Nick Fisher
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nef.bsky.social
Nick Fisher
@nef.bsky.social
530 followers 410 following 1.4K posts

Biochemist (respiratory & photosynthetic bioenergetics). Ph.D., Visiting Fellow, bibliophile, Mahlerian, feral cat dad. Also other things. Google Scholar: http://bit.ly/2vpjBP1

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nef.bsky.social
Nick Fisher @nef.bsky.social · Nov 6
Hello new folks! Thanks for stopping by. Sometimes I post about biochemistry, but it’s mostly cats/classical music/books/things in my garden here. Live from Cornwall. Beardy, generally worn down by academia.

nef.bsky.social
Nick Fisher @nef.bsky.social · 13h
A cowpea study (genetic mapping of photosynthetic responses associated with cold stress) I was involved with a while ago. Good to see it in print!
jxbotany.bsky.social Journal of Experimental Botany @jxbotany.bsky.social · 16h
☀️🧬 RESEARCH 🧬☀️

This work introduces Linkage Integration Hypothesis Testing (LIgHT) for mechanistic studies of natural variations, exemplified by photosynthetic regulatory mechanisms that underlie natural variations to abiotic stress - Hoh et al.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪
Fig. 7.Summary of the LIgHT approach results and model, which shows genetically determined photosynthetic responses to chilling stress. Using high-throughput phenotyping and the LIgHT approach, we tested three main possible limitations: PSII limitation (A), PSI limitation (B), and NLM (C). Through the co-linkage test in LIgHT step 2, we confirmed that PSII limitation is the primary limitation under chilling stress, not PSI limitation or NLM. In LIgHT step 3, genetically modulated PSII inhibition mechanisms (Chrs 4 and 9) in response to chilling were defined. Chilling induces increased pmf (D), excitation pressure on QA (E), and photoinhibition (F) by substantially increasing photodamage, with a minor decrease in PSII repair.

Reposted by Nick Fisher

jxbotany.bsky.social
Journal of Experimental Botany @jxbotany.bsky.social · 16h
☀️🧬 RESEARCH 🧬☀️

This work introduces Linkage Integration Hypothesis Testing (LIgHT) for mechanistic studies of natural variations, exemplified by photosynthetic regulatory mechanisms that underlie natural variations to abiotic stress - Hoh et al.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪
Fig. 7.Summary of the LIgHT approach results and model, which shows genetically determined photosynthetic responses to chilling stress. Using high-throughput phenotyping and the LIgHT approach, we tested three main possible limitations: PSII limitation (A), PSI limitation (B), and NLM (C). Through the co-linkage test in LIgHT step 2, we confirmed that PSII limitation is the primary limitation under chilling stress, not PSI limitation or NLM. In LIgHT step 3, genetically modulated PSII inhibition mechanisms (Chrs 4 and 9) in response to chilling were defined. Chilling induces increased pmf (D), excitation pressure on QA (E), and photoinhibition (F) by substantially increasing photodamage, with a minor decrease in PSII repair.

nef.bsky.social
Nick Fisher @nef.bsky.social · 16h
I found this one in a recent purchase. It’s not transferable.
A second class weekly ticket between East Finchley and Mile End. £3.65.

nef.bsky.social
Nick Fisher @nef.bsky.social · 18h
Sally ❤️

nef.bsky.social
Nick Fisher @nef.bsky.social · 2d
I'm a big fan. It's a ridiculously heavy biennial cropper. Scruffy apples, sweet, lots of esters, popular with the village!

nef.bsky.social
Nick Fisher @nef.bsky.social · 2d
Still a few scruffy apples around - Pitmaston Pineapple I think? - which at this time of year, and after a couple of hard frosts, taste more of pear than anything else.
Yellow apples on a bare tree. Very sweet, esters.

nef.bsky.social
Nick Fisher @nef.bsky.social · 2d
Similarly, last night I dropped an extremely buttery piece of toast on my trousers, and it landed the right side up.

