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Michelle Peckham @michellepeckham.bsky.social · 13h

A fantastic achievement

Glenn Carrington @drgcarrington.bsky.social · 13h

🚨 New paper alert! 🧬
Excited to share our latest preprint from the @michellepeckham.bsky.social lab 🎉

We reveal the structure of human non-muscle myosin 2A — showing how ionic interactions control auto-inhibition ⚡ and how disease mutations disrupt it 💪

👉 tinyurl.com/4fkxfv4e

#cryoEM #myosin

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Michelle Peckham @michellepeckham.bsky.social · 6d

#microscopy
#superresolution

Michelle Peckham @michellepeckham.bsky.social · 6d

Congratulations to Oli and the team for this lovely new paper on 'Clusternet': a new graph-based deep learning approach to analyse single molecule localisation data.
onlinelibrary.wiley.com/doi/epdf/10....

ClusterNet: Classifying Single‐Molecule Localization Microscopy Datasets with Graph‐Based Deep Learning of Supracluster Structure

You have to enable JavaScript in your browser's settings in order to use the eReader.

onlinelibrary.wiley.com

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Michelle Peckham @michellepeckham.bsky.social · 6d

Congratulations to Oli and the team for this lovely new paper on 'Clusternet': a new graph-based deep learning approach to analyse single molecule localisation data.
onlinelibrary.wiley.com/doi/epdf/10....

ClusterNet: Classifying Single‐Molecule Localization Microscopy Datasets with Graph‐Based Deep Learning of Supracluster Structure

You have to enable JavaScript in your browser's settings in order to use the eReader.

onlinelibrary.wiley.com

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Reposted by Michelle Peckham

Rita Strack @ritastrack.bsky.social · 7d

There is still plenty of time to apply! Feel free to reach out to me with questions, and please mention our ad to your colleagues or trainees!

Rita Strack @ritastrack.bsky.social · 22d

Nature Biomedical Engineering is hiring again! This time we're hoping to add an editor with machine learning expertise to the team (although we are open to those with other relevant expertise!) Deadline is Oct 20. Please RT! springernature.wd3.myworkdayjobs.com/SpringerNatu...

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Reposted by Michelle Peckham

jofmicroscopy.bsky.social @jofmicroscopy.bsky.social · 9d

The September 2025 special issue was edited by Clarissa Read, Ulm University, Germany, and Ulla Neumann, Max Planck Institute for Plant Breeding Research, Germany.

tinyurl.com/4j4pvyvz

Special Issue: Festschrift for Professor Paul Walther: Journal of Microscopy: Vol 299, No 3

The <em>Journal of Microscopy</em> is the oldest journal dedicated to the science of microscopy, publishing the latest advances in microscopy techniques and novel areas of application.

tinyurl.com

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Michelle Peckham @michellepeckham.bsky.social · 9d

A great set of articles!

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · 9d

New #collection of articles for Professor Jennifer Morgan's retirement from the Institute of Child Health in London.

Prof. Morgan was an MDEX consortium member, involved in Antisense Oligonucleotide clinical trials of DMD patients.

#myoblue #online-first

doi.org/10.1007/s109...

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Festschrift for Professor Jennifer Morgan - Journal of Muscle Research and Cell Motility

Journal of Muscle Research and Cell Motility -

doi.org

Reposted by Michelle Peckham

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Sep 5

New #review article by Monica Ridlon and co-authors:
Smooth muscle of the lower urinary tract- BK-RyR coupling in physiology and pathophysiology

#smooth-muscle #RyR #pathophysiology

doi.org/10.1007/s109...

This article forms part of the Smooth Muscle Cell Function in Health and Disease Collection

Smooth muscle of the lower urinary tract: BK-RyR coupling in physiology and pathophysiology - Journal of Muscle Research and Cell Motility

In the lower urinary tract, coordinated function between the bladder and urethra is essential for normal micturition, requiring smooth muscle contraction and relaxation in a tightly regulated cycle. D...

doi.org

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Reposted by Michelle Peckham

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Aug 21

New #review article by Santos et al.: Skeletal muscle alterations in Marfan syndrome: a systematic review

#onlinefirst #myoblue #marfan #syndrome #skeletal-muscle

doi.org/10.1007/s109...

