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sevinc @ercanlab.bsky.social · 7d

The latest is from Porfirio and is recently published. Aside from the main points of the paper, I want to highlight this work for those who study enhancers in worms, as Porfirio characterized multiple through deletion and endogenous insertion of reporters.

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sevinc @ercanlab.bsky.social · 7d

C. elegans is a little animal with sexually dimorphic tails. Fitch lab does wonderful work on the evolution and transcriptional regulation of tail tip morphogenesis in nematodes.

Genetics Society of America @genetics-gsa.bsky.social · 8d

New in #GENETICS: Using Chip-seq and mutant analysis, Fernandez et al. show the transcriptional control of the male tail tip morphogenesis during development by the master regulator of a male-specific morphogenesis gene DMD-3. buff.ly/EGahYv2

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Genetics Society of America @genetics-gsa.bsky.social · 8d

New in #GENETICS: Using Chip-seq and mutant analysis, Fernandez et al. show the transcriptional control of the male tail tip morphogenesis during development by the master regulator of a male-specific morphogenesis gene DMD-3. buff.ly/EGahYv2

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Julien Richard Albert @jrichardalbert.bsky.social · 14d

I didn't think I could admire Azim Surani more than I already did
journals.biologists.com/dev/article/...

An interview with Azim Surani

Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...

journals.biologists.com

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Celja Uebel @celjauebel.bsky.social · 16d

Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :)
www.youtube.com/@Workingwith...

Working with C. elegans

This channel provides clear demonstrations of core C. elegans lab skills, including: recognizing life stages and common phenotypes, picking and manipulating worms, and maintaining healthy cultures. De...

www.youtube.com

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Robert Haase @haesleinhuepf.bsky.social · 16d

For academic purposes, I generated 100 UMAPs from the same tabular raw data, I sorted them and the result looks too funny to not share it with you 😃
haesleinhuepf.github.io/BioImageAnal...

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Matt Rockman @wormsrock.bsky.social · 23d

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

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sevinc @ercanlab.bsky.social · Aug 30

thanks for making a list, I d like to be added as well

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Jeremy Berg @jeremymberg.bsky.social · Jul 31

This is my reminder of what the American people need from her.

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Abby Dernburg @adernburg.bsky.social · Jul 31

For who still thinks this can’t happen here… it’s already happening.
www.theatlantic.com/science/arch...

Every Scientific Empire Comes to an End

America’s run as the premiere techno-superpower may be over.

www.theatlantic.com

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Mark A. Hanson @hansonmark.bsky.social · Jul 10

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?

That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience

A 🧵 1/n

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Ryan Grim @ryangrim.bsky.social · Jun 28

Andrew Cuomo thinks its absurd for the city try to to own a grocery story while New York State owns three (!) ski resorts and Cuomo personally oversaw their operation, even heralding it in his state of the state address.

Look it up if you don’t believe me.

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Bonnie Honig @bonniehonig.bsky.social · Jun 20

Great ad. This guy is great. Don’t let anyone tell you otherwise. Don’t be deterred by racist scare tactics! This guy is great, as is Lander.
Don’t rank Cuomo.

Zohran Kwame Mamdani @zohrankmamdani.bsky.social · Jun 20

If you’re under 30, you weren’t even born the last time Andrew Cuomo lived here.

This is your city. Vote like it.

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Paolo Crosetto @paolocrosetto.bsky.social · Jun 15

Springer-Nature launched a series of "Discover" journals that closely mimic MDPI titles -- sharing *identical* journal names, and likely similar business model.

What is going on, and why researcher will - as always - fall for it?

A 🧵

the-strain-on-scientific-publishing.github.io/website/post...

Springer Nature Discovers MDPI – The Strain on Scientific Publishing

Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro

the-strain-on-scientific-publishing.github.io

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Mark A. Hanson @hansonmark.bsky.social · Jun 10

New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊

Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).

Gross! 😀 1/n

#ResearchIntegrity #SciPub #AcademicSky

Spinger Nature Discovers MDPI – The Strain on Scientific Publishing

Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro

the-strain-on-scientific-publishing.github.io

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John Dennehy @drjdennehy.bsky.social · May 28

CUNY and SUNY faculty, please sign this letter to the NY State Congressional Delegation protesting cuts to research funding (and all the other crap going on)!

docs.google.com/forms/d/e/1F...