nef.bsky.social
Nick Fisher @nef.bsky.social · 3d
Memories of an antimalarial conference years ago when one decorated researcher accused another of being a 'mouse doctor'.
zenbrainest.bsky.social Bryan Roth @zenbrainest.bsky.social · 3d
My favorite from an @hhmi.org scientist: “the great thing about optogenetics is it keeps the riff raff out of the field.”
bita137.bsky.social Bita Moghaddam @bita137.bsky.social · 9d
Heard an established successful neuroscientist dismissing junior scientists as "people at the bottom" 🤦‍♀️

You folks with lots of research funds & power: young scientists more than ever need our respect and support even if you don't agree with their ideas and approaches
#sfn2025

Reposted by Nick Fisher

zenbrainest.bsky.social
Bryan Roth @zenbrainest.bsky.social · 3d
My favorite from an @hhmi.org scientist: “the great thing about optogenetics is it keeps the riff raff out of the field.”
bita137.bsky.social Bita Moghaddam @bita137.bsky.social · 9d
Heard an established successful neuroscientist dismissing junior scientists as "people at the bottom" 🤦‍♀️

You folks with lots of research funds & power: young scientists more than ever need our respect and support even if you don't agree with their ideas and approaches
#sfn2025

nef.bsky.social
Nick Fisher @nef.bsky.social · 5d
There's a Nick Drake tribute concert from 2010 on BBC4 at 2215 tonight, which might be your cup of tea.

nef.bsky.social
Nick Fisher @nef.bsky.social · 6d
No greater danger according to my nan than slightly damp clothing.

nef.bsky.social
Nick Fisher @nef.bsky.social · 7d
He’s decided that the best way to negotiate the staircase is by sliding down on his head, and I say don’t knock it until you’ve tried it.
A malfunctioning cat.

nef.bsky.social
Nick Fisher @nef.bsky.social · 9d
Welcoming in the cold snap with a spritz aperitivo, because why not, damn your eyes.

nef.bsky.social
Nick Fisher @nef.bsky.social · 9d
Definitely colder, the cats have moved in for the evening.

nef.bsky.social
Nick Fisher @nef.bsky.social · 9d
Alert for growlers from the settee.

nef.bsky.social
Nick Fisher @nef.bsky.social · 9d
Always good to read about a live beaked whale sighting (especially this one).

Reposted by Nick Fisher

theguardian.com
The Guardian @theguardian.com · 9d
These rare whales had never been seen alive. Then a team in Mexico sighted two
These rare whales had never been seen alive. Then a team in Mexico sighted two
The search for a gingko-toothed beaked whale had taken five years, when a thieving albatross nearly ruined it all
www.theguardian.com

nef.bsky.social
Nick Fisher @nef.bsky.social · 10d
Yes I had one catch a nesting house martin a year or so ago. Not on, stick to pigeons!

nef.bsky.social
Nick Fisher @nef.bsky.social · 12d
No room for Merv Hughes, and David Boon, who heroically drank 52 cans of beer on a flight from Australia to the UK, at 94? Scandalous.

nef.bsky.social
Nick Fisher @nef.bsky.social · 14d
Interesting chap Borodin. He was also a very accomplished organic chemist (and professor of such).

nef.bsky.social
Nick Fisher @nef.bsky.social · 14d
A rare appearance of Mozart in Wadebridge (Cornwall) this weekend. I'll be there, but not singing, THANK HEAVENS.
Mozart Vespers and Missa Brevis (K. 194) by the Wadebridge Choral Society + soloists, Sat. 15 Nov.

nef.bsky.social
Nick Fisher @nef.bsky.social · 15d
Not all bad mind you, it's a LD/Lab/Green/Ind/MK alliance running the county council.

nef.bsky.social
Nick Fisher @nef.bsky.social · 17d
I’ll DM you my details. You should let me cover the cost of postage, at least. Or let me know a favourite charity of yours.