MarkH
@markhoofnagle.medsky.social
Trauma Surgeon. Basic Scientist. UVA/UMD/UPenn. Now WashU/STL. Blocking is curating.
Pinned
MarkH
@markhoofnagle.medsky.social
· Nov 12
So I decided to contribute.
People here are skeptical thinkers from a variety of fields not just medicine - including law, journalism and academia.
Let me know who I missed. go.bsky.app/P8Vnf7M
People here are skeptical thinkers from a variety of fields not just medicine - including law, journalism and academia.
Let me know who I missed. go.bsky.app/P8Vnf7M
Yes. You should be hung out to dry for following illegal orders.
December 2, 2025 at 5:36 AM
Yes. You should be hung out to dry for following illegal orders.
Reposted by MarkH
also, annual reminder: fuck the foo fighters & especially dave grohl's bitch ass
I don't think I've ever talked on Bluesky about why I hate the Foo Fighters and Dave Grohl.
Don't read any further unless you're prepared for uncomfortable truths about the "Nicest Guy in Rock", and his very substantial body count & subsequent cover-up.
Don't read any further unless you're prepared for uncomfortable truths about the "Nicest Guy in Rock", and his very substantial body count & subsequent cover-up.
December 1, 2025 at 3:11 PM
also, annual reminder: fuck the foo fighters & especially dave grohl's bitch ass
I love this. Everyone who went along with this deserves this treatment - instant betrayal by the leopards eating faces who are now eating your face.
So you thought the criminals who ordered you to illegally kill have your back? Oh poor baby. Yall are screwed.
www.nytimes.com/2025/12/01/u...
So you thought the criminals who ordered you to illegally kill have your back? Oh poor baby. Yall are screwed.
www.nytimes.com/2025/12/01/u...
Hegseth Ordered a Lethal Attack but Not the Killing of Survivors, Officials Say
www.nytimes.com
December 2, 2025 at 4:53 AM
I love this. Everyone who went along with this deserves this treatment - instant betrayal by the leopards eating faces who are now eating your face.
So you thought the criminals who ordered you to illegally kill have your back? Oh poor baby. Yall are screwed.
www.nytimes.com/2025/12/01/u...
So you thought the criminals who ordered you to illegally kill have your back? Oh poor baby. Yall are screwed.
www.nytimes.com/2025/12/01/u...
Reposted by MarkH
Prasad's plan may be to make impossible stnds.
"It’s like being in a maze & there’s theoretically a way out, but it’s really a lie. It’s just all walls. Like everywhere you turn you hit a wall where they’re just trying to destabilize the vaccine effort." - D. Daskalakis, ex-director of CDC NCIRD.
"It’s like being in a maze & there’s theoretically a way out, but it’s really a lie. It’s just all walls. Like everywhere you turn you hit a wall where they’re just trying to destabilize the vaccine effort." - D. Daskalakis, ex-director of CDC NCIRD.
Prasad Email Suggests New US FDA Vaccine Standards Coming, But More Detail Wanted
Flu vaccines are specifically mentioned in the CBER director's internal email, but all new and some older vaccines seem to be affected. The impact on development programs is unclear.
insights.citeline.com
December 2, 2025 at 1:32 AM
Prasad's plan may be to make impossible stnds.
"It’s like being in a maze & there’s theoretically a way out, but it’s really a lie. It’s just all walls. Like everywhere you turn you hit a wall where they’re just trying to destabilize the vaccine effort." - D. Daskalakis, ex-director of CDC NCIRD.
"It’s like being in a maze & there’s theoretically a way out, but it’s really a lie. It’s just all walls. Like everywhere you turn you hit a wall where they’re just trying to destabilize the vaccine effort." - D. Daskalakis, ex-director of CDC NCIRD.
One of the most important biases to account for when studying humans, their behavior, and especially *performance improvement* is Goodhart’s law. When we make a metric a targetbit ceases to be valuable as a metric. Humans will always game systems for rewards and especially to keep their jobs.
Very interesting Gelman blog suggesting that a good amount of the "Mississippi Miracle" is selection bias (holding back lowest performers, who then don't take the 4th grade test) rather than improved learning
statmodeling.stat.columbia.edu/2025/12/01/h...
statmodeling.stat.columbia.edu/2025/12/01/h...
How much of “Mississippi’s education miracle” is an artifact of selection bias? | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
December 2, 2025 at 1:30 AM
One of the most important biases to account for when studying humans, their behavior, and especially *performance improvement* is Goodhart’s law. When we make a metric a targetbit ceases to be valuable as a metric. Humans will always game systems for rewards and especially to keep their jobs.
Reposted by MarkH
‘Remigration’ is a term that comes out of the European far right. Its use by the DHS account is a sign of democratic and epistemic collapse
November 28, 2025 at 8:59 PM
‘Remigration’ is a term that comes out of the European far right. Its use by the DHS account is a sign of democratic and epistemic collapse
Reposted by MarkH
He’s gotta be the most shameless yet skilled liar I have ever seen.
