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Reposted by Sarah Melville

Canada Healthwatch 🍁 @canadahealthwatch.ca · Sep 3

London hospital files $20M negligence lawsuit as part of probe into alleged financial fraud https://globalnews.ca/news/11389408/london-hospital-20m-negligence-lawsuit-fraud-investigation/

𝗠𝗼𝗿𝗲 𝗻𝗲𝘄𝘀 ⇢ CanadaHealthwatch.ca 🍁

London Health Sciences Centre has become the first hospital in Canada and one of only a few institutions in the world to have all four major hip and knee replacement surgical robots on site. Orthopaedic surgeon Dr. James Howard spoke with Candace Daniel about the impact of this advancement and how it will establish LHSC as a leader in medical research – Sep 26, 2024

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American Journal of Kidney Diseases @ajkd.bsky.social · 1d

In the Literature by Biruh T. Workeneh, Linda W. Moore, and William E. Mitch:

Revisiting Protein Restriction in Early CKD: Did We Get it Wrong?

bit.ly/AJKD25Worken... (FREE)

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Sarah Melville @sarahkmels.bsky.social · 19h

link to article: www.ajkd.org/article/S027...

Revisiting Protein Restriction in Early CKD: Did We Get it Wrong?

The origins of protein restriction in chronic kidney disease (CKD) date back to the work of Thomas Addis, who demonstrated in the early 20th century that animals fed high-protein diets exhibited kidne...

www.ajkd.org

Reposted by Sarah Melville

American Journal of Kidney Diseases @ajkd.bsky.social · 1d

Perspective by Yuvaram N.V. Reddy, Laura Ellen Ashcraft , and Mallika L. Mendu:

How to Leverage Implementation Science to Achieve Equity in Nephrology Care Delivery

bit.ly/Reddy25Pers

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Reposted by Sarah Melville

Canadian Society of Nephrology @csnscn.bsky.social · 1d

For the #CSNHomecoming

We have section 3 credits available!

The #AskChatCKD 2.0 session with Claudio Rigatto, Alison Thomas and Norm Proulx

Splash slide
Ask ChatCKD 2.0
Section 3 credits

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Dylan MacKay @dylanmackayphd.bsky.social · 1d

I think protein supplementation might become even more important with glipination, ideally in an easy to consume form because otherwise the risk of not consuming enough may increase fast. Hopefully an area that will get some research attention

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Nephrology Journal Club @nephjc.bsky.social · 1d

If you want to stay on top of #NephJC happenings, sign up for our once a week newsletter
www.nephjc.com/newsl...

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Nephrology Journal Club @nephjc.bsky.social · 1d

Up next! ☀️📚 We're going back to the guidelines with KDIGO IgA, which is already out of date (isn’t that awesome) #NephJC

pubmed.ncbi.nlm.nih....

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Sarah Melville @sarahkmels.bsky.social · 1d

A dollar a day, keeps industry bias away, 🤓😃😂

#nephjc

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Nephrology Journal Club @nephjc.bsky.social · 1d

If you want to support #NephJC and get some cool merch, check out
www.nephjc.com/merch...

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Sarah Melville @sarahkmels.bsky.social · 1d

I’ve been suspicious of Cochrane SR/MAs ever since the attack dog name calling incident against Dr. @hswapnil.medsky.social circa 2018…. they were mean & wrong, #nephjc

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Brian Rifkin @brianrifkin.bsky.social · 1d

I’m not even sure the current data actually qualifies for a meta analysis?! We definitely need better quality studies and more patient focused outcomes #NephJC

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Sarah Melville @sarahkmels.bsky.social · 1d

just higher vs. lower plant-based diet…. but it’s ok too many limitations with the analysis, so the conclusion is not reliable, #nephjc

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Sarah Melville @sarahkmels.bsky.social · 1d

yes, patient engagement with collaborating patient partners is important. A requirement for many funding applications too, #nephjc

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Oksana Harasemiw @oksana-h.bsky.social · 1d

#NephJC - yes… it is a failure of nephrology and dialysis that there are so few QOL studies or any studies with patient-relevant and clinically relevant outcomes. This highlights the importance of taking the time and effort to engage stakeholders when developing research questions

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Sarah Melville @sarahkmels.bsky.social · 1d

Relatedly, we talked about this good vs. bad plant-based diet review at journal club last month at our centre…. lots of limitations to this analysis though.
Consensus was too much restriction is not good; QOL is key: pubmed.ncbi.nlm.nih.gov/40081608/

#nephjc

Plant-Based Diet and Chronic Kidney Disease: A Systematic Review and Meta-Analysis - PubMed

Adopting PBD was significantly associated with 26% lower incidences of CKD. Higher intake of PBD showed a dose-dependent relationship with lower risk of CKD incidence and slower CKD progression. Unhea...

pubmed.ncbi.nlm.nih.gov

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Reposted by Sarah Melville

Joel Topf @kidneyboy.bsky.social · 1d

17 trials with 955 patients
DAPA-CKD had 4,300 CKD patients one of half dozen CKD #Flozin trial

This is so under studied it is pathetic.
If you are going to change someone whole lifestyle you need to bring receipts

Do better dieticians

#NephJC

Nephrology Journal Club @nephjc.bsky.social · 1d

T2a
Seventeen RCTs, including 955 patients, were included in the systematic review and 14 were included in at least one outcome-specific meta-analysis. #NephJC

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Nephrology Journal Club @nephjc.bsky.social · 1d

There’s an increasing trend in the market of prescribing expensive probiotics in an attempt to slow CKD progression what’s your take on this? #NephJC

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Paresh Jadav @jadav.bsky.social · 1d

The only thing more restricted than protein is happiness at dinner- HRQOL #NephJC

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Sarah Melville @sarahkmels.bsky.social · 1d

& the GLP-1a’s now too…. I think they’d help maintain balance, #glipination #nephjc

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 1d

No one should be on low protein diet.

It doesn’t work! People who recommend it (such as KDOQI) do not know how to read and interpret studies

Time to move on

#NephJC

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Cristina Popa @nephroseeker.medsky.social · 1d

According to international recommendations, 0.8 g/kg/ day is fit to cover the needs of 97% of the population. 0.66 g—it's the daily average accepted intake #nephjc

knowledge4policy.ec.europa.eu/health-promo...

Dietary recommendations for protein intake for adults and older adults | Knowledge for policy

knowledge4policy.ec.europa.eu

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 1d

Here’s @kidneyboy.bsky.social take on that study

pbfluids.com/2009/02/jour...

#NephJC

Journal Club: low protein diet

Effect of a very low protein diet on outcome: long-term follow-up.This is the long-term follow-up of the B group from the original MDRD study.Enrollment criteria:Age: 18-70Abnormal Cr 1.2-7 women 1…

pbfluids.com

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Nephrology Journal Club @nephjc.bsky.social · 1d

T0f
Given the lack of evidence supporting dietary protein restriction (and potential ⬆️mortality), the 2024 @kdigo.org guidelines currently recommend maintaining a protein intake of 0.8 g/kg body weight per day in adults with CKD G3–G5 (level 2C). #NephJC

kdigo.org/guidelines...

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Reposted by Sarah Melville

Nephrology Journal Club @nephjc.bsky.social · 1d

T0d
Trials examining clinical outcomes in patients with CKD, don’t support any particular threshold of dietary protein. Meta-analyses have demonstrated NO difference in mortality, progression of CKD, or onset to dialysis with low protein vs normal protein diets. #NephJC

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