Freya Harrison
@friendlymicrobe.bsky.social
Reader (Associate Professor) in Microbiology at the University of Warwick, UK.
Biofilm, chronic infection and ancientbiotics.
Biofilm, chronic infection and ancientbiotics.
Pinned
Harrison Lab @ University of Warwick, UK
We are a team of microbiologists working at the University of Warwick, UK.
www.youtube.com
The lab now has a YouTube channel to collate videos of the team talking science: www.youtube.com/@BreakingBio...
Congratulations to our poster prize winners at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms meeting 🎉 #MicroSky
November 28, 2025 at 1:05 PM
Congratulations to our poster prize winners at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms meeting 🎉 #MicroSky
Participate in the EUP OHAMR survey to strengthen AMR research capacity #AntibioticResistance #MicroSky ohamr.eu/2025/11/18/o...
Participate in the EUP OHAMR survey to strengthen AMR research capacity! - EUP OHAMR
We are launching a survey to identify gaps in strengthening research capacity in the field of AMR. Your input is valuable!
ohamr.eu
November 28, 2025 at 12:54 PM
Participate in the EUP OHAMR survey to strengthen AMR research capacity #AntibioticResistance #MicroSky ohamr.eu/2025/11/18/o...
Ending @bsacandjac.bsky.social #AntibioticResistance & Mechanisms with @astridpm.bsky.social talking about GARDP's work to advance antimicrobial R&D through their REVIVE programme. They have superb resources & webinars, linking academic/clinical/industry stakeholders revive.gardp.org #MicroSky
Home
Welcome to REVIVE!
For many years, antimicrobial researchers left the field or re-focused their activities risking losing invaluable experience and knowledge crucial for the discovery, research and de...
revive.gardp.org
November 28, 2025 at 12:38 PM
Ending @bsacandjac.bsky.social #AntibioticResistance & Mechanisms with @astridpm.bsky.social talking about GARDP's work to advance antimicrobial R&D through their REVIVE programme. They have superb resources & webinars, linking academic/clinical/industry stakeholders revive.gardp.org #MicroSky
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms:
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
November 28, 2025 at 12:22 PM
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms:
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
@reepkpd333.bsky.social is telling us how her hospital PK/PD lab is exploring suitable models to evaluate #phage + abx combinations scholar.google.com/citations?us... #MicroSky
More evolution at @bsacandjac.bsky.social #AntibioticResistance & mechanisms: @dralhubb.bsky.social exploring how order of antibiotic cycling affects selection, incl. for collateral resistance/susceptibility: order may affect specific mutations selected scholar.google.com/citations?us... #MicroSky
scholar.google.com
November 28, 2025 at 12:05 PM
More evolution at @bsacandjac.bsky.social #AntibioticResistance & mechanisms: @dralhubb.bsky.social exploring how order of antibiotic cycling affects selection, incl. for collateral resistance/susceptibility: order may affect specific mutations selected scholar.google.com/citations?us... #MicroSky
Evolution at @bsacandjac.bsky.social
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
Danna Gifford
School of Biological Sciences | Faculty of Biology Medicine and Health | University of Manchester
dannagifford.com
November 28, 2025 at 11:45 AM
Evolution at @bsacandjac.bsky.social
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
#AntibioticResistance & Mechanisms: @dannagifford.bsky.social found E. coli mutator genotypes don't just increase probability of resistance evolution, they increase probability of aa substitution vs. frameshift/indel - lower costs? dannagifford.com #MicroSky
Reposted by Freya Harrison
Who is missing our English Bluebells?
A bluebell a week until they wake again next year #14
A bluebell a week until they wake again next year #14
November 28, 2025 at 7:42 AM
Who is missing our English Bluebells?
A bluebell a week until they wake again next year #14
A bluebell a week until they wake again next year #14
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms, @cgmargarida.bsky.social is showing us how she uses zebrafish to find ways to induce trained immunity against respiratory pathogens - a high throughput model with key homology with humans warwick.ac.uk/fac/sci/life... #MicroSky
Dr Margarida Castro Gomes Spencer
warwick.ac.uk
November 28, 2025 at 10:03 AM
Now at @bsacandjac.bsky.social #AntibioticResistance & Mechanisms, @cgmargarida.bsky.social is showing us how she uses zebrafish to find ways to induce trained immunity against respiratory pathogens - a high throughput model with key homology with humans warwick.ac.uk/fac/sci/life... #MicroSky
90% of infections begin in the mucosa, but most vaccines are intravenous - so don't activate mucosal immunity. At @bsacandjac.bsky.social #AntibioticResistance & mechanisms, Ruth Griffin is showing her work developing mucosal vaccine delivery strategies www.nottingham.ac.uk/life-science... #MicroSky
People - The University of Nottingham
www.nottingham.ac.uk
November 28, 2025 at 9:44 AM
90% of infections begin in the mucosa, but most vaccines are intravenous - so don't activate mucosal immunity. At @bsacandjac.bsky.social #AntibioticResistance & mechanisms, Ruth Griffin is showing her work developing mucosal vaccine delivery strategies www.nottingham.ac.uk/life-science... #MicroSky
Something totally new to me at @bsacandjac.bsky.social
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity | EMBO Molecular Medicine
imageimageAttenuated Salmonella show promise as cancer therapeutics, yet T cells play no role
in efficacy, limiting combined checkpoint blockade therapies or induction of immune
memory. Improving T ce...
