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plantophagy.bsky.social
Yasin Dagdas
@plantophagy.bsky.social
4K followers 6.5K following 410 posts
Cell biologist excited about autophagy, quality control, evolution, and membrane trafficking. Reads and thinks about academic mentoring, equality & diversity. https://www.cos.uni-heidelberg.de/en/evolutionary-cell-biology
www.cos.uni-heidelberg.de
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Reposted by Yasin Dagdas
juliusbrennecke.bsky.social
Julius Brennecke @juliusbrennecke.bsky.social · 1h
The 'Handler genome' of OSCs, a rare and stably growing cell line that runs a piRNA pathway to silence transposons.

Dominik (@86dominik.bsky.social) assembled the genome of this Drosophila cell line.

Besides making some cool findings, the goal was to turn this into useful resource for the field.
86dominik.bsky.social
Dominik Handler @86dominik.bsky.social · 16h
When transposons jump, genomes diverge - even in cultured cells.
I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. 🧬🧵 (1/12)
Graphical abstract: The Drosophila OSC Genome as a resource for transposon and piRNA biology. The figure illustrates the workflow and key findings. Left: De novo genome assembly using Oxford Nanopore Technologies (ONT) long reads and Hi-C data generates a phased assembly distinguishing unique (blue) and repetitive (orange) sequences. Dot plot comparison between OSC-r1.01 and dm6 reference genomes shows overall synteny with extensive structural variation. Middle: A freely accessible UCSC genome browser session displays multi-omics data tracks including gene models, transposon insertions, chromatin accessibility, transcription, small RNAs, and histone modifications. Right: New insights into flamenco piRNA cluster biology reveal >730 kb transcribed from a single promoter without major splicing. Tethering assays demonstrate long-range silencing effects across the locus, and genome browser tracks show coordinated regulation of piRNA production, transcription, and chromatin state. This resource enables comprehensive studies of transposon regulation and piRNA pathway function in a widely-used Drosophila cell line.
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Reposted by Yasin Dagdas
86dominik.bsky.social
Dominik Handler @86dominik.bsky.social · 16h
When transposons jump, genomes diverge - even in cultured cells.
I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. 🧬🧵 (1/12)
Graphical abstract: The Drosophila OSC Genome as a resource for transposon and piRNA biology. The figure illustrates the workflow and key findings. Left: De novo genome assembly using Oxford Nanopore Technologies (ONT) long reads and Hi-C data generates a phased assembly distinguishing unique (blue) and repetitive (orange) sequences. Dot plot comparison between OSC-r1.01 and dm6 reference genomes shows overall synteny with extensive structural variation. Middle: A freely accessible UCSC genome browser session displays multi-omics data tracks including gene models, transposon insertions, chromatin accessibility, transcription, small RNAs, and histone modifications. Right: New insights into flamenco piRNA cluster biology reveal >730 kb transcribed from a single promoter without major splicing. Tethering assays demonstrate long-range silencing effects across the locus, and genome browser tracks show coordinated regulation of piRNA production, transcription, and chromatin state. This resource enables comprehensive studies of transposon regulation and piRNA pathway function in a widely-used Drosophila cell line.
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Reposted by Yasin Dagdas
teamthomma.bsky.social
Team Thomma @teamthomma.bsky.social · 17h
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
biorxiv-plants.bsky.social
bioRxiv Plant Bio @biorxiv-plants.bsky.social · 12d
Differential contributions of an antimicrobial effector from Verticillium dahliae to virulence and tomato microbiota assembly across natural soils https://www.biorxiv.org/content/10.1101/2025.09.30.679524v1
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Reposted by Yasin Dagdas
djgibbs.bsky.social
Dan Gibbs 🌱🧬 @djgibbs.bsky.social · 23h
We are advertising a PhD project investigating a cellular mechanism that ensures protein quality control during mRNA translation in plants. Please get in touch on here or via email if you are interested and I can provide further details!

