Mathieu Desgroseilliers
@matdesgro.bsky.social
🇨🇦Critical Care pharmacist. PharmD MSc BCCCP Interested in all things #CriticalCare. Aiming to be the best version of myself.
FR/EN(at least trying)
#PharmSky #RxSky #ICUSky #EMSky
🛜 https://linktr.ee/matdesgro
FR/EN(at least trying)
#PharmSky #RxSky #ICUSky #EMSky
🛜 https://linktr.ee/matdesgro
Reposted by Mathieu Desgroseilliers
treatment of severe/refractory hypoglycemia (IBCC update)
commonly messed up in practice & literature 🤦♂️
key points:
🧃 IV dextrose gtts are good but not super effective
🧃 PO carbs are more effective
🧃 IV steroid for refractory dz
🧃 structured escalation
🧃 rarely needs ICU admit #EMIMCC
commonly messed up in practice & literature 🤦♂️
key points:
🧃 IV dextrose gtts are good but not super effective
🧃 PO carbs are more effective
🧃 IV steroid for refractory dz
🧃 structured escalation
🧃 rarely needs ICU admit #EMIMCC
November 30, 2025 at 5:18 PM
treatment of severe/refractory hypoglycemia (IBCC update)
commonly messed up in practice & literature 🤦♂️
key points:
🧃 IV dextrose gtts are good but not super effective
🧃 PO carbs are more effective
🧃 IV steroid for refractory dz
🧃 structured escalation
🧃 rarely needs ICU admit #EMIMCC
commonly messed up in practice & literature 🤦♂️
key points:
🧃 IV dextrose gtts are good but not super effective
🧃 PO carbs are more effective
🧃 IV steroid for refractory dz
🧃 structured escalation
🧃 rarely needs ICU admit #EMIMCC
Reposted by Mathieu Desgroseilliers
Something big is coming 🚀
Quelque chose arrive… Préparez-vous 🎙️
#paratus #paratuspodcast #readyforanything #emergencyresponse #launcingsoon
Quelque chose arrive… Préparez-vous 🎙️
#paratus #paratuspodcast #readyforanything #emergencyresponse #launcingsoon
November 30, 2025 at 6:21 PM
Something big is coming 🚀
Quelque chose arrive… Préparez-vous 🎙️
#paratus #paratuspodcast #readyforanything #emergencyresponse #launcingsoon
Quelque chose arrive… Préparez-vous 🎙️
#paratus #paratuspodcast #readyforanything #emergencyresponse #launcingsoon
Reposted by Mathieu Desgroseilliers
Crash course in hemodynamics:
November 29, 2025 at 9:45 PM
Crash course in hemodynamics:
Reposted by Mathieu Desgroseilliers
updated IBCC chapter on severe influenza
most notable updates are on the pharmacology of newer antivirals (peramavir & baloxavir)
oseltamavir remains 1st line for patients without contraindications
(yeap, data on these isn't great, but we're stuck with them)
emcrit.org/ibcc/influen... #EMIMCC
most notable updates are on the pharmacology of newer antivirals (peramavir & baloxavir)
oseltamavir remains 1st line for patients without contraindications
(yeap, data on these isn't great, but we're stuck with them)
emcrit.org/ibcc/influen... #EMIMCC
November 29, 2025 at 3:36 PM
updated IBCC chapter on severe influenza
most notable updates are on the pharmacology of newer antivirals (peramavir & baloxavir)
oseltamavir remains 1st line for patients without contraindications
(yeap, data on these isn't great, but we're stuck with them)
emcrit.org/ibcc/influen... #EMIMCC
most notable updates are on the pharmacology of newer antivirals (peramavir & baloxavir)
oseltamavir remains 1st line for patients without contraindications
(yeap, data on these isn't great, but we're stuck with them)
emcrit.org/ibcc/influen... #EMIMCC
Reposted by Mathieu Desgroseilliers
“The world is not magic — and that’s the most magical thing about it.”
— Sean Carroll
— Sean Carroll
November 29, 2025 at 1:04 AM
“The world is not magic — and that’s the most magical thing about it.”
