Pietro Delfino
@pietrodelfino.bsky.social
Bioinformatician in
@iannaconelab at San Raffaele Scientific Institute, Milan | Former computational biology postdoc @UniVerona.
Views my own.
@iannaconelab at San Raffaele Scientific Institute, Milan | Former computational biology postdoc @UniVerona.
Views my own.
Affinity (by Canva) is now free and so smooth compared to Illustrator
November 27, 2025 at 11:53 AM
Affinity (by Canva) is now free and so smooth compared to Illustrator
I often see statistics on road fatalities reported as deaths per capita, and Italy doesn’t come off well. But if we express it as deaths per number of registered vehicles, the picture changes, and actually looks a bit better
#sideproject
#sideproject
November 10, 2025 at 2:18 PM
I often see statistics on road fatalities reported as deaths per capita, and Italy doesn’t come off well. But if we express it as deaths per number of registered vehicles, the picture changes, and actually looks a bit better
#sideproject
#sideproject
Question for LLM experts (esp coding): We trained LLM on specific datasets at specific times. But as we rely more on LLMs, we contribute less to forums, GitHub, and other sources that once supplied training data. Could this eventually reduce training data quality and lead to worse-performing models?
October 28, 2025 at 6:34 AM
Question for LLM experts (esp coding): We trained LLM on specific datasets at specific times. But as we rely more on LLMs, we contribute less to forums, GitHub, and other sources that once supplied training data. Could this eventually reduce training data quality and lead to worse-performing models?
Reposted by Pietro Delfino
🎤 Our next episode it out!
We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection.
🎧 Listen now: https://bit.ly/4o2W8xa
We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection.
🎧 Listen now: https://bit.ly/4o2W8xa
October 21, 2025 at 5:28 PM
🎤 Our next episode it out!
We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection.
🎧 Listen now: https://bit.ly/4o2W8xa
We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection.
🎧 Listen now: https://bit.ly/4o2W8xa
Solidarietà a un grande giornalista
Due auto di proprietà del giornalista Sigfrido Ranucci sono state distrutte da un’esplosione
Due auto di proprietà del giornalista Sigfrido Ranucci sono state distrutte da un’esplosione
ilpost.link
October 17, 2025 at 6:14 AM
Solidarietà a un grande giornalista
Would be interesting to understand why is Italy there
October 12, 2025 at 8:20 AM
Would be interesting to understand why is Italy there
Reposted by Pietro Delfino
1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)
June 30, 2025 at 9:09 AM
1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)
April 18, 2025 at 6:23 PM
April 7, 2025 at 7:19 PM
Seurat’s v5 fold changes are boosted FC
March 11, 2025 at 7:32 AM
Seurat’s v5 fold changes are boosted FC
@giuliofirenze.bsky.social
Situazione curiosa in questo momento. Milano Verona Trento e Bolzano più calde di Brescia ed Emilia. A cosa è dovuto?
Situazione curiosa in questo momento. Milano Verona Trento e Bolzano più calde di Brescia ed Emilia. A cosa è dovuto?
December 24, 2024 at 9:41 AM
@giuliofirenze.bsky.social
Situazione curiosa in questo momento. Milano Verona Trento e Bolzano più calde di Brescia ed Emilia. A cosa è dovuto?
Situazione curiosa in questo momento. Milano Verona Trento e Bolzano più calde di Brescia ed Emilia. A cosa è dovuto?
decoupler-py is the only way to go.
The R version, decoupleR, is so memory-inefficient that it crashes the laptop when the python one runs in 2 minutes
The R version, decoupleR, is so memory-inefficient that it crashes the laptop when the python one runs in 2 minutes
December 4, 2024 at 3:20 PM
decoupler-py is the only way to go.
The R version, decoupleR, is so memory-inefficient that it crashes the laptop when the python one runs in 2 minutes
The R version, decoupleR, is so memory-inefficient that it crashes the laptop when the python one runs in 2 minutes
Happy to finally see this paper out! 🎉
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer - Nature Communications
Phenotypic and functional heterogeneity of cancer associated fibroblasts (CAFs) has been reported in pancreatic ductal adenocarcinoma (PDAC). Here the authors show that epithelial MAPK activity promot...
doi.org
December 4, 2024 at 10:22 AM
Happy to finally see this paper out! 🎉
doi.org/10.1038/s414...
doi.org/10.1038/s414...
What looks great to me is the option to add pvalues with a single call that both perform the test and add the values
tidyplots
Time to say goodbye to ggplot2?😜
"a significant reduction of code complexity" vs ggplot2
cran.r-project.org/web/packages...
Jan Broder Engler bioRxiv 2024
www.biorxiv.org/content/10.1...
Time to say goodbye to ggplot2?😜
"a significant reduction of code complexity" vs ggplot2
cran.r-project.org/web/packages...
Jan Broder Engler bioRxiv 2024
www.biorxiv.org/content/10.1...
November 19, 2024 at 11:38 AM
What looks great to me is the option to add pvalues with a single call that both perform the test and add the values
Humble opinion: there’s no such thing as a “standard bioinformatics analysis”.
Every experiment is different and unique, and so is every analysis.
Every experiment is different and unique, and so is every analysis.
November 17, 2024 at 4:47 PM
Humble opinion: there’s no such thing as a “standard bioinformatics analysis”.
Every experiment is different and unique, and so is every analysis.
Every experiment is different and unique, and so is every analysis.
November 15, 2024 at 5:55 AM