David Flood
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davidcflood.bsky.social
David Flood
@davidcflood.bsky.social
44 followers 95 following 21 posts

Med-Peds doc, global health researcher, Guatemalaphile, likes to bake bread, Asst Prof @U-Michigan

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davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 9d
The reporting on Summers has been terrible. He was using is power as a mentor to prey on a mentee. Journalists need to stop acting like this was a workplace romance.

www.wsj.com/us-news/larr...

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 13d
He mentally 1-2 days feels better though I recognize it is not logicalLu optimal to have that delay

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 16d
This comment is evergreen

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 19d
Even discounting Kelly's future cash flows at 5-6%, the present value of his contract is ~$45mm, meaning he leaves $20mm on the table by taking the $25mm deal.

But LSU apparently offered to cut out his "duty to mitigate" clause, which allows LSU to offset payments against Kelly's future earnings.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 23d
Please find our comment describing concerns about this review:

www.cochranelibrary.com/cdsr/doi/10....

@mikejohansenmd.medsky.social @hswapnil.medsky.social @rnflex.bsky.social
www.cochranelibrary.com

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 24d
May I ask: Reports from whom? Do you have a reference? I have not seen reporting to this effect.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 26d
@mikejohansenmd.medsky.social The fatal flaw is they pre-specified a clinically relevant absolute risk threshold without considering time horizon or base rate.

The base rate in these trials of <1 year was 0.5%, which is less than the 1% absolute risk reduction they said was clinically significant.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 26d
This RRR is even greater than that for high-intensity statins in meta analyses!

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · 26d
I think in the present era Cochrane probably does more harm than good.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 27
The test characteristics for screening for CKD are very different than for the diseases you mention. The benefits of treatment also different.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 26
The pediatric world is different but I am not convinced of this idea:

bsky.app/profile/rhea...

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 26
Screening is seductive especially to specialists who see the impact of these terrible diseases. But unfortunately screening often is not as effective as we would hope.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 26
Weird. The pdf shows the abstract version not the pubmed version.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 26
The other thing is that the methods of the per protocol analyses are summarized in one paragraph without much detail. No mention in supplement. These analyses are not trivial (including simulation!), like another full paper. I would like to see what assumptions and methods are being used here.

davidcflood.bsky.social
David Flood @davidcflood.bsky.social · Oct 26
This is what I see

Reposted by David Flood

rheaultm.bsky.social
Michelle Rheault, MD @rheaultm.bsky.social · Oct 25
If treatments are available that can help at early stages of most causes of CKD (RAASi, SGLT2i, etc), why WOULDN’T we screen? Economics? How much does saving 20 years of dialysis get you? What about human costs?
www.kireports.org/article/S246...
Urine screening to early diagnose young individuals with CKD: a call for action
Alport syndrome is an inherited disorder of basement membranes leading to progressive chronic kidney disease, hearing loss, and ocular abnormalities in many affected patients. When the authors started...
www.kireports.org