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Reposted by Michelle Luciano

Danielle @daniposthu.bsky.social · 16h

Proud that the third GWAS for Alzheimer's dementia from the PGC-ALZ working group was just posted online! Huge amounts of work, and what a great collaboration! Check out our exciting findings below 👇 @pgcgenetics.bsky.social #ctglab #alzheimer #dementia #GWAS

Emil Uffelmann @euffelmann.bsky.social · 23h

🚨 The preprint for our GWAS of Alzheimer’s disease (AD) is out

Preprint: medrxiv.org/content/10.1...

🧵

Genomic analyses reveal new insights into Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia, with global case numbers projected to reach 153 million in 2050. AD is highly heritable, with twin-based heritability estimates of 60-80%...

medrxiv.org

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Reposted by Michelle Luciano

NAPLIC @naplic.bsky.social · 1d

DLD is a lifelong condition and it does make lots of things more challenging. BUT once a person's needs are identified and they are supported they can thrive.
This is why we need far more awareness of Developmental Language Disorder (DLD)! www.naplic.org.uk/developmenta...
#DevLangDis #DLDday

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Reposted by Michelle Luciano

Julia M. Rohrer @dingdingpeng.the100.ci · 1d

New blog post!

Let's say you have two measures meant to capture the same confounder. They're highly correlated. Can you still proceed with your regression analysis?

(I admit, the title is a bit of a spoiler)

www.the100.ci/2025/10/13/i...

If you have two measures of the same confounder, you can just include both of them in your regression model

Sometimes, researchers worry about multicollinearity in situations where it’s actually a non-issue. Here’s one such scenario. Imagine a situation where you are interested in the effect of X on Y (X...

www.the100.ci

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Reposted by Michelle Luciano

Kathryn Paige Harden @kph3k.bsky.social · 1d

New from @ent3c.bsky.social in The Atlantic --

7 years (!) after Charles Murray made a bet with us that we'd "understand IQ genetically" by 2025, Eric describes how far we still are--and might always be--from that goal

www.theatlantic.com/science/2025...

Your Genes Are Simply Not Enough to Explain How Smart You Are

Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

www.theatlantic.com

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Reposted by Michelle Luciano

Ewan Birney @ewanbirney.bsky.social · 4d

I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Staff Scientist

About EMBL-EBI EMBL’s European Bioinformatics Institute is a data powerhouse, utilised on a global scale to advance scientific discovery through bioinformatics and solutions to some of the world’s mos...

embl.wd103.myworkdayjobs.com

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Reposted by Michelle Luciano

Michelle Lupton @michelleklupton.bsky.social · 5d

Our newest preprint is now available, using Mendelian randomisation to investigate the causal relationship between Frailty and Alzheimer's disease. www.medrxiv.org/content/10.1...
Awesome work from our visiting PhD student Jonny Flint #NGDgroup

Domains of Frailty as Early Risk Factors for Alzheimer Dementia - Genetic and Causal Evidence

Background Alzheimer’s dementia (AD) is a leading cause of disability and dependency in older adults. Frailty is a phenotypic risk factor for AD, but its causal role remains unclear - partly due to re...

www.medrxiv.org

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Reposted by Michelle Luciano

Uku Vainik @ukuvainik.bsky.social · 8d

Not to be missed!

Julia M. Rohrer @dingdingpeng.the100.ci · 8d

Happy to announce that I'll give a talk on how we can make rigorous causal inference more mainstream 📈

You can sign up for the Zoom link here: tinyurl.com/CIIG-JuliaRo...

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Reposted by Michelle Luciano

Rodrigo Braga @rodbraga.bsky.social · 7d

📣 New preprint from the Braga Lab! 📣

The ventral visual stream for reading converges on the transmodal language network

Congrats to Dr. Joe Salvo for this epic set of results

Big Q: What brain systems support the translation of writing to concepts and meaning?

Thread 🧵 ⬇️

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Michelle Luciano @drmluciano.bsky.social · 7d

A nice report on some of our recent dyslexia GWAS results. medicalxpress.com/news/2025-09...

Largest genetic study to date identifies 13 new DNA regions linked to dyslexia

Dyslexia is a neurodevelopmental condition estimated to affect between 5–10% of people living in most countries, irrespective of their educational and cultural background. Dyslexic individuals experie...

medicalxpress.com

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Michelle Luciano @drmluciano.bsky.social · 7d

Just back from holiday and pleased to see work led by a past Honours student, Diana Bicona, now published: rdcu.be/eH32N. We don't find any interaction between common genetic variant effects and broad measures of SES, but both main effects are signficant for reading achievement.

Dyslexia Polygenic Index and Socio-Economic Status Interaction Effects on Reading Skills in Australia and the United Kingdom

rdcu.be

Reposted by Michelle Luciano

Open Targets @opentargets.org · 26d

The Open Targets Platform autumn release is out! 🍂

We have ingested the full dataset of over 13 million enhancer-gene regulatory interactions in the human genome across 1,458 DNase-seq experiments covering 369 cell types and tissues from the ENCODE-rE2G model

blog.opentargets.org/open-targets...

Open Targets Platform 25.09 has been released!

The September 25 release includes enhancer-gene data predicted by ENCODE-rE2G, molQTL credible sets for targets, new options for the variant structural viewer, and a number of data updates from GWAS C...

blog.opentargets.org

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Reposted by Michelle Luciano

Barack Obama @barackobama.bsky.social · 26d

After years of complaining about cancel culture, the current administration has taken it to a new and dangerous level by routinely threatening regulatory action against media companies unless they muzzle or fire reporters and commentators it doesn’t like.

