JAMA Cardiology
@jamacardiology.com
JAMA Cardiology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
🌐 JAMACardiology.com
🌐 JAMACardiology.com
RCT: Among patients with obstructive prosthetic heart valve thrombosis, tenecteplase achieved higher complete thrombolytic success (97.5%) than alteplase (81.5%) and a shorter hospital stay. ja.ma/3XgMYBo
December 3, 2025 at 4:30 PM
RCT: Among patients with obstructive prosthetic heart valve thrombosis, tenecteplase achieved higher complete thrombolytic success (97.5%) than alteplase (81.5%) and a shorter hospital stay. ja.ma/3XgMYBo
In this secondary analysis of the AZALEA-TIMI 71 RCT, abelacimab consistently reduced the risk of bleeding relative to rivaroxaban irrespective of kidney function.
ja.ma/4pA6ViK
ja.ma/4pA6ViK
December 2, 2025 at 11:00 AM
In this secondary analysis of the AZALEA-TIMI 71 RCT, abelacimab consistently reduced the risk of bleeding relative to rivaroxaban irrespective of kidney function.
ja.ma/4pA6ViK
ja.ma/4pA6ViK
Editorial: The DANFLU-2 trial demonstrated that high-dose influenza vaccines have minor clinical advantages over standard-dose ones, highlighting the need for a health system focused on evidence rather than financial incentives.
ja.ma/4oiPphN
ja.ma/4oiPphN
December 1, 2025 at 12:00 PM
Editorial: The DANFLU-2 trial demonstrated that high-dose influenza vaccines have minor clinical advantages over standard-dose ones, highlighting the need for a health system focused on evidence rather than financial incentives.
ja.ma/4oiPphN
ja.ma/4oiPphN
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/48thQnp
Register for the webinar: ja.ma/48thQnp
November 28, 2025 at 6:36 PM
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/48thQnp
Register for the webinar: ja.ma/48thQnp
Among older adults, high-dose influenza vaccine modestly reduced cardiorespiratory and cardiovascular hospitalizations compared to standard-dose vaccine, finds this secondary analysis of the DANFLU-2 randomized clinical trial.
ja.ma/4agofVp
ja.ma/4agofVp
November 28, 2025 at 12:00 PM
Among older adults, high-dose influenza vaccine modestly reduced cardiorespiratory and cardiovascular hospitalizations compared to standard-dose vaccine, finds this secondary analysis of the DANFLU-2 randomized clinical trial.
ja.ma/4agofVp
ja.ma/4agofVp
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4onyiLV
November 27, 2025 at 12:00 PM
Among patients with severe symptomatic aortic stenosis at low to intermediate surgical risk, transcatheter aortic valve implantation was associated with a lower 1-year risk of all-cause death or any stroke. ja.ma/4onyiLV
💬 Viewpoint: RCTs in tricuspid regurgitation indicate that transcatheter therapies can enhance quality of life and reduce certain clinical events compared to medical therapy.
ja.ma/49BoES7
ja.ma/49BoES7
November 26, 2025 at 5:30 PM
💬 Viewpoint: RCTs in tricuspid regurgitation indicate that transcatheter therapies can enhance quality of life and reduce certain clinical events compared to medical therapy.
ja.ma/49BoES7
ja.ma/49BoES7
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/3M3eDmX
Register for the webinar: ja.ma/3M3eDmX
November 26, 2025 at 5:00 PM
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.
Register for the webinar: ja.ma/3M3eDmX
Register for the webinar: ja.ma/3M3eDmX
💬 Viewpoint: The TRILUMINATE Pivotal trial demonstrated quality-of-life improvement with transcatheter tricuspid repair, but effects on mortality and heart failure hospitalization were unclear or confounded by high crossover rates and open-label design.
ja.ma/3XlXeZ4
ja.ma/3XlXeZ4
November 26, 2025 at 5:00 PM
💬 Viewpoint: The TRILUMINATE Pivotal trial demonstrated quality-of-life improvement with transcatheter tricuspid repair, but effects on mortality and heart failure hospitalization were unclear or confounded by high crossover rates and open-label design.
ja.ma/3XlXeZ4
ja.ma/3XlXeZ4
Severe tricuspid regurgitation (TR) remains associated with poor prognosis and presents diagnostic and treatment challenges.
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
November 26, 2025 at 4:30 PM
Severe tricuspid regurgitation (TR) remains associated with poor prognosis and presents diagnostic and treatment challenges.