— Sean Carroll
— Sean Carroll
Reposted by Mathieu Desgroseilliers
Today's Paper of the Day is:
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
November 29, 2025 at 1:20 PM
Today's Paper of the Day is:
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Update on Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Reposted by Mathieu Desgroseilliers
updated the acute liver failure chapter
biggest change is increasing support for early CRRT to remove NH3 (to reduce elevated intracranial pressure)
now rec'd for clinically overt encephalopathy (Grade 2-4)
if admitting to ICU for ALF & encephalopathy, just dialyze
emcrit.org/ibcc/alf/ #EMIMCC
biggest change is increasing support for early CRRT to remove NH3 (to reduce elevated intracranial pressure)
now rec'd for clinically overt encephalopathy (Grade 2-4)
if admitting to ICU for ALF & encephalopathy, just dialyze
emcrit.org/ibcc/alf/ #EMIMCC
November 28, 2025 at 1:51 PM
updated the acute liver failure chapter
biggest change is increasing support for early CRRT to remove NH3 (to reduce elevated intracranial pressure)
now rec'd for clinically overt encephalopathy (Grade 2-4)
if admitting to ICU for ALF & encephalopathy, just dialyze
emcrit.org/ibcc/alf/ #EMIMCC
biggest change is increasing support for early CRRT to remove NH3 (to reduce elevated intracranial pressure)
now rec'd for clinically overt encephalopathy (Grade 2-4)
if admitting to ICU for ALF & encephalopathy, just dialyze
emcrit.org/ibcc/alf/ #EMIMCC
Reposted by Mathieu Desgroseilliers
When I did my Med Ed masters, the course director's research interest was technology-assisted learning. He said he often asked supervisees whether tech was actually helpful.
Chap below just stepped down as Editor-In-Chief of the Journal of Computer-Assisted Learning.
bsky.app/profile/paul...
Chap below just stepped down as Editor-In-Chief of the Journal of Computer-Assisted Learning.
bsky.app/profile/paul...
“I read faster on screen” ≠ “I learn better on screen”
Study shows: more screen, less comprehension.
#edtech #assessment #EduSky
3starlearningexperiences.wordpress.com/2025/05/11/t...
Study shows: more screen, less comprehension.
#edtech #assessment #EduSky
3starlearningexperiences.wordpress.com/2025/05/11/t...
The Medium is NOT the Message
“I read faster on screen” ≠ “I learn better on screen” Study shows: more screen, less comprehension. #edtech #assessment
3starlearningexperiences.wordpress.com
November 29, 2025 at 12:07 PM
When I did my Med Ed masters, the course director's research interest was technology-assisted learning. He said he often asked supervisees whether tech was actually helpful.
Chap below just stepped down as Editor-In-Chief of the Journal of Computer-Assisted Learning.
bsky.app/profile/paul...
Chap below just stepped down as Editor-In-Chief of the Journal of Computer-Assisted Learning.
bsky.app/profile/paul...
Reposted by Mathieu Desgroseilliers
#PlasticWaste and #PlasticPollution - the #ClimateEmergency is worsening the #PublicHealth dangers
www.cnn.com/2025/11/27/c...
www.cnn.com/2025/11/27/c...
How extreme weather is making plastic pollution more mobile, more persistent and more hazardous | CNN
Microplastics are already an environmental and health threat, but as the world heats up, they are becoming a much bigger and more hazardous problem, according to a new analysis
www.cnn.com
November 29, 2025 at 9:11 AM
#PlasticWaste and #PlasticPollution - the #ClimateEmergency is worsening the #PublicHealth dangers
www.cnn.com/2025/11/27/c...
www.cnn.com/2025/11/27/c...
Reposted by Mathieu Desgroseilliers
Exercise improves child #ADHD, but this is the first trial to test it in adults:
▪ Large effect (0.9)
▪ Strength/aerobic 30-40 min/day
▪ Brief mindfulness component
pubmed.ncbi.nlm.nih.gov/41244864
Evidence: Moderate (6/10, high drop-outs, small, single-blind)
#mentalhealth #psychiatry #pmhnp
▪ Large effect (0.9)
▪ Strength/aerobic 30-40 min/day
▪ Brief mindfulness component
pubmed.ncbi.nlm.nih.gov/41244864
Evidence: Moderate (6/10, high drop-outs, small, single-blind)
#mentalhealth #psychiatry #pmhnp
November 28, 2025 at 1:02 PM
Exercise improves child #ADHD, but this is the first trial to test it in adults:
▪ Large effect (0.9)
▪ Strength/aerobic 30-40 min/day
▪ Brief mindfulness component
pubmed.ncbi.nlm.nih.gov/41244864
Evidence: Moderate (6/10, high drop-outs, small, single-blind)
#mentalhealth #psychiatry #pmhnp
▪ Large effect (0.9)
▪ Strength/aerobic 30-40 min/day
▪ Brief mindfulness component
pubmed.ncbi.nlm.nih.gov/41244864
Evidence: Moderate (6/10, high drop-outs, small, single-blind)
#mentalhealth #psychiatry #pmhnp
Reposted by Mathieu Desgroseilliers
Reposted by Mathieu Desgroseilliers
We are flooded with information yet starved of wisdom. Do you think the rise of AI will make things better, or worse?