Skeletal muscle alterations in Marfan syndrome: a systematic review - Journal of Muscle Research and Cell Motility

Marfan syndrome is an autosomal dominant multisystemic connective tissue disorder caused by mutations in the FBN1 gene. Although clinical changes in the cardiovascular, ocular, and skeletal systems ha...

doi.org

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Reposted by Michelle Peckham

Siân Culley @superresolusian.bsky.social · 17d

BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...

Bioimage Analysis Specialist | King's College London

www.kcl.ac.uk

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Reposted by Michelle Peckham

jofmicroscopy.bsky.social @jofmicroscopy.bsky.social · Sep 10

📣 Call for papers: "Taking the Stage: The Future of Microscopy"

The Journal has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers. The issue will be guest edited by Katherine Paine, Myfanwy Adams and Colum O'Leary.

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Reposted by Michelle Peckham

European Society of Cardiology @escardio.bsky.social · Aug 25

In 1952, the very first #ESCCongress was held, launching a journey that became the world’s biggest cardiology meeting. 💂 Can you guess where it all began? 👉 bit.ly/4fOM9YS

#ESC75Years #Cardiology

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Michelle Peckham @michellepeckham.bsky.social · Aug 21

A great video and a rising star - very proud of my daughter! Pls vote for her!!

Helena Aegerter @helligator.bsky.social · Aug 21

The New Scientist @newscientistnl.bsky.social has selected me for their Talent in Science competition: Vote for me here!
www.newscientist.nl/polls/new-sc...

If you need a little convincing, I made a little video explaining why researching mucus is so important
youtu.be/dYnXBnq4ttc

Learning about Charcot-Leyden crystals in mucus with Miles and Slime

YouTube video by Helena Aegerter

youtu.be

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Michelle Peckham @michellepeckham.bsky.social · Aug 21

What a fantastic achievement!

Helena Aegerter @helligator.bsky.social · Aug 21

The New Scientist @newscientistnl.bsky.social has selected me for their Talent in Science competition: Vote for me here!
www.newscientist.nl/polls/new-sc...

If you need a little convincing, I made a little video explaining why researching mucus is so important
youtu.be/dYnXBnq4ttc

Learning about Charcot-Leyden crystals in mucus with Miles and Slime

YouTube video by Helena Aegerter

youtu.be

Reposted by Michelle Peckham

jofmicroscopy.bsky.social @jofmicroscopy.bsky.social · Aug 20

📣 The Journal has published a special issue, honouring the career of Professor Paul Walther and his legacy in the field of electron microscopy.

In March 2024, after 46 years, he retired from Ulm University, Germany, where he led the Central Facility for Electron Microscopy.

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Reposted by Michelle Peckham

Fran Bottanelli @franbottanelli.bsky.social · Aug 13

Our protocol for gene editing is online and all plasmids are on @addgene.bsky.social! CRISPR away everybody and get in touch if you need anything 🤩

STAR Protocols @cp-starprotocols.bsky.social · Aug 7

Protocol for fast antibiotic resistance-based gene editing of mammalian cells with CRISPR-Cas9 #protocol #starprotocols #cellpress

Protocol for fast antibiotic resistance-based gene editing of mammalian cells with CRISPR-Cas9

Protein tagging with CRISPR-Cas9 enables the investigation of protein function in its native environment but is limited by low homology-directed repair (HDR) efficiency. Here, we present a protocol for fast antibiotic resistance-based gene editing with CRISPR-Cas9 (FAB-CRISPR), which streamlines N/C-terminal tagging using an antibiotic resistance cassette for rapid selection and enrichment of gene-edited cells. We describe in detail guide RNA and HDR donor plasmid cloning, transfection of editin...