Thank you for reposting!

New York's Congressional Delegation Must Defend Federal Research Funding for CUNY & SUNY. List of signatories.

FACULTY & STAFF: ADD YOUR NAME BELOW TO THIS OPEN LETTER WRITTEN BY THE DEFENDING RESEARCH FUNDING WORKING GROUP OF THE PROFESSIONAL STAFF CONGRESS/CUNY Federal investment in scientific research gene...

docs.google.com

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Hell Gate *subscribe today!* @hellgatenyc.com · May 16

At last night's mayoral forum cosponsored by Hell Gate and NY Focus at the Public Theater, @zohrankmamdani.bsky.social asked @bradlander.bsky.social a question that Lander was more than ready to answer: What he thought was the worst thing Andrew Cuomo did as governor.

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Hank Green @hankgreen.bsky.social · May 17

The new Neil Halloran documentary on Smallpox has completely changed how I see the RFK Jr. version of the world. Neil (softly) argues that realizing that disease isn't the fault of the sick /or/ the fault of the Gods ushered in a new future where we felt the authority to care for each other.

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Hank Green @hankgreen.bsky.social · May 17

What a horror show to have put that man in charge of anything. The documentary is very short and very good. You can watch it here: www.youtube.com/watch?v=ybVZ...

Defeating a Virus That Killed Half a Billion People – The Plea

YouTube video by Neil Halloran

www.youtube.com

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Steve Smith @nightafternight.bsky.social · May 14

This was illuminating and useful… not at all surprised by my #1, but I made helpful discoveries elsewhere. (And no, I'm not telling.)

FW: Find your own match, powered by @thecity.nyc and @gothamist.com: projects.thecity.nyc/meet-your-ma...

Take the Quiz: Meet Your Mayor 2025

Candidates for NYC mayor told us where they stand on issues. Which is the top match for you? Find out before heading to the polls.

projects.thecity.nyc

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sevinc @ercanlab.bsky.social · May 7

our latest work summary: cohesin is preferentially loaded at/near active enhancers and loop extrudes in both directions, forming loops that create the dna contacts that appear as the newly defined "fountains" in hic maps pubmed.ncbi.nlm.nih.gov/40210441/

Cohesin organizes 3D DNA contacts surrounding active enhancers in C. elegans - PubMed

In mammals, cohesin and CTCF organize the 3D genome into topologically associating domains (TADs) to regulate communication between <i>cis</i>-regulatory elements. Many organisms, including <i>S. cere...

pubmed.ncbi.nlm.nih.gov

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NPR @npr.org · May 1

Politicians, lawyers and journalists who left behind autocratic systems in Europe, Asia and Latin America see the Trump administration employing similar methods.

People who fled authoritarian regimes say Trump's tactics remind them of home

Politicians, lawyers and journalists who left behind autocratic systems in Europe, Asia and Latin America see the Trump administration employing similar methods.

www.npr.org

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Javier Apfeld @javierapfeld.bsky.social · Apr 29

Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.

Email or DM me to find out more. Please share & repost!

Postdoctoral Research Associate, Biology

About the Opportunity Job Summary The Apfeld Lab at Northeastern University is seeking a postdoctoral researcher to investigate how genes work together to determine the maximum lifespan of the nematod...

northeastern.wd1.myworkdayjobs.com

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Whitney Gibbs @whitgibbs.bsky.social · Apr 30

My lab at NYU is hiring a postdoc interested in RNA biology and local translation in neurons following axonal injury/neurodegenerative diseases!! Apply here: apply.interfolio.com/165681

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Mark Peifer (He, him) @peiferlabunc.bsky.social · Mar 28

The DNA in our cells is not naked but instead is compacted by being wrapped around nucleosomes assembled from histone proteins. In our current view, this produces the chromatin architecture that leaves some regions open for transcription while others are more compacted & transcriptionally silent 1/n

Diagram of chromatin and nucleosomes
from https://www.genome.gov/genetics-glossary/Nucleosome

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