Patricia Bernal
@pbernalt6ss.bsky.social
Group Leader & Associate Professor of Microbiology at Universidad de Sevilla. I am interested in Microbiology, Pseudomonas putida, T6SS, biocontrol and scicomm
Website: personal.us.es/pbguzman
📍University of Seville
Website: personal.us.es/pbguzman
📍University of Seville
Pinned
Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....
Reposted by Patricia Bernal
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin...
PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...
www.findaphd.com
November 18, 2025 at 9:38 AM
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Reposted by Patricia Bernal
🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
November 20, 2025 at 8:40 PM
🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Reposted by Patricia Bernal
Two fully-funded PhD openings in my research group at the University of York.
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
A Farewell to Arms: The Trade-off Between Growth and Defence in Bacteria (York YBDTP Project) at University of York on FindAPhD.com
PhD Project - A Farewell to Arms: The Trade-off Between Growth and Defence in Bacteria (York YBDTP Project) at University of York, listed on FindAPhD.com
tiny.cc
November 27, 2025 at 5:57 PM
Two fully-funded PhD openings in my research group at the University of York.
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
Reposted by Patricia Bernal
Do you create, or are you interested in creating, educational videos, etc? If so, this article may have useful tips for you:
doi.org/10.1111/1751...
doi.org/10.1111/1751...
November 27, 2025 at 3:16 PM
Do you create, or are you interested in creating, educational videos, etc? If so, this article may have useful tips for you:
doi.org/10.1111/1751...
doi.org/10.1111/1751...
Reposted by Patricia Bernal
#MicroSky: PATHOGENS: Developed a highly sensitive, on-site CRISPR/Cas13a + MIRA system for detecting Bacillus anthracis. Detects as low as 250 copies/mL in 30 min with high specificity. Portable CRISPR point-of-care tech for rapid anthrax detection & outbreak response. doi.org/10.1111/1751...
November 27, 2025 at 11:01 AM
#MicroSky: PATHOGENS: Developed a highly sensitive, on-site CRISPR/Cas13a + MIRA system for detecting Bacillus anthracis. Detects as low as 250 copies/mL in 30 min with high specificity. Portable CRISPR point-of-care tech for rapid anthrax detection & outbreak response. doi.org/10.1111/1751...
Reposted by Patricia Bernal
In Melbourne for a symposium organized by the ARC Biofilm Research and Innovation Centre. It was really nice to be welcomed by my colleague and friend @abdou-hachani.bsky.social
November 24, 2025 at 8:09 PM
In Melbourne for a symposium organized by the ARC Biofilm Research and Innovation Centre. It was really nice to be welcomed by my colleague and friend @abdou-hachani.bsky.social
Reposted by Patricia Bernal
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 23, 2025 at 7:22 PM
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
Reposted by Patricia Bernal
#CervicalCancer could be the first cancer EVER in the world to be eliminated, if:
9️⃣0️⃣% of girls are vaccinated
7️⃣0️⃣% of women are screened
9️⃣0️⃣% of women with cervical cancer receive treatment
Learn more: bit.ly/47GIbzd #EndCervicalCancer
9️⃣0️⃣% of girls are vaccinated
7️⃣0️⃣% of women are screened
9️⃣0️⃣% of women with cervical cancer receive treatment
Learn more: bit.ly/47GIbzd #EndCervicalCancer
November 23, 2025 at 10:00 AM
#CervicalCancer could be the first cancer EVER in the world to be eliminated, if:
9️⃣0️⃣% of girls are vaccinated
7️⃣0️⃣% of women are screened
9️⃣0️⃣% of women with cervical cancer receive treatment
Learn more: bit.ly/47GIbzd #EndCervicalCancer
9️⃣0️⃣% of girls are vaccinated
7️⃣0️⃣% of women are screened
9️⃣0️⃣% of women with cervical cancer receive treatment
Learn more: bit.ly/47GIbzd #EndCervicalCancer
Reposted by Patricia Bernal
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
www.science.org
November 21, 2025 at 7:05 PM
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
Reposted by Patricia Bernal
The small amount of aluminum used in vaccines is safe.
