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Reposted by Morandi Research Group

Michael Bogdos @mixalhsmpogdos.bsky.social · 22h

Great to see this published!

In short, we introduced causal inference logic to test which of metal electronics, ancillary ligand sterics and metal coordination number (CN) directly affect the rate of reductive elimination at Pd(II) (and presumably other metals...)

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Morandi Research Group @morandilab.bsky.social · 1d

Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Nathalie, Patrick, Fabio and Jan on this epic study of C-N red. elim. in @jacs.acspublications.org - using causal inference, organometallics, electrochemistry, kinetics and DFT. pubs.acs.org/doi/full/10....

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Morandi Research Group @morandilab.bsky.social · 1d

Congrats Bence on this @orgsynth.bsky.social prep describing a scalable nitrogen insertion protocol. Thanks to the Dixon lab for checking. 10.15227/orgsyn.102.0465

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Morandi Research Group @morandilab.bsky.social · 1d

Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow nitrogen atom insertion. @chemcomm.rsc.org @Innosuisse. pubs.rsc.org/en/content/a...

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Morandi Research Group @morandilab.bsky.social · 1d

Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Nathalie, Patrick, Fabio and Jan on this epic study of C-N red. elim. in @jacs.acspublications.org - using causal inference, organometallics, electrochemistry, kinetics and DFT. pubs.acs.org/doi/full/10....

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Morandi Research Group @morandilab.bsky.social · 1d

Congrats to Alberto and Patrick! @ethz.ch. youtu.be/NcMTOI25yb8?...

Recycling of organic pollutants: Nominated for the Spark Award

YouTube video by ETH News for Industry

youtu.be

Morandi Research Group @morandilab.bsky.social · Sep 2

Congrats to @fruepp.bsky.social, Vasily Grebennikov, Mykola Avramenko, Marc-Olivier Ebert "Kinetic, Spectroscopic, and Computational Investigation of Oxidative Aminative Alkene Cleavage Reveals an N-Iodonium-Iminoiodinane Pathway" now @chemrxiv.org - chemrxiv.org/engage/chemr...

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Morandi Research Group @morandilab.bsky.social · Sep 2

Congrats to Ann-Sophie Paschke, @ybraegger.bsky.social, Bence Botlik, Erich Staudinger, @origreen.bsky.social! "Carbon-to-nitrogen atom swap enables direct access to benzimidazoles from drug-like indoles". www.nature.com/articles/s41.... @natchem.nature.com.

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Reposted by Morandi Research Group

Nils Frank @nilsfrank99.bsky.social · Aug 21

Their electrochemical Lindane destruction has so much potential. Just thinking about the Lindane scandal in Basel-Kleinhüningen, where it was mixed into the street concrete…

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Reposted by Morandi Research Group

Synthesis Workshop @synthesisworkshop.bsky.social · Aug 9

Join us today to hear from Ann-Sophie Paschke and Stefanie Schiele from the @morandilab.bsky.social about their work on C-to-N atom swapping reactions!! Thanks to Karim for hosting and editing!

Link: youtu.be/D513hX1gOTg

@chemicalscience.rsc.org
doi.org/10.1039/D5SC...

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Morandi Research Group @morandilab.bsky.social · Aug 6

Congrats to Elliott, @hls111.bsky.social, Olivera, Patrick, Alexander and Daniel! Ligand Design Enables the Palladium-Catalyzed Intermolecular Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation @jacs.acspublications.org pubs.acs.org/doi/full/10....

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EUCOMC2025 @eucomc2025.bsky.social · Jul 10

Last day at #eucomc2025 starts with #plenary lecture @morandilab.bsky.social 🇨🇭 @ethz.ch introducing new concepts for atom and funcional transfer #Ni #organicsynthesis

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Morandi Research Group @morandilab.bsky.social · Jul 4

Congrats to Ann-Sophie Paschke, Eva Meeus, Florin and our collaborators from the pharmacy institute M. Masota and @nathalie-grob.bsky.social - Late-Stage Diversification of Peptides and Peptide Drugs through Nitrogen Atom Insertion | @ChemRxiv - go.shr.lc/44mL6Kg

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Morandi Research Group @morandilab.bsky.social · Jun 18

Congrats to Tanner Jankins, Barnabé Berger, Françoise A. Aouane, Sergio Barbeira-Arán, Christophe Didier, Bettina Hürlimann and Claudius Zimmer: C–H Functionalization via Single Atom Metathesis of C–H and C–X Bonds @jacs.acspublications.org pubs.acs.org/doi/10.1021/...

