JAMA Cardiology
@jamacardiology.com
JAMA Cardiology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
🌐 JAMACardiology.com
🌐 JAMACardiology.com
💬 Editorial: New analysis from the ASPREE trial suggests clonal hematopoiesis of indeterminate potential (CHIP) is linked to increased bleeding risk but not major cardiovascular events in healthy older adults.
ja.ma/4rUxRLP
ja.ma/4rUxRLP
December 14, 2025 at 1:00 PM
💬 Editorial: New analysis from the ASPREE trial suggests clonal hematopoiesis of indeterminate potential (CHIP) is linked to increased bleeding risk but not major cardiovascular events in healthy older adults.
ja.ma/4rUxRLP
ja.ma/4rUxRLP
In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically significant bleeding, and aspirin’s effects on CVD and bleeding did not differ based on CHIP presence. ja.ma/48M35fr
December 14, 2025 at 12:00 PM
In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically significant bleeding, and aspirin’s effects on CVD and bleeding did not differ based on CHIP presence. ja.ma/48M35fr
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/499NKGQ
December 13, 2025 at 4:00 PM
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/499NKGQ
RCT: Intracardiac echocardiography is non-inferior to transesophageal echocardiography for thromboembolic prevention in atrial fibrillation ablation, with added benefits in safety, efficiency, and patient comfort. ja.ma/4iV1Xe3
December 13, 2025 at 12:00 PM
RCT: Intracardiac echocardiography is non-inferior to transesophageal echocardiography for thromboembolic prevention in atrial fibrillation ablation, with added benefits in safety, efficiency, and patient comfort. ja.ma/4iV1Xe3
📢 This Special Communication describes the ZEUS trial, which will determine whether interleukin-6 inhibition with ziltivekimab reduces heart and kidney events in patients with atherosclerotic disease, chronic kidney disease, and systemic inflammation.
ja.ma/3MEZJDz
ja.ma/3MEZJDz
December 12, 2025 at 3:00 PM
📢 This Special Communication describes the ZEUS trial, which will determine whether interleukin-6 inhibition with ziltivekimab reduces heart and kidney events in patients with atherosclerotic disease, chronic kidney disease, and systemic inflammation.
ja.ma/3MEZJDz
ja.ma/3MEZJDz
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/48xaYXp
December 11, 2025 at 3:00 PM
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/48xaYXp
Integrating common, rare, and somatic genetic variants with clinical factors improves risk prediction for incident atrial fibrillation, aiding screening and prevention efforts. ja.ma/48MIA26
December 11, 2025 at 12:00 PM
Integrating common, rare, and somatic genetic variants with clinical factors improves risk prediction for incident atrial fibrillation, aiding screening and prevention efforts. ja.ma/48MIA26
🎧 Listen to Alfred E. Buxton, MD, and @MarieF_Poulin, MD, discuss their article "Mechanisms Underlying Alterations in Cardiac Conduction After Transcatheter Aortic Valve Replacement: Cardiac Conduction After TAVRt," with @rhythmkris, MD. ja.ma/4iK0rLI
December 10, 2025 at 5:30 PM
🎧 Listen to Alfred E. Buxton, MD, and @MarieF_Poulin, MD, discuss their article "Mechanisms Underlying Alterations in Cardiac Conduction After Transcatheter Aortic Valve Replacement: Cardiac Conduction After TAVRt," with @rhythmkris, MD. ja.ma/4iK0rLI
💬 Editors Note: Many post-TAVR conduction abnormalities resolve quickly and do not predict delayed heart block, suggesting routine permanent pacemaker implantation is often unnecessary.
ja.ma/4iK69xg
ja.ma/4iK69xg
December 10, 2025 at 5:00 PM
💬 Editors Note: Many post-TAVR conduction abnormalities resolve quickly and do not predict delayed heart block, suggesting routine permanent pacemaker implantation is often unnecessary.
ja.ma/4iK69xg
ja.ma/4iK69xg
Among 409 patients undergoing transcatheter aortic valve replacement, intraprocedural block occurred in the atrioventricular node or His bundle, with site-specific predictors for intraprocedural and delayed heart block.
ja.ma/3XLycmj
ja.ma/3XLycmj
December 10, 2025 at 4:30 PM
Among 409 patients undergoing transcatheter aortic valve replacement, intraprocedural block occurred in the atrioventricular node or His bundle, with site-specific predictors for intraprocedural and delayed heart block.
ja.ma/3XLycmj
ja.ma/3XLycmj
RCT: Among patients with obstructive prosthetic heart valve thrombosis, tenecteplase achieved higher complete thrombolytic success (97.5%) than alteplase (81.5%) and a shorter hospital stay. ja.ma/3XgMYBo
December 3, 2025 at 4:30 PM
RCT: Among patients with obstructive prosthetic heart valve thrombosis, tenecteplase achieved higher complete thrombolytic success (97.5%) than alteplase (81.5%) and a shorter hospital stay. ja.ma/3XgMYBo
In this secondary analysis of the AZALEA-TIMI 71 RCT, abelacimab consistently reduced the risk of bleeding relative to rivaroxaban irrespective of kidney function.
