Paolo De Los Rios
@paolodelosrios.bsky.social
Biophysicist/Statistical physicist, Protein Quality Control / proteostasis (chaperones galore), energy-driven processes in the cell, machine learning/AI for proteins, and origins of life @EPFL, Lausanne.
Opinions are mine.
#SempreForzaToro
Opinions are mine.
#SempreForzaToro
Like 30 seconds earlier
November 28, 2025 at 7:15 AM
Like 30 seconds earlier
Good morning
November 28, 2025 at 7:13 AM
Good morning
Reposted by Paolo De Los Rios
Three German universities offering post-docs for researchers "who cannot conduct or continue their work in the USA appropriately because of actual political pressure. "
www.uni-konstanz.de/zukunftskoll...
www.uni-konstanz.de/zukunftskoll...
Early Career Rescue Fellowship
www.uni-konstanz.de
November 11, 2025 at 7:10 PM
Three German universities offering post-docs for researchers "who cannot conduct or continue their work in the USA appropriately because of actual political pressure. "
www.uni-konstanz.de/zukunftskoll...
www.uni-konstanz.de/zukunftskoll...
Good news!
Now invest more instead of cutting, on both sides!
(Of course I have a conflict of interest being a scientist 😉)
Now invest more instead of cutting, on both sides!
(Of course I have a conflict of interest being a scientist 😉)
Switzerland is joining Horizon Europe!
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
We are uniting two research powerhouses.
For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more.
Today is a good day for science, and for our EU-Switzerland partnership.
November 11, 2025 at 11:21 AM
Good news!
Now invest more instead of cutting, on both sides!
(Of course I have a conflict of interest being a scientist 😉)
Now invest more instead of cutting, on both sides!
(Of course I have a conflict of interest being a scientist 😉)
Fantastic opportunity!
Great project with a great PI.
A no-miss opportunity
Great project with a great PI.
A no-miss opportunity
Postdoctoral position in the team of Alessandro Barducci in the CBS, focusing on multiscale simulations of RNA-driven condensates, with applications in synthetic biology.
More information :
www.cbs.cnrs.fr/images/jobs/...
The position is expected to start in early 2026, with some flexibility.
More information :
www.cbs.cnrs.fr/images/jobs/...
The position is expected to start in early 2026, with some flexibility.
November 7, 2025 at 4:33 PM
Fantastic opportunity!
Great project with a great PI.
A no-miss opportunity
Great project with a great PI.
A no-miss opportunity
Early afternoon
October 28, 2025 at 12:31 PM
Early afternoon
After the rain
October 4, 2025 at 7:50 PM
After the rain
Immortal
Friday was the 50th anniversary of the The Rocky Horror Picture Show release, which bombed at the time but quickly became perhaps the biggest, most durable cult classic in history, spanning generations in appeal.
So, let's do the time warp again, folks!
www.washingtonpost.com/entertainmen...
So, let's do the time warp again, folks!
www.washingtonpost.com/entertainmen...
a close up of a woman 's face with the words how bout that written below her
Alt: a close up of a man 's face with the words how bout that written below him - Frankfurter played by Tim Curry from Rocky Horror, released 9/26/75
media.tenor.com
September 28, 2025 at 8:20 PM
Immortal
Reposted by Paolo De Los Rios
Je lance donc la suite de #lesmétazoairesdupèreconnard après la grande musaraigne.
Cela sera des formats courts juste pour présenter un métazoaire un peu rigolo / étrange / spécial.
Aujourd'hui Heterocephalus glaber, dit le Rat-taupe nu. De l'Ordre des Rodentia et du sous-ordre des Hystricomorpha.
Cela sera des formats courts juste pour présenter un métazoaire un peu rigolo / étrange / spécial.
Aujourd'hui Heterocephalus glaber, dit le Rat-taupe nu. De l'Ordre des Rodentia et du sous-ordre des Hystricomorpha.
September 28, 2025 at 6:31 PM
Je lance donc la suite de #lesmétazoairesdupèreconnard après la grande musaraigne.
Cela sera des formats courts juste pour présenter un métazoaire un peu rigolo / étrange / spécial.
Aujourd'hui Heterocephalus glaber, dit le Rat-taupe nu. De l'Ordre des Rodentia et du sous-ordre des Hystricomorpha.
Cela sera des formats courts juste pour présenter un métazoaire un peu rigolo / étrange / spécial.
Aujourd'hui Heterocephalus glaber, dit le Rat-taupe nu. De l'Ordre des Rodentia et du sous-ordre des Hystricomorpha.
Reposted by Paolo De Los Rios
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
September 26, 2025 at 3:35 PM
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
‘Nuf said
I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)
September 25, 2025 at 5:28 AM
‘Nuf said
They claim that 1) tariffs will pay for the tax cut and 2) tariffs will move production to the US.
Once production is back to the US, how will the lower income from tariffs pay for the tax cut?
edition.cnn.com/2025/09/15/p...
Once production is back to the US, how will the lower income from tariffs pay for the tax cut?
edition.cnn.com/2025/09/15/p...
