Brian Ratnasinghe
@brianrat.bsky.social
Post-Doc(2029): 👀
PhD(2027): University of Copenhagen - NBI Commic Group
Biophysics Researcher(2024): Medical College of Wisconsin - Mellows Center for Genomic Science and Precision Medicine
Masters(2021): Virginia Tech - Lemkul Lab
PhD(2027): University of Copenhagen - NBI Commic Group
Biophysics Researcher(2024): Medical College of Wisconsin - Mellows Center for Genomic Science and Precision Medicine
Masters(2021): Virginia Tech - Lemkul Lab
Reposted by Brian Ratnasinghe
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 17, 2025 at 8:51 AM
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Reposted by Brian Ratnasinghe
Excited to share a new update to the Drude polarizable force field - phosphorylated amino acids! A long-term project that took quite a bit of effort. Great work with PhD student Laura Gil Pineda, former undergrad Candace Miller, and @alexmackerell.bsky.social
authors.elsevier.com/a/1m2md1SPTB...
authors.elsevier.com/a/1m2md1SPTB...
November 6, 2025 at 1:27 PM
Excited to share a new update to the Drude polarizable force field - phosphorylated amino acids! A long-term project that took quite a bit of effort. Great work with PhD student Laura Gil Pineda, former undergrad Candace Miller, and @alexmackerell.bsky.social
authors.elsevier.com/a/1m2md1SPTB...
authors.elsevier.com/a/1m2md1SPTB...
Reposted by Brian Ratnasinghe
the Martini Pumpkin by my PhD student Isabell Lindahl.
Too much fat though!
TS2CG, Martini3, Martini
@cg-martini.bsky.social
Too much fat though!
TS2CG, Martini3, Martini
@cg-martini.bsky.social
October 27, 2025 at 2:49 PM
the Martini Pumpkin by my PhD student Isabell Lindahl.
Too much fat though!
TS2CG, Martini3, Martini
@cg-martini.bsky.social
Too much fat though!
TS2CG, Martini3, Martini
@cg-martini.bsky.social
Reposted by Brian Ratnasinghe
Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation'
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
October 15, 2025 at 2:41 PM
Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation'
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
Reposted by Brian Ratnasinghe
The 3rd Annual Danish Workshop on Advanced Molecular Simulation. This time in Aarhus
Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation'
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
October 15, 2025 at 7:53 PM
The 3rd Annual Danish Workshop on Advanced Molecular Simulation. This time in Aarhus
Reposted by Brian Ratnasinghe
A new preprint from my group by my PhD student Adria:
No attraction between proteins, they do not induce curvature, but they cluster on membranes.
One of the reasons why mesoscale modeling matters.
www.biorxiv.org/content/10.1...
No attraction between proteins, they do not induce curvature, but they cluster on membranes.
One of the reasons why mesoscale modeling matters.
www.biorxiv.org/content/10.1...
September 18, 2025 at 8:21 AM
A new preprint from my group by my PhD student Adria:
No attraction between proteins, they do not induce curvature, but they cluster on membranes.
One of the reasons why mesoscale modeling matters.
www.biorxiv.org/content/10.1...
No attraction between proteins, they do not induce curvature, but they cluster on membranes.
One of the reasons why mesoscale modeling matters.
www.biorxiv.org/content/10.1...
Reposted by Brian Ratnasinghe
If you’re interested in learning more about protein folding and misfolding, I’ve created a convenient reading list with a few essential papers:
scholar.google.com/citations?us...
scholar.google.com/citations?us...
scholar.google.com/citations?us...
scholar.google.com/citations?us...
August 6, 2025 at 7:01 PM
If you’re interested in learning more about protein folding and misfolding, I’ve created a convenient reading list with a few essential papers:
scholar.google.com/citations?us...
scholar.google.com/citations?us...
scholar.google.com/citations?us...
scholar.google.com/citations?us...
Hey y'all, If any of you are at EBSA this year come check out my poster. You can find my poster at position 332 on Thursday.
This year my poster is about the parameterization of meso scale force field for wood cell wall simulations. It's a fun topic, so def swing by if you're interested.
This year my poster is about the parameterization of meso scale force field for wood cell wall simulations. It's a fun topic, so def swing by if you're interested.
July 1, 2025 at 6:39 AM
Hey y'all, If any of you are at EBSA this year come check out my poster. You can find my poster at position 332 on Thursday.
This year my poster is about the parameterization of meso scale force field for wood cell wall simulations. It's a fun topic, so def swing by if you're interested.
This year my poster is about the parameterization of meso scale force field for wood cell wall simulations. It's a fun topic, so def swing by if you're interested.
Reposted by Brian Ratnasinghe
New €94M research centre for protein design will open at the University of Copenhagen and be led by Dek Woolfson
Funded by the Novo Nordisk Foundation, the centre will operate across the Departments of Biology and & Drug Design and Pharmacology
novonordiskfonden.dk/en/news/new-...
Funded by the Novo Nordisk Foundation, the centre will operate across the Departments of Biology and & Drug Design and Pharmacology
novonordiskfonden.dk/en/news/new-...
