Lightnews — Scholar-powered news

Reposted by Vlad Bondarenko

Pierre-François Lenne @pflenne.bsky.social · 4d

Appreciate Quanta for shining a light on our joint work with Simon Gsell, Sham Tlili (@shamtlili.bsky.social), and Matthias Merkel (@merkellab.bsky.social).

Quanta Magazine @quantamagazine.bsky.social · 5d

Biophysicists are realizing that there is an undervalued element at play in early development: Aside from genes, mechanical forces also steer the growth of embryos. @annademming.bsky.social reports: www.quantamagazine.org/genes-have-h...

Genes Have Harnessed Physics to Help Grow Living Things | Quanta Magazine

The same pulling force that causes “tears” in a glass of wine also shapes embryos. It’s another example of how genes exploit mechanical forces for growth and development.

www.quantamagazine.org

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Çağrı Çevrim @cagricevrim.bsky.social · 5d

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵

Induction of menstruation in mice reveals the regulation of menstrual shedding

During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

www.biorxiv.org

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Naomi Moris @nmoris.bsky.social · 9d

Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏

www.crick.ac.uk/careers-stud...

Moris Lab | Investigating human trunk development using stem cell-based embryo models

www.crick.ac.uk

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Vlad Bondarenko @vladbndk.bsky.social · 14d

Congratulations, Jaroslav! 👏🎊 & greetings from FMI

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Al Jord Lab @aljordlab.bsky.social · 15d

🔴✨ Exciting opportunity : we're hiring a PhD student! ✨🔴

👉 Don't hesitate to apply or spread the word!

⏰ Deadline 30th November 2025

ℹ️ More information and application : www.crg.eu/en/content/t...

@crg.eu @prbb.org

Centre for Genomic Regulation Website

www.crg.eu

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Sara Wickstrom @sarawickstrom.bsky.social · 16d

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

www.nature.com

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Alfonso Martinez Arias @amartinezarias.bsky.social · 22d

THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge

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Vlad Bondarenko @vladbndk.bsky.social · 22d

Wow, what great news 👏 !!!
Huge congrats, @nveits.bsky.social 🥳🥳✨️ looking forward to reading it!

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Nisha Veits @nveits.bsky.social · 22d

How is developmental speed regulated ? 🪰

Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.

www.biorxiv.org/content/10.1...

A big thanks to everyone involved!

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Denis Wirtz @deniswirtz.bsky.social · 23d

We have developed a new workflow to map whole human organs at single-cell resolution, while integrating spatial transcriptomics, proteomics, and metabolomics.

We applied this workflow to map precancerous lesions of the fallopian tubes.

More here: www.biorxiv.org/content/10.1...

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Edouard Hannezo @ehannezo.bsky.social · 26d

Core achievement unlocked!! Congrats to Fabrizio amd all authors!!

Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 26d

Who knew that the perfect pasta sauce could lead to a Nobel Prize? Congrats to ISTA postdoc Fabrizio Olmeda and collaborators for winning the Ig Nobel Prize with their research on mastering Cacio e Pepe. Bravo! 🍝 🎉

Getting hungry? Here´s the recipe for delicious research: https://bit.ly/42vlpHm

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Campàs Lab @campaslab.bsky.social · 25d

I was on a H1B visa for part of my postdoc. Also when I started as Assistant Professor. Several of my postdocs where on H1Bs. This new fee will affect more academia than tech or finance companies because there is no way universities can pay that…

www.nytimes.com/2025/09/19/u...

Trump Says the U.S. Will Institute $100,000 Fee for Skilled Worker Visas

www.nytimes.com

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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 26d

Peer pressure shapes the gut: latest publication in @pnas.org by @lepuslapis.bsky.social, @zhaoshh.bsky.social from @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social with colleagues from @flatironinstitute.org and Princeton University. www.mpi-cbg.de/news-outreac...

Peer pressure shapes the gut

International research team develops mechanical model to explain the shaping of the fruit fly hindgut by forces from neighbouring tissues

www.mpi-cbg.de

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Jan Żylicz @jzylicz.bsky.social · 27d

Genes are not On/Off switches. In a new preprint we show that HDAC3 is key to establish correct transcriptional dose in development. Gr8 work from N. Stamidis @ucph.bsky.social and collab. @jamiehackett.bsky.social @gregersenlab.bsky.social . Huge thx to all authors! www.biorxiv.org/content/10.1...

HDAC3 prevents enhancer hyperactivation to enable developmental transitions

Dynamic gene regulation requires precise cooperation between transcription factors and chromatin modifiers at regulatory elements to achieve not only activation or repression, but also appropriate tra...

www.biorxiv.org

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Benoit Ladoux @bladoux.bsky.social · 28d

Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics.
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...

Regulation of epithelial tissue homeostasis by active trans-epithelial transport

Epithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties o...

www.biorxiv.org

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Swiss National Science Foundation (SNSF) @snsf.ch · 28d

📢 The Federal Council plans to reduce the SNSF's budget by 270 million Swiss francs. The SNSF rejects these cuts. However, in order to be prepared, it has decided to cut costs in consultation with all partners.

➡️https://sohub.io/n2b1

#research #science #CHParl

Federal budget cuts: impact on the SNSF

The SNSF rejects the cuts but is preparing for them. Together with its partners, it has decided to cut costs across several funding schemes.

www.snf.ch

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Claire Richards @clairerich.bsky.social · Sep 15

I made the world’s first bioprinted placenta organoids (mini placentas) and they’ve just been published in @natureportfolio.nature.com

We found that the matrix environment chosen for these organoids was critical to how they grew and developed 🤰

idp.nature.com/authorize?re...

Matrix directs trophoblast differentiation in a bioprinted organoid model of early placental development - Nature Communications

The placenta plays vital roles in supporting fetal development. Here, Richards et al. develop a high-throughput bioprinted trophoblast organoid model to recapitulate the microenvironment of the e...

idp.nature.com

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Julia Batki @juliabatki.bsky.social · Sep 14

I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:

www.fmi.ch/education-ca...

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Mechanobiology Institute @mbisg.bsky.social · Sep 11

Order matters! Aurelien Roux @rouxlab.bsky.social studied the formation of multi-cellular tornado-like structures and regeneration of heads in hydra to share with us how stress fields, topology and geometry of initial tissue organization set the sequence of morphogenesis. #MBIMPG2025

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Vlad Bondarenko @vladbndk.bsky.social · Sep 9

Amazing news! Huge congratulations, Ina & the team💫 👌

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Wolfgang Huber @wkhuber.bsky.social · Sep 9

Join EMBL as a research group leader in AI in biology. EMBL AI is our new initiative aiming to exploit the full potential of ML/AI-based approaches to advance our understanding of the most complex system in the known universe - life on Earth.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
(1/3)

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Ina Sonnen @sonnenlab.bsky.social · Sep 9

Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.

doi.org/10.1101/2025...

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Hans Clevers @hansclevers.bsky.social · Sep 6

1/11 In @science.org: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated. www.science.org/doi/10.1126/...

Epithelial tension controls intestinal cell extrusion

Cell extrusion is essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In th...

www.science.org

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Vlad Bondarenko @vladbndk.bsky.social · Sep 5

📣 It is my pleasure to announce our recent review with Margherita on the current approaches, challenges, and perspectives in studying human maternal-fetal interface using in vitro models www.cell.com/cell-stem-ce... 🚀✨️

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Vlad Bondarenko @vladbndk.bsky.social · Sep 4

Huge congrats, David & the group!! 👏

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