Congrats to @camolsan.bsky.social @aliciaperezlorente.bsky.social and colleges for this fantastic work.
Happy to share our paper from a new research line led by @camolsan.bsky.social, where we engineered the T6SS of Pseudomonas putida to deliver effectors against bacterial competitors and fungal pathogens like Botrytis cinerea. @ihsmumacsic.bsky.social
jbioleng.biomedcentral.com/articles/10....
jbioleng.biomedcentral.com/articles/10....
Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors - Journal of Biological Engineering
Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine...
jbioleng.biomedcentral.com
April 3, 2025 at 6:45 PM
Congrats to @camolsan.bsky.social @aliciaperezlorente.bsky.social and colleges for this fantastic work.
Reposted
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
A nucleosome switch primes hepatitis B virus infection
A reconstituted cccDNA platform facilitated the discovery of an early chromatinization
event that promotes transcription of the hepatitis B virus (HBV) regulatory X gene.
The use of a small-molecule c...
www.cell.com
February 21, 2025 at 5:31 PM
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
Reposted
Excited to share our latest collaboration with UNIBO, @ihsmumacsic.bsky.social, and ICMS 🌿 on developing a sustainable cling film for food packaging 🍃. A step forward toward greener materials and a more eco-friendly future! 🌍✨
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Triphenyl Acetic Glyceroate as a sustainable multifunctional additive for developing transparent, biodegradable, and flexible polylactide green alternative to polyethylene-based films for food packagi...
Polylactide-based materials represent a promising bio-based alternative to traditional food packaging polymers. However, their widespread use is still…
www.sciencedirect.com
February 21, 2025 at 6:27 PM
Excited to share our latest collaboration with UNIBO, @ihsmumacsic.bsky.social, and ICMS 🌿 on developing a sustainable cling film for food packaging 🍃. A step forward toward greener materials and a more eco-friendly future! 🌍✨
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted
The spread of agriculture didn’t just change our diets—it altered our jaws as well, making it easy to pronounce "f"s and "v"s and opening a whole new world of words.
Learn more on #WorldAnthropologyDay: https://scim.ag/4gLysc0
Learn more on #WorldAnthropologyDay: https://scim.ag/4gLysc0
February 20, 2025 at 3:10 PM
The spread of agriculture didn’t just change our diets—it altered our jaws as well, making it easy to pronounce "f"s and "v"s and opening a whole new world of words.
Learn more on #WorldAnthropologyDay: https://scim.ag/4gLysc0
Learn more on #WorldAnthropologyDay: https://scim.ag/4gLysc0
Reposted
Researchers have developed a deep learning protein language model, ESM3, that enables programmable protein design.
Learn more in this week's issue of Science: https://scim.ag/3Qo3HPw
Learn more in this week's issue of Science: https://scim.ag/3Qo3HPw
February 20, 2025 at 7:06 PM
Researchers have developed a deep learning protein language model, ESM3, that enables programmable protein design.
Learn more in this week's issue of Science: https://scim.ag/3Qo3HPw
Learn more in this week's issue of Science: https://scim.ag/3Qo3HPw
Reposted
Reposted
A novel regulation on the developmental checkpoint protein Sda that controls sporulation and biofilm formation in Bacillus subtilis
#JBacteriol from Yunrong Chai
journals.asm.org/doi/10.1128/...
#JBacteriol from Yunrong Chai
journals.asm.org/doi/10.1128/...
A novel regulation on the developmental checkpoint protein Sda that controls sporulation and biofilm formation in Bacillus subtilis | Journal of Bacteriology
Genome-wide ribosome profiling in Bacillus subtilis shows that under serine limitation, ribosomes pause on the four TCN (N for A, C,
G, and T), but not AGC/AGT serine codons, during translation at a g...
journals.asm.org
February 12, 2025 at 3:27 PM
A novel regulation on the developmental checkpoint protein Sda that controls sporulation and biofilm formation in Bacillus subtilis
#JBacteriol from Yunrong Chai
journals.asm.org/doi/10.1128/...
#JBacteriol from Yunrong Chai
journals.asm.org/doi/10.1128/...
Well done Alicia. A wonderful piece work showing the complexity and beauty of microbial interactions.
Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
🔗
www.biorxiv.org/content/10.1...