Let’s be clear about what happened to Jimmy Kimmel

Trump’s most brazen attack on free speech yet.

www.yahoo.com

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Michelle Luciano @drmluciano.bsky.social · 27d

Submissions are now open for the next European Conference on Personality (ECP22, Edinburgh, July 2026)! We welcome talks, posters and symposia. Also, keynote speakers and pre-conference workshops are now listed.
www.ecp22edinburgh.org/submission

Submission | Submit Your Work — ECP22

Prepare to submit symposia, papers, and posters for ECP22 Edinburgh 2026. Each delegate can present one paper or poster and be co-author on multiple submissions.

www.ecp22edinburgh.org

Reposted by Michelle Luciano

Carl T. Bergstrom @carlbergstrom.com · 29d

Oh man, thank you CNN.

It's been a heck of a day and I really needed the laugh.

CNN @cnn.com · 29d

Meta CEO Mark Zuckerberg has told analysts that people without smart glasses may one day be at a "significant cognitive disadvantage" compared to those who do use the tech: https://cnn.it/47L2Y5a

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Reposted by Michelle Luciano

Mike Inouye @mikeinouye.bsky.social · Aug 27

Sept is approaching & I can already hear initial chats/enquiries for potential PhD studies happening!

If you're interested in a PhD, check out our department @cam.ac.uk www.phpc.cam.ac.uk/education-an...

We've a super interdisciplinary faculty spanning primary care, data science, epidemiology etc

Doctoral Training | Department of Public Health and Primary Care (PHPC)

Course Code – MDPU22 A doctorate from the University of Cambridge is primarily a research degree based on a research programme developed in conjunction with a supervisor.

www.phpc.cam.ac.uk

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Michelle Luciano @drmluciano.bsky.social · 28d

I think it’s a bit unfair to blame the snails.

Michelle Luciano @drmluciano.bsky.social · 29d

Obscene.

Conrad Hackett @conradhackett.bsky.social · Sep 14

Only one country has more civilian guns than people.
www.smallarmssurvey.org/database/glo...

Chart showing number of civilian owned guns per 100 people in various countries. The US number - 120.5 - is much higher than any other country.

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Michelle Luciano @drmluciano.bsky.social · Sep 12

Paper led by Lucas Perry and using a multi-ancestry sample from the Born in Bradford cohort study.

One Health Genomics Edinburgh @onehealthgenomics.bsky.social · Sep 11

New Publication:

Polygenic Scores of Executive Function Provide Limited Support for Genetic Confounding With Socio-Economic Measures

@schoolofppls.bsky.social @drmluciano.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

Polygenic Scores of Executive Function Provide Limited Support for Genetic Confounding With Socio‐Economic Measures

While there is good reason to believe EF research has been subject to genetic confounding, the specialized samples required to test for it can be impractical for researchers. We tested one proposed a...

onlinelibrary.wiley.com

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Reposted by Michelle Luciano

Shai Carmi @shaicarmi.bsky.social · Sep 11

Brilliant paper by Visscher et al.

Populations differ in traits/disease burden. Are these differences due to genetics?

Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.

1/3

www.medrxiv.org/content/10.1...

Direct effect of genetic ancestry on complex traits in a Mexican population

Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...

www.medrxiv.org

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Michelle Luciano @drmluciano.bsky.social · Sep 11

I'm hardly surprised.

Michael Inzlicht @minzlicht.bsky.social · Sep 10

Major new paper by finds implicit measures like the IAT are no better than asking people directly about their biases. After decades of avoiding self-reports, turns out our sophisticated replacement tools work no better than what we abandoned. New post!

The Great Implicit Bias Bamboozle

Where were you when you first learned about implicit bias?

open.substack.com

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Michelle Luciano @drmluciano.bsky.social · Sep 10

my money is on the teenagers, bro 😄

Max Planck Institute for Psycholinguistics @mpi-nl.bsky.social · Sep 9

Children are not the main agents of language change. New paper by @limorraviv.bsky.social @damianblasi.bsky.social & @vkempe.bsky.social.
psycnet.apa.org/doi/10.1037/...
www.mpi.nl/publications...

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Michelle Luciano @drmluciano.bsky.social · Sep 10

Follow @clscohorts.bsky.social to keep up-to-date on this super important new birth cohort!

UK Research and Innovation @ukri.org · Sep 9

Announcing Generation New Era: the first UK-wide birth cohort study in 25 years.

It will study 30,000 children born in 2026 across the four nations of the UK.

Watch out for upcoming opportunities for researchers and other stakeholders to engage with the study team via @clscohorts.bsky.social

UKRI announces first UK-wide birth cohort study in 25 years

A ground-breaking UK-wide scientific study will help improve the lives of future generations by studying 30,000 children born in 2026.

www.ukri.org

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Reposted by Michelle Luciano

UCU Scotland @ucuscotland.bsky.social · Sep 9

#StopTheCuts UCU Edinburgh strikes highlighted in today’s Scotsman @ucuedinburgh.bsky.social #SaveHE ✊

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Reposted by Michelle Luciano

Abdel Abdellaoui @dr-appie.bsky.social · Sep 8

Some people call it a minefield. Others call it dangerous, even irresponsible. I call it the most promising field in life sciences.

My love letter to social science genetics: communities.springernature.com/posts/a-love...

A Love Letter to Social Science Genetics

Some people call social science genetics a minefield. Others call it dangerous, even irresponsible. I call it the most promising field in life sciences.

communities.springernature.com

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Michelle Luciano @drmluciano.bsky.social · Sep 4

and the music video was just perfect.

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