Lab website: sites.google.com/site/danielg...
Daniel Gibbs Lab
Welcome to the lab website of Professor Daniel Gibbs @ University of Birmingham
sites.google.com
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Reposted by Yasin Dagdas
plantubiquitin.bsky.social
Greg Vert @plantubiquitin.bsky.social · 1d
Great work by julien Spielmann now published in @theplantjournal.bsky.social.
onlinelibrary.wiley.com/doi/10.1111/...
Canonical tyrosine‐based motifs are required for constitutive endocytosis and polarity of IRT1 and contribute to metal uptake
Control of IRT1 cell surface levels is critical for plant iron uptake from the soil and was previously shown to be regulated by ubiquitin-mediated endocytosis upon non-iron metal excess. Here, we she...
onlinelibrary.wiley.com
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Reposted by Yasin Dagdas
imbavienna.bsky.social
Institute of Molecular Biotechnology @imbavienna.bsky.social · 1d
🔬 👩🏻🔬 🧪 What’s it like doing a PhD between two labs? In our latest Behind the Science, Júlia Portell i de Montserrat, shared PhD student in the Brennecke lab at IMBA and the Plaschka lab at the Research Institute of Molecular Pathology, tells us more about her unusual but rewarding journey:
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Reposted by Yasin Dagdas
typaslab.bsky.social
Typas Lab @typaslab.bsky.social · 2d
Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
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Reposted by Yasin Dagdas
pedrobeltrao.bsky.social
Pedro Beltrao @pedrobeltrao.bsky.social · 6d
new preprint: Ubiquitin is a protein modification linked with degradation but known to regulate other functions. Over 100k ubiquitination sites have been discovered and here we (@julianvangerwen.bsky.social + others) try to prioritize those most critical to the cell www.biorxiv.org/content/10.1...
The functional landscape of the human ubiquitinome
Protein ubiquitination regulates cell biology through diverse avenues, from quality control-linked protein degradation to signaling functions such as modulating protein-protein interactions and enzyme...
www.biorxiv.org
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Reposted by Yasin Dagdas
michaelraissig.bsky.social
Michael Raissig @michaelraissig.bsky.social · 2d
Happy to share our recent thoughts on how grasses form and pattern stomata
doi.org/10.1016/j.pb...
🌾From fate establishment, through within-file patterning to dumbbell formation🌾
Congrats to
@lbmountain.bsky.social
on getting two publications out in a single day - a first for the lab!
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plantophagy.bsky.social
Yasin Dagdas @plantophagy.bsky.social · 2d
Congrats @hohmannulrich.bsky.social !!! They are so lucky to have you! Looking forward to hearing all the cool things Hohmann lab will discover...
hohmannulrich.bsky.social
Ulrich Hohmann @hohmannulrich.bsky.social · 2d
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
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Reposted by Yasin Dagdas
hohmannulrich.bsky.social
Ulrich Hohmann @hohmannulrich.bsky.social · 2d
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
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Reposted by Yasin Dagdas
juliusbrennecke.bsky.social
Julius Brennecke @juliusbrennecke.bsky.social · 2d
Off he is ...

Ulrich is one of the most remarkable scientists I had the pleasure to work with. I learned so much from him about biochemistry, proteins, structural biology, and so much more.

Great people make great things happen.
The really great people are rare.
Ulrich is one of them ...
hohmannulrich.bsky.social
Ulrich Hohmann @hohmannulrich.bsky.social · 2d
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
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Reposted by Yasin Dagdas
talbotlabtsl.bsky.social
Nick Talbot @talbotlabtsl.bsky.social · 2d
New PhD opportunity in my group @thesainsburylab.bsky.social through the BBSRC NRP DTP Programme - see details of host to apply below

