Miler Lee
mtleelab.bsky.social
Miler Lee
@mtleelab.bsky.social
Assoc Professor, Pitt BioSci. Eggs + gene regulation. Fish, frogs, cnidarians, ...
Reposted by Miler Lee
One thing we do in our review is just provide a source for references to many other reviews on individual topics, collect many refs for recent structural work, and also try to point to some older key papers. We also try to emphasize open questions or where interpretation can be tricky
I had started the notes for this thread awhile ago and am happy to put it out here. My student James Kuldell and I have a review: RNA Polymerase II activity control of gene expression and involvement in disease 3/
www.sciencedirect.com/science/arti...
RNA Polymerase II Activity Control of Gene Expression and Involvement in Disease
Gene expression is dependent on RNA Polymerase II (Pol II) activity in eukaryotes. In addition to determining the rate of RNA synthesis for all protei…
www.sciencedirect.com
November 27, 2024 at 6:58 PM
Reposted by Miler Lee
Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)
November 26, 2024 at 3:49 PM
Reposted by Miler Lee
Calling all systems and computational biologists in search of a faculty position:

We have Assistant and Associate Professor positions! 🚀

Pittsburgh is beautiful, and we are doing amazing science here.

cfopitt.taleo.net/careersectio...

cfopitt.taleo.net/careersectio...

Please apply by Dec 2!
Faculty.Professor.Assistant - Full-Time
Click the link provided to see the complete job description.
cfopitt.taleo.net
November 20, 2024 at 1:58 PM
Reposted by Miler Lee
PhD position(s) available in #development #genomics:  tinyurl.com/9dk9m29d
European (#MSCA) doctoral training network,  #DanioreCODE (tinyurl.com/2rz4mdsa).
How does  #transcription initiation regulation control #brain injury response and  #regeneration in #zebrafish?
November 18, 2024 at 1:42 PM
Congratulations to all who shared their science at #ABRCMS2024 , especially all of our amazing and accomplished Pitt students! So honored to get to work with all of you!
What an amazing time! Students at #ABRCMS2024 were so impressive! Incredibly proud of all the Pitt Biosci undergrads and grad students
November 18, 2024 at 2:32 AM
Reposted by Miler Lee
If you are going to #ABRCMS2024 in Pittsburgh stop by the NSF Bio Booth! We'll have tons of info for anyone interested in applying to NSF... that includes all you faculty in attendance! We're also doing an NSF101 professional development session today (11/13) from 5:15-6pm in CC401-402.
November 13, 2024 at 1:49 PM
Reposted by Miler Lee
New paper from the lab now published in MBE:
Evolutionary dynamics of pro-inflammatory caspases in primates and rodents! We found some cool stuff about how these immune proteins rapidly evolve, with implications for functional studies 1/n
academic.oup.com/mbe/advance-...
October 31, 2024 at 8:13 PM
Reposted by Miler Lee
Our new @CurrentBiology paper provides a rare glimpse into a morphological novelty in Drosophila eugracilis
In it, @gavinrrice and colleagues, infer and reproduce the likely initial steps of a novelty's formation
www.sciencedirect.com/science/arti...
October 28, 2024 at 7:20 PM