New Danish research centre to make designed proteins with vast potential - Novo Nordisk Fonden
novonordiskfonden.dk
June 25, 2025 at 6:53 AM
New €94M research centre for protein design will open at the University of Copenhagen and be led by Dek Woolfson
Funded by the Novo Nordisk Foundation, the centre will operate across the Departments of Biology and & Drug Design and Pharmacology
novonordiskfonden.dk/en/news/new-...
Funded by the Novo Nordisk Foundation, the centre will operate across the Departments of Biology and & Drug Design and Pharmacology
novonordiskfonden.dk/en/news/new-...
Bobo bleps when she sleeps, but doesn't realize she's blepping when she wakes up. It's amazing
May 28, 2025 at 5:50 PM
Bobo bleps when she sleeps, but doesn't realize she's blepping when she wakes up. It's amazing
Reposted by Brian Ratnasinghe
This EO is a lot of words for a rule that basically says, political appointees will overrule scientists in deciding what the government considers factual information.
Restoring Gold Standard Science
By the authority vested in me as President by the Constitution and the laws of the United States of America, including section 7301 of title 5, United
www.whitehouse.gov
May 24, 2025 at 12:58 PM
This EO is a lot of words for a rule that basically says, political appointees will overrule scientists in deciding what the government considers factual information.
Reposted by Brian Ratnasinghe
As of yesterday using publicly available data via Grant Watch grant-watch.us/nih-data.html:
05/24/2025 word cloud depicting 165 unique words or phrases, flagged 10904 times, within 2118 terminated NIH grants.
@standupforscience.bsky.social
@altnih4science.bsky.social
05/24/2025 word cloud depicting 165 unique words or phrases, flagged 10904 times, within 2118 terminated NIH grants.
@standupforscience.bsky.social
@altnih4science.bsky.social
May 25, 2025 at 1:03 PM
As of yesterday using publicly available data via Grant Watch grant-watch.us/nih-data.html:
05/24/2025 word cloud depicting 165 unique words or phrases, flagged 10904 times, within 2118 terminated NIH grants.
@standupforscience.bsky.social
@altnih4science.bsky.social
05/24/2025 word cloud depicting 165 unique words or phrases, flagged 10904 times, within 2118 terminated NIH grants.
@standupforscience.bsky.social
@altnih4science.bsky.social
Reposted by Brian Ratnasinghe
🚨URGENT RESPONSE CALL🚨
🌪️23 LIVES WERE LOST OVERNIGHT AS TORNADOS HIT KY.
KY has one of several regions in the US without 24/7 National Weather Service coverage, due to DOGE cuts. W/out overnight monitoring, ppl don't receive weather warnings.
THIS is how science cuts cost lives.
shorturl.at/JgTjU
🌪️23 LIVES WERE LOST OVERNIGHT AS TORNADOS HIT KY.
KY has one of several regions in the US without 24/7 National Weather Service coverage, due to DOGE cuts. W/out overnight monitoring, ppl don't receive weather warnings.
THIS is how science cuts cost lives.
shorturl.at/JgTjU
Multiple deaths reported in Somerset and London due to late night tornadoes UPDATED
The towns of Somerset and London have been hit particularly hard with many homes and buildings damaged in the early morning hours.
www.weku.org
May 17, 2025 at 4:38 PM
🚨URGENT RESPONSE CALL🚨
🌪️23 LIVES WERE LOST OVERNIGHT AS TORNADOS HIT KY.
KY has one of several regions in the US without 24/7 National Weather Service coverage, due to DOGE cuts. W/out overnight monitoring, ppl don't receive weather warnings.
THIS is how science cuts cost lives.
shorturl.at/JgTjU
🌪️23 LIVES WERE LOST OVERNIGHT AS TORNADOS HIT KY.
KY has one of several regions in the US without 24/7 National Weather Service coverage, due to DOGE cuts. W/out overnight monitoring, ppl don't receive weather warnings.
THIS is how science cuts cost lives.
shorturl.at/JgTjU
Reposted by Brian Ratnasinghe
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Another scoop from Jeff Mervis (@policyhound.bsky.social): NSF's ~1400 grant terminations have disproportionately affected PIs from groups underrepresented in science: women, racial & ethnic minorities, & those with disabilities. 1/3
www.science.org/content/arti...
www.science.org/content/arti...
Trump officials take steps toward a radically different NSF
Efforts to shrink staff, budget, and focus have alarmed members of Congress
www.science.org
May 13, 2025 at 10:09 PM
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Reposted by Brian Ratnasinghe
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
May 13, 2025 at 11:37 PM
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
Reposted by Brian Ratnasinghe
Join us to explore how #MolecularDynamics simulations support and accelerate drug discovery!
🗓️ Sep 29 - Oct 1
📍 Montelino (PG), Umbria, Italy
Read more and register ➡️ bit.ly/3GFShFs
#MDDB #DrugDiscovery #FAIRdata #OpenScience
🗓️ Sep 29 - Oct 1
📍 Montelino (PG), Umbria, Italy
Read more and register ➡️ bit.ly/3GFShFs
#MDDB #DrugDiscovery #FAIRdata #OpenScience
May 8, 2025 at 10:04 AM
Join us to explore how #MolecularDynamics simulations support and accelerate drug discovery!
