Nick George
@nickgeorge.net
Scientific consultant. Digging into pharma and biotech industry data
JPM Healthcare opening day is the most disclosure-heavy day in biotech. rxdatalab.com/research/jpm... #biotech #sec
January 19, 2026 at 3:52 PM
JPM Healthcare opening day is the most disclosure-heavy day in biotech. rxdatalab.com/research/jpm... #biotech #sec
there are many SEC form parsers, this one is mine nickgeorge.net/sec-parser/
Simple and Efficient SEC Filing Parsing Using Go
A lightweight Go library and CLI for downloading and parsing SEC filings, built for speed, minimal dependencies, and extracting exactly the data I care about.
nickgeorge.net
December 30, 2025 at 4:44 PM
there are many SEC form parsers, this one is mine nickgeorge.net/sec-parser/
I came across this method for checking for new SEC filings before the SEC updates their index/RSS pages, very clever!
www.reddit.com/r/quant/comm...
Code: github.com/john-friedma...
www.reddit.com/r/quant/comm...
Code: github.com/john-friedma...
December 30, 2025 at 1:46 PM
I came across this method for checking for new SEC filings before the SEC updates their index/RSS pages, very clever!
www.reddit.com/r/quant/comm...
Code: github.com/john-friedma...
www.reddit.com/r/quant/comm...
Code: github.com/john-friedma...
Claude Code is fantastic, but you have to pay attention! I just caught it string concatenating a query and 'escaping' with this little function:
// escapes single quotes in SQL strings
func escapeSQL(s string) string {
return strings.ReplaceAll(s, "'", "''")
}
These are tools for experts
// escapes single quotes in SQL strings
func escapeSQL(s string) string {
return strings.ReplaceAll(s, "'", "''")
}
These are tools for experts
November 8, 2025 at 6:41 PM
Claude Code is fantastic, but you have to pay attention! I just caught it string concatenating a query and 'escaping' with this little function:
// escapes single quotes in SQL strings
func escapeSQL(s string) string {
return strings.ReplaceAll(s, "'", "''")
}
These are tools for experts
// escapes single quotes in SQL strings
func escapeSQL(s string) string {
return strings.ReplaceAll(s, "'", "''")
}
These are tools for experts
LLMs in data pipelines? Use strategically.
I used GPT-4o for ONE step in my clinical trial harmonization pipeline.
Everything else stayed deterministic.
Result: 89% automation, zero catastrophic errors.
rxdatalab.com/blog/llm-dat...
#DataEngineering #LLM #ProductionAI #DataStrategy #Bio
I used GPT-4o for ONE step in my clinical trial harmonization pipeline.
Everything else stayed deterministic.
Result: 89% automation, zero catastrophic errors.
rxdatalab.com/blog/llm-dat...
#DataEngineering #LLM #ProductionAI #DataStrategy #Bio
How I Use LLMs for Data Harmonization: A Strategic, Limited Approach
A technical walkthrough of how I used LLMs strategically to improve name harmonization for clinical trial sponsors while minimizing non-determinism.
rxdatalab.com
August 4, 2025 at 2:25 PM
LLMs in data pipelines? Use strategically.
I used GPT-4o for ONE step in my clinical trial harmonization pipeline.
Everything else stayed deterministic.
Result: 89% automation, zero catastrophic errors.
rxdatalab.com/blog/llm-dat...
#DataEngineering #LLM #ProductionAI #DataStrategy #Bio
I used GPT-4o for ONE step in my clinical trial harmonization pipeline.
Everything else stayed deterministic.
Result: 89% automation, zero catastrophic errors.
rxdatalab.com/blog/llm-dat...
#DataEngineering #LLM #ProductionAI #DataStrategy #Bio
Sad news about #23andMe. A few months ago I wrote a piece suggesting the #NIH buy the company or assets. Even given the new administration, I'd still prefer the data is publicly owned rather than sold for parts to the highest bidder.
nickgeorge.net/nih-should-b...
nickgeorge.net/nih-should-b...
NIH Should Buy 23andMe
23andMe revolutionized genetic testing, building a database of over 15 million genotypes for research. However, the company now faces significant financial and legal challenges, casting doubt on its f...
nickgeorge.net
March 24, 2025 at 12:53 PM
Sad news about #23andMe. A few months ago I wrote a piece suggesting the #NIH buy the company or assets. Even given the new administration, I'd still prefer the data is publicly owned rather than sold for parts to the highest bidder.
nickgeorge.net/nih-should-b...
nickgeorge.net/nih-should-b...
Great piece from @jonathanwosen.bsky.social. antitrust law to fight the status quo in academic publishing www.statnews.com/2025/03/10/p...
Scientists’ suit against top academic publishers lays bare deep frustration over unpaid peer review
Researchers have sued six big academic publishers, arguing their practices are illegal and anticompetitive.
www.statnews.com
March 19, 2025 at 9:04 PM
Great piece from @jonathanwosen.bsky.social. antitrust law to fight the status quo in academic publishing www.statnews.com/2025/03/10/p...
Reposted by Nick George
"Scientists have been voting with their feet," Richard Sever said. Read more, from @mmolteni.bsky.social at @statnews.com
www.statnews.com/2025/03/11/l...
www.statnews.com/2025/03/11/l...
Life sciences preprint servers have grown up — and are setting out on their own
Richard Sever will be chief scientific and strategy officer of openRxiv, a nonprofit to ensure the future of biomedical preprint servers.
www.statnews.com
March 11, 2025 at 5:10 PM
"Scientists have been voting with their feet," Richard Sever said. Read more, from @mmolteni.bsky.social at @statnews.com
www.statnews.com/2025/03/11/l...
www.statnews.com/2025/03/11/l...
How do we ensure he doesn't weaponize "transparency" by selective publication and funding? Maybe push for preregistered, pre reviewed studies?
February 18, 2025 at 7:10 PM
How do we ensure he doesn't weaponize "transparency" by selective publication and funding? Maybe push for preregistered, pre reviewed studies?
The Woodrow Wilson bridge is quite a site when opened up! thanks for the tip @alxnow.bsky.social
January 15, 2025 at 3:52 AM
The Woodrow Wilson bridge is quite a site when opened up! thanks for the tip @alxnow.bsky.social