Analysis: Trump’s tariffs are bigger than his tax cuts for most Americans | CNN Politics
Republicans and President Donald Trump want credit for what he has called “the largest tax cut in the history of our country” for the income tax cuts in his One Big Beautiful Bill Act.
edition.cnn.com
September 15, 2025 at 12:19 PM
They claim that 1) tariffs will pay for the tax cut and 2) tariffs will move production to the US.
Once production is back to the US, how will the lower income from tariffs pay for the tax cut?
edition.cnn.com/2025/09/15/p...
Once production is back to the US, how will the lower income from tariffs pay for the tax cut?
edition.cnn.com/2025/09/15/p...
Here we are, trying to teach an old, but always fantastic dog (Direct Coupling Analysis) some new tricks! It learns them pretty well.
Together with @fcaredda.bsky.social @lgennai.bsky.social and bluesky-absent Andrea Pagnani.
www.biorxiv.org/content/10.1...
Together with @fcaredda.bsky.social @lgennai.bsky.social and bluesky-absent Andrea Pagnani.
www.biorxiv.org/content/10.1...
Controllable Protein Design via Autoregressive Direct Coupling Analysis Conditioned on Principal Components
We present FeatureDCA, a statistical framework for protein sequence modeling and generation that extends Direct Coupling Analysis (DCA) with biologically meaningful conditioning. The method can levera...
www.biorxiv.org
August 22, 2025 at 3:34 PM
Here we are, trying to teach an old, but always fantastic dog (Direct Coupling Analysis) some new tricks! It learns them pretty well.
Together with @fcaredda.bsky.social @lgennai.bsky.social and bluesky-absent Andrea Pagnani.
www.biorxiv.org/content/10.1...
Together with @fcaredda.bsky.social @lgennai.bsky.social and bluesky-absent Andrea Pagnani.
www.biorxiv.org/content/10.1...
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)
The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...
tinyurl.com
August 21, 2025 at 6:35 AM
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
Walking up beautiful Swiss mountains and talking protein homeostasis (among other things) with good friend and colleague Pierre Goloubinoff
August 18, 2025 at 5:45 PM
Walking up beautiful Swiss mountains and talking protein homeostasis (among other things) with good friend and colleague Pierre Goloubinoff
Who said “friends” and entered?
Should I follow?
Should I follow?
August 18, 2025 at 5:41 PM
Who said “friends” and entered?
Should I follow?
Should I follow?
what a marvel
August 14, 2025 at 5:42 AM
what a marvel
Reposted by Paolo De Los Rios
This programme is ideal for professional development (incl a budget for that) and comes with a competitive package - make sure to check it out
#Postdoc – #ExcellenceByChoice programme!
Our lab & the Kohler Mito lab are seeking researchers to study specialized mitoribosomes under stress & ageing.
Apply by Aug 17
👉https://www.vkohler-lab.com/join-our-team
#ExcellenceByChoice #Mitochondria #Ageing #Proteostasis
Our lab & the Kohler Mito lab are seeking researchers to study specialized mitoribosomes under stress & ageing.
Apply by Aug 17
👉https://www.vkohler-lab.com/join-our-team
#ExcellenceByChoice #Mitochondria #Ageing #Proteostasis
July 30, 2025 at 8:25 PM
This programme is ideal for professional development (incl a budget for that) and comes with a competitive package - make sure to check it out
New paper from the lab (kudos to @chercheurjuteux.com , Fauvet and to Pierre Goloubinoff).
Possibly we raise more questions than we answer, but it has been inspiring.
Hopefully we’ll come up with the theory shortly… it is in the works.
www.jbc.org/article/S002...
Possibly we raise more questions than we answer, but it has been inspiring.
Hopefully we’ll come up with the theory shortly… it is in the works.
www.jbc.org/article/S002...
Redirecting
kwnsfk27.r.eu-west-1.awstrack.me
July 22, 2025 at 10:39 PM
New paper from the lab (kudos to @chercheurjuteux.com , Fauvet and to Pierre Goloubinoff).
Possibly we raise more questions than we answer, but it has been inspiring.
Hopefully we’ll come up with the theory shortly… it is in the works.
www.jbc.org/article/S002...
Possibly we raise more questions than we answer, but it has been inspiring.
Hopefully we’ll come up with the theory shortly… it is in the works.
www.jbc.org/article/S002...
June 24, 2025 at 12:23 PM
Reposted by Paolo De Los Rios
Come work with me an Sarah and become a part of DDLS danaher.wd1.myworkdayjobs.com/CytivaJobsPP...
Industry PhD position in Computational Protein Design
We are looking for a motivated PhD student to join us in a unique, collaborative project between our Affinity Ligand Design team at Cytiva and the Elofsson group at Stockholm University, where we will...
danaher.wd1.myworkdayjobs.com
May 26, 2025 at 6:56 AM
Come work with me an Sarah and become a part of DDLS danaher.wd1.myworkdayjobs.com/CytivaJobsPP...