www.embopress.org
November 28, 2025 at 9:19 AM
Something totally new to me at @bsacandjac.bsky.social
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
#AntibioticResistance & mechanisms: Kendle Maslowski shows that attenuated Salmonella Typhimurium can infect tumours and kill cancer cells via metabolic competition www.embopress.org/doi/full/10.... #MicroSky
Reposted by Freya Harrison
Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech.
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
November 5, 2025 at 3:35 PM
Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech.
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Flash talk 4 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Caleb Marsh is designing dual efflux inhibitor-abx molecules, then testing them in @ukhsa.bsky.social's open innovation platform for abx development. Very promising drops in MIC & spontaneous resistance rates. #MicroSky
November 27, 2025 at 5:55 PM
Flash talk 4 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Caleb Marsh is designing dual efflux inhibitor-abx molecules, then testing them in @ukhsa.bsky.social's open innovation platform for abx development. Very promising drops in MIC & spontaneous resistance rates. #MicroSky
Flash talk 3 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @mwilde.bsky.social on AMR gene silencing via mutation & reversion: engineering in SNP in a carbapenemase alters AST profile, but effect depends on genetic background. #MicroSky
November 27, 2025 at 5:46 PM
Flash talk 3 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @mwilde.bsky.social on AMR gene silencing via mutation & reversion: engineering in SNP in a carbapenemase alters AST profile, but effect depends on genetic background. #MicroSky
Flash talk 2 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @taylorwr.bsky.social found that E. coli damaged but not killed by b-lactams die when they try to divide on abx-free solid medium, but not in liquid - so do plate count assays overestimate b-lactam killing? #MicroSky
November 27, 2025 at 5:31 PM
Flash talk 2 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! @taylorwr.bsky.social found that E. coli damaged but not killed by b-lactams die when they try to divide on abx-free solid medium, but not in liquid - so do plate count assays overestimate b-lactam killing? #MicroSky
Flash talk 1 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Ahmed Alomar selected E. coli for colistin resistance: clinical isolates evolved higher MIC than MG1655, associated with mutations in pmrA/B, many of those in pmrA not previously described. @imibirmingham.bsky.social #MicroSky
November 27, 2025 at 5:18 PM
Flash talk 1 @bsacandjac.bsky.social #AntibioticResistance & mechanisms! Ahmed Alomar selected E. coli for colistin resistance: clinical isolates evolved higher MIC than MG1655, associated with mutations in pmrA/B, many of those in pmrA not previously described. @imibirmingham.bsky.social #MicroSky
'Bacterial dietitian' @danybeste.bsky.social is telling @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop how switching C sources affects Tb antibiotic tolerance - can we use this info to design adjuvants that increase sensitivity? www.surrey.ac.uk/people/dany-... #MicroSky
Dr Dany Beste | University of Surrey
https://www.surrey.ac.uk/people/dany-beste#research#MicroSky
November 27, 2025 at 5:00 PM
'Bacterial dietitian' @danybeste.bsky.social is telling @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop how switching C sources affects Tb antibiotic tolerance - can we use this info to design adjuvants that increase sensitivity? www.surrey.ac.uk/people/dany-... #MicroSky
Synthetic teixobactin development: Ishwar Singh is telling @bsacandjac.bsky.social #antibioticResistance & mechanisms meeting about the long and winding road to promising new molecules with good bioactivity www.liverpool.ac.uk/people/ishwa... #MicroSky
Dr Ishwar Singh | Our people | University of Liverpool
www.liverpool.ac.uk
November 27, 2025 at 4:42 PM
Synthetic teixobactin development: Ishwar Singh is telling @bsacandjac.bsky.social #antibioticResistance & mechanisms meeting about the long and winding road to promising new molecules with good bioactivity www.liverpool.ac.uk/people/ishwa... #MicroSky
Now at @bsacandjac.bsky.social, @sykhalid.bsky.social explains that, while the outer leaflet of the Gram- OM is a calm sea anchored by OmpA to the cell wall, the phospholipids of the inner leaflet are paddling about madly beneath the surface. #MicroSky khalidlab.web.ox.ac.uk/publications
Publications
khalidlab.web.ox.ac.uk
November 27, 2025 at 4:20 PM
Now at @bsacandjac.bsky.social, @sykhalid.bsky.social explains that, while the outer leaflet of the Gram- OM is a calm sea anchored by OmpA to the cell wall, the phospholipids of the inner leaflet are paddling about madly beneath the surface. #MicroSky khalidlab.web.ox.ac.uk/publications
OMG no-one has every explained what "MD simulations" actually means before and I think @sykhalid.bsky.social has given me a sufficient understanding in about two minutes - amazing!