November 28, 2025 at 1:22 PM
We are flooded with information yet starved of wisdom. Do you think the rise of AI will make things better, or worse?
Reposted by Mathieu Desgroseilliers
Reducing the chances of delirium in intensive care 🏥
A new @nihr.bsky.social trial will see if giving certain patients vitamin B1 can prevent and treat delirium.
It is led by @uhsft.bsky.social, @unisouthampton.bsky.social, @southamptonbrc.bsky.social and ICNARC
research.uhs.nhs.uk/news/vitamin...
A new @nihr.bsky.social trial will see if giving certain patients vitamin B1 can prevent and treat delirium.
It is led by @uhsft.bsky.social, @unisouthampton.bsky.social, @southamptonbrc.bsky.social and ICNARC
research.uhs.nhs.uk/news/vitamin...
November 27, 2025 at 12:34 PM
Reducing the chances of delirium in intensive care 🏥
A new @nihr.bsky.social trial will see if giving certain patients vitamin B1 can prevent and treat delirium.
It is led by @uhsft.bsky.social, @unisouthampton.bsky.social, @southamptonbrc.bsky.social and ICNARC
research.uhs.nhs.uk/news/vitamin...
A new @nihr.bsky.social trial will see if giving certain patients vitamin B1 can prevent and treat delirium.
It is led by @uhsft.bsky.social, @unisouthampton.bsky.social, @southamptonbrc.bsky.social and ICNARC
research.uhs.nhs.uk/news/vitamin...
Reposted by Mathieu Desgroseilliers
ESICM issues 2025 guidelines on circulatory shock, defining shock as acute circulatory failure with tissue hypoperfusion and offering 50 recommendations on clinical assessment, hemodynamic monitoring, fluid responsiveness and use of echocardiography. zurl.co/invjr
November 28, 2025 at 9:00 AM
ESICM issues 2025 guidelines on circulatory shock, defining shock as acute circulatory failure with tissue hypoperfusion and offering 50 recommendations on clinical assessment, hemodynamic monitoring, fluid responsiveness and use of echocardiography. zurl.co/invjr
Reposted by Mathieu Desgroseilliers
"Knowing a great deal is not the same as being smart; intelligence is not information alone but also judgement, the manner in which information is co-ordinated and used. Still, the amount of information to which we have accessed is one index of our intelligence."
-Carl Sagan, Cosmos
-Carl Sagan, Cosmos
November 21, 2025 at 1:42 PM
"Knowing a great deal is not the same as being smart; intelligence is not information alone but also judgement, the manner in which information is co-ordinated and used. Still, the amount of information to which we have accessed is one index of our intelligence."
-Carl Sagan, Cosmos
-Carl Sagan, Cosmos
Reposted by Mathieu Desgroseilliers
"We wish to pursue the truth no matter where it leads - but to find the truth, we need imagination and skepticism both. We will not be afraid to speculate, but we will be careful to distinguish speculation from fact."
— Carl Sagan
— Carl Sagan
November 22, 2025 at 1:31 AM
"We wish to pursue the truth no matter where it leads - but to find the truth, we need imagination and skepticism both. We will not be afraid to speculate, but we will be careful to distinguish speculation from fact."
— Carl Sagan
— Carl Sagan
Reposted by Mathieu Desgroseilliers
"But if intelligence is our only edge, we must learn to use it better, to sharpen it, to understand its limitations and deficiencies—to use it as cats use stealth, as walking sticks use camouflage, to make it the tool of our survival."
-Carl Sagan, Shadows of Forgotten Ancestors
-Carl Sagan, Shadows of Forgotten Ancestors
November 23, 2025 at 1:14 AM
"But if intelligence is our only edge, we must learn to use it better, to sharpen it, to understand its limitations and deficiencies—to use it as cats use stealth, as walking sticks use camouflage, to make it the tool of our survival."
-Carl Sagan, Shadows of Forgotten Ancestors
-Carl Sagan, Shadows of Forgotten Ancestors
Reposted by Mathieu Desgroseilliers
“Science, my lad, is made up of mistakes, but they are mistakes which it is useful to make, because they lead little by little to the truth.”