ja.ma/4pA6ViK
ja.ma/4pA6ViK
December 2, 2025 at 11:00 AM
In this secondary analysis of the AZALEA-TIMI 71 RCT, abelacimab consistently reduced the risk of bleeding relative to rivaroxaban irrespective of kidney function.
ja.ma/4pA6ViK
ja.ma/4pA6ViK
Editorial: The DANFLU-2 trial demonstrated that high-dose influenza vaccines have minor clinical advantages over standard-dose ones, highlighting the need for a health system focused on evidence rather than financial incentives.
ja.ma/4oiPphN
ja.ma/4oiPphN
December 1, 2025 at 12:00 PM
Editorial: The DANFLU-2 trial demonstrated that high-dose influenza vaccines have minor clinical advantages over standard-dose ones, highlighting the need for a health system focused on evidence rather than financial incentives.
ja.ma/4oiPphN
ja.ma/4oiPphN
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/48thQnp
Register for the webinar: ja.ma/48thQnp
November 28, 2025 at 6:36 PM
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/48thQnp
Register for the webinar: ja.ma/48thQnp
Among older adults, high-dose influenza vaccine modestly reduced cardiorespiratory and cardiovascular hospitalizations compared to standard-dose vaccine, finds this secondary analysis of the DANFLU-2 randomized clinical trial.
ja.ma/4agofVp
ja.ma/4agofVp
November 28, 2025 at 12:00 PM
Among older adults, high-dose influenza vaccine modestly reduced cardiorespiratory and cardiovascular hospitalizations compared to standard-dose vaccine, finds this secondary analysis of the DANFLU-2 randomized clinical trial.
ja.ma/4agofVp
ja.ma/4agofVp
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4onyiLV
November 27, 2025 at 12:00 PM
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4onyiLV
💬 Viewpoint: RCTs in tricuspid regurgitation indicate that transcatheter therapies can enhance quality of life and reduce certain clinical events compared to medical therapy.
ja.ma/49BoES7
ja.ma/49BoES7
November 26, 2025 at 5:30 PM
💬 Viewpoint: RCTs in tricuspid regurgitation indicate that transcatheter therapies can enhance quality of life and reduce certain clinical events compared to medical therapy.
ja.ma/49BoES7
ja.ma/49BoES7
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/3M3eDmX
Register for the webinar: ja.ma/3M3eDmX
November 26, 2025 at 5:00 PM
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/3M3eDmX
Register for the webinar: ja.ma/3M3eDmX
💬 Viewpoint: The TRILUMINATE Pivotal trial demonstrated quality-of-life improvement with transcatheter tricuspid repair, but effects on mortality and heart failure hospitalization were unclear or confounded by high crossover rates and open-label design.
ja.ma/3XlXeZ4
ja.ma/3XlXeZ4
November 26, 2025 at 5:00 PM
💬 Viewpoint: The TRILUMINATE Pivotal trial demonstrated quality-of-life improvement with transcatheter tricuspid repair, but effects on mortality and heart failure hospitalization were unclear or confounded by high crossover rates and open-label design.
ja.ma/3XlXeZ4
ja.ma/3XlXeZ4
Severe tricuspid regurgitation (TR) remains associated with poor prognosis and presents diagnostic and treatment challenges.
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
November 26, 2025 at 4:30 PM
Severe tricuspid regurgitation (TR) remains associated with poor prognosis and presents diagnostic and treatment challenges.
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
In the WHO African Region, older age, female sex, lower levels of education, and heavy alcohol consumption were linked to a decreased likelihood of achieving ideal or intermediate cardiovascular health. ja.ma/3LXmv9t
November 24, 2025 at 12:00 PM
In the WHO African Region, older age, female sex, lower levels of education, and heavy alcohol consumption were linked to a decreased likelihood of achieving ideal or intermediate cardiovascular health. ja.ma/3LXmv9t
Editorial: Microaxial flow pump therapy may be most beneficial for myocardial infarction patients with cardiogenic shock experiencing severe hypotension despite vasopressor use. ja.ma/487BtB1
November 21, 2025 at 1:00 PM
Editorial: Microaxial flow pump therapy may be most beneficial for myocardial infarction patients with cardiogenic shock experiencing severe hypotension despite vasopressor use. ja.ma/487BtB1
This post hoc analysis of the DanGer Shock RCT suggests that microaxial flow pump treatment may improve survival in patients with STEMI-related cardiogenic shock and profound systolic hypotension. ja.ma/4rdCDUn
November 21, 2025 at 12:00 PM
This post hoc analysis of the DanGer Shock RCT suggests that microaxial flow pump treatment may improve survival in patients with STEMI-related cardiogenic shock and profound systolic hypotension. ja.ma/4rdCDUn
Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. ja.ma/3KcEvfu
November 20, 2025 at 1:00 PM
Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. ja.ma/3KcEvfu
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. ja.ma/48mee7I
November 20, 2025 at 12:00 PM
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. ja.ma/48mee7I