🔗
www.biorxiv.org/content/10.1...
The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi
Bacterial□fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix (ECM) in shaping these relationships has remained unclear....
www.biorxiv.org
February 11, 2025 at 8:13 AM
Well done Alicia. A wonderful piece work showing the complexity and beauty of microbial interactions.
Reposted
Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
🔗
www.biorxiv.org/content/10.1...
🔗
www.biorxiv.org/content/10.1...
The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi
Bacterial□fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix (ECM) in shaping these relationships has remained unclear....
www.biorxiv.org
February 11, 2025 at 8:01 AM
Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
🔗
www.biorxiv.org/content/10.1...
🔗
www.biorxiv.org/content/10.1...
Reposted
The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi https://www.biorxiv.org/content/10.1101/2025.02.06.636830v1
February 8, 2025 at 7:16 AM
The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi https://www.biorxiv.org/content/10.1101/2025.02.06.636830v1
Reposted
The US Centers for Disease Control and Prevention (CDC) has mandated that all scientific manuscripts produced by its researchers that are under review at a journal be withdrawn so that certain language relating to gender can be stripped from them.
https://go.nature.com/40YJGp4
https://go.nature.com/40YJGp4
US health agency seeks to cut gender-related terms from scientific papers
The mandate from the Centers for Disease Control and Prevention follows an executive order from president Donald Trump, and applies to research not yet published.
go.nature.com
February 4, 2025 at 7:09 PM
The US Centers for Disease Control and Prevention (CDC) has mandated that all scientific manuscripts produced by its researchers that are under review at a journal be withdrawn so that certain language relating to gender can be stripped from them.
https://go.nature.com/40YJGp4
https://go.nature.com/40YJGp4
Reposted
Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species
PNAS - contributed by Jo Handelsman
www.pnas.org/doi/10.1073/...
PNAS - contributed by Jo Handelsman
www.pnas.org/doi/10.1073/...
February 4, 2025 at 11:58 AM
Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species
PNAS - contributed by Jo Handelsman
www.pnas.org/doi/10.1073/...
PNAS - contributed by Jo Handelsman
www.pnas.org/doi/10.1073/...
Reposted
Nature research paper: Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield
https://go.nature.com/3CvoEVy
https://go.nature.com/3CvoEVy
Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield - Nature
Precise regulation of the phytohormone gibberellin to optimal levels may not only confer alkali–thermal tolerance to Green Revolution rice varieties but may also further enhance their yield, and ATT2, by enabling the fine-tuning of gibberellins, is expected to be a potential new post-Green Revolution gene.
go.nature.com
January 30, 2025 at 7:15 PM
Nature research paper: Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield
https://go.nature.com/3CvoEVy
https://go.nature.com/3CvoEVy
Reposted
Researchers present in Science a sustainable and biodegradable adhesive derived from a natural, microbially produced polyester that also exhibits exceptional adhesive properties. scim.ag/3PTgCZB
Stereomicrostructure-regulated biodegradable adhesives
Commercial adhesives are petroleum-based thermoset networks or nonbiodegradable thermoplastic hot melts, making them ideal targets for replacement by biodegradable alternatives. Poly(3-hydroxybutyrate...
scim.ag
January 28, 2025 at 7:43 PM
Researchers present in Science a sustainable and biodegradable adhesive derived from a natural, microbially produced polyester that also exhibits exceptional adhesive properties. scim.ag/3PTgCZB
Reposted
Super happy to share my first article at @diegromero.bsky.social´s lab, about Bacillus cyclic lipopeptides and how the diversification of structural variants production impacts biological activities!!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Diversification of Lipopeptide Analogues Drives Versatility in Biological Activities
Cyclic lipopeptides (CLPs) are potent secondary metabolites with diverse biological functions. Bacillus strains primarily produce CLPs of three key families, namely, iturins, fengycins, and surfactins...
pubs.acs.org
January 25, 2025 at 1:58 PM
Super happy to share my first article at @diegromero.bsky.social´s lab, about Bacillus cyclic lipopeptides and how the diversification of structural variants production impacts biological activities!!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted
Don’t be glum about the long, cold winter. Look around: the trees are busy, not sleeping. When the temperature permits, cells in this bud are dividing, maturing into flowers, leaves, stems. The cambium, maker of all the trees, is preparing for its spring festivities. Be like a tree: keep growing.
