Sebastian Bruchmann
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doktorbasti.bsky.social
Sebastian Bruchmann
@doktorbasti.bsky.social
520 followers 350 following 12 posts
Assistant Research Professor @ University of Cambridge / HLRI Functional Genomics, AMR and Host Pathogen Interactions of Klebsiella pneumoniae and Pseudomonas aeruginosa https://sebbruchmann.github.io/
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Reposted by Sebastian Bruchmann
🚨 Another funded PhD alert🚨

We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀

If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬

➡️ tinyurl.com/3zvavp2t ⬅️

Apply by 6 Jan 2026 🗓️
The authors here present Dual Tn-seq, a method combining randomly barcoded transposon insertion sequencing (RB Tn-seq) with Cre-lox recombination, to generate and assay double mutants en masse.
The method looks great - congratulations to all involved!
Transposon insertion sequencing (Tn-seq / TraDIS) lets us identify essential genes and, in principle, study genetic interactions (epistasis). But in bacteria, doing this at scale is hard.
Fantastic paper: "Dual transposon sequencing profiles the genetic interaction landscape in bacteria" out now in Science www.science.org/doi/10.1126/...
Reposted by Sebastian Bruchmann
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
Reposted by Sebastian Bruchmann
OK, here it is. Come work with me at the University of Liverpool making ALL THE AI models from ALL THE prokaryote pangenome data. Heck, we will make models from ALL the pangenomes, even eukaryotes!!! (link below👇) 1/4
Reposted by Sebastian Bruchmann
Reposted by Sebastian Bruchmann
Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU.

my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
I haven't done this in E. coli, but in Pseudomonas the attTn7 site via mini-Tn7 transposon integration worked well.
Had a brilliant time in Liverpool at Edge Hill University for the Galleria mellonella Workshop 🐛
Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
Reposted by Sebastian Bruchmann
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
Wow - that is amazing! Many, many congratulations 👏🥳
Many, many congratulations Caity - so excited for you 🎉🥳
Many congratulations! 🎉
I've been using them for a while now and still can't believe how bright they are. Fantastic work! 👏
Reposted by Sebastian Bruchmann
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
Reposted by Sebastian Bruchmann
Reposted by Sebastian Bruchmann
Free #bioinformatics toolkit for #biologists!

Master #Linux, basic scripting, and advanced Nextflow pipelines, with our #OnlineCourses that guide you through complete bioinformatics workflows.

Gain deeper insights from your biological research🚀

📎 Info: bit.ly/4aMV22B
Reposted by Sebastian Bruchmann
Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe!
www.cmfi.uni-tuebingen.de/mariecuriephd
endamr.eu
Reposted by Sebastian Bruchmann
We’ve just released a public Pathogenwatch collection of the MRSN Diversity Panel comprising 100 diverse K. pneumoniae clinical isolates: pathogen.watch/collection/8... #KlebClub
Pathogenwatch
A global platform for genomic surveillance.
pathogen.watch
Reposted by Sebastian Bruchmann
🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution @mermanchester.bsky.social Join us! #microsky
www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Experimental Evolution:Manchester
www.jobs.manchester.ac.uk
Reposted by Sebastian Bruchmann
Sie suchen #Infektionsforscherinnen? Wir haben ein #StarterPack mit allen Infect-Net-Wissenschaftlerinnen auf BlueSky zusammengestellt:
🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋
👉 go.bsky.app/JU8KaeQ
Great collection of papers on adaptive evolution of AMR
Writing lecture slides on 'evolution of AMR' - what are your favourite experimental evolution papers?

Bonus points if not E. coli. #microsky
Reposted by Sebastian Bruchmann
Don't know who to follow for the best in microbial bioinformatics?

This is the Starter Pack you need!

bsky.app/starter-pack...