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msbioworks.bsky.social
MS Bioworks
@msbioworks.bsky.social
We productized proteomics services and tranformed the field. Here to discuss all things proteomics and occasionally stir the pot :)
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism

www.biorxiv.org/content/10.1...
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism
Mitochondria-lipid droplet (LD) interactions play a critical role in lipid metabolism and the progression of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). However, the dynamic ...
www.biorxiv.org
November 25, 2025 at 2:31 PM
For the initiated and uninitiated. Mani and Reni locking in.

www.youtube.com/watch?v=NSD1...
The Stone Roses - Fools Gold (Official Video)
YouTube video by StoneRosesVEVO
www.youtube.com
November 20, 2025 at 8:17 PM
The Astral Zoom paper is here: www.biorxiv.org/content/10.1...

Bravo to @jesperolsenlab.bsky.social for this notable comment:

"Notably, for both DIA-NN and Spectronaut,
inference to protein-coding genes was done via gene names, to avoid inflation of identification
rates via isoforms.
From HeLa to human blood: extending single-cell proteomics to the smallest immune cells
Single-cell proteomics (SCP) holds the promise of decoding cellular heterogeneity at the functional level, yet achieving deep and reproducible proteome coverage from individual cells has remained a fo...
www.biorxiv.org
November 13, 2025 at 11:07 PM
Reposted by MS Bioworks
The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database -- or you may be better off using TrEMBL.

www.matrixscience.com/blog/replace...

#proteomics #massspec
Replacements for NCBI nr
www.matrixscience.com
November 10, 2025 at 2:46 PM
Reposted by MS Bioworks
100 Python Projects — From Beginner to Expert
pythonclcoding.gumroad.com/l/100PythonP...
November 8, 2025 at 6:00 PM
Using @n8n.io a @Lego Buildhat for a @raspberrypi.com, an MCP server care of @anthropic.com and inspired by @jeffgeerling.com and @Networkchuck my son and I just made Agentic Lego!!! Tomorrow Art! MCP servers rule!
November 7, 2025 at 1:38 AM
Look, can we all agree that $1TN is insufficient for HRH Elon Musks pay packet? He deserves more than this, I wont rest until he gets $10TN. How's a guy gonna get by on $1TN?!?!
November 7, 2025 at 12:56 AM
Can anyone send me the link to the @pelosi.house.gov crowd funder? Poor gals gonna be broke after sticking it out in that government job for 20 years.
November 7, 2025 at 12:53 AM
The Agent wars have begun!

www.reuters.com/business/ret...
www.reuters.com
November 5, 2025 at 4:51 PM
Reposted by MS Bioworks
Our Institute Director, Professor Samra Turajlić, will be giving a public talk at @crick.ac.uk

💬Crick Crash Course: Immunotherapy
📅Wed 19th Nov
🕙10am
📌Crick Institute, London

For full details and to book: www.eventbrite.co.uk/e/crick-cras...

@turajliclab.bsky.social #Immunotherapy
November 4, 2025 at 11:54 AM
This is a pretty cool opportunity view.ceros.com/somalogic/25...
2025 SomaScan Grant Landing Page
view.ceros.com
November 3, 2025 at 4:12 PM
Reposted by MS Bioworks
How selective is your favourite electrophile? 🤔 🧪 🧫 🎯
Check out this thorough study from the @stephanhacker2.bsky.social lab, now published in Nature Chemistry!
Many congrats to everyone. We are thrilled to have contributed a little! Many congrats to @klanglab.bsky.social alumni Kristina and Marko!
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?

Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)

www.nature.com/articles/s41...
Profiling the proteome-wide selectivity of diverse electrophiles - Nature Chemistry
Covalent inhibitors are powerful entities in drug discovery. Now the amino acid selectivity and reactivity of a diverse electrophile library have been assessed proteome-wide using an unbiased workflow...
www.nature.com
October 30, 2025 at 2:39 PM
Attended a thought provoking presentation yesterday "The Future of AI for Society: Collaboration, upskilling and transforming together" given by @diyiyang.bsky.social Check out her labs work here: cs.stanford.edu/~diyiy/ and her teaching materials here: web.stanford.edu/class/cs329x/
Diyi Yang
cs.stanford.edu
October 30, 2025 at 1:37 PM
Reposted by MS Bioworks
Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.
a spongebob squarepants scene with a mailbox and a flower
ALT: a spongebob squarepants scene with a mailbox and a flower
media.tenor.com
October 28, 2025 at 4:39 PM
More good cross-linking #TeamMassSpec stuff on the horizon

www.asbmb.org/meetings-eve...
Advancing cross-linking mass spectrometry to elucidate cellular networks
Nov. 5, 2025 | 12:15 p.m. Eastern
www.asbmb.org
October 29, 2025 at 5:14 PM
While you were thinking AI is going to destroy us nobody noticed this happened....
October 29, 2025 at 1:07 AM
Reposted by MS Bioworks
Y'all. It's a HUGE day here on the ol' @wired.com because we have a giant package of stories on AI. Like deep, dark reporting on everything AI is doing to our world. I'll call out some favorite stories on subsequent posts, but for now—pick a card, any card

www.wired.com/ai-issue/
AI of a Thousand Faces
What happens now that AI is everywhere and in everything? WIRED can’t tell the future, but we can try to make sense of it. Behold: 17 readings from the furthest reaches of the AI age.
www.wired.com
October 27, 2025 at 7:06 PM
Any recommendations for an source sequence map generator? #Proteomics
October 27, 2025 at 6:47 PM
apnews.com/press-releas... and Anthropic Partner To Bring Scientific Illustrations to Claude For Life Sciences
BioRender and Anthropic Partner To Bring Scientific Illustrations to Claude For Life Sciences
TORONTO--(BUSINESS WIRE)--Oct 23, 2025-- BioRender, the world’s leading AI-powered platform for scientific communication, has announced a strategic partnership with Anthropic to integrate its extensiv...
apnews.com
October 24, 2025 at 6:41 PM
Reposted by MS Bioworks
Polyurethanes are made from 2 components – a polyol and a diisocyanate. Bio-based polyols are now commonplace, but now Algenesis has set up a pilot plant for its process to make bio-based diisocyanates, leading to fully bio-based and biodegradeable polyurethanes.
Algenesis cracks diisocyanate problem to make fully bio-based polyurethane
Process combines algal fermentation with flow chemistry and avoids hazardous phosgene
www.chemistryworld.com
October 23, 2025 at 9:10 AM
Plants that have given up on photosynthesis!

www.science.org/content/arti...
October 18, 2025 at 6:22 PM