November 27, 2025 at 12:01 PM
He’s gotta be the most shameless yet skilled liar I have ever seen.
Reposted by MarkH
And COVID showed that MAHA and MAHA doctors have a very high tolerance for kids dying from vaccine preventable diseases.
This is pocket change to them.
They just don’t care.
This is pocket change to them.
They just don’t care.
Since this guy came on board, Louisiana has had a record pertussis year, with 2 infant deaths in the state. Now RFK Jr gave him a promotion up to the CDC.
CDC’s new top deputy had ordered his state health department to stop promoting mass vaccinations amid a flu surge www.washingtonpost.com/health/2025/...
November 27, 2025 at 5:26 PM
And COVID showed that MAHA and MAHA doctors have a very high tolerance for kids dying from vaccine preventable diseases.
This is pocket change to them.
They just don’t care.
This is pocket change to them.
They just don’t care.
Reposted by MarkH
The war will end when Russia stops fighting. Therefore, pressure has to be put on Russia, so that they stop believing that they will win. Why is that so hard to understand?
November 27, 2025 at 1:49 AM
The war will end when Russia stops fighting. Therefore, pressure has to be put on Russia, so that they stop believing that they will win. Why is that so hard to understand?
A reminder, he promised Robotaxi would be nationwide by the end of 2025.
But reality will never catch up with this grifter or his stock. electrek.co/2025/11/26/e...
But reality will never catch up with this grifter or his stock. electrek.co/2025/11/26/e...
Elon Musk slashes Tesla Robotaxi fleet goal from 500 to ~60 in Austin
Elon Musk announced last night that Tesla is planning to “roughly double” its Robotaxi fleet in Austin next month. While...
electrek.co
November 27, 2025 at 5:21 AM
A reminder, he promised Robotaxi would be nationwide by the end of 2025.
But reality will never catch up with this grifter or his stock. electrek.co/2025/11/26/e...
But reality will never catch up with this grifter or his stock. electrek.co/2025/11/26/e...
Jamelle is right. I’m in. gofund.me/ee2087c6e
November 27, 2025 at 3:19 AM
Jamelle is right. I’m in. gofund.me/ee2087c6e
Reposted by MarkH
I'm sorry, what?
November 27, 2025 at 12:47 AM
I'm sorry, what?
I was going to have Mexican tonight but I can not account for Santa Anna’s questionable embrace of dictatorial tactics and early support for the crown.
November 25, 2025 at 12:40 AM
I was going to have Mexican tonight but I can not account for Santa Anna’s questionable embrace of dictatorial tactics and early support for the crown.
Honestly they should shutter the Atlantic for this travesty. This tripe should haunt them for all time.
Over many interviews, Robert F. Kennedy Jr. told Michael Scherer about how he plans to remake America’s public-health system. Can he lead the scientific establishment he’s spent much of his life crusading against?
Read more in our new cover story: theatln.tc/q9hXxlbM
Read more in our new cover story: theatln.tc/q9hXxlbM
November 24, 2025 at 8:32 PM
Honestly they should shutter the Atlantic for this travesty. This tripe should haunt them for all time.
Wow. After a couple weeks with no political texts today I got 4!
I did a raft of f yous to all. Maybe it will buy me another few weeks of peace.
I did a raft of f yous to all. Maybe it will buy me another few weeks of peace.
November 24, 2025 at 2:20 AM
Wow. After a couple weeks with no political texts today I got 4!
I did a raft of f yous to all. Maybe it will buy me another few weeks of peace.
I did a raft of f yous to all. Maybe it will buy me another few weeks of peace.
Guess what NIH funded friends. No more paylines! This will be replaced by an entirely opaque system that appears to bool down to “whatever we want.”
They have destroyed the meritorious peer review system. Score will just be “considered”.
grants.nih.gov/news-events/...
They have destroyed the meritorious peer review system. Score will just be “considered”.
grants.nih.gov/news-events/...
Implementing a Unified NIH Funding Strategy to Guide Consistent and Clearer Award Decisions | Grants & Funding
grants.nih.gov
November 22, 2025 at 12:51 AM
Guess what NIH funded friends. No more paylines! This will be replaced by an entirely opaque system that appears to bool down to “whatever we want.”
They have destroyed the meritorious peer review system. Score will just be “considered”.
grants.nih.gov/news-events/...
They have destroyed the meritorious peer review system. Score will just be “considered”.
grants.nih.gov/news-events/...
Reposted by MarkH
Anyone know about LSU's Pennington Biomedical Research Center & why they'd be keen to appoint Malone? Hard to believe he didn't have insiders advocating for him.
Status they afforded him aside, Malone now has a formal institution to apply for research grants/contracts through. 🛟🧪
Status they afforded him aside, Malone now has a formal institution to apply for research grants/contracts through. 🛟🧪
November 19, 2025 at 12:27 AM
Anyone know about LSU's Pennington Biomedical Research Center & why they'd be keen to appoint Malone? Hard to believe he didn't have insiders advocating for him.
