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Andrew Tosolini

@andrewtosolini.bsky.social

570 followers 460 following 7 posts

Senior researcher at The University of Queensland - Ngo and Steyn Labs. Schiavo Lab alumni. Interested in MND/ALS, motor neurons, NMJs, and of course axonal transport. Hobbies include the Socceroos, the Australian Cricket team and Chelsea FC.

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Andrew Tosolini @andrewtosolini.bsky.social · 1d

Do all #NTFs regulate #MotorNeuron axonal transport in vivo?

Our new preprint shows they do not.

#BDNF enhances (shorturl.at/siwFi), #CNTF slows, and #HGF, #NRTN & #proBDNF show no effect.

#AxonalTransport regulation is selective, not universal.

@jamessleigh.bsky.social @uclqsion.bsky.social

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Andrew Tosolini @andrewtosolini.bsky.social · 1d

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Andrew Tosolini @andrewtosolini.bsky.social · Jun 18

A wonderful collaboration. Congratulations to @nicolbirsa.bsky.social & @beccasimkin.bsky.social and all the co-authors #axonaltransport #FUS #MND #ALS #NMJ

Nicol Birsa @nicolbirsa.bsky.social · Jun 18

Very excited to share our latest preprint! We looked at loss and gain of function, innervation, reinnervation, and in vivo axonal transport in a FUS-ALS mouse model!

www.biorxiv.org/content/10.1...

@uclqsion.bsky.social @beccasimkin.bsky.social @andrewtosolini.bsky.social @frattalab.bsky.social

Reposted by Andrew Tosolini

James N. Sleigh @jamessleigh.bsky.social · May 30

Our new paper in Neurobiology of Aging showing that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:

www.sciencedirect.com/science/arti...

@dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social @uclqsion.bsky.social #aging

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Andrew Tosolini @andrewtosolini.bsky.social · May 6

🚨New
@biorxivpreprint.bsky.social
collab b/w Fisher, Cunningham, Gilthorpe &
Schiavo Labs. @mrcharwell.bsky.social @uclqsion.bsky.social @umeauniversitet.bsky.social
Metabolic alterations in the absence of a detectable neuromuscular phenotype in novel humanised SOD1A4V mice.
t.co/u01CG6ctTS

https://www.biorxiv.org/content/10.1101/2025.05.01.650597v1

t.co

Reposted by Andrew Tosolini

James N. Sleigh @jamessleigh.bsky.social · Feb 2

In our latest pre-print, we show that processivity and BDNF-dependent modulation of #AxonalTransport are impaired in aged mice:

www.biorxiv.org/content/10.1...

Well done team! @dvillarroelc.bsky.social @andrewtosolini.bsky.social @alessiovagnoni.bsky.social et al.

@uclqsion.bsky.social #aging

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Andrew Tosolini @andrewtosolini.bsky.social · Nov 30

Congratulations Sean!

Andrew Tosolini @andrewtosolini.bsky.social · Nov 25

A little about me! 🦋 With help from Scholar Goggler scholargoggler.com

Reposted by Andrew Tosolini

Guillaume Jacquemet @guijacquemet.bsky.social · Nov 11

I will try to take on the challenge to highlight some of the cool bioimage analysis tools we use all the time. #BioimageTooloftheDay

I will start with ijp-LaRoMe, a very nifty Fiji plugin that I use all the time to convert ROI to label images and vice versa
github.com/BIOP/ijp-LaR...

GitHub - BIOP/ijp-LaRoMe: some useful function to get Label from ROIs and vice versa , and more!

some useful function to get Label from ROIs and vice versa , and more! - BIOP/ijp-LaRoMe

github.com

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Andrew Tosolini @andrewtosolini.bsky.social · Nov 20

Can you please add me too! Many thanks

Reposted by Andrew Tosolini

Scheiffele Lab @scheiffelelab.bsky.social · Nov 17

Looking forward to AXON2025 - mark your calendars

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Andrew Tosolini @andrewtosolini.bsky.social · Nov 12

Thanks for sharing!