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Jolene Sim @jolenesim.bsky.social · Sep 16

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Reposted by Jolene Sim

Sheila Macrine, PhD @macrinephd.bsky.social · Sep 5

New research calls an Alzheimer's protein "chameleon-like." 🦎 It shape-shifts to form toxic plaques, but this same flexibility also allows the plaques to break apart. onlinelibrary.wiley.com/doi/epdf/10.10…#Alzheimersr#amyloidi#researchc#neurosciencec#proteinfoldingn#dementiaia

https://onlinelibrary.wiley.com/doi/epdf/10.10…

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Eishi Noguchi @enog.bsky.social · Sep 5

While I am a Japanese, #Balkan #music used to be my favorite, and I still have a collection of cassette tapes with Balkan #FolkSongs 😉
These tapes are about 35 years old, but today, I felt like revisiting my old collection 😊
I have always loved those unique, irregular rhythms, like 11/16 😉

A few old cassette tapes that list names of various Balkan music.

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Reposted by Jolene Sim

Aut. Stuart Miller 📖✍️🤓 @authorstuartmiller.bsky.social · Mar 22

Fact: 1 suicide death every 11 minutes

Fact: Many adults think about suicide or attempt suicide. 13.2 million seriously thought about suicide

You have no idea how close someone might be to giving up on life b/c of #hate

No person should wake up fearing they'll be targeted by hate

End. All. Hate.

People are walking around every day hanging on by a thread. Be king or be quiet.

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Reposted by Jolene Sim

Katie Phang @katiephang.bsky.social · Mar 19

Something to think about

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Jolene Sim @jolenesim.bsky.social · Mar 23

WTAF?!

Erin Reed @erininthemorning.com · Mar 19

We reported on this a few days ago, but I want to point out this headline because this is where we are at.

A bill in Arkansas would ban gender affirming HAIRCUTS for transgender youth.

HAIRCUTS.

This is a straight up North Korea state sanctioned hairstyle proposed law for youth.

GOP bill could ban hairdressers from giving gender-nonconforming haircuts to minors - LGBTQ Nation

The bill would allow anyone to sue someone who affirms a young person's transition, and it specifically mentions hairstyles.

www.lgbtqnation.com

Jolene Sim @jolenesim.bsky.social · Mar 20

RIP to us all the next pandemic that hits us humans 😂 😂

Jolene Sim @jolenesim.bsky.social · Mar 20

www.nytimes.com/2025/03/18/h...

😂😂😂😂😂

RFK Jr.’s Prescription for Bird Flu on Farms: Let It Spread

The health secretary has suggested allowing the virus to spread, so as to identify birds that may be immune. Such an experiment would be disastrous, scientists say.

www.nytimes.com

Jolene Sim @jolenesim.bsky.social · Mar 20

www.nytimes.com/2025/03/18/h...

😂😂😂😂😂

RFK Jr.’s Prescription for Bird Flu on Farms: Let It Spread

The health secretary has suggested allowing the virus to spread, so as to identify birds that may be immune. Such an experiment would be disastrous, scientists say.

www.nytimes.com

Jolene Sim @jolenesim.bsky.social · Mar 6

So adorable! ❤️

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Jolene Sim @jolenesim.bsky.social · Mar 6

Thanks! Hopefully another year older another year wiser and all that good stuff

Grey and white tuxedo fluffy cat with long whiskers has his mouth wide open and teeth showing, eyes closed

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Jolene Sim @jolenesim.bsky.social · Mar 6

Thank you Berna! ❤️

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Jolene Sim @jolenesim.bsky.social · Feb 22

Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀 @mackayim.bsky.social · Feb 22

H/t @jonwensley.bsky.social over on Threads.
Best yet.

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Reposted by Jolene Sim

Tom Turkey [redacted] DO 🦃 @tom.medsky.social · Feb 21

Hearing about more dedicated public health professionals being let go and will re-iterate to any MD/DO with clinical interest in outpatient pediatrics HMU. We would be happy to have you.

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Jolene Sim @jolenesim.bsky.social · Feb 21

Finally got all my vaccines updated! Having all three at one go is no fun.

If you see this, it’s a reminder for you to get all yours done too!

