Author | Lightnews

Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 6h

Even chimpanzees think rationally and weigh the evidence when making a choice ;-)
@science.org
www.science.org/doi/10.1126/...

Chimpanzees rationally revise their beliefs

The selective revision of beliefs in light of new evidence has been considered one of the hallmarks of human-level rationality. However, tests of this ability in other species are lacking. We examined...

www.science.org

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 3d

Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...

Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults | Annals of Internal Medicine

Background: Although physical activity recommendations increasingly consider daily step counts, it remains unclear whether step accumulation patterns—short versus sustained longer bouts—affect associa...

www.acpjournals.org

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 6d

Amazing video and description of Ectopia Cordis in the
@NEJM
! I have seen and written about this rare congenital heart and thoracic malformation. nejm.org/doi/full/10.... Pediatric Pathology> 1 I :85-95, 1991 & American Journal of Medical Genetics 44540 (1992)
#PediPath

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 6d

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions - Modern Pathology www.modernpathology.org/article/S089...

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions

Pediatric cutaneous T-cell lymphoproliferative disorders encompass a diagnostically complex set of rare diseases of undefined pathogenesis, including mycosis fungoides (MF), lymphomatoid papulosis (Ly...

www.modernpathology.org

Reposted by Miguel Reyes-Múgica, MD

Max Kozlov @maxkozlov.bsky.social · 8d

A vaccine that helps to fight cancer might already exist: People being treated for deadly cancers lived longer if they had received an mRNA COVID-19 vaccine.

The vaccines have this apparent life-extending effect not because they protect against COVID-19 but because they rev up the immune system.

People with some cancers live longer after a COVID vaccine

mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.

www.nature.com

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 9d

In a cohort of over 13,500 women with mean age ~72 years, >4,000 steps per day, at least 1-2 days per week, was associated with reduction in all-cause mortality and lower risk of cardiovascular disease
bjsm.bmj.com/content/earl...

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 10d

Peter Sellers was great!

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 11d

I have not used Spotify for years, since they contributed to misinformation. Bad platform.

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Reposted by Miguel Reyes-Múgica, MD

God @thegodpodcast.com · 11d

Spotify is running ICE ads. I went to cancel on mobile and saw that this isn’t allowed on mobile. They make you cancel on desktop. You think that’s gonna stop me, Spotify? I will erase you and forget you ever existed.

THOU SHALT CANCEL SPOTIFY!!!

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Reposted by Miguel Reyes-Múgica, MD

Dr Lindsey Fitzharris @drlindseyfitz.bsky.social · 13d

“Wound Man” is an illustration which first appeared in European surgical texts during the Middle Ages. It laid out schematically the various wounds a person might suffer in battle or in accidents, with accompanying text stating treatments.

It's Friday! Tag yourself as a wound 🫠

An illustration of a naked man. He is being hit or pierced with various weapons including knives, swords, and clubs. Next to the wounds is text describing accompany treatments. This illustration is from the Wellcome Collection in London.

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 13d

It is amazing to see the multitude of possibilities! The illustration may have represented an advanced medical compendium of traumatic medicine. We have made a few advances since then! #HistoryofMedicine is fascinating!

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 15d

A new world record for ultra rapid whole genome sequencing and interpretation for critically ill individuals less than 4hrs! www.nejm.org/doi/full/10....

Toward Same-Day Genome Sequencing in the Critical Care Setting | NEJM

Decisions about critical care are almost always made without access to genetic information. The authors report the application of a new method of DNA sequencing in infants in a neonatal intensive c...

www.nejm.org

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 21d

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 21d

Highly relevant paper for #PediPath: www.nature.com/articles/s41...

Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling - Scientific Reports

Scientific Reports - Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling

www.nature.com

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 21d

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions - Modern Pathology www.modernpathology.org/article/S089...

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions

Pediatric cutaneous T-cell lymphoproliferative disorders encompass a diagnostically complex set of rare diseases of undefined pathogenesis, including mycosis fungoides (MF), lymphomatoid papulosis (Ly...

www.modernpathology.org

1

Reposted by Miguel Reyes-Múgica, MD

NPR @npr.org · 21d

A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down. n.pr/3KIfcSn

This 4-year-old's heart is failing. A federal grant that might help him was canceled

A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down.

n.pr

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · 21d

#PediPath Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions - Modern Pathology www.modernpathology.org/article/S089...

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions

Pediatric cutaneous T-cell lymphoproliferative disorders encompass a diagnostically complex set of rare diseases of undefined pathogenesis, including mycosis fungoides (MF), lymphomatoid papulosis (Ly...

www.modernpathology.org

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Reposted by Miguel Reyes-Múgica, MD

LizdelaGarzaG @lizdelagarzag.bsky.social · 23d

Some arrive, others depart. John Gurdon, Nobel Laureate 2012, has passed.

www.cam.ac.uk/research/new...

Nobel Laureate Professor Sir John Gurdon dies aged 92

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.

www.cam.ac.uk

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 24d

"Anyone who is interested in the current and future states of healthspan treatments can appreciate......"—Prof @ctmurphy1.bsky.social @nature.com
www.nature.com/articles/d41...

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Reposted by Miguel Reyes-Múgica, MD

KOJAMF🤘🖤🤘 @kojamf.bsky.social · 25d

Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.

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Reposted by Miguel Reyes-Múgica, MD

Eric Topol @erictopol.bsky.social · 28d

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...

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Reposted by Miguel Reyes-Múgica, MD

LizdelaGarzaG @lizdelagarzag.bsky.social · Sep 30

September 29, 1964: the first Mafalda comic strip appears in Primera Plana magazine. The rest is history.

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Miguel Reyes-Múgica, MD @mreyesm.bsky.social · Sep 26

I hope you recover fully soon!

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Reposted by Miguel Reyes-Múgica, MD

Dr Lindsey Fitzharris @drlindseyfitz.bsky.social · Sep 25

This seems like a good time to repost this thread…. 💉

Dr Lindsey Fitzharris @drlindseyfitz.bsky.social · Feb 1

With science falling under increasing attack, this medical historian is here to remind people of the power of #vaccines. THREAD🧵

Hard-hitting polio advert from 1958. In the first half of the 20th century, polio was the leading cause of death in children and young adults. 1/7

An advertisement for the polio vaccine which reads: "they all got vaccine except dad...don't take a chance...take your polio shots!" It depicts a photo of a family gathered around a father who is in an iron lung.

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