Natalie Wong
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natalie86md.bsky.social
Natalie Wong
@natalie86md.bsky.social
Medical Technology | Experienced Bioinformatician | Master of Bioinformatics | Love life and love yourself
Reposted by Natalie Wong
By investigating the peculiar states of the #amoeba Naegleria gruberi, researchers showed that #microtubules are more than just simple building blocks of the #cytoskeleton. In PNAS Journal Club: www.pnas.org/post/journal...

#tubulin #CellBiology #evolution
February 18, 2025 at 5:04 PM
Reposted by Natalie Wong
A new study in @cellpress.bsky.social Immunity from the lab of Dr. Benjamin Greenbaum provides insights into how #PancreaticCancer cells accommodate active retrotransposons without triggering the innate immune response. #oncsky #medsky
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
Overexpression of transposable elements is a common feature of cancer. Sun, You, et al. show that, in pancreatic ductal adenocarcinoma, tumor cells adapt through different mechanisms to mitigate a spe...
www.cell.com
November 27, 2024 at 6:57 PM
Reposted by Natalie Wong
Dr. Gabor Kovacs’ team at UHN's Krembil Brain Institute has characterized the diversity in the neuropathological changes responsible for #Alzheimers, including a novel subtype, paving the way for personalized care.

Read more ➡️ www.uhnresearch.ca/news/unlocki...
December 3, 2024 at 4:20 PM
Reposted by Natalie Wong
AI: The New Virtual Radiologist 🩻 🫁

Researchers at UHN’s Toronto General Hospital Research Institute are using AI to enhance the accuracy and consistency of organ evaluation for lung #transplantation.

Read more ➡️ www.uhnresearch.ca/news/ai-new-...
December 2, 2024 at 3:57 PM
Reposted by Natalie Wong
Blocking IRE1α enables RNA accumulation, triggering ZBP1-driven cell death and making cold TNBC tumors ICI-sensitive!

www.cell.com/cell/fulltex...
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer
Mechanisms dictating the form of chemotherapy-induced cancer cell death are elusive. This study reports that immunologically cold triple-negative breast cancer (TNBC) hijacks an ancient ER stress resp...
www.cell.com
November 26, 2024 at 5:50 PM
Reposted by Natalie Wong
A number of #AYA cancer survivors experience insurance and financial hardships, including foregoing medical care due to financial constraints, problems paying medical bills, and difficulties accessing loans or insurances. #survonc #ayacsm

link.springer.com/article/10.1...
Insurance, legal, and financial hardships of childhood and adolescent cancer survivors—a systematic review - Journal of Cancer Survivorship
Purpose Childhood and adolescent cancer survivors (CACS) experience medical and psychosocial adverse effects. Attention widens to include issues such as socio-bureaucratic hardships. This systematic r...
link.springer.com
November 29, 2024 at 4:46 PM
Reposted by Natalie Wong
🧪Participants who received a single dose had a 78% lower risk of symptomatic COVID-19 infection in the first month compared to placebo. That compares quite favorably with the efficacy of approved COVID vaccines, which has been reported to be 52% at four weeks.
apnews.com/press-releas...
apnews.com
November 26, 2024 at 2:00 PM
A must-have food for Thanksgiving 🦃🍴
November 29, 2024 at 12:58 AM
Share a little cutie. 🐶🐶
November 27, 2024 at 8:17 PM
Reposted by Natalie Wong
Vascular #GeneEditing therapy #MultisystemiSmoothMuscleDysfunctionSyndrome

ABE8e-eVRQR
AAV-PR
MYH11-Cre:ACTA2 R179H/+🐭
P3 iv▶️
8-wk editing
Liver 45%🫀12%🧠vessel 7% Aorta 1%

Lifespan 6➡️23 wk
⬇️Aorticφ
⬆️Locomotor
⬆️🧠Arteriolar SMC

@markelindsay.bsky.social bioRxiv 2024
www.biorxiv.org/content/10.1...
November 26, 2024 at 8:31 PM
Reposted by Natalie Wong
Hello! I'm Jane and I make nature inspired art using printmaking and mixed media processes including cyanotype, linocut and collage. I would describe myself as a left wing nature lover with plenty of woke thrown in! Would love to connect with like-minded folks on this platform 😊
November 23, 2024 at 4:01 PM
Single-cell RNA sequencing (scRNA-seq) is an important tool for analyzing the cellular composition and heterogeneity of organoids. Through scRNA-seq, researchers can accurately identify various cell types in neural organoids, including neural progenitor cells (NPCs), neurons, and glial cells.
November 26, 2024 at 5:56 AM
I am a new user of Bluesky. I look forward to meeting industry elites in the same industry through this platform and having more exchanges and learning with everyone. 🤝
November 26, 2024 at 5:18 AM