Iantrek launched AlloFlo Uveo, a bio-interventional surgical treatment that targets the uveoscleral pathway in patients with glaucoma, according to a press release. “Over the past 15 years, glaucoma surgeons have seen dozens of technologies become available for enhancing the trabecular outflow pathway,” Adam Szaronos, CEO of Iantrek, told Healio. “But as we all know, the eye has two natural outflow pathways. This is where the biggest unmet need is and is a complementary fit for every MIGS patient as efficacy inevitably wanes. AlloFlo Uveo provides a reproducible way to access the uveoscleral

There was a lot of excitement when teprotumumab-trbw became the first drug approved for the treatment of thyroid eye disease in January 2020. The availability of teprotumumab-trbw (Tepezza, Amgen) has changed the landscape of treatment in thyroid eye disease. Image: Eisha Gupta, MD. Printed with permission. “Tepezza has been a game changer in how thyroid eye disease is now managed,” Arti Bhan, MD, FACE, a Healio | Endocrine Today Editorial Board Member and division head of endocrinology at Henry Ford Health System, said in an interview. “We have patients who have high clinical activity scores

Iantrek launched AlloFlo Uveo, a bio-interventional surgical treatment that targets the uveoscleral pathway in patients with glaucoma, according to a press release. “Over the past 15 years, glaucoma surgeons have seen dozens of technologies become available for enhancing the trabecular outflow pathway,” Adam Szaronos, CEO of Iantrek, told Healio. “But as we all know, the eye has two natural outflow pathways. This is where the biggest unmet need is and is a complementary fit for every MIGS patient as efficacy inevitably wanes. AlloFlo Uveo provides a reproducible way to access the uveoscleral

Eye, Published online: 15 October 2025; doi:10.1038/s41433-025-04079-4A 20-year review of orbital biopsy at the Newcastle Eye Centre

We hypothesised that HM patients would exhibit impaired emotional processing capabilities due to disrupted amygdala connectivity

A retrospective study found significant value in reducing the time to repair of ocular injuries sustained during battle among US military members.

Publication date: Available online 15 October 2025 Source: Experimental Eye Research Author(s): Dongchun Xie, Jiahui Wang, Li Huang, Zhihong Zhao, Ronggen Wang, Haibin Long, Qingchun Ni, Haiying Liu, Minhua Hu, Junjiu Huang

Publication date: Available online 15 October 2025 Source: Experimental Eye Research Author(s): Manqi Pan, Zihao Chen, Xueliang Pan, He Zhang, Matthew Reilly, Sayoko E. Moroi, Jun Liu

Publication date: Available online 12 October 2025 Source: AJO International Author(s): Konstantinos G. Baroutis, Gustavo Sakuno, Sandra Hoyek, Nimesh A. Patel, Joan W. Miller, Demetrios G. Vavvas

.

Response to Letter in regards to Efficacy and Safety of Intravitreal Brolucizumab in Chronic Central Serous Chorioretinopathy: A Retrospective Cohort Study [Letter]

Corrigendum for the article The Correlation Between Macular Vessel Density and Its Clinical Parameters in Diabetes Mellitus Type 2

Punctate inner choroidopathy (PIC) and idiopathic multifocal choroiditis (MFC) are inflammatory ocular disorders, which typically occur in young women without any other systemic associated disease1,2. PIC and MFC are classified as ‘white dot syndromes’, characterized by multiple, yellowish inflammatory lesions in the posterior pole or periphery3. While PIC lesions are typically more confined to the posterior pole in the absence of intraocular inflammation (IOI), MFC lesions may extend to the periphery and are more often associated with IOI and panuveitis4.

We thank Nishida et al for their thoughtful comments regarding our study and appreciate the opportunity to respond. First, we would like to address the timing of preoperative hemoglobin A1c (HbA1c). Nishida et al express reservations about our use of HbA1c measurements in the 0- to 6-month time period before cataract surgery and suggest that these measurements may not accurately reflect perioperative glycemic control. In response, we direct the authors’ attention to our study subanalysis of patients with HbA1c drawn 0 to 2 months before cataract surgery (n = 95 084, Tables 2 and 4 in the original article).

Little is known about how medication adherence is related to longitudinal structural and functional loss. Here, we investigate the associations between medication adherence with mean intraocular pressure (IOP) measurements, explore whether adherence predicts rates of change in mean deviation (MD) and retinal nerve fiber layer thickness (RNFLT), and identify factors associated with worse adherence using a large sample of glaucoma and glaucoma suspect eyes.

To evaluate the prevalence, surgical trends, and economic burden of cataract among Medicare beneficiaries aged 65 and older in the United States.