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Morandi Research Group @morandilab.bsky.social · Jun 18

Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow approach to nitrogen atom insertion. @Innosuisse. chemrxiv.org/engage/chemr...

Efficient Optimization and Synthesis of Diverse Azaarenes via Nitrogen Atom Insertion under Continuous Flow Conditions

We report the development of a continuous flow approach to nitrogen atom insertion. The setup is modular, enabling the rapid optimization of reaction conditions for a wide range of substrates. The mil...

chemrxiv.org

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Morandi Research Group @morandilab.bsky.social · Jun 18

Congrats to Ann-Sophie Paschke, Stefanie Schiele, Camille Pinard, and Filippo Sandrini: Chemodivergent C-to-N atom swap pubs.rsc.org/en/content/a.... Please also check our other paper (10.26434/chemrxiv-2024-prwm8) as well Studer's work.

Chemodivergent C-to-N atom swap from benzofurans to benzisoxazoles and benzoxazoles

Facile derivatization of biologically active compounds without prefunctionalization expands the chemical space and accelerates the discovery of new molecules. Atom swap reactions have recently emerged...

pubs.rsc.org

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Reposted by Morandi Research Group

Michelle Frei @michellefrei17.bsky.social · Apr 8

My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty

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Morandi Research Group @morandilab.bsky.social · Apr 11

Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Patrick, Nathalie, Fabio on this epic study of the factors governing reductive elimination - using causal inference, organometallics, electrochemistry, kinetics and DFT
@chemrxiv.bsky.social go.shr.lc/4j8O5MM

Metal Electronics Mediate Steric and Coordination Number Effects on Palladium (II) C–X Reductive Elimination

Reductive elimination is the key bond-forming elementary step in many transition metal catalyzed reactions relevant to the synthesis of pharmaceuticals, materials and fine chemicals. Metal electronics...

go.shr.lc

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Morandi Research Group @morandilab.bsky.social · Apr 8

Many congrats to Emilien Le Saux for this new publication in @jacs.acspublications.org describing a catalytic approach to Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds.
pubs.acs.org/doi/10.1021/...

Palladium-Catalyzed Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds

We report a new strategy for the catalytic iodination of nonactivated C(sp3)–H bonds. The method merges the concepts of shuttle and light-enabled palladium catalysis to employ aryl iodides as both hyd...

pubs.acs.org

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Waser Group @lcsolab.bsky.social · Mar 31

Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:

www.epfl.ch/labs/lcso/gr...

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Morandi Research Group @morandilab.bsky.social · Mar 7

Many Congrats to @ybraegger.bsky.social,
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...

Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds

The synthesis of nitrogen-containing molecules through carbon–nitrogen (C–N) bond formation is critical for the discovery and preparation of medicines, agrochemicals, and materials. Here, we report th...

www.science.org

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Reposted by Morandi Research Group

ESOC2025 @esoc2025.bsky.social · Mar 3

Are you inspired by complex reaction mechanisms and organometallic chemistry? At the European Symposium on Organic Chemistry (@ESOC_ISC) in Copenhagen (www.esoc2025.com) Jennifer A. Love (
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!

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Morandi Research Group @morandilab.bsky.social · Feb 20

Congrats to @sevenroediger.bsky.social and team as well as Tanner Jankins and team for having their papers highlighted this month in OPRD items of interest to process chem 😀 pubs.acs.org/doi/10.1021/...

Some Items of Interest to Process R&D Chemists and Engineers

pubs.acs.org

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Reposted by Morandi Research Group

Ali Coskun @coskunlab.bsky.social · Jan 31

It is time to say good bye to @pfritz.bsky.social. Aside from being a stellar PhD student, Patrick has contributed immensely to lab organization, You will be missed Patrick! At the same time, we are also very much excited for his new chapter in @morandilab.bsky.social . You will do great things!

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Morandi Research Group @morandilab.bsky.social · Jan 21

Thank you 😀

Waser Group @lcsolab.bsky.social · Jan 21

Welcome to @morandilab.bsky.social #Chemsky !

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