― Jules Verne, A Journey to the Center of the Earth
― Jules Verne, A Journey to the Center of the Earth
November 24, 2025 at 1:34 PM
“Science, my lad, is made up of mistakes, but they are mistakes which it is useful to make, because they lead little by little to the truth.”
― Jules Verne, A Journey to the Center of the Earth
― Jules Verne, A Journey to the Center of the Earth
Reposted by Mathieu Desgroseilliers
“We are all connected; To each other, biologically. To the earth, chemically. To the rest of the universe atomically.”
― Neil DeGrasse Tyson
― Neil DeGrasse Tyson
November 24, 2025 at 11:34 PM
“We are all connected; To each other, biologically. To the earth, chemically. To the rest of the universe atomically.”
― Neil DeGrasse Tyson
― Neil DeGrasse Tyson
Reposted by Mathieu Desgroseilliers
“The beauty of a living thing is not the atoms that go into it, but the way those atoms are put together.”
― Carl Sagan, Cosmos
― Carl Sagan, Cosmos
November 25, 2025 at 1:27 PM
“The beauty of a living thing is not the atoms that go into it, but the way those atoms are put together.”
― Carl Sagan, Cosmos
― Carl Sagan, Cosmos
Reposted by Mathieu Desgroseilliers
"We invented phonetic writing so we could put our sounds down on paper and, by glancing at a page, hear someone speaking in our head—an invention that became so widespread in the last few thousand years that we hardly ever stop to consider how astonishing it is."
-Carl Sagan, Billions & Billions
-Carl Sagan, Billions & Billions
November 26, 2025 at 1:30 PM
"We invented phonetic writing so we could put our sounds down on paper and, by glancing at a page, hear someone speaking in our head—an invention that became so widespread in the last few thousand years that we hardly ever stop to consider how astonishing it is."
-Carl Sagan, Billions & Billions
-Carl Sagan, Billions & Billions
Reposted by Mathieu Desgroseilliers
Patient with cirrhosis and INR of 3 needs a procedure
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
November 27, 2025 at 1:06 PM
Patient with cirrhosis and INR of 3 needs a procedure
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
Reposted by Mathieu Desgroseilliers
GLP-1's...GI safety better than we thought??
🤔🔼 risk of cholelithiasis by 2cases/1,000
🔼 risk of reflux by 4/1,000
😀No apparent increase in cholecystitis, cholangitis, pancreatitis, obstruction, ileus
There ain't no perfect drug, but this one has real benefits
#IMsky #Medsky #GIsky
🤔🔼 risk of cholelithiasis by 2cases/1,000
🔼 risk of reflux by 4/1,000
😀No apparent increase in cholecystitis, cholangitis, pancreatitis, obstruction, ileus
There ain't no perfect drug, but this one has real benefits
#IMsky #Medsky #GIsky
November 27, 2025 at 1:22 PM
Reposted by Mathieu Desgroseilliers
Vous venez ?
J'adore faire çà, à mon âge, avec 25 ans de recul de l'histoire de la réanimation des chocs. C'est tellement génial de voir par où nous sommes passés, les erreurs faites et comment (essayer de) faire mieux.
J'adore faire çà, à mon âge, avec 25 ans de recul de l'histoire de la réanimation des chocs. C'est tellement génial de voir par où nous sommes passés, les erreurs faites et comment (essayer de) faire mieux.
November 27, 2025 at 1:33 PM
Vous venez ?
J'adore faire çà, à mon âge, avec 25 ans de recul de l'histoire de la réanimation des chocs. C'est tellement génial de voir par où nous sommes passés, les erreurs faites et comment (essayer de) faire mieux.
J'adore faire çà, à mon âge, avec 25 ans de recul de l'histoire de la réanimation des chocs. C'est tellement génial de voir par où nous sommes passés, les erreurs faites et comment (essayer de) faire mieux.
Reposted by Mathieu Desgroseilliers
"Do not indoctrinate your children. Teach them how to think for themselves, how to evaluate evidence, and how to disagree with you.”
― Richard Dawkins, The God Delusion
― Richard Dawkins, The God Delusion
November 27, 2025 at 1:32 AM
"Do not indoctrinate your children. Teach them how to think for themselves, how to evaluate evidence, and how to disagree with you.”
― Richard Dawkins, The God Delusion
― Richard Dawkins, The God Delusion