"One study published in Vaccine found that the amount in vaccines is much smaller than what people take in every day from food and the environment."
www.voicesforvaccines.org/jtf_topics/d...
"One study published in Vaccine found that the amount in vaccines is much smaller than what people take in every day from food and the environment."
www.voicesforvaccines.org/jtf_topics/d...
Does aluminum in vaccines harm kids?
Aluminum in vaccines doesn’t build up or harm kids. Studies show it’s safe, quickly leaves the body, and doesn’t cause chronic health problems.
www.voicesforvaccines.org
November 22, 2025 at 12:31 AM
The small amount of aluminum used in vaccines is safe.
"One study published in Vaccine found that the amount in vaccines is much smaller than what people take in every day from food and the environment."
www.voicesforvaccines.org/jtf_topics/d...
"One study published in Vaccine found that the amount in vaccines is much smaller than what people take in every day from food and the environment."
www.voicesforvaccines.org/jtf_topics/d...
Reposted by Patricia Bernal
"Aluminum is sometimes added to vaccines as an adjuvant, to help the body’s immune system respond better. This means children need fewer doses to get full protection."
www.voicesforvaccines.org/jtf_topics/i...
www.voicesforvaccines.org/jtf_topics/i...
Is aluminum in vaccines safe?
A closer look at the science behind aluminum in vaccines shows it’s safe, well-studied, and used in tiny amounts that don’t pose health risks to children.
www.voicesforvaccines.org
November 22, 2025 at 5:56 PM
"Aluminum is sometimes added to vaccines as an adjuvant, to help the body’s immune system respond better. This means children need fewer doses to get full protection."
www.voicesforvaccines.org/jtf_topics/i...
www.voicesforvaccines.org/jtf_topics/i...
Reposted by Patricia Bernal
Apply now for EMBO Workshop "Evolving together: From #genomics to biological interactions" in Taipei, Taiwan, 24–27 Apr 2026.
Abstract submission/Registration deadline: 20 Jan/28 Feb 2026
meetings.embo.org/event/26-bio...
#EMBOEvoGenBio #GeneSky #EvoSky #EcoSky #EMBOevents 🧪
Abstract submission/Registration deadline: 20 Jan/28 Feb 2026
meetings.embo.org/event/26-bio...
#EMBOEvoGenBio #GeneSky #EvoSky #EcoSky #EMBOevents 🧪
Evolving together: from genomics to biological interactions
Genomic and evolutionary research has transformed our understanding of how biological interactions shape life’s diversity. From symbiosis and host–pathogen relationships to competition, cooperation, …
meetings.embo.org
November 14, 2025 at 10:39 AM
Apply now for EMBO Workshop "Evolving together: From #genomics to biological interactions" in Taipei, Taiwan, 24–27 Apr 2026.
Abstract submission/Registration deadline: 20 Jan/28 Feb 2026
meetings.embo.org/event/26-bio...
#EMBOEvoGenBio #GeneSky #EvoSky #EcoSky #EMBOevents 🧪
Abstract submission/Registration deadline: 20 Jan/28 Feb 2026
meetings.embo.org/event/26-bio...
#EMBOEvoGenBio #GeneSky #EvoSky #EcoSky #EMBOevents 🧪
Reposted by Patricia Bernal
Time to rethink prevailing views re regulations on GE & SynBio microbes for env bioremediation in an era of climate change. We must move from a mindset of control & domination to one of stewardship & negotiation. Indigenous perspectives can help in bridging the artificial–natural divide. Stay tuned!
November 21, 2025 at 10:20 AM
Time to rethink prevailing views re regulations on GE & SynBio microbes for env bioremediation in an era of climate change. We must move from a mindset of control & domination to one of stewardship & negotiation. Indigenous perspectives can help in bridging the artificial–natural divide. Stay tuned!