January 15, 2025 at 6:28 PM
Don’t be glum about the long, cold winter. Look around: the trees are busy, not sleeping. When the temperature permits, cells in this bud are dividing, maturing into flowers, leaves, stems. The cambium, maker of all the trees, is preparing for its spring festivities. Be like a tree: keep growing.
Reposted
Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature.
Learn more: scim.ag/4gTAurn
Learn more: scim.ag/4gTAurn
January 15, 2025 at 7:49 PM
Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature.
Learn more: scim.ag/4gTAurn
Learn more: scim.ag/4gTAurn
Reposted
Nature research paper: Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
https://go.nature.com/3PDa9lG
https://go.nature.com/3PDa9lG
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elements in plants and may provide insights into the in vivo roles of many transporters.
go.nature.com
January 15, 2025 at 8:14 PM
Nature research paper: Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
https://go.nature.com/3PDa9lG
https://go.nature.com/3PDa9lG
Reposted
Absolutely breathtaking ….A pan across the stunning star cluster Westerlund 2... 💫👏💫👏💫👏💫👏💫
(Credit: NASA, ESA, the Hubble Heritage Team (STScIAURA), A. Nota (ESASTScI), and the Westerlund 2 Science Team)
(Credit: NASA, ESA, the Hubble Heritage Team (STScIAURA), A. Nota (ESASTScI), and the Westerlund 2 Science Team)
December 28, 2024 at 1:23 AM
Absolutely breathtaking ….A pan across the stunning star cluster Westerlund 2... 💫👏💫👏💫👏💫👏💫
(Credit: NASA, ESA, the Hubble Heritage Team (STScIAURA), A. Nota (ESASTScI), and the Westerlund 2 Science Team)
(Credit: NASA, ESA, the Hubble Heritage Team (STScIAURA), A. Nota (ESASTScI), and the Westerlund 2 Science Team)
Reposted
Reposted
Blue birds huddling together for warmth
December 27, 2024 at 2:32 PM
Blue birds huddling together for warmth
Reposted
Post Doc position on discovering of circadian clock components within the #MicroClock #ERCSyG project at #LeidenUniversity with Ákos T. Kovács @evolvedbiofilm.bsky.social
👉 deadline on 17 January 2025
👉 deadline on 17 January 2025
Join our #MicroClock @microclockerc.bsky.social #ERCSyG team as #Postdoc to discover the components of a bacterial circadian clock
Apply by 17 Jan 2025, if you have experience
-with liquid handling robots/screening of bacterial strains
-in molecular biology of model bacteria
tinyurl.com/2d2c8fe5
Apply by 17 Jan 2025, if you have experience
-with liquid handling robots/screening of bacterial strains
-in molecular biology of model bacteria
tinyurl.com/2d2c8fe5
December 24, 2024 at 2:48 PM
Post Doc position on discovering of circadian clock components within the #MicroClock #ERCSyG project at #LeidenUniversity with Ákos T. Kovács @evolvedbiofilm.bsky.social
👉 deadline on 17 January 2025
👉 deadline on 17 January 2025
Reposted
Our EU project iCULTURE is on BBC!!!!
Of course, we are not trying to producing classical antibiotics but #bacteriocins and other antimicrobial peptides to start with. But once this is achieved, anything is possible.
www.bbc.com/reel/video/p...
Of course, we are not trying to producing classical antibiotics but #bacteriocins and other antimicrobial peptides to start with. But once this is achieved, anything is possible.
www.bbc.com/reel/video/p...
How seaweed could be used to make sustainable antibiotics
A lab in Norway is working on a new method to make antibiotics by training bacteria to eat seaweed.
www.bbc.com
December 26, 2024 at 9:13 AM
Our EU project iCULTURE is on BBC!!!!
Of course, we are not trying to producing classical antibiotics but #bacteriocins and other antimicrobial peptides to start with. But once this is achieved, anything is possible.
www.bbc.com/reel/video/p...
Of course, we are not trying to producing classical antibiotics but #bacteriocins and other antimicrobial peptides to start with. But once this is achieved, anything is possible.
www.bbc.com/reel/video/p...