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
📌 This Review summarizes the anatomy, clinical manifestations, and diagnostic and management strategies of TR.
ja.ma/4pwQW4S
In the WHO African Region, older age, female sex, lower levels of education, and heavy alcohol consumption were linked to a decreased likelihood of achieving ideal or intermediate cardiovascular health. ja.ma/3LXmv9t
November 24, 2025 at 12:00 PM
In the WHO African Region, older age, female sex, lower levels of education, and heavy alcohol consumption were linked to a decreased likelihood of achieving ideal or intermediate cardiovascular health. ja.ma/3LXmv9t
Editorial: Microaxial flow pump therapy may be most beneficial for myocardial infarction patients with cardiogenic shock experiencing severe hypotension despite vasopressor use. ja.ma/487BtB1
November 21, 2025 at 1:00 PM
Editorial: Microaxial flow pump therapy may be most beneficial for myocardial infarction patients with cardiogenic shock experiencing severe hypotension despite vasopressor use. ja.ma/487BtB1
This post hoc analysis of the DanGer Shock RCT suggests that microaxial flow pump treatment may improve survival in patients with STEMI-related cardiogenic shock and profound systolic hypotension. ja.ma/4rdCDUn
November 21, 2025 at 12:00 PM
This post hoc analysis of the DanGer Shock RCT suggests that microaxial flow pump treatment may improve survival in patients with STEMI-related cardiogenic shock and profound systolic hypotension. ja.ma/4rdCDUn
Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. ja.ma/3KcEvfu
November 20, 2025 at 1:00 PM
Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. ja.ma/3KcEvfu
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. ja.ma/48mee7I
November 20, 2025 at 12:00 PM
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. ja.ma/48mee7I
Editor's Note: Herraiz-Adillo et al report that stage 2 hypertension and even modestly increased systolic blood pressure in young adulthood are independently associated with severe coronary stenosis in midlife. ja.ma/4pgDK3V
November 19, 2025 at 5:00 PM
Editor's Note: Herraiz-Adillo et al report that stage 2 hypertension and even modestly increased systolic blood pressure in young adulthood are independently associated with severe coronary stenosis in midlife. ja.ma/4pgDK3V
In this population-based cohort study, higher BP levels in adolescence were associated with a dose-dependent higher risk for atherosclerosis in middle age, particularly for severe coronary atherosclerosis. ja.ma/4oZ8cja
November 19, 2025 at 4:30 PM
In this population-based cohort study, higher BP levels in adolescence were associated with a dose-dependent higher risk for atherosclerosis in middle age, particularly for severe coronary atherosclerosis. ja.ma/4oZ8cja
In older patients with myocardial infarction and multivessel disease, physiology-guided complete revascularization achieved a sustained reduction in adverse outcomes compared to culprit-only treatment over a 3-year follow-up period. ja.ma/43yOORC
November 18, 2025 at 12:00 PM
In older patients with myocardial infarction and multivessel disease, physiology-guided complete revascularization achieved a sustained reduction in adverse outcomes compared to culprit-only treatment over a 3-year follow-up period. ja.ma/43yOORC
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing. ja.ma/485r8WB
November 17, 2025 at 12:00 PM
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing. ja.ma/485r8WB
A previously healthy 55-year-old man presented to his local family medicine clinic after waking up with a buzzing sensation in his chest. What would you do next?
ja.ma/46xum4h
ja.ma/46xum4h
November 15, 2025 at 12:00 PM
A previously healthy 55-year-old man presented to his local family medicine clinic after waking up with a buzzing sensation in his chest. What would you do next?
ja.ma/46xum4h
ja.ma/46xum4h
In a national US analysis of TAVR procedures from 2012 to 2024, annual volumes of redo TAVR and TAVR explant increased, TAVR reintervention beyond 5 years is predominantly performed via redo TAVR.
ja.ma/4gzabHE
ja.ma/4gzabHE
November 14, 2025 at 12:00 PM
In a national US analysis of TAVR procedures from 2012 to 2024, annual volumes of redo TAVR and TAVR explant increased, TAVR reintervention beyond 5 years is predominantly performed via redo TAVR.
ja.ma/4gzabHE
ja.ma/4gzabHE
An AI-ECG risk model demonstrated superior prediction of incident complete heart block within 1 year compared to traditional markers. ja.ma/4nSUb5p
November 13, 2025 at 2:00 PM
An AI-ECG risk model demonstrated superior prediction of incident complete heart block within 1 year compared to traditional markers. ja.ma/4nSUb5p
In a binational study of older adults with diabetes, nearly 60% in the US and 31% in Japan discontinued #GLP-1RAs within 12 months of starting injectable #semaglutide.
ja.ma/4mtbvxe
ja.ma/4mtbvxe
November 13, 2025 at 12:00 PM
In a binational study of older adults with diabetes, nearly 60% in the US and 31% in Japan discontinued #GLP-1RAs within 12 months of starting injectable #semaglutide.
ja.ma/4mtbvxe
ja.ma/4mtbvxe
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing.
ja.ma/4nI0QzJ
ja.ma/4nI0QzJ
November 12, 2025 at 5:30 PM
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing.
ja.ma/4nI0QzJ
ja.ma/4nI0QzJ
💬 Editorial: Guideline-directed medical therapy and structured plaque assessment may advance prevention for patients with nonobstructive, high-risk carotid plaques.
ja.ma/4qQJ4Nf
ja.ma/4qQJ4Nf
November 12, 2025 at 4:45 PM
💬 Editorial: Guideline-directed medical therapy and structured plaque assessment may advance prevention for patients with nonobstructive, high-risk carotid plaques.
ja.ma/4qQJ4Nf
ja.ma/4qQJ4Nf