Patients with high myopia had less favorable refractive results after LASIK but still had satisfactory short-term outcomes, according to a study published in Journal of Refractive Surgery. Adir Sommer, MD, of the department of ophthalmology, Rambam Health Care Campus, Israel, and colleagues said that there are recognized differences in visual and refractive LASIK outcomes between patients with low and high myopia. “By conducting this large-scale comparative study, we aimed to generate robust, statistically adjusted insights that could aid in refining patient selection, surgical planning and

Patients with high myopia had less favorable refractive results after LASIK but still had satisfactory short-term outcomes, according to a study published in Journal of Refractive Surgery. Adir Sommer, MD, of the department of ophthalmology, Rambam Health Care Campus, Israel, and colleagues said that there are recognized differences in visual and refractive LASIK outcomes between patients with low and high myopia. “By conducting this large-scale comparative study, we aimed to generate robust, statistically adjusted insights that could aid in refining patient selection, surgical planning and

A systematic literature review studied the efficacy and safety of teprotumumab, tocilizumab, and rituximab for the treatment of thyroid eye disease (TED).

The Trump administration has reinstated hundreds of CDC staffers who were mistakenly laid off last week due to what an HHS official confirmed to Healio was a “glitch in the system.” Among the reinstated employees were officers in the CDC’s famed Epidemic Intelligence Service (EIS), employees working on the U.S. measles response and the Ebola virus outbreak in the Democratic Republic of the Congo, and staffers who run the Morbidity and Mortality Weekly Report, a journal known as “the voice of the CDC,” the official confirmed. The employees had received reduction-in-force (RIF) notices on Oct.

The Trump administration has reinstated hundreds of CDC staffers who were mistakenly laid off last week due to what an HHS official confirmed to Healio was a “glitch in the system.” Among the reinstated employees were officers in the CDC’s famed Epidemic Intelligence Service (EIS), employees working on the U.S. measles response and the Ebola virus outbreak in the Democratic Republic of the Congo, and staffers who run the Morbidity and Mortality Weekly Report, a journal known as “the voice of the CDC,” the official confirmed. The employees had received reduction-in-force (RIF) notices on Oct.

As presbyopia becomes a more common concern among patients in their 40s and beyond, the way we approach intake and early patient engagement must evolve to meet their changing needs. Many of these individuals are not ready for — or not interested in — surgical options, and some are hesitant to rely on reading glasses. With the introduction of presbyopia drops, we have found new opportunities to support these patients, but doing so effectively requires thoughtful changes to how we identify needs and introduce options. Here is a practical three-step strategy for evolving intake

Background/aims To investigate the biomechanical mechanisms underlying the occurrence of optic disc haemorrhage (ODH) in glaucoma by analysing the stress at the lamina cribrosa (LC)-sclera interface using patient-specific finite element models based on clinical data.Methods This was a retrospective, single-centre, simulation-based, case-control study. Finite element simulations were conducted on individualised optic nerve head models under two gaze conditions: primary gaze and 10° ocular rotation (adduction). The von Mises stress was calculated at the anterior and posterior boundaries of the LC-sclera interface. Intergroup differences in stress and their association with clinical variables were evaluated using analysis of variance, correlation and regression analyses.Results A total of 111 eyes were included: 44 eyes with primary open-angle glaucoma (POAG) and ODH, 34 eyes with POAG without ODH and 33 control eyes. We found statistically significant differences in stress at both the anterior and posterior boundaries during adduction between the POAG with ODH group and the other groups (p

Purpose To assess the relationship between accommodative lag (defocus) and accommodative response to determine which drives emmetropisation in highly farsighted 3-month-old infants who successfully reached emmetropia in a 15-month period.Materials and methods 35 highly hyperopic (≥+5.00 D most hyperopic meridian) 3-month-old infants (57% female) were enrolled in a clinical trial (NCT03669146) to determine the effect on emmetropisation (reaching

Objective Blindness, a significant complication of neonatal disorders (ND) and their four subtypes, profoundly impacts individuals’ quality of life. This study assesses the global burden of blindness caused by ND to inform health policy development.Methods Data were obtained from the Global Burden of Disease Study 2021 (GBD 2021). Age-standardised prevalence and years lived with disability (YLDs) were analysed using estimated annual percentage changes (EAPCs) and joinpoint model. Health disparities were evaluated through Sociodemographic Index (SDI) via the Slope Index of Inequality (SII) and Concentration Index (CI). Decomposition analysis identified burden changes, and Bayesian age-period-cohort (BAPC) models projected trends through 2040.Results In 2021, global ND-related blindness cases exceeded 4.26 million, reflecting a 60.92% increase in prevalence and 61.33% rise in YLDs since 1990. Age-standardised prevalence rates (ASPR) and YLDs rates (ASYR) increased, with the EAPCs of 0.29 (95% CI 0.26 to 0.32) and 0.31 (95% CI 0.28 to 0.34), respectively, primarily driven by population growth and epidemiological change. Socioeconomic disparities persisted, with higher burdens in lower SDI regions. From 2005 to 2021, prevalence peaked in the 45–54 age group. Projections to 2040 indicated contrasting trends: a decline in prevalence based on 1990–2021 trends, but a slight increase based on 1990–2019 trends, prior to the COVID-19 pandemic.Conclusions The burden of ND-related blindness remains substantial. The heavier burden in low SDI regions and the delayed onset of blindness due to the cumulative effects of ND may be underestimated. Urgent improvements in medical resource allocation and long-term eye health follow-up for ND survivors are needed.