Brian H Mathison
@allthingstox.com
260 followers 240 following 540 posts
Father, husband, scientist, & toxicologist; BA Biochem & Molecular Biology (UCSB); PhD Environmental Toxicology (UCI) 🧬Composite Transcription Factor Decoys. Chemical Carcinogenesis, Genetic Toxicology, & Predictive Technologies brianhmathison.substack.com
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allthingstox.com
Generative Artificial Intelligence (GAI) - Yikes
Note: substack.com/profile/1098...
Reposted by Brian H Mathison
compoundchem.com
I put this to the test with Copilot and yeah, I think it's fair to say that it struggled with the structure of caffeine
A Co-pilot created drawing of a molecule that is definitely not caffeine
allthingstox.com
Seems very little happening with EPA Docket EPA-HQ-OPP-2024-0562 - "Petition Seeking Rulemaking to Modify False or Misleading Statements subsection of the Code of Federal Regulations (CFR)" - Reminding myself to say consistent: substack.com/@allthingsto...
Brian H Mathison PhD (@allthingstox)
⚖️ FIFRA Petition on Misbranding and Uniformity There appears to be minimal recent activity in EPA Docket EPA-HQ-OPP-2024-0562. It will be interesting to see how the matter proceeds, particularly wit...
substack.com
allthingstox.com
Robbins Pathology covers, but doesn’t go into molecular explanations as in an advanced immunology course - I saw references immune capping as part of the B-cell activation mechanism & membrane receptor behavior in immunology years ago. Med. Students have to cover a lot of ground with limited time.
allthingstox.com
Was hoping to hear more about possible solutions & didn’t catch any thoughts on the Surgeon General nominee? Cabinet secretaries serve at the pleasure of the president, and even with the current polling, we may be in for a few more years. Each day a new adventure.
www.pewresearch.org/short-reads/...
allthingstox.com
Interesting, even though SARS-CoV-2’s native spike spacing may limit BCR crosslinking, vaccines can surpass this limitation by altering antigen geometry, conformation, and persistence—driving stronger germinal center reactions and more long-lived plasma cells than natural infection often produces?
allthingstox.com
Great podcast!
kevinfolta.bsky.social
This week's Talking Biotech Podcast is an interview with Dr. Jonathan Howard about his new book, "Everyone Else is Lying to You". We discuss the rise of the bad science and fake scientists now running the CDC and public health. #COVID19 #Vaccination podcasts.apple.com/us/podcast/e...
allthingstox.com
Environmental effects are where some gaps and controversies are highlighted in the EFSA assessment. I try to keep up with litigation and human health aspects where more than $10B has exchanged hands despite regulatory consensus. Tough enough & space limited here.
allthingstox.com
In this instance, best consider the most recent reviews that address monograph 112. Glyphosate is not carcinogenic, mutagenic, or reprotoxic, as concluded by EFSA/ECHA and while acknowledging knowledge gaps, these assessments represent the most comprehensive evaluation of a pesticide ever conducted.
allthingstox.com
In these instances, best cite recent reviews. Glyphosate is not carcinogenic, mutagenic, or reprotoxic, as concluded by EFSA/ECHA and while acknowledging knowledge gaps, these assessments represent the most comprehensive evaluation of a pesticide ever conducted. www.efsa.europa.eu/sites/defaul...
allthingstox.com
Supporting reference:

Parker ND, Johnson SB, King AJ, Amin TB, Swire-Thompson B, Zhang Z, Bylund CL. Assessing Cancer Patients' Exposure to Treatment Misinformation. J Cancer Educ. 2025 Sep 6. doi: 10.1007/s13187-025-02712-0. Epub ahead of print. PMID: 40913676. doi.org/10.1007/s131...
allthingstox.com
Hope not, but.... quick search...

**93% of patients newly diagnosed had been exposed to at least one piece of misinformation about cancer treatments
ufhealth.org/news/2025/st...
**TikTok posts related to cancer found that 81% of posts about cancer “cures” were fake
www.curetoday.com/view/most-cu...
Most Cures to Cancer Shared on TikTok Are Fake, Research Shows | CURE
Findings show that 81% of posts related to cancer on the social media platform TikTok touted fake cures.
www.curetoday.com
allthingstox.com
"If I could explain it to the average person, it wouldn’t have been worth the Nobel Prize." Now try doing that in 280 characters without sending a dollar to Elon. Science meets the attention-span apocalypse.
allthingstox.com
Not much hiking, relaxing
allthingstox.com
I'll need to check out cosmic & celestial influencers first.
allthingstox.com
In available space, EWG is advocacy, not impartial science. Their “Dirty/Clean” lists reduce complex toxicological risks to grade-school labels and miss the key point: fruits & vegetables, organic or conventional, are overwhelmingly important for health. It’s fair to question regulatory frameworks.
allthingstox.com
Believe this was an August filing. The 9th circuit more recently heard arguments regarding Zhang's 'junk science' ruling.

Roundup User Fights Uphill To Revive Cancer Suit At 9th Circ. share.google/rGoN5S25IWUo...