🗓️ Sep 29 - Oct 1
📍 Montelino (PG), Umbria, Italy
Read more and register ➡️ bit.ly/3GFShFs
#MDDB #DrugDiscovery #FAIRdata #OpenScience
🗓️ Sep 29 - Oct 1
📍 Montelino (PG), Umbria, Italy
Read more and register ➡️ bit.ly/3GFShFs
#MDDB #DrugDiscovery #FAIRdata #OpenScience
Reposted by Brian Ratnasinghe
They are segregationist and this will be open season for discrimination.
“the Attorney General shall initiate appropriate action to repeal or amend the implementing regulations for Title VI of the Civil Rights Act of 1964 for all agencies to the extent they contemplate disparate-impact liability”
“the Attorney General shall initiate appropriate action to repeal or amend the implementing regulations for Title VI of the Civil Rights Act of 1964 for all agencies to the extent they contemplate disparate-impact liability”
April 24, 2025 at 12:32 AM
They are segregationist and this will be open season for discrimination.
“the Attorney General shall initiate appropriate action to repeal or amend the implementing regulations for Title VI of the Civil Rights Act of 1964 for all agencies to the extent they contemplate disparate-impact liability”
“the Attorney General shall initiate appropriate action to repeal or amend the implementing regulations for Title VI of the Civil Rights Act of 1964 for all agencies to the extent they contemplate disparate-impact liability”
Reposted by Brian Ratnasinghe
I just attended a conference in the US. We had one speaker detained and two others turned away at the border.
There are great conferences and science in the US, but with the way things are right now, it’s too risky to attend.
Australian academics refuse to attend US conferences for fear of being detained
‘When academics fear travelling or partnering with US institutions, the impacts ripple through the entire global knowledge ecosystem,’ one says
www.theguardian.com
April 13, 2025 at 11:10 PM
I just attended a conference in the US. We had one speaker detained and two others turned away at the border.
Reposted by Brian Ratnasinghe
📢 Our article calling for a #FAIR database for #MolecularDynamics simulation data has now been peer-reviewed and published in @naturemethods.bsky.social
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
April 4, 2025 at 8:09 AM
📢 Our article calling for a #FAIR database for #MolecularDynamics simulation data has now been peer-reviewed and published in @naturemethods.bsky.social
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
Reposted by Brian Ratnasinghe
Homeland Security secretary Kristi Noem making content in front of the imprisoned men of El Salvador's notorious Terrorism Confinement Center mega-prison www.washingtonpost.com/technology/2...
March 26, 2025 at 11:10 PM
Homeland Security secretary Kristi Noem making content in front of the imprisoned men of El Salvador's notorious Terrorism Confinement Center mega-prison www.washingtonpost.com/technology/2...
Reposted by Brian Ratnasinghe
BREAKING: People are being suspended on X in Turkey for posting videos of these protests against Erdoğan’s corrupt and repressive regime.
Keep sharing everywhere.
Keep sharing everywhere.
March 23, 2025 at 12:20 PM
BREAKING: People are being suspended on X in Turkey for posting videos of these protests against Erdoğan’s corrupt and repressive regime.
Keep sharing everywhere.
Keep sharing everywhere.
Reposted by Brian Ratnasinghe
interesting preprint from Weria Pezeshkian on general material properties of membranes
Lateral tension can lead to membrane neck constriction at low tension & dilation at high tensions
relevant to nuclear pores, ER, mitochondria, Golgi etc
www.biorxiv.org/content/10.1...
Lateral tension can lead to membrane neck constriction at low tension & dilation at high tensions
relevant to nuclear pores, ER, mitochondria, Golgi etc
www.biorxiv.org/content/10.1...
March 14, 2025 at 4:52 PM
interesting preprint from Weria Pezeshkian on general material properties of membranes
Lateral tension can lead to membrane neck constriction at low tension & dilation at high tensions
relevant to nuclear pores, ER, mitochondria, Golgi etc
www.biorxiv.org/content/10.1...
Lateral tension can lead to membrane neck constriction at low tension & dilation at high tensions
relevant to nuclear pores, ER, mitochondria, Golgi etc
www.biorxiv.org/content/10.1...
Reposted by Brian Ratnasinghe
Share with US students who had their offers of admission withdrawn for PhD programs:
Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.
Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.
March 13, 2025 at 12:44 AM
Share with US students who had their offers of admission withdrawn for PhD programs:
Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.
Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.
Reposted by Brian Ratnasinghe
openRxiv has arrived!
We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...
#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv
We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...
#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv
March 11, 2025 at 1:18 PM
openRxiv has arrived!
We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...
#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv
We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...
#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv
Reposted by Brian Ratnasinghe
Come to Denmark 🥚
March 9, 2025 at 12:09 PM
Come to Denmark 🥚