Jolene Sim @jolenesim.bsky.social · Feb 17

“Depressive thoughts appeared from the origins of Humanity. They are found in philosophical writings and in literature since Antiquity.”

www.neuroscigroup.us/articles/ADA...

History of depression through the ages

Depressive thoughts appeared from the origins of Humanity. They are found in philosophical writings and in literature since Antiquity. They have been approached in a religious or medical way since alw...

www.neuroscigroup.us

Jolene Sim @jolenesim.bsky.social · Feb 17

Here is another interesting article from 2012 for additional reading:

www.nytimes.com/2012/04/22/m...

Post-Prozac Nation (Published 2012)

Just because the wonder drugs of the ’90s have disappointed doesn’t mean the science should be completely discarded. But it does mean we need a more sophisticated theory of depression.

www.nytimes.com

Jolene Sim @jolenesim.bsky.social · Feb 17

Quote from:

www.psychiatrypodcast.com/psychiatry-p....

The History, Mechanism, and Use of Antidepressants: Understanding Treatments for Depression — Psychiatry & Psychotherapy Podcast

Dr. David Puder and Dr. Michael Cummings explore antidepressants' history, mechanisms, and usage. Learn about the evolution from MAOIs to SSRIs, how these medications target neurotransmitter imbalance...

www.psychiatrypodcast.com

Jolene Sim @jolenesim.bsky.social · Feb 17

I quote, “Prior to the discovery of antipsychotics and antidepressants, depressed and anxious patients were sent to restful places, or asylums. In the late 19th century, the number of asylums surged.” 1/2

www.vanityfair.com/news/story/r...

RFK Jr. Goes After Widely Used Antidepressants, Claiming They Could Be A Threat To Americans

The newly confirmed US Secretary of Health and Human Services has falsely stated that SSRIs are more addictive than heroin and contribute to school shootings.

www.vanityfair.com

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Jolene Sim @jolenesim.bsky.social · Feb 17

some patients experiencing post-viral fatigue may have an underlying CoQ10 deficiency, which CoQ10 supplementation may restore.” 4/4

Jolene Sim @jolenesim.bsky.social · Feb 17

will protect the enzymes of the MRC from reactive oxygen species-induced impairment. Interestingly, several clinical studies have demonstrated an association between decreased endogenous CoQ10 levels and an increased susceptibility to COVID-19 infection, and, consequently, … 3/4

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Jolene Sim @jolenesim.bsky.social · Feb 17

… through its ability to restore electron flow in the mitochondrial respiratory chain (MRC), which will enhance ATP generation by oxidative phosphorylation. Furthermore, exogenous CoQ10 will also enhance mitochondrial antioxidant capacity, which… 2/4

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Jolene Sim @jolenesim.bsky.social · Feb 17

Interesting study, any thoughts?

www.mdpi.com/1422-0067/25...

“CoQ10 supplementation may ameliorate mitochondrial dysfunction and alleviate fatigue associated with Post Viral Fatigue Syndrome …” 1/4

Mitochondrial Dysfunction and Coenzyme Q10 Supplementation in Post-Viral Fatigue Syndrome: An Overview

Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune disorders of unknown causes characterised by disabling post-exertional fatigue, myalgia and joint pain, cognitive imp...

www.mdpi.com

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Jolene Sim @jolenesim.bsky.social · Feb 17

I have one that bit me after I told her there wasn’t any more bacon but she heard me crunch. 😂 should’ve seen her eyes when she heard the crunch!

Reposted by Jolene Sim

Gregg Gonsalves @gregggonsalves.bsky.social · Feb 17

The former NIH director speaks out. www.statnews.com/2025/02/16/n...

Trump administration layoffs set to hit NIH are ‘devastating,’ former director Monica Bertagnolli says

Sweeping layoffs are set to hit federal health and science agencies, including at the NIH, and former director Monica Bertagnolli called the situation at the NIH “devastating.”

www.statnews.com

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Beachbatcher 99 @beachbatcher.bsky.social · Feb 16

Your friendly neighborhood librarian here...buy physical copies of your favorite books, especially challenged or banned books. Preferably from small local merchants. That's all; carry on. #Read #BookSky #Resist 📚

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