Status they afforded him aside, Malone now has a formal institution to apply for research grants/contracts through. 🛟🧪
Status they afforded him aside, Malone now has a formal institution to apply for research grants/contracts through. 🛟🧪
In a thread of worst sports photoshoots ever (recommend) I caught this one and thought “aww. Kinda cute.” Then the intrusive thoughts, “did he deflate the goat?”
November 19, 2025 at 12:43 AM
In a thread of worst sports photoshoots ever (recommend) I caught this one and thought “aww. Kinda cute.” Then the intrusive thoughts, “did he deflate the goat?”
Reposted by MarkH
Really ties all the threads together, this one
Andrew Johnson — a Jan. 6 rioter who went by "Am🇺🇸rican T🇺🇸rrorist” on Elon Musk’s platform — has been arrested on child molestation charges, with police saying he used the promise of a taxpayer-funded payout from Trump's DOJ to try and keep one of the victims silent.
theintercept.com/2025/11/17/p...
theintercept.com/2025/11/17/p...
Pardoned Capitol Rioter Tried to Hush Child Sex Victim With Promise of Jan. 6 Reparation Money, Police Say
Pardoned Capitol rioter Andrew Johnson tried to keep a child sex abuse victim quiet with claimed $10 million Jan. 6 reparations, police say.
theintercept.com
November 18, 2025 at 3:15 PM
Really ties all the threads together, this one
Reposted by MarkH
The legacy of these doctors and anyone who legitimized them along the way.
November 18, 2025 at 5:00 PM
The legacy of these doctors and anyone who legitimized them along the way.
Reposted by MarkH
NEW: ICE remains mum regarding prosecutor exposed as white supremacist.
"They want to signal to the other white supremacists...out there that under this administration things are going to be different and you’re not going to have to worry about losing your job"
www.texasobserver.org/ice-white-su...
"They want to signal to the other white supremacists...out there that under this administration things are going to be different and you’re not going to have to worry about losing your job"
www.texasobserver.org/ice-white-su...
ICE Still Won't Answer Questions About Prosecutor with White Supremacist X Account
Congressman Marc Veasey arrived at an ICE facility Monday in his latest attempt to follow up on the Observer's reporting.
www.texasobserver.org
October 20, 2025 at 6:23 PM
NEW: ICE remains mum regarding prosecutor exposed as white supremacist.
"They want to signal to the other white supremacists...out there that under this administration things are going to be different and you’re not going to have to worry about losing your job"
www.texasobserver.org/ice-white-su...
"They want to signal to the other white supremacists...out there that under this administration things are going to be different and you’re not going to have to worry about losing your job"
www.texasobserver.org/ice-white-su...
Reposted by MarkH
MUST WATCH: Meet the neo-Nazi targeting kids online, teaching them to hate and to prepare to kill www.newschannel5.com/news/newscha...
Meet the neo-Nazi targeting kids online, teaching them to hate and to prepare to kill
A Phil Williams NC5 Investigates report on a neo-Nazi targeting kids online, telling them to prepare for a 'race war'
www.newschannel5.com
November 18, 2025 at 12:26 AM
MUST WATCH: Meet the neo-Nazi targeting kids online, teaching them to hate and to prepare to kill www.newschannel5.com/news/newscha...
This was renewed for another season. This monologue notably is total bullshit from start to finish and typical of the style of the director where a common white guy explains how it really works to an educated woman (a PhD in this case IIRC). Billy Bob has turned shitheel.
Check out the @climatetown.bsky.social response to this episode if you haven’t. It’s good! youtu.be/wBC_bug5DIQ?...
How Oil Propaganda Sneaks Into TV Shows | Climate Town
YouTube video by Climate Town
youtu.be
November 17, 2025 at 9:23 PM
This was renewed for another season. This monologue notably is total bullshit from start to finish and typical of the style of the director where a common white guy explains how it really works to an educated woman (a PhD in this case IIRC). Billy Bob has turned shitheel.
He’s like Hitler in the bunker at this point moving around imaginary German units on a map while his generals give each other sidelong glances.
Trump on if he'll sign an Epstein files release bill: "We have nothing to do with Epstein. The Democrats do. All of his friends were Democrats. You look at this Reid Hoffman, Larry Summers, Clinton... all I want is I want for people to recognize the great job I've done on pricing, on affordability."
November 17, 2025 at 8:29 PM
He’s like Hitler in the bunker at this point moving around imaginary German units on a map while his generals give each other sidelong glances.
Techbros just invented Chucky.
“Marketed for kids 3-12, Kumma gave step-by-step instructions on a common “knot for beginners” who want to tie up their partner. Another time, the AI explored the idea of introducing spanking into a sexually-charged teacher-student dynamic, which is obviously ghoulishly inappropriate for young kids”
"Powered by OpenAI’s GPT-4o model by default...tests repeatedly showed that the AI toy dropped its guardrails the longer a conversation went on, until hitting rock bottom on incredibly disturbing topics."
November 17, 2025 at 7:26 AM
Techbros just invented Chucky.