November 27, 2025 at 4:05 PM
OMG no-one has every explained what "MD simulations" actually means before and I think @sykhalid.bsky.social has given me a sufficient understanding in about two minutes - amazing!
I forgot a #MicroSky tag here!
Now at @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop, Kirsty Sands @ineosoxford.bsky.social stresses the dominance of Kleb pneumoniae in neonatal sepsis, and how the work she leads is quantifying the impact of AMR on neonatal sepsis in LMICs: www.ineosoxford.ox.ac.uk/barnards
BARNARDS
Causes and impacts of sepsis in new-born babies
www.ineosoxford.ox.ac.uk
November 27, 2025 at 3:18 PM
I forgot a #MicroSky tag here!
Now at @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop, Kirsty Sands @ineosoxford.bsky.social stresses the dominance of Kleb pneumoniae in neonatal sepsis, and how the work she leads is quantifying the impact of AMR on neonatal sepsis in LMICs: www.ineosoxford.ox.ac.uk/barnards
BARNARDS
Causes and impacts of sepsis in new-born babies
www.ineosoxford.ox.ac.uk
November 27, 2025 at 3:18 PM
Now at @bsacandjac.bsky.social #AntibioticResistance & mechanisms workshop, Kirsty Sands @ineosoxford.bsky.social stresses the dominance of Kleb pneumoniae in neonatal sepsis, and how the work she leads is quantifying the impact of AMR on neonatal sepsis in LMICs: www.ineosoxford.ox.ac.uk/barnards
Next at @bsacandjac.bsky.social #AntibioticResistance & mechanisms, @jodywinter.bsky.social is explaining how a partnership between academics, clinicians & health workers in Nottingham & Makerere is is sharing best practice in stewardship between UK & Uganda jodywinter.wixsite.com/waaw/cop #MicroSky
COP | Waaw
jodywinter.wixsite.com
November 27, 2025 at 2:36 PM
Next at @bsacandjac.bsky.social #AntibioticResistance & mechanisms, @jodywinter.bsky.social is explaining how a partnership between academics, clinicians & health workers in Nottingham & Makerere is is sharing best practice in stewardship between UK & Uganda jodywinter.wixsite.com/waaw/cop #MicroSky
What drives the acquisition and loss of #AntibioticResistance in Salmonella? @flashton.bsky.social kicking off the @bsacandjac.bsky.social resistance & mechanisms meeting, talking about pathogen genomic surveillance around the world, particularly in Africa www.psi.ox.ac.uk/our-team/phi... #MicroSky
Philip Ashton
Philip Ashton
www.psi.ox.ac.uk
November 27, 2025 at 2:02 PM
What drives the acquisition and loss of #AntibioticResistance in Salmonella? @flashton.bsky.social kicking off the @bsacandjac.bsky.social resistance & mechanisms meeting, talking about pathogen genomic surveillance around the world, particularly in Africa www.psi.ox.ac.uk/our-team/phi... #MicroSky
Congratulations @tosinorababa.bsky.social! #MicroSky
🎉 Congratulations to Oluwatosin Orababa @tosinorababa.bsky.social, one of the winners of our 2025 Infection Science Award! 🦠👏
Get to know them in our new interview: microb.io/3XFyCui
#InfectionScience #Microbiology #ResearchSpotlight
Get to know them in our new interview: microb.io/3XFyCui
#InfectionScience #Microbiology #ResearchSpotlight
November 25, 2025 at 12:31 PM
Congratulations @tosinorababa.bsky.social! #MicroSky
Reposted by Freya Harrison
Excited to have been selected as an Infection Science Awardee for 2025 by the Microbiology Society. Looking forward to presenting my research at this year’s Federation of Infection Science Conference in Bournemouth.
🎉 Congratulations to Oluwatosin Orababa @tosinorababa.bsky.social, one of the winners of our 2025 Infection Science Award! 🦠👏
Get to know them in our new interview: microb.io/3XFyCui
#InfectionScience #Microbiology #ResearchSpotlight
Get to know them in our new interview: microb.io/3XFyCui
#InfectionScience #Microbiology #ResearchSpotlight
November 25, 2025 at 12:07 PM
Excited to have been selected as an Infection Science Awardee for 2025 by the Microbiology Society. Looking forward to presenting my research at this year’s Federation of Infection Science Conference in Bournemouth.