Reposted by Patricia Bernal
A pleasure and an honour to have received this prestigious grant with my admired colleagues and friends @sanmillan.bsky.social and @asanchezlab.bsky.social . More about AMR under plasmid lens!. My sincere gratitude to @caixaresearch.bsky.social
@microryc.bsky.social @esgem-sg.bsky.social
@microryc.bsky.social @esgem-sg.bsky.social
November 21, 2025 at 5:19 AM
A pleasure and an honour to have received this prestigious grant with my admired colleagues and friends @sanmillan.bsky.social and @asanchezlab.bsky.social . More about AMR under plasmid lens!. My sincere gratitude to @caixaresearch.bsky.social
@microryc.bsky.social @esgem-sg.bsky.social
@microryc.bsky.social @esgem-sg.bsky.social
Reposted by Patricia Bernal
Team fish - we need your help! We are trying to build a database of all the fish chromosome-scale genomes where sex chromosomes have been identified. Have you build one or some? Do you know someone who has? Can you post the link in the comments? Please spread the word and repost! Thank you!
November 20, 2025 at 4:44 PM
Team fish - we need your help! We are trying to build a database of all the fish chromosome-scale genomes where sex chromosomes have been identified. Have you build one or some? Do you know someone who has? Can you post the link in the comments? Please spread the word and repost! Thank you!
Reposted by Patricia Bernal
🚀New preprint from our lab!
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
November 20, 2025 at 6:52 PM
🚀New preprint from our lab!
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡
Continue reading (🧵)
Reposted by Patricia Bernal
#MicroSky: Wiley is bringing its microbiology journals together under Wiley Life Sciences, follow us on Bluesky for updates, highlights and community insigts @wileylifesci.bsky.social
November 20, 2025 at 2:27 PM
#MicroSky: Wiley is bringing its microbiology journals together under Wiley Life Sciences, follow us on Bluesky for updates, highlights and community insigts @wileylifesci.bsky.social
Reposted by Patricia Bernal
Everything you need to explain AMR to family and friends-14:
@pablolaborda.bsky.social
@crisherencias.bsky.social
@pharmageddon.bsky.social
@ecdc.europa.eu
@eberllab.bsky.social
@klebclub.bsky.social
@gcagatgcaatg.bsky.social
AMR and the environment
imili.org/pdf/Antibiot...
@pablolaborda.bsky.social
@crisherencias.bsky.social
@pharmageddon.bsky.social
@ecdc.europa.eu
@eberllab.bsky.social
@klebclub.bsky.social
@gcagatgcaatg.bsky.social
AMR and the environment
imili.org/pdf/Antibiot...
November 20, 2025 at 9:41 AM
Everything you need to explain AMR to family and friends-14:
@pablolaborda.bsky.social
@crisherencias.bsky.social
@pharmageddon.bsky.social
@ecdc.europa.eu
@eberllab.bsky.social
@klebclub.bsky.social
@gcagatgcaatg.bsky.social
AMR and the environment
imili.org/pdf/Antibiot...
@pablolaborda.bsky.social
@crisherencias.bsky.social
@pharmageddon.bsky.social
@ecdc.europa.eu
@eberllab.bsky.social
@klebclub.bsky.social
@gcagatgcaatg.bsky.social
AMR and the environment
imili.org/pdf/Antibiot...
Reposted by Patricia Bernal
Happy to share our latest T6SS review:
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
The type VI secretion system and associated effector proteins - Nature Reviews Microbiology
In this Review, Basler and colleagues examine the type VI secretion system (T6SS), focusing on the diversity of antibacterial T6SS effectors and the evolutionary forces that shape them. They explain h...
nature.com
November 17, 2025 at 10:08 AM
Happy to share our latest T6SS review:
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
nature.com/articles/s41...
Thank you, Jan, Danny (@dannyjamesward.bsky.social), Joana (@joanampereira.bsky.social), as well as reviewers and editors @natrevmicro.nature.com!
Reposted by Patricia Bernal
How Bacteria Outsmart Plants—Then Flee the Scene!
#MicroSky #PlantScience #Pseudomonas
Our new research in Nature Microbiology uncovers the sophisticated teamwork of Pseudomonas syringae, a notorious plant pathogen.
