...
October 24, 2025 at 3:09 PM
Sydney Gesualdi was diagnosed with craniocervical instability, a rare condition that mostly affects women. After nine neurosurgeon referrals, she still can’t get surgery. She tells @namshine.bsky.social her story on an upcoming episode of (MIS)Treated. podcasts.apple.com/ca/podcast/m...
Reposted by Rene Sugar
She couldn't get diagnosed in Ontario & went to the US & was diagnosed with Craniocervical Instability, a condition that impacts mostly women. She suspects she also has Ehlers-Danlos Syndrome. Her family doctor referred her to 9 neurosurgeons and her consultations have been denied. Upcoming episode.
Sydney Gesualdi was diagnosed with craniocervical instability, a rare condition that mostly affects women. After nine neurosurgeon referrals, she still can’t get surgery. She tells @namshine.bsky.social her story on an upcoming episode of (MIS)Treated. podcasts.apple.com/ca/podcast/m...
October 24, 2025 at 3:27 PM
She couldn't get diagnosed in Ontario & went to the US & was diagnosed with Craniocervical Instability, a condition that impacts mostly women. She suspects she also has Ehlers-Danlos Syndrome. Her family doctor referred her to 9 neurosurgeons and her consultations have been denied. Upcoming episode.
Atlanto‐odontoid pyogenic arthritis revealing a Jugular Vein Thrombosis
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Atlanto‐odontoid pyogenic arthritis revealing a Jugular Vein Thrombosis
Pyogenic arthritis of the atlantoaxial joint is scarce. It can lead to several complications, such as spinal cord compression and cerebral vein thrombosis. A 51‐year‐old man presented with a twenty‐day history of inflammatory neck pain. Physical ...
pmc.ncbi.nlm.nih.gov
October 25, 2025 at 11:35 AM
Atlanto‐odontoid pyogenic arthritis revealing a Jugular Vein Thrombosis
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Matrix Metalloproteinases in Neuropathic Pain and Migraine: Friends, Enemies, and Therapeutic Targets #MMP2 #MMP9 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Matrix Metalloproteinases in Neuropathic Pain and Migraine: Friends, Enemies, and Therapeutic Targets
Matrix metalloproteinases (MMPs) constitute a family of zinc-dependent endopeptidases that mediate extracellular matrix turnover and associated processes, such as cell survival, growth, and differentiation. This paper discusses important functions ...
pmc.ncbi.nlm.nih.gov
October 23, 2025 at 4:10 PM
Matrix Metalloproteinases in Neuropathic Pain and Migraine: Friends, Enemies, and Therapeutic Targets #MMP2 #MMP9 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Rene Sugar
A new targeted therapy that degrades p300 and CBP proteins shows potential to halt prostate cancer growth by disrupting key genetic enhancers, with promising results in preclinical models. doi.org/g97jw7
Researchers find a new targeted approach to shut down prostate cancer growth
Prostate cancer relies on genetic "switches," called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers.
medicalxpress.com
October 21, 2025 at 7:41 PM
A new targeted therapy that degrades p300 and CBP proteins shows potential to halt prostate cancer growth by disrupting key genetic enhancers, with promising results in preclinical models. doi.org/g97jw7
Combination therapy of favipiravir and nitazoxanide to treat respiratory viral infections in severe T-cell deficient children: A single centre experience #MECFS #LongCovid
www.journalofinfection.com/article/S016...
www.journalofinfection.com/article/S016...
Combination therapy of favipiravir and nitazoxanide to treat respiratory viral infections in severe T-cell deficient children: A single centre experience
Balassa et al. previously reported the outcomes of antiviral treatment for RSV lower
respiratory tract infections in adults undergoing allogeneic haematopoietic cell transplantation
(HCT).1 Profoundly...
www.journalofinfection.com
October 21, 2025 at 4:12 PM
Combination therapy of favipiravir and nitazoxanide to treat respiratory viral infections in severe T-cell deficient children: A single centre experience #MECFS #LongCovid
www.journalofinfection.com/article/S016...
www.journalofinfection.com/article/S016...
Nitazoxanide, an Antiprotozoal Drug, Reduces Bone Loss in Ovariectomized Mice by Inhibition of RANKL-Induced Osteoclastogenesis #MECFS #LongCovid
www.frontiersin.org/journals/pha...
www.frontiersin.org/journals/pha...
Frontiers | Nitazoxanide, an Antiprotozoal Drug, Reduces Bone Loss in Ovariectomized Mice by Inhibition of RANKL-Induced Osteoclastogenesis
Nitazoxanide (NTZ) is an FDA-approved anti-parasitic drug with broad-spectrum anti-infective, anti-inflammatory, and antineoplastic potential. However, its r...
www.frontiersin.org
October 21, 2025 at 3:25 PM
Nitazoxanide, an Antiprotozoal Drug, Reduces Bone Loss in Ovariectomized Mice by Inhibition of RANKL-Induced Osteoclastogenesis #MECFS #LongCovid
www.frontiersin.org/journals/pha...
www.frontiersin.org/journals/pha...
Ameliorative effect of melatonin against contrast media induced renal tubular cell injury #iodixanol #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Ameliorative effect of melatonin against contrast media induced renal tubular cell injury
Background and Objective: Reactive oxygen species (ROS) is a mediator of renal damage. Melatonin is a potent-free radical scavenger. Our objective was to test whether melatonin would protect against t...
pmc.ncbi.nlm.nih.gov
October 20, 2025 at 8:49 PM
Ameliorative effect of melatonin against contrast media induced renal tubular cell injury #iodixanol #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Rene Sugar
Change needed in how we treat sepsis, says Winnipegger who nearly died from it https://www.cbc.ca/news/canada/manitoba/winnipeg-sepsis-nova-scotia-nurses-antibiotics-9.6940145
More news → CanadaHealthwatch.ca 🍁
More news → CanadaHealthwatch.ca 🍁
October 20, 2025 at 4:47 PM
Change needed in how we treat sepsis, says Winnipegger who nearly died from it https://www.cbc.ca/news/canada/manitoba/winnipeg-sepsis-nova-scotia-nurses-antibiotics-9.6940145
More news → CanadaHealthwatch.ca 🍁
More news → CanadaHealthwatch.ca 🍁
Infection of B lymphocytes by a human herpesvirus, Epstein-Barr virus, is blocked by calmodulin antagonists. #EBV #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
October 20, 2025 at 4:39 PM
Infection of B lymphocytes by a human herpesvirus, Epstein-Barr virus, is blocked by calmodulin antagonists. #EBV #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Rene Sugar
For readers interested in cancer therapies, this Review in the October issue discusses how metabolic modulators and dietary nutrients can improve the anticancer immune response and overcome drug resistance mechanisms
rdcu.be/eLS8A
www.nature.com/articles/s41...
rdcu.be/eLS8A
www.nature.com/articles/s41...
Metabolites as agents and targets for cancer immunotherapy
Nature Reviews Drug Discovery - Tumour cells undergo profound changes in their metabolism, but targeting these metabolic pathways requires understanding of the impact on immune cells as well as...
rdcu.be
October 20, 2025 at 2:47 PM
For readers interested in cancer therapies, this Review in the October issue discusses how metabolic modulators and dietary nutrients can improve the anticancer immune response and overcome drug resistance mechanisms
rdcu.be/eLS8A
www.nature.com/articles/s41...
rdcu.be/eLS8A
www.nature.com/articles/s41...