dlvr.it

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Reposted by Michelle Peckham

Robert Insall @robinsall.bsky.social · Aug 10

Oh Lordy. It's true. GPT-5 really is that bad. This is quite spectacular.
PMs of the UK since the first world war. PhD level indeed. **shrug**

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Reposted by Michelle Peckham

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Jul 30

Update on our #journal #metrics

The Journal of Muscle Research and Cell Motility #JMRCM achieved >150k downloads in 2024

Submission to first decision (median): 2 days

5-year journal impact factor: 2.6

We invite #myoblue #scientists to publish with us

submission.nature.com/new-submissi....

Springer Nature account - log in or register

submission.nature.com

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Reposted by Michelle Peckham

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Jul 30

Original manuscript by Mari Matsumoto, Taku Hamada & Daiki Watanabe

Influence of neuromuscular transmission and Na+ channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles

doi.org/10.1007/s109...

#onlinefirst #myoblue #neuromuscular #transmission

Influence of neuromuscular transmission and Na+ channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles - Journal of Muscle Research and Cell Motility

Strength-duration (S-D) relationship reflects muscle excitability which partially determines force production. Isolated muscle contains part of nerve and neuromuscular junction, suggesting that muscle...

doi.org

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Michelle Peckham @michellepeckham.bsky.social · Jul 30

A great place to publish

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Jul 30

Update on our #journal #metrics

The Journal of Muscle Research and Cell Motility #JMRCM achieved >150k downloads in 2024

Submission to first decision (median): 2 days

5-year journal impact factor: 2.6

We invite #myoblue #scientists to publish with us

submission.nature.com/new-submissi....

Springer Nature account - log in or register

submission.nature.com

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Reposted by Michelle Peckham

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Jul 21

We have a few days left to #submit to our special collection on

Sarcomere mechanisms in health and disease

Submission deadline: August 1, 2025

link.springer.com/collections/...

Sarcomere mechanisms in health and disease

This Special Collection focuses on molecular to cell-level mechanisms that drive contractility in striated muscle. This area of research is transforming from ...

link.springer.com

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Michelle Peckham @michellepeckham.bsky.social · Jul 28

Do go see the RMS folk if you are there!

Sali Davis @becomingsali.bsky.social · Jul 27

@royalmicrosoc.bsky.social just landed the Microscopical Society of America's conference in Salt Lake. If you are here, come and pick up some great prize giveaways like some super Journal of Microscopy merchandise! @michellepeckham.bsky.social

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Reposted by Michelle Peckham

Lucien Hinderling @lhinderling.bsky.social · Jul 16

PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access): doi.org/10.1039/D5LC...

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Reposted by Michelle Peckham

Uri Manor @manorlaboratory.bsky.social · Jul 11

undark.org/2025/07/11/i...

Interview: How a Hearing-Loss Grant Got Cut in the Fight Over DEI

“It felt like the floor dropped out,” researcher Uri Manor said after the sudden suspension of his lab’s award.

undark.org

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Michelle Peckham @michellepeckham.bsky.social · Jul 4

A really interesting piece!

The Journal of Muscle Research and Cell Motility @jmrcm-springer.bsky.social · Jul 4

New #review by Terence Partridge: Skeletal muscle: a biologists’ adventure playground
"Scientists, like the generality of children, are compulsively drawn to the lure of mystery and conundrum, especially when associated with access to a variety of shiny toys."

doi.org/10.1007/s109...

#myoblue

Skeletal muscle: a biologists’ adventure playground - Journal of Muscle Research and Cell Motility

A brief discussion about skeletal muscle, aberrant expression of dystrophin from null mutations of the gene, potential explanations as to why this occurs, and how understanding this could be useful fo...

doi.org

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Michelle Peckham @michellepeckham.bsky.social · Jul 2

www.nature.com/articles/d41...

Trump team axes contracts with publishing giant Springer Nature

The action comes as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.

www.nature.com