🔗 rdcu.be/egczU
#MicroSky #PlantScience #Pseudomonas
Our new research in Nature Microbiology uncovers the sophisticated teamwork of Pseudomonas syringae, a notorious plant pathogen.
🔗 rdcu.be/egczU
Pseudomonas syringae subpopulations cooperate by coordinating flagellar and type III secretion spatiotemporal dynamics to facilitate plant infection
Nature Microbiology - Single-cell gene expression analysis reveals phenotypic heterogeneity to enable bacterial specialization over the course of plant colonization.
rdcu.be
April 3, 2025 at 2:52 PM
How Bacteria Outsmart Plants—Then Flee the Scene!
#MicroSky #PlantScience #Pseudomonas
Our new research in Nature Microbiology uncovers the sophisticated teamwork of Pseudomonas syringae, a notorious plant pathogen.
🔗 rdcu.be/egczU
#MicroSky #PlantScience #Pseudomonas
Our new research in Nature Microbiology uncovers the sophisticated teamwork of Pseudomonas syringae, a notorious plant pathogen.
🔗 rdcu.be/egczU
Reposted by Patricia Bernal
🚨 PhD Opportunity 🚨
Interested in microbiology, phages & water security?
Join me and Prof Cindy Smith to test phages as a sustainable alternative to chlorine in drinking-water biofilters.
Metagenomics, phage discovery & ecology — all in one exciting project!
Apply: www.gla.ac.uk/colleges/mvl...
Interested in microbiology, phages & water security?
Join me and Prof Cindy Smith to test phages as a sustainable alternative to chlorine in drinking-water biofilters.
Metagenomics, phage discovery & ecology — all in one exciting project!
Apply: www.gla.ac.uk/colleges/mvl...
November 15, 2025 at 3:30 PM
🚨 PhD Opportunity 🚨
Interested in microbiology, phages & water security?
Join me and Prof Cindy Smith to test phages as a sustainable alternative to chlorine in drinking-water biofilters.
Metagenomics, phage discovery & ecology — all in one exciting project!
Apply: www.gla.ac.uk/colleges/mvl...
Interested in microbiology, phages & water security?
Join me and Prof Cindy Smith to test phages as a sustainable alternative to chlorine in drinking-water biofilters.
Metagenomics, phage discovery & ecology — all in one exciting project!
Apply: www.gla.ac.uk/colleges/mvl...
Reposted by Patricia Bernal
Happy to share the last paper form the lab:
Specialized shuttle proteins recognize
T9SS signals and target
effectors to their final destinations. Great work by @maellepllt.bsky.social, led by @thicoz.bsky.social in collaboration with @audebertstephane.bsky.social
www.nature.com/articles/s42...
Specialized shuttle proteins recognize
T9SS signals and target
effectors to their final destinations. Great work by @maellepllt.bsky.social, led by @thicoz.bsky.social in collaboration with @audebertstephane.bsky.social
www.nature.com/articles/s42...
Specialized shuttle proteins recognize Type IX secretion signals and target effectors to their final destinations in Flavobacterium johnsoniae
Communications Biology - Bacteroidota use the Type IX secretion system to secrete proteins with a conserved C-terminal domain (CTD) secretion signal domain. Type B CTDs require specific shuttle...
www.nature.com
November 15, 2025 at 3:55 PM
Happy to share the last paper form the lab:
Specialized shuttle proteins recognize
T9SS signals and target
effectors to their final destinations. Great work by @maellepllt.bsky.social, led by @thicoz.bsky.social in collaboration with @audebertstephane.bsky.social
www.nature.com/articles/s42...
Specialized shuttle proteins recognize
T9SS signals and target
effectors to their final destinations. Great work by @maellepllt.bsky.social, led by @thicoz.bsky.social in collaboration with @audebertstephane.bsky.social
www.nature.com/articles/s42...
Reposted by Patricia Bernal
Reposted by Patricia Bernal
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
November 14, 2025 at 6:38 PM
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Reposted by Patricia Bernal
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
November 9, 2025 at 5:20 PM
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!