biodtp.norwichresearchpark.ac.uk/projects/van...
Vanishing Virulence: Investigating pathogenicity loss in a plant pathogenic fungus (TALBOT_T26DTP) | Doctoral Training Partnership
What makes a plant killer lose its edge? This project will investigate why fungal pathogens lose virulence when they are grown in laboratory culture away from their host plant. Use cutting-edge…
biodtp.norwichresearchpark.ac.uk
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Reposted by Yasin Dagdas
philcarella.bsky.social
Phil Carella @philcarella.bsky.social · 2d
New opportunity to undertake a PhD in my group ⁦‪at the John Innes Centre - if you’re interested in plant immunity and evolution check out the link!
Understanding Host Compatibility in the Marchantia-Phytophthora System (CARELLA_J26DTP) | Doctoral Training Partnership
The fossil record demonstrates that filamentous microbes invaded ancient plant cells with intracellular hyphal structures over 450 million years ago. To this day, a rich diversity of extant land plant...
biodtp.norwichresearchpark.ac.uk
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Reposted by Yasin Dagdas
estukenbrock.bsky.social
Eva Stukenbrock @estukenbrock.bsky.social · 3d
Professorship in plant genetics.
The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
www.berufungen.uni-kiel.de
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Reposted by Yasin Dagdas
kaspervangelderen.bsky.social
Kasper van Gelderen @kaspervangelderen.bsky.social · 4d
New paper from Karen Halliday, @andruromanowski.bsky.social and Mengke Zhou, showing how PIF7 interacts with and inhibits phyA and can actually cause it to move to the cytosol!
www.biorxiv.org/content/bior...
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Reposted by Yasin Dagdas
rensingstefan.bsky.social
Stefan A. Rensing @rensingstefan.bsky.social · 4d
Very happy and proud to share the #Spirogyra genome: 50 Mbp small, lacking almost all plastid division proteins and many transcription factors. Kudos to all the many people involved in this multi year project!
@jandevries.bsky.social
@watertoland.bsky.social
www.biorxiv.org/content/10.1...
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plantophagy.bsky.social
Yasin Dagdas @plantophagy.bsky.social · 4d
#Caturday in full swing
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Reposted by Yasin Dagdas
michaelraissig.bsky.social
Michael Raissig @michaelraissig.bsky.social · 4d
Our paper comparing stomata of the three annual Brachypodium species is out 🌾
bmcplantbiol.biomedcentral.com/articles/10....
A great collaborative effort between @lbmountain.bsky.social, & our friends at University of Silesia (Alexander Betekhtin and Anna Milewska-Hendel). Funded by @dfg.de and NAWA
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Reposted by Yasin Dagdas
plantevolution.bsky.social
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 4d
Congrats, Joe Ecker @salkinstitute.bsky.social, to receiving the McClintock Prize! Joe has been a visionary leader of the field of genetics and genomics – not only for plants – for decades
www.salk.edu/news-release...
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Reposted by Yasin Dagdas
thesainsburylab.bsky.social
The Sainsbury Laboratory @thesainsburylab.bsky.social · 4d
Huge congratulations to PhD students @lenaknorr.bsky.social, from the Ma group, and @amiralito.bsky.social, from the @kamounlab.bsky.social, for their 2025 ASM poster awards! 🎉🌱
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Reposted by Yasin Dagdas
bealelab.bsky.social
Rupert Beale @bealelab.bsky.social · 5d
Do you want to do a PhD with me and Mike Devine? Of course you do! Or if not, maybe you know someone who does? @devinelab.bsky.social www.crick.ac.uk/careers-stud...
Beale & Devine Lab | Role of the V1H subunit of the V-ATPase in neurons and cell-autonomous immune responses
www.crick.ac.uk
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Reposted by Yasin Dagdas
cagricevrim.bsky.social
Çağrı Çevrim @cagricevrim.bsky.social · 5d
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
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Reposted by Yasin Dagdas
currentbiology.bsky.social
Current Biology @currentbiology.bsky.social · 5d
Check out our newest issue where we interview Amy Gladfelter, who studies how extreme cells are organized in space and time at Duke University. Read the interview to find out about Amy's greatest research ambitions and more! www.cell.com/current-biol...
Amy Gladfelter
Interview with Amy Gladfelter, who studies how extreme cells are organized in space and time at Duke University.
www.cell.com
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Reposted by Yasin Dagdas
ryanlab.bsky.social
RyanLab_TCD @ryanlab.bsky.social · 5d
Exciting study from @frisophagy.bsky.social in @chinnery in the Chinnery lab @mrc-mbu.bsky.social. Congratulations to all authors involved in the study! #mitochondria

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations | Science
www.science.org/doi